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L. Prézeau · SciRah

Researcher profile · Semantic Scholar

L. Prézeau

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L. Prézeau — researcher profile on SciRah

h-index: 48
Works: 129
Citations: 9,114

Most-cited papers

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
J. Pin, T. Galvez, L. Prézeau
2003Pharmacology and Therapeutics650 citations
Semantic Scholar
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization
D. Maurel, Laetitia Comps-Agrar, C. Brock, M. Rives +8 more
2008Nature Methods506 citations Open access
Semantic Scholar
Closed state of both binding domains of homodimeric mGlu receptors is required for full activity
J. Kniazeff, Anne-Sophie Bessis, D. Maurel, H. Ansanay +2 more
2004Nature Structural &Molecular Biology284 citations
Semantic Scholar
Dimers and beyond: The functional puzzles of class C GPCRs.
J. Kniazeff, L. Prézeau, P. Rondard, J. Pin +1 more
2011Pharmacology and Therapeutics233 citations
Semantic Scholar
A Single Subunit (GB2) Is Required for G-protein Activation by the Heterodimeric GABAB Receptor*
B. Duthey, S. Caudron, J. Perroy, B. Bettler +3 more
2002Journal of Biological Chemistry206 citations Open access
Semantic Scholar
Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors
C. Goudet, Florence Gaven, J. Kniazeff, C. Vol +5 more
2003Proceedings of the National Academy of Sciences of the United States of America197 citations Open access
Semantic Scholar
Allosteric functioning of dimeric class C G‐protein‐coupled receptors
J. Pin, J. Kniazeff, Jian-Feng Liu, Virginie Binet +3 more
2005The FEBS Journal159 citations
Semantic Scholar
Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR
V. Hlaváčková, C. Goudet, J. Kniazeff, Alice Ziková +6 more
2005EMBO Journal155 citations Open access
Semantic Scholar
The Heptahelical Domain of GABAB2 Is Activated Directly by CGP7930, a Positive Allosteric Modulator of the GABAB Receptor*
Virginie Binet, C. Brajon, L. Le Corre, F. Acher +2 more
2004Journal of Biological Chemistry154 citations Open access
Semantic Scholar
Activation mechanism of the heterodimeric GABA(B) receptor.
J. Pin, J. Kniazeff, Virginie Binet, Jian-Feng Liu +7 more
2004Biochemical Pharmacology149 citations
Semantic Scholar
Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration
M. Rives, C. Vol, Yugo Fukazawa, N. Tinel +5 more
2009EMBO Journal129 citations Open access
Semantic Scholar
Asymmetric Functioning of Dimeric Metabotropic Glutamate Receptors Disclosed by Positive Allosteric Modulators*
C. Goudet, J. Kniazeff, V. Hlaváčková, F. Malhaire +5 more
2005Journal of Biological Chemistry121 citations Open access
Semantic Scholar
A model for the functioning of family 3 GPCRs.
M. Parmentier, L. Prézeau, J. Bockaert, J. Pin
2002TIPS - Trends in Pharmacological Sciences115 citations
Semantic Scholar
Functional crosstalk between GPCRs: with or without oligomerization.
L. Prézeau, M. Rives, Laetitia Comps-Agrar, D. Maurel +2 more
2010Current opinion in pharmacology (Print)114 citations
Semantic Scholar
The activation mechanism of class-C G-protein coupled receptors
J. Pin, J. Kniazeff, C. Goudet, Anne-Sophie Bessis +5 more
2004112 citations Open access
Semantic Scholar
Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists
Anne-Sophie Bessis, P. Rondard, Florence Gaven, I. Brabet +4 more
2002Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor.
Michaela Havlíčková, L. Prézeau, B. Duthey, B. Bettler +2 more
2002Molecular Pharmacology102 citations
Semantic Scholar
The oligomeric state sets GABAB receptor signalling efficacy
Laetitia Comps-Agrar, J. Kniazeff, Lenea Nørskov-Lauritsen, D. Maurel +7 more
2011EMBO Journal101 citations Open access
Semantic Scholar
Sequential Inter- and Intrasubunit Rearrangements During Activation of Dimeric Metabotropic Glutamate Receptor 1
V. Hlaváčková, U. Zabel, D. Franková, Julia Bätz +5 more
2012Science Signaling92 citations
Semantic Scholar
Real-Time Analysis of Agonist-Induced Activation of Protease-Activated Receptor 1/Gαi1 Protein Complex Measured by Bioluminescence Resonance Energy Transfer in Living Cells
M. Ayoub, D. Maurel, Virginie Binet, M. Fink +3 more
2007Molecular Pharmacology91 citations
Semantic Scholar
The complexity of their activation mechanism opens new possibilities for the modulation of mGlu and GABAB class C G protein-coupled receptors.
P. Rondard, C. Goudet, J. Kniazeff, J. Pin +1 more
2011Neuropharmacology86 citations
Semantic Scholar
Allosteric Modulators of GABAB Receptors: Mechanism of Action and Therapeutic Perspective
J. Pin, L. Prézeau
2007Current Neuropharmacology83 citations Open access
Semantic Scholar
Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
D. Moreno-Delgado, Thor C. Møller, J. Ster, J. Giraldo +10 more
2017eLife78 citations Open access
Semantic Scholar
A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate
A. Levoye, J. Zwier, A. Jaracz-Ros, L. Klipfel +8 more
2015Frontiers in Endocrinology73 citations Open access
Semantic Scholar
Common Structural Requirements for Heptahelical Domain Function in Class A and Class C G Protein-coupled Receptors*
Virginie Binet, B. Duthey, Jennifer Lécaillon, C. Vol +4 more
2007Journal of Biological Chemistry70 citations Open access
Semantic Scholar
G‐protein‐coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors
J. Pin, Laetitia Comps-Agrar, D. Maurel, Carine Monnier +5 more
2009Journal of Physiology69 citations Open access
Semantic Scholar
Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor
Jun-Ke Liu, Hengmin Tang, Chan-Juan Xu, Sheng-Nan Zhou +8 more
2022Nature Communications63 citations Open access
Semantic Scholar
Quantitative Phosphoproteomics Unravels Biased Phosphorylation of Serotonin 2A Receptor at Ser280 by Hallucinogenic versus Nonhallucinogenic Agonists
Samah Karaki, C. Bécamel, Samy Murat, Clotilde Mannoury la Cour +5 more
2014Molecular & Cellular Proteomics62 citations Open access
Semantic Scholar
The chemokine CXC4 and CC2 receptors form homo‐ and heterooligomers that can engage their signaling G‐protein effectors and βarrestin
Sylvain Armando, J. Quoyer, Viktorya Lukashova, Arhamatoulaye Maiga +5 more
2014The FASEB Journal62 citations Open access
Semantic Scholar
The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation.
Marie Jarry, M. Diallo, C. Lecointre, L. Desrues +9 more
2010Biochemical Journal61 citations Open access
Semantic Scholar
Biased signaling regulates the pleiotropic effects of the urotensin II receptor to modulate its cellular behaviors
C. Brulé, N. Perzo, J. Joubert, X. Sainsily +3 more
2014The FASEB Journal48 citations
Semantic Scholar
Positive Allosteric Modulators for γ-Aminobutyric AcidB Receptors Open New Routes for the Development of Drugs Targeting Family 3 G-Protein-Coupled Receptors
J. Pin, M. Parmentier, L. Prézeau
2001Molecular Pharmacology45 citations
Semantic Scholar
Up-regulation of GABAB Receptor Signaling by Constitutive Assembly with the K+ Channel Tetramerization Domain-containing Protein 12 (KCTD12)
Klara Ivankova, R. Turecek, Thorsten Fritzius, Riad Seddik +7 more
2013Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Stimulation by Glutamate Receptors of Arachidonic Acid Release Depends on the Na / Ca 2 Exchanger in Neuronal Cells
Aline Dumuis, M. Sebben, Laurent Fagni, L. Prézeau +4 more
200540 citations
Semantic Scholar
Functional Characterisation of Eel Dopamine D2 Receptors and Involvement in the Direct Inhibition of Pituitary Gonadotrophins
C. Jolly, K. Rousseau, L. Prézeau, C. Vol +3 more
2016Journal of neuroendocrinology39 citations
Semantic Scholar
SGIP1 alters internalization and modulates signaling of activated cannabinoid receptor 1 in a biased manner.
A. Hájková, Šárka Techlovská, M. Dvorakova, J. N. Chambers +4 more
2016Neuropharmacology37 citations Open access
Semantic Scholar
The Second Intracellular Loop of Metabotropic Glutamate Receptors Recognizes C Termini of G-protein α-Subunits*
Michaela Havlíčková, J. Blahos, I. Brabet, Jian-Feng Liu +3 more
2003Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics
Thor C. Møller, J. Hottin, C. Clerté, J. Zwier +7 more
2018Scientific Reports36 citations Open access
Semantic Scholar
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to G protein-coupled receptor oligomerization.
Laetitia Comps-Agrar, D. Maurel, P. Rondard, J. Pin +2 more
2011Methods in molecular biology36 citations
Semantic Scholar
Nitric Oxide-Induced Blockade of NMDA Receptors
O. Manzoni, L. Prézeau, P. Marin, Solange Deshager +2 more
2013Neuron32 citations Open access
Semantic Scholar
G protein‐coupled receptors can control the Hippo/YAP pathway through Gq signaling
Diana Zindel, Patrick Mensat, C. Vol, Z. Homayed +8 more
2021The FASEB Journal30 citations
Semantic Scholar
Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling
Diana Zindel, Sandra Engel, A. Bottrill, J. Pin +5 more
2016Biochemical Journal30 citations Open access
Semantic Scholar
GPCR interaction as a possible way for allosteric control between receptors.
J. Pin, J. Kniazeff, L. Prézeau, Jiangbo Liu +1 more
2019Molecular and Cellular Endocrinology29 citations Open access
Semantic Scholar
Further insights into GPR179: expression, localization, and associated pathogenic mechanisms leading to complete congenital stationary night blindness.
Elise Orhan, L. Prézeau, S. El Shamieh, K. Bujakowska +8 more
2013Investigative Ophthalmology and Visual Science29 citations
Semantic Scholar
Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction
Mathieu Oosterlaken, Angelina Rogliardo, T. Lipina, Pierre-André Lafon +20 more
2025Nature28 citations Open access
Semantic Scholar
The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features
H. Castel, L. Desrues, J. Joubert, M. Tonon +4 more
2017Frontiers in Endocrinology28 citations Open access
Semantic Scholar
A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers
Jordi Haubrich, Joan Font, R. Quast, A. Goupil-Lamy +7 more
2021Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
A Proteomic Analysis Reveals the Interaction of GluK1 Ionotropic Kainate Receptor Subunits with Go Proteins
Izabela Rutkowska-Wlodarczyk, M. I. Aller, S. Valbuena, J. Bologna +2 more
2015Journal of Neuroscience27 citations Open access
Semantic Scholar
Among the twenty classical L-amino acids, only glutamate directly activates metabotropic glutamate receptors.
Mélanie Frauli, P. Neuville, C. Vol, J. Pin +1 more
2006Neuropharmacology27 citations
Semantic Scholar
Targeting the Brain with Single-Domain Antibodies: Greater Potential Than Stated So Far?
Mireille Elodie Tsitokana, Pierre-André Lafon, L. Prézeau, J. Pin +1 more
2023International Journal of Molecular Sciences23 citations Open access
Semantic Scholar

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