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H. Tsubouchi · SciRah

Researcher profile · Semantic Scholar

H. Tsubouchi

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H. Tsubouchi — researcher profile on SciRah

h-index: 60
Works: 453
Citations: 16K

Most-cited papers

Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
S. Watanabe, E. Hashimoto, K. Ikejima, H. Uto +16 more
2015Journal of gastroenterology326 citations Open access
Semantic Scholar
Evidence-based clinical practice guidelines for liver cirrhosis 2015
H. Fukui, H. Saito, Y. Ueno, H. Uto +15 more
2016Journal of gastroenterology287 citations Open access
Semantic Scholar
Simeprevir with peginterferon/ribavirin for treatment-naïve hepatitis C genotype 1 patients in Japan: CONCERTO-1, a phase III trial.
N. Hayashi, N. Izumi, H. Kumada, T. Okanoue +7 more
2014Journal of Hepatology145 citations
Semantic Scholar
Nationwide survey for primary sclerosing cholangitis and IgG4‐related sclerosing cholangitis in Japan
A. Tanaka, S. Tazuma, K. Okazaki, H. Tsubouchi +2 more
2014Journal of hepato-biliary-pancreatic sciences125 citations Open access
Semantic Scholar
Guidelines for the management of primary biliary cirrhosis
A. Komori, A. Tanaka, H. Takikawa, H. Tsubouchi +15 more
2014Hepatology Research113 citations Open access
Semantic Scholar
Once-daily simeprevir with peginterferon and ribavirin for treatment-experienced HCV genotype 1-infected patients in Japan: the CONCERTO-2 and CONCERTO-3 studies
N. Izumi, N. Hayashi, H. Kumada, T. Okanoue +7 more
2014Journal of gastroenterology100 citations
Semantic Scholar
Incidence of and risk factors for hepatocellular carcinoma in primary biliary cirrhosis: National data from Japan
K. Harada, J. Hirohara, Y. Ueno, T. Nakano +4 more
2013Hepatology88 citations Open access
Semantic Scholar
JSH Guidelines for the Management of Hepatitis C Virus Infection: A 2016 update for genotype 1 and 2
Y. Asahina, N. Izumi, H. Kumada, M. Kurosaki +10 more
2016Hepatology Research85 citations
Semantic Scholar
Hepatolithiasis: analysis of Japanese nationwide surveys over a period of 40 years
Yutaka Suzuki, Toshiyuki Mori, M. Yokoyama, Tetsuya Nakazato +4 more
2014Journal of hepato-biliary-pancreatic sciences83 citations
Semantic Scholar
Nationwide survey for acute liver failure and late-onset hepatic failure in Japan
Masamitsu Nakao, N. Nakayama, Yoshihito Uchida, T. Tomiya +11 more
2018Journal of gastroenterology71 citations
Semantic Scholar
HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression
Nao Nishikoba, K. Kumagai, S. Kanmura, Yuko C. Nakamura +9 more
2020Frontiers in Immunology69 citations Open access
Semantic Scholar
Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice
K. Kumagai, Kazuaki Tabu, F. Sasaki, Yoichiro Takami +10 more
2015PLoS ONE65 citations Open access
Semantic Scholar
Pathological diagnosis of flat epithelial lesions of the biliary tract with emphasis on biliary intraepithelial neoplasia
Yasunori Sato, M. Sasaki, K. Harada, S. Aishima +7 more
2013Journal of gastroenterology60 citations
Semantic Scholar
Simeprevir (TMC435) once daily with peginterferon‐α‐2b and ribavirin in patients with genotype 1 hepatitis C virus infection: The CONCERTO‐4 study
H. Kumada, N. Hayashi, N. Izumi, T. Okanoue +7 more
2015Hepatology Research56 citations
Semantic Scholar
Transgenic expression of human neutrophil peptide‐1 enhances hepatic fibrosis in mice fed a choline‐deficient, L‐amino acid–defined diet
R. Ibusuki, H. Uto, S. Arima, Seiichi Mawatari +9 more
2013Liver international (Print)54 citations
Semantic Scholar
Growth factor-eluting cochlear implant electrode: impact on residual auditory function, insertional trauma, and fibrosis
Y. Kikkawa, T. Nakagawa, Lin Ying, Y. Tabata +3 more
2014Journal of Translational Medicine52 citations Open access
Semantic Scholar
Autoantibody status and histological variables influence biochemical response to treatment and long‐term outcomes in Japanese patients with primary biliary cirrhosis
Minoru Nakamura, H. Kondo, A. Tanaka, A. Komori +22 more
2015Hepatology Research51 citations
Semantic Scholar
Effect of Endoscopic Submucosal Dissection for Superficial Esophageal Neoplasms and Risk Factors for Postoperative Stricture
K. Funakawa, H. Uto, F. Sasaki, Yuichiro Nasu +10 more
2015Medicine48 citations Open access
Semantic Scholar
Biochemical responses to bezafibrate improve long-term outcome in asymptomatic patients with primary biliary cirrhosis refractory to UDCA
A. Tanaka, J. Hirohara, Y. Nakanuma, H. Tsubouchi +1 more
2015Journal of gastroenterology47 citations Open access
Semantic Scholar
Autoimmune hepatitis: Diagnosis and treatment guide in Japan, 2013
M. Onji, M. Zeniya, Kazuhide Yamamoto, H. Tsubouchi
2014Hepatology Research43 citations
Semantic Scholar
Hypertension exacerbates liver injury and hepatic fibrosis induced by a choline-deficient L-amino acid-defined diet in rats.
S. Arima, H. Uto, R. Ibusuki, R. Kumamoto +8 more
2014International Journal of Molecular Medicine40 citations Open access
Semantic Scholar
Nationwide prospective and retrospective surveys for hepatitis B virus reactivation during immunosuppressive therapies
S. Mochida, Masamitsu Nakao, N. Nakayama, Yoshihito Uchida +21 more
2016Journal of gastroenterology36 citations
Semantic Scholar
Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C
Kumiko Mera, H. Uto, Seiichi Mawatari, A. Ido +12 more
2014BMC Gastroenterology35 citations Open access
Semantic Scholar
Dietary fructose enhances the incidence of precancerous hepatocytes induced by administration of diethylnitrosamine in rat
R. Kumamoto, H. Uto, Kohei Oda, R. Ibusuki +11 more
2013European Journal of Medical Research34 citations Open access
Semantic Scholar
Preoperative classification of submucosal fibrosis in colorectal laterally spreading tumors by endoscopic ultrasonography
Tomoaki Makino, S. Kanmura, F. Sasaki, Yuichiro Nasu +10 more
2015Endoscopy International Open31 citations Open access
Semantic Scholar
Classification of the etiologies of acute liver failure in Japan: A report by the Intractable Hepato‐Biliary Diseases Study Group of Japan
S. Mochida, Y. Takikawa, N. Nakayama, M. Oketani +5 more
2014Hepatology Research31 citations Open access
Semantic Scholar
Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel electrophoresis
Y. Ishida, M. Yamasaki, Chizuko Yukizaki, Kazuo Nishiyama +3 more
2014Human Cell30 citations
Semantic Scholar
A Model to Predict 1‐Month Risk of Transplant or Death in Hepatitis A–Related Acute Liver Failure
Jin Dong Kim, E. Cho, Choonghyun Ahn, S. K. Park +29 more
2019Hepatology29 citations Open access
Semantic Scholar
Expression of glycoprotein nonmetastatic melanoma protein B in macrophages infiltrating injured mucosa is associated with the severity of experimental colitis in mice.
F. Sasaki, K. Kumagai, H. Uto, Yoichiro Takami +10 more
2015Molecular Medicine Reports29 citations Open access
Semantic Scholar
Management of hepatitis B virus-related acute liver failure
M. Oketani, H. Uto, A. Ido, H. Tsubouchi
2014Clinical Journal of Gastroenterology28 citations Open access
Semantic Scholar
Clinical profiles of patients with primary sclerosing cholangitis in the elderly
A. Tanaka, S. Tazuma, K. Okazaki, H. Tsubouchi +2 more
2015Journal of hepato-biliary-pancreatic sciences24 citations Open access
Semantic Scholar
Effect of dietary blueberry (Vaccinium ashei Reade) leaves on serum and hepatic lipid levels in rats.
Kumiko Yuji, H. Sakaida, T. Kai, N. Fukuda +4 more
2013Journal of Oleo Science23 citations Open access
Semantic Scholar
Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways.
Kazunari Ibusuki, T. Sakiyama, S. Kanmura, Takuro Maeda +9 more
2015International Journal of Molecular Medicine22 citations Open access
Semantic Scholar
Human neutrophil peptide-1 promotes alcohol-induced hepatic fibrosis and hepatocyte apoptosis
R. Ibusuki, H. Uto, Kohei Oda, Akihiko Ohshige +8 more
2017PLoS ONE20 citations Open access
Semantic Scholar
Phase 1 study on the safety and efficacy of E6011, antifractalkine antibody, in patients with Crohn's disease
K. Matsuoka, M. Naganuma, T. Hibi, H. Tsubouchi +7 more
2021Journal of Gastroenterology and Hepatology19 citations Open access
Semantic Scholar
Hepatocyte Growth Factor Facilitates Esophageal Mucosal Repair and Inhibits the Submucosal Fibrosis in a Rat Model of Esophageal Ulcer
Y. Komaki, S. Kanmura, F. Sasaki, H. Maeda +8 more
2018Digestion19 citations
Semantic Scholar
Multicenter validation study of anti‐programmed cell death‐1 antibody as a serological marker for type 1 autoimmune hepatitis
Y. Miyake, Kazuhide Yamamoto, H. Matsushita, M. Abe +13 more
2014Hepatology Research19 citations
Semantic Scholar
Hepatic expression of the Sptlc3 subunit of serine palmitoyltransferase is associated with the development of hepatocellular carcinoma in a mouse model of nonalcoholic steatohepatitis.
Yozo Yoshimine, H. Uto, K. Kumagai, Seiichi Mawatari +10 more
2015Oncology Report18 citations Open access
Semantic Scholar
Increasing prevalence of diabetes mellitus in association with fatty liver in a Japanese population
Yasushi Imamura, H. Uto, Yasunari Hiramine, Kaori Hosoyamada +7 more
2014Journal of gastroenterology18 citations
Semantic Scholar
Influence of human T-lymphotropic virus type 1 coinfection on the development of hepatocellular carcinoma in patients with hepatitis C virus infection
M. Tokunaga, H. Uto, Kohei Oda, M. Tokunaga +8 more
2014Journal of gastroenterology18 citations
Semantic Scholar
Hepatocyte growth factor stimulates the migration of gastric epithelial cells by altering the subcellular localization of the tight junction protein ZO-1
Yuichiro Nasu, A. Ido, S. Tanoue, S. Hashimoto +11 more
2013Journal of gastroenterology18 citations
Semantic Scholar
Anti-Apoptotic Effects of Recombinant Human Hepatocyte Growth Factor on Hepatocytes Were Associated with Intrahepatic Hemorrhage Suppression Indicated by the Preservation of Prothrombin Time
Sotaro Motoi, H. Toyoda, T. Obara, Etsuko Ohta +9 more
2019International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Effects of a fish-based diet and administration of pure eicosapentaenoic acid on brachial-ankle pulse wave velocity in patients with cardiovascular risk factors.
Y. Fukuoka, N. Nuruki, S. Amiya, Katsunori Tofuku +2 more
2014Journal of Cardiology16 citations Open access
Semantic Scholar
A case of hereditary hemorrhagic telangiectasia with repeated hemobilia arrested by argon plasma coagulation under direct peroral cholangioscopy.
Y. Komaki, S. Kanmura, K. Funakawa, F. Komaki +7 more
2014Gastrointestinal Endoscopy16 citations
Semantic Scholar
Endoscopic ultrasonography-guided transmural drainage of an infected hepatic cyst due to Edwardsiella tarda: a case report
Hiroki Taguchi, T. Tamai, Masatsugu Numata, Hitomi Maeda +8 more
2014Clinical Journal of Gastroenterology15 citations
Semantic Scholar
Multicenter Study of Pegylated Interferon α‐2a Monotherapy for Hepatitis C Virus‐Infected Patients on Hemodialysis: REACH Study
K. Kikuchi, T. Akiba, K. Nitta, I. Masakane +24 more
2014Therapeutic apheresis and dialysis15 citations
Semantic Scholar
Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4
Seiichi Mawatari, H. Uto, A. Ido, K. Nakashima +12 more
2013PLoS ONE15 citations Open access
Semantic Scholar
Deteriorated outcome of recent patients with acute liver failure and late‐onset hepatic failure caused by infection with hepatitis A virus: A subanalysis of patients seen between 1998 and 2015 and enrolled in nationwide surveys in Japan
Masamitsu Nakao, N. Nakayama, Yoshihito Uchida, T. Tomiya +5 more
2019Hepatology Research13 citations
Semantic Scholar
Low concentrations of human neutrophil peptide ameliorate experimental murine colitis
Takuro Maeda, T. Sakiyama, S. Kanmura, S. Hashimoto +11 more
2016International Journal of Molecular Medicine13 citations Open access
Semantic Scholar
Antihypertensive therapy improves insulin resistance and serum levels of interleukin-6 and -10 in spontaneously hypertensive rats with steatohepatitis.
M. Kozono, H. Uto, R. Ibusuki, S. Arima +10 more
2016Molecular Medicine Reports13 citations Open access
Semantic Scholar

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A. Ido×28
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A. Ido — researcher profile on SciRah
H. Uto×21
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H. Uto — researcher profile on SciRah
S. Kanmura×16
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S. Kanmura — researcher profile on SciRah
S. Hashimoto×13
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S. Hashimoto — researcher profile on SciRah

Seiichi Mawatari

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Seiichi Mawatari — researcher profile on SciRah

Masatsugu Numata×12

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Masatsugu Numata — researcher profile on SciRah

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M. Oketani — researcher profile on SciRah

H. Takikawa×10

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H. Takikawa — researcher profile on SciRah

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K. Kumagai — researcher profile on SciRah

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Kohei Oda — researcher profile on SciRah

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F. Sasaki — researcher profile on SciRah

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S. Arima — researcher profile on SciRah