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Diana Fontinha · SciRah

Researcher profile · Semantic Scholar

Diana Fontinha

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Diana Fontinha — researcher profile on SciRah

h-index: 17
Works: 67
Citations: 765

Most-cited papers

Effector γδ T Cell Differentiation Relies on Master but Not Auxiliary Th Cell Transcription Factors
Joana Barros-Martins, N. Schmolka, Diana Fontinha, Marta Pires de Miranda +6 more
2016Journal of Immunology66 citations Open access
Semantic Scholar
Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development
C. S. Cunha, Britta Nyboer, K. Heiss, Margarida Sanches-Vaz +7 more
2017Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Alkaloids from Narcissus poeticus cv. Pink Parasol of various structural types and their biological activity
M. Safratova, A. Hošťálková, D. Hulcová, K. Breiterová +13 more
2017Archives of pharmacal research39 citations
Semantic Scholar
Primaquine hybrids as promising antimycobacterial and antimalarial agents.
Kristina Pavić, Ivana Perković, Š. Pospíšilová, Marta Machado +7 more
2018European journal of medicinal chemistry34 citations
Semantic Scholar
Harmicines - harmine and cinnamic acid hybrids as novel antiplasmodial hits.
Ivana Perković, S. Raić-Malić, Diana Fontinha, M. Prudêncio +6 more
2019European journal of medicinal chemistry33 citations
Semantic Scholar
Flexible 3D cell-based platforms for the discovery and profiling of novel drugs targeting Plasmodium hepatic infection.
F. Arez, Sofia P. Rebelo, Diana Fontinha, D. Simão +12 more
2019ACS Infectious Diseases32 citations Open access
Semantic Scholar
Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and Plasmodium.
Nuno G. Alves, Inês Bártolo, Américo J. S. Alves, Diana Fontinha +7 more
2021European journal of medicinal chemistry23 citations Open access
Semantic Scholar
Gold(iii) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents.
Diana Fontinha, S. Sousa, Tânia S. Morais, M. Prudêncio +10 more
2020Metallomics23 citations
Semantic Scholar
On the path to gold: Monoanionic Au bisdithiolate complexes with antimicrobial and antitumor activities.
S. Sousa, J. Leitão, Rafaela A. L. Silva, D. Belo +8 more
2019Journal of Inorganic Biochemistry23 citations
Semantic Scholar
Spiro-Lactams as Novel Antimicrobial Agents.
Américo J. S. Alves, Nuno G. Alves, Cátia C. Caratão, Margarida I M Esteves +7 more
2019Current Topics in Medicinal Chemistry22 citations Open access
Semantic Scholar
Molecular Design and Synthesis of Ivermectin Hybrids Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites.
Lovepreet Singh, Diana Fontinha, Denise Francisco, A. Mendes +2 more
2020Journal of Medicinal Chemistry21 citations Open access
Semantic Scholar
Further investigation of harmicines as novel antiplasmodial agents: Synthesis, structure-activity relationship and insight into the mechanism of action.
M. Marinović, Goran Poje, Ivana Perković, Diana Fontinha +6 more
2021European journal of medicinal chemistry20 citations
Semantic Scholar
A Novel Hybrid of Chloroquine and Primaquine Linked by Gold(I): Multitarget and Multiphase Antiplasmodial Agent
Caroline Souza Pereira, Helenita Costa Quadros, Diogo Rodrigo Magalhaes Moreira, William Castro +11 more
2020ChemMedChem20 citations
Semantic Scholar
Repurposing Drugs to Fight Hepatic Malaria Parasites
Diana Fontinha, Isabel Moules, M. Prudêncio
2020Molecules20 citations Open access
Semantic Scholar
Establishment of Murine Gammaherpesvirus Latency in B Cells Is Not a Stochastic Event
J. Decalf, Cristina Godinho-Silva, Diana Fontinha, Sofia Marques +1 more
2014PLoS Pathogens20 citations Open access
Semantic Scholar
Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action.
Malkeet Kumar, John Okombo, Dickson Mambwe, D. Taylor +14 more
2018ACS Infectious Diseases18 citations Open access
Semantic Scholar
Spiro-β-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium.
Inês Bártolo, Bruna S. Santos, Diana Fontinha, Marta Machado +15 more
2021ACS Infectious Diseases17 citations Open access
Semantic Scholar
Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle
H. Quadros, Aysun Çapcı, Lars Herrmann, S. D'Alessandro +7 more
2021Pharmaceuticals15 citations Open access
Semantic Scholar
Novel Harmicines with Improved Potency against Plasmodium
M. Marinović, Ivana Perković, Diana Fontinha, M. Prudêncio +6 more
2020Molecules15 citations Open access
Semantic Scholar
Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity.
Elizabeth A. Lopes, R. Mestre, Diana Fontinha, J. Legac +7 more
2022European journal of medicinal chemistry14 citations Open access
Semantic Scholar
Pre-erythrocytic Activity of M5717 in Monotherapy and Combination in Preclinical Plasmodium Infection Models
Diana Fontinha, F. Arez, Isabella Ramella Gal, G. Nogueira +6 more
2022ACS Infectious Diseases14 citations Open access
Semantic Scholar
Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity
T. A. Tavella, Noeli Soares Melo da Silva, Natalie J. Spillman, A. C. K. Kayano +22 more
2021ACS Infectious Diseases14 citations Open access
Semantic Scholar
SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents
M. Beus, Z. Rajić, D. Maysinger, Z. Mlinarić +7 more
2018ChemistryOpen14 citations Open access
Semantic Scholar
A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-Toxoplasma and Anti-Plasmodium Activities Controls Acute and Chronic Toxoplasma Infection in Mice
D. Jublot, P. Cavaillès, Salima Kamche, Denise Francisco +6 more
2022International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis
Caroline de Souza Pereira, H. Quadros, S. Y. Aboagye, Diana Fontinha +11 more
2022Pharmaceutics13 citations Open access
Semantic Scholar
Novel Antiplasmodial Compounds Leveraged with Multistage Potency against the Parasite Plasmodium falciparum: In Vitro and In Vivo Evaluations and Pharmacokinetic Studies.
N. Sharma, M. Kashif, Vigyasa Singh, Diana Fontinha +6 more
2021Journal of Medicinal Chemistry13 citations
Semantic Scholar
Primaquine and Chloroquine Fumardiamides as Promising Antiplasmodial Agents
M. Beus, Diana Fontinha, Jana Held, Z. Rajić +4 more
2019Molecules13 citations Open access
Semantic Scholar
Discovery of harmiprims, harmine-primaquine hybrids, as potent and selective anticancer and antimalarial compounds.
Kristina Pavić, Goran Poje, Lais Pessanha de Carvalho, Tana Tandarić +9 more
2024Bioorganic & Medicinal Chemistry12 citations
Semantic Scholar
4,9‐Diaminoacridines and 4‐Aminoacridines as Dual‐Stage Antiplasmodial Hits
Mélanie Fonte, Natália Tassi, Diana Fontinha, Inés Bouzón-Arnáiz +6 more
2020ChemMedChem10 citations Open access
Semantic Scholar
Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria.
G. Mayoka, Mathew Njoroge, John Okombo, Liezl Gibhard +14 more
2019Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants
L. T. Ferreira, G. C. Cassiano, L. C. S. Alvarez, John Okombo +13 more
2024PLoS Pathogens9 citations Open access
Semantic Scholar
Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside
Akash Khandelwal, F. Arez, P. Alves, L. Badolo +10 more
2022Malaria Journal9 citations Open access
Semantic Scholar
Synthesis and antiplasmodial activity of regioisomers and epimers of second-generation dual acting ivermectin hybrids
Lovepreet Singh, Diana Fontinha, Denise Francisco, M. Prudêncio +1 more
2022Scientific Reports9 citations Open access
Semantic Scholar
Half-Sandwich Cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype.
S. A. Milheiro, Joana Gonçalves, Ricardo M. R. M. Lopes, M. Madureira +9 more
2020Inorganic Chemistry8 citations Open access
Semantic Scholar
Broad Spectrum Functional Activity of Structurally Related Monoanionic Au(III) Bis(Dithiolene) Complexes
Y. le Gal, Agathe Filatre-Furcate, D. Lorcy, O. Jeannin +14 more
2022International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Unveiling a family of spiro-β-lactams with anti-HIV and antiplasmodial activity via phosphine-catalyzed [3+2] annulation of 6-alkylidene-penicillanates and allenoates
Américo J. S. Alves, Nuno G. Alves, Inês Bártolo, Diana Fontinha +4 more
2022Frontiers in Chemistry7 citations Open access
Semantic Scholar
Synthesis of the new analogs of morpholine and their antiplasmodial evaluation against the human malaria parasite Plasmodium falciparum
Charu Upadhyay, Neha Sharma, Sumit Kumar, P. Sharma +7 more
2021New Journal of Chemistry7 citations
Semantic Scholar
Synthesis and antiplasmodial evaluation of novel mefloquine-based fumardiamides
M. Beus, Diana Fontinha, Jana Held, Z. Rajić +2 more
2019Acta Pharmaceutica7 citations Open access
Semantic Scholar
Drug‐Derived Surface‐Active Ionic Liquids: A Cost‐Effective Way To Expressively Increase the Blood‐Stage Antimalarial Activity of Primaquine
Ana Teresa Silva, I. Oliveira, Joana Gomes, Luísa Aguiar +8 more
2021ChemMedChem6 citations Open access
Semantic Scholar
Elimination of Hepatic Rodent Plasmodium Parasites by Amino Acid Supplementation
P. Meireles, Daniela Brás, Diana Fontinha, Â. Chora +3 more
2020iScience6 citations Open access
Semantic Scholar
A crucial role for the C‐terminal domain of exported protein 1 during the mosquito and hepatic stages of the Plasmodium berghei life cycle
Kamila Wolanin, Diana Fontinha, Margarida Sanches-Vaz, Britta Nyboer +3 more
2019Cellular Microbiology6 citations Open access
Semantic Scholar
Drug Interaction Studies of Cabamiquine:Ganaplacide Combination against Hepatic Plasmodium berghei
Isabella Ramella Gal, Claudia Demarta-Gatsi, Diana Fontinha, F. Arez +10 more
2024ACS Infectious Diseases5 citations Open access
Semantic Scholar
Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro
K. Breiterová, A. Ritomská, Diana Fontinha, J. Křoustková +9 more
2023Pharmaceutics4 citations Open access
Semantic Scholar
New 4-(N-cinnamoylbutyl)aminoacridines as potential multi-stage antiplasmodial leads.
Mélanie Fonte, Diana Fontinha, Diana Moita, Omar Caño-Prades +5 more
2023European journal of medicinal chemistry4 citations Open access
Semantic Scholar
Primaquine homodimers as potential antiplasmodial and anticancer agents.
Kristina Pavić, Barbara Rubinić, Z. Rajić, Diana Fontinha +5 more
2019Bioorganic & Medicinal Chemistry Letters4 citations
Semantic Scholar
Defining Immune Engagement Thresholds for In Vivo Control of Virus-Driven Lymphoproliferation
Cristina Godinho-Silva, Sofia Marques, Diana Fontinha, H. Veiga-Fernandes +2 more
2014PLoS Pathogens4 citations Open access
Semantic Scholar
Antiplasmodial and Insecticidal Activities of Third-Generation Ivermectin Hybrids
Parth, S. Santana, C. Rôla, C. B. Oliveira +3 more
2024Journal of Medicinal Chemistry3 citations Open access
Semantic Scholar
Unexpected rearrangement of ivermectin in the synthesis of new derivatives with trypanocidal and antiplasmodial activities.
Michał Sulik, Diana Fontinha, Dietmar Steverding, S. Sobczak +3 more
2023European journal of medicinal chemistry3 citations Open access
Semantic Scholar
Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside
Akash Khandelwal, F. Arez, P. Alves, L. Badolo +10 more
2022Malaria Journal3 citations Open access
Semantic Scholar
Facile Access to Structurally Diverse Antimalarial Indoles Using a One‐Pot A3 Coupling and Domino Cyclization Approach
Gustavo Cossio da Silva, André Luz, Denise Duarte, Diana Fontinha +8 more
2023ChemMedChem2 citations Open access
Semantic Scholar

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