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Katherine R. Singleton · SciRah

Researcher profile · Semantic Scholar

Katherine R. Singleton

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Katherine R. Singleton — researcher profile on SciRah

h-index: 11
Works: 23
Citations: 708

Most-cited papers

Systematic identification of signaling pathways with potential to confer anticancer drug resistance
Colin A. Martz, K. Ottina, Katherine R. Singleton, Jeff S. Jasper +16 more
2014Science Signaling191 citations Open access
Semantic Scholar
Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells
Marianne E. Marshall, T. Hinz, S. Kono, Katherine R. Singleton +6 more
2011Clinical Cancer Research108 citations Open access
Semantic Scholar
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence
Katherine R. Singleton, L. Crawford, E. Tsui, Haley E Manchester +18 more
2017Cell Reports104 citations Open access
Semantic Scholar
Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC
Katherine R. Singleton, T. Hinz, E. Kleczko, Lindsay A. Marek +5 more
2015Cancer Research60 citations Open access
Semantic Scholar
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
Kevin H. Lin, Justine C. Rutter, Abigail Xie, Bryann Pardieu +15 more
2020Nature Genetics58 citations Open access
Semantic Scholar
A Receptor Tyrosine Kinase Network Composed of Fibroblast Growth Factor Receptors, Epidermal Growth Factor Receptor, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, and Hepatocyte Growth Factor Receptor Drives Growth and Survival of Head and Neck Squamous Carcinoma Cell Lines
Katherine R. Singleton, Jihye Kim, T. Hinz, Lindsay A. Marek +5 more
2013Molecular Pharmacology38 citations Open access
Semantic Scholar
Elevated extracellular K+ inhibits apoptosis of corneal epithelial cells exposed to UV-B radiation.
Katherine R. Singleton, D. Will, Mark P. Schotanus, Loren D. Haarsma +3 more
2008Experimental Eye Research30 citations
Semantic Scholar
Drug dependence in cancer is exploitable by optimally constructed treatment holidays
Jeff Maltas, Shane T. Killarney, Katherine R. Singleton, Maximillian Strobl +3 more
2022bioRxiv27 citations Open access
Semantic Scholar
Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy
Jihye Kim, V. Vasu, Rangnath Mishra, Katherine R. Singleton +10 more
2014Bioinform.26 citations Open access
Semantic Scholar
ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer
Amanda Pilling, Jihye Kim, A. Estrada-Bernal, Qiong Zhou +6 more
2018OncoTarget25 citations Open access
Semantic Scholar
Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis
Maria Liberti, Annamarie E. Allen, Vijyendra Ramesh, Ziwei Dai +5 more
2019Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes
Katherine R. Singleton, K. Wood
2016Genes & cancer7 citations Open access
Semantic Scholar
An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases
E. Kleczko, Jihye Kim, S. Keysar, Lydia R. Heasley +7 more
2015PLoS ONE6 citations Open access
Semantic Scholar
Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines
T. Hinz, E. Kleczko, Katherine R. Singleton, Jacob Calhoun +4 more
2019Molecular Pharmacology5 citations Open access
Semantic Scholar
Analysis of Drug Resistance Using Kinome-Wide Functional Screens.
Katherine R. Singleton, Keith T. Earley, L. Heasley
2017Methods in molecular biology2 citations
Semantic Scholar
EGFR inhibitor-resistant lung cancers exhibit collateral sensitivity to a covalent, cysteine-independent KEAP1 oligomerizing molecular bridge
C. F. Bassil, Kerry Dillon, Gray R. Anderson, Benjamin Mayro +27 more
2026Nature Communications1 citations Open access
Semantic Scholar
Evolved resistance to GAPDH inhibition results in loss of the Warburg Effect but retains a different state of glycolysis
Maria Liberti, Annamarie E. Allen, Vijyendra Ramesh, Ziwei Dai +5 more
2019bioRxiv1 citations Open access
Semantic Scholar
Abstract 5594: ALK-driven lung cancer: Potential therapeutic strategies for treatment and prevention of drug resistance
Amanda Pilling, A. Le, A. Tan, Jihye Kim +5 more
20121 citations
Semantic Scholar
MCB-613 exploits a collateral sensitivity in drug resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1
C. F. Bassil, Gray R. Anderson, Benjamin Mayro, Kayleigh N. Askin +19 more
2023bioRxiv0 citations Open access
Semantic Scholar
Author Correction: Drug dependence in cancer is exploitable by optimally constructed treatment holidays
Jeff Maltas, Shane T. Killarney, Katherine R. Singleton, Maximillian Strobl +3 more
2023Nature Ecology & Evolution0 citations Open access
Semantic Scholar
Abstract 3387: Tyrosine kinase inhibitors induce TGF-β2 expression in head and neck squamous cell carcinoma cell lines as a mechanism of acquired resistance.
E. Kleczko, Lydia R. Heasley, Marianne E. Marshall, Katherine R. Singleton +1 more
20130 citations
Semantic Scholar
Abstract B35: Alternate receptor tyrosine kinases provide protection from FGFR inhibition in HNSCC cells as identified by genome-wide shRNA screening
Katherine R. Singleton, A. Tan, Jihye Kim, L. Heasley
2012Clinical Cancer Research0 citations
Semantic Scholar
Cancer Therapy : Preclinical Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells
Marianne E. Marshall, T. Hinz, S. Kono, Katherine R. Singleton +6 more
20110 citations
Semantic Scholar

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Lindsay A. Marek×5

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Marianne E. Marshall×4

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Maria Liberti — researcher profile on SciRah