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Wen-Le Zhao · SciRah

Researcher profile · Semantic Scholar

Wen-Le Zhao

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Wen-Le Zhao — researcher profile on SciRah

h-index: 18
Works: 59
Citations: 1,826

Most-cited papers

Speed of response and remission in major depressive disorder with acute electroconvulsive therapy (ECT): a Consortium for Research in ECT (CORE) report.
M. Husain, A. Rush, M. Fink, R. Knapp +13 more
2004Journal of Clinical Psychiatry412 citations
Semantic Scholar
Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke: A Randomized Clinical Trial.
S. Cramer, L. Dodakian, Vu H. Le, J. See +23 more
2019JAMA Neurology351 citations Open access
Semantic Scholar
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial
J. Chamberlain, J. Kapur, S. Shinnar, Jordan Elm +231 more
2020The Lancet176 citations Open access
Semantic Scholar
Minimal sufficient balance—a new strategy to balance baseline covariates and preserve randomness of treatment allocation
Wen-Le Zhao, M. Hill, Y. Palesch
2012Statistical Methods in Medical Research83 citations Open access
Semantic Scholar
Block urn design - a new randomization algorithm for sequential trials with two or more treatments and balanced or unbalanced allocation
Wen-Le Zhao, Yanqiu Weng
2011Contemporary Clinical Trials71 citations Open access
Semantic Scholar
Quantitative comparison of randomization designs in sequential clinical trials based on treatment balance and allocation randomness
Wen-Le Zhao, Yanqiu Weng, Qi Wu, Y. Palesch
2011Pharmaceutical statistics57 citations Open access
Semantic Scholar
An Overview of the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Project
W. Meurer, R. Lewis, D. Tagle, M. Fetters +11 more
2012Annals of Emergency Medicine47 citations Open access
Semantic Scholar
A better alternative to stratified permuted block design for subject randomization in clinical trials
Wen-Le Zhao
2014Statistics in Medicine45 citations Open access
Semantic Scholar
Two Pharmacy Interventions to Improve Refill Persistence for Chronic Disease Medications: A Randomized, Controlled Trial
P. Nietert, B. Tilley, Wen-Le Zhao, Peter F Edwards +3 more
2009Medical Care39 citations
Semantic Scholar
Measuring continuous baseline covariate imbalances in clinical trial data
J. Ciolino, Renee' H. Martin, Wen-Le Zhao, M. Hill +2 more
2011Statistical Methods in Medical Research35 citations Open access
Semantic Scholar
Quantifying the cost in power of ignoring continuous covariate imbalances in clinical trial randomization
J. Ciolino, Wen-Le Zhao, Renee L Martin, Y. Palesch
2010Contemporary Clinical Trials35 citations Open access
Semantic Scholar
The asymptotic maximal procedure for subject randomization in clinical trials
Wen-Le Zhao, V. Berger, Zhenning Yu
2018Statistical Methods in Medical Research29 citations
Semantic Scholar
Imaging in StrokeNet: Realizing the Potential of Big Data
D. Liebeskind, G. Albers, K. Crawford, C. Derdeyn +13 more
2015Stroke28 citations Open access
Semantic Scholar
Covariate Imbalance and Adjustment for Logistic Regression Analysis of Clinical Trial Data
J. Ciolino, Renee' H. Martin, Wen-Le Zhao, E. Jauch +2 more
2013Journal of Biopharmaceutical Statistics28 citations Open access
Semantic Scholar
Mass weighted urn design - a new randomization algorithm for unequal allocations
Wen-Le Zhao
2015Contemporary Clinical Trials27 citations Open access
Semantic Scholar
Prevalence, treatment, and control of hypertension among African Americans and Caucasians at primary care sites for medically under-served patients.
N. Sheats, Yan Lin, Wen-Le Zhao, D. Cheek +2 more
2005Ethnicity & Disease25 citations
Semantic Scholar
Selection bias, allocation concealment and randomization design in clinical trials.
Wen-Le Zhao
2013Contemporary Clinical Trials22 citations
Semantic Scholar
A Comprehensive View of Frequent Emergency Department Users Based on Data from a Regional HIE
S. Saef, Christine M. Carr, J. Bush, M. Bartman +11 more
2016Southern medical journal (Birmingham, Ala. Print)19 citations Open access
Semantic Scholar
Intense Arm Rehabilitation Therapy Improves the Modified Rankin Scale Score: Association Between Gains in Impairment and Function.
S. Cramer, Vu H. Le, J. Saver, L. Dodakian +24 more
2021Neurology18 citations Open access
Semantic Scholar
Flexible Analytical methods for Adding a Treatment Arm Mid-study to an Ongoing Clinical Trial
J. Elm, Y. Palesch, G. Koch, V. Hinson +2 more
2012Journal of Biopharmaceutical Statistics18 citations Open access
Semantic Scholar
Imbalance control in clinical trial subject randomization-from philosophy to strategy.
Wen-Le Zhao, V. Berger
2018Journal of Clinical Epidemiology17 citations
Semantic Scholar
Step-forward randomization in multicenter emergency treatment clinical trials
Wen-Le Zhao, J. Ciolino, Y. Palesch
2010Academic Emergency Medicine17 citations Open access
Semantic Scholar
Continuous Covariate Imbalance and Conditional Power for Clinical Trial Interim Analyses
J. Ciolino, Renee' H. Martin, Wen-Le Zhao, E. Jauch +2 more
2014Contemporary Clinical Trials16 citations Open access
Semantic Scholar
National Institutes of Health StrokeNet During the Time of COVID-19 and Beyond
J. Broderick, Jordan Elm, L. Janis, Wen-Le Zhao +34 more
2020Stroke15 citations Open access
Semantic Scholar
Time-trend impact on treatment estimation in two-arm clinical trials with a binary outcome and Bayesian response adaptive randomization
Yun-Yun Jiang, Wen-Le Zhao, V. Durkalski‐Mauldin
2019Journal of Biopharmaceutical Statistics15 citations Open access
Semantic Scholar
Text mining approach to evaluate terms for ontology development
L. Tsoi, Ravi Patel, Wen-Le Zhao, W. Zheng
2009Journal of Biomedical Informatics15 citations Open access
Semantic Scholar
Impact of adaptation algorithm, timing, and stopping boundaries on the performance of Bayesian response adaptive randomization in confirmative trials with a binary endpoint.
Yun-Yun Jiang, Wen-Le Zhao, V. Durkalski‐Mauldin
2017Contemporary Clinical Trials14 citations
Semantic Scholar
A simplified formula for quantification of the probability of deterministic assignments in permuted block randomization
Wen-Le Zhao, Yanqiu Weng
2011Journal of Statistical Planning and Inference14 citations Open access
Semantic Scholar
Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
M. Farrant, J. D. Easton, E. Adelman, B. Cucchiara +12 more
2019JAMA Network Open12 citations Open access
Semantic Scholar
The Impact of Covariate Adjustment at Randomization and Analysis For Binary Outcomes: Understanding Differences Between Superiority and Non-Inferiority Trials
Katherine S. Nicholas, S. Yeatts, Wen-Le Zhao, J. Ciolino +2 more
2015Statistics in Medicine12 citations Open access
Semantic Scholar
Architecture design of a generic centralized adjudication module integrated in a web-based clinical trial management system
Wen-Le Zhao, Keith Pauls
2015Clinical Trials11 citations Open access
Semantic Scholar
Statistical properties of minimal sufficient balance and minimization as methods for controlling baseline covariate imbalance at the design stage of sequential clinical trials
S. Lauzon, V. Ramakrishnan, P. Nietert, J. Ciolino +2 more
2020Statistics in Medicine10 citations Open access
Semantic Scholar
Guessing strategies for treatment prediction under restricted randomization with unequal allocation.
Wen-Le Zhao, C. Everett, Yanqiu Weng, V. Berger
2017Contemporary Clinical Trials9 citations Open access
Semantic Scholar
A surrogate-primary replacement algorithm for response-adaptive randomization in stroke clinical trials
A. Nowacki, Wen-Le Zhao, Y. Palesch
2015Statistical Methods in Medical Research9 citations Open access
Semantic Scholar
A web-based medical safety reporting system for a large multicenter clinical trial - The ALIAS experience
Wen-Le Zhao, Bonnie D. Waldman, Catherine R. Dillon, Keith Pauls +5 more
2010Contemporary Clinical Trials9 citations Open access
Semantic Scholar
An Electronic Regulatory Document Management System for a Clinical Trial Network
Wen-Le Zhao, V. Durkalski, Keith Pauls, Catherine R. Dillon +5 more
2009Contemporary Clinical Trials9 citations Open access
Semantic Scholar
Impact of minimal sufficient balance, minimization, and stratified permuted blocks on bias and power in the estimation of treatment effect in sequential clinical trials with a binary endpoint
S. Lauzon, Wen-Le Zhao, P. Nietert, J. Ciolino +2 more
2021Statistical Methods in Medical Research7 citations Open access
Semantic Scholar
A better alternative to the inferior permuted block design is not necessarily complex
Wen-Le Zhao
2016Statistics in Medicine7 citations
Semantic Scholar
Rationale and Study Design for a Single-Arm Phase IIa Study Investigating Feasibility of Preventing Ischemic Cerebrovascular Events in High-Risk Patients with Acute Non-disabling Ischemic Cerebrovascular Events Using Remote Ischemic Conditioning
Shi-Meng Liu, Wen-Le Zhao, Hai-qing Song, R. Meng +5 more
2018Chinese Medical Journal6 citations Open access
Semantic Scholar
Better alternatives to permuted block randomization for clinical trials with unequal allocation
Wen-Le Zhao, V. Berger
2017Hematology6 citations Open access
Semantic Scholar
Managing competing demands in the implementation of response-adaptive randomization in a large multi-center phase III acute stroke trial
Wen-Le Zhao, V. Durkalski
2014Statistics in Medicine6 citations Open access
Semantic Scholar
Optimal Randomization Designs for Large Multicenter Clinical Trials — From the NIH StrokeNet Experience
Wen-Le Zhao, S. Yeatts, J. Broderick, M. Selim +8 more
2023Stroke5 citations Open access
Semantic Scholar
Preventing Ischemic Cerebrovascular Events in High-Risk Patients With Non-disabling Ischemic Cerebrovascular Events Using Remote Ischemic Conditioning: A Single-Arm Study
Shi-Meng Liu, Zong'en Gao, R. Meng, Hai-Qing Song +22 more
2021Frontiers in Neurology5 citations Open access
Semantic Scholar
Evolution of Restricted Randomization with Maximum Tolerated Imbalance
Wen-Le Zhao
20175 citations
Semantic Scholar
Generalization of Wei’s urn design to unequal allocations in sequential clinical trials
Wen-Le Zhao, V. Ramakrishnan
2016Contemporary Clinical Trials Communications5 citations Open access
Semantic Scholar
Comparison of statistical and operational properties of subject randomization procedures for large multicenter clinical trial treating medical emergencies
Wen-Le Zhao, Yunming Mu, D. Tayama, S. Yeatts
2015Contemporary Clinical Trials3 citations Open access
Semantic Scholar
Steady-state statistical properties and implementation of randomization designs with maximum tolerated imbalance restriction for two-arm equal allocation clinical trials
Wen-Le Zhao, Kerstine Carter, Oleksandr Sverdlov, Annika L Scheffold +3 more
2024Statistics in Medicine2 citations
Semantic Scholar
When Should ED Physicians Use an HIE? Predicting Presence of Patient Data in an HIE
Christine M. Carr, S. Saef, Jing-Wen Zhang, Ze-Min Su +9 more
2016Southern medical journal (Birmingham, Ala. Print)2 citations Open access
Semantic Scholar
Impact of safety monitoring on error probabilities of binary efficacy outcome analyses in large phase III group sequential trials
Yanqiu Weng, Wen-Le Zhao, Y. Palesch
2012Pharmaceutical statistics1 citations Open access
Semantic Scholar
Innovative and effective subject randomization methods
Wen-Le Zhao
20200 citations
Semantic Scholar

Frequent co-authors

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Y. Palesch×16
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Y. Palesch — researcher profile on SciRah
J. Ciolino×8
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J. Ciolino — researcher profile on SciRah
M. Hill×6
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M. Hill — researcher profile on SciRah
Catherine R. Dillon×5
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Catherine R. Dillon — researcher profile on SciRah

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Yanqiu Weng — researcher profile on SciRah

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V. Berger — researcher profile on SciRah

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Keith Pauls — researcher profile on SciRah

J. Broderick×4

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J. Broderick — researcher profile on SciRah

V. Durkalski×4

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V. Durkalski — researcher profile on SciRah

Renee' H. Martin×4

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Renee' H. Martin — researcher profile on SciRah

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S. Cramer — researcher profile on SciRah

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