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P. Jiang · SciRah

Researcher profile · Semantic Scholar

P. Jiang

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P. Jiang — researcher profile on SciRah

h-index: 56
Works: 114
Citations: 12K

Most-cited papers

Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
K. Sun, P. Jiang, K. A. Allen Chan, John Wong +16 more
2015Proceedings of the National Academy of Sciences of the United States of America710 citations Open access
Semantic Scholar
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
P. Jiang, Carol W. M. Chan, K. A. Allen Chan, Suk H. Cheng +9 more
2015Proceedings of the National Academy of Sciences of the United States of America669 citations Open access
Semantic Scholar
Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies
Y. M. Dennis Lo, D. S. C. Han, P. Jiang, R. Chiu
2021Science552 citations
Semantic Scholar
Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing.
K. A. Allen Chan, P. Jiang, Ya-Ma W. L. Zheng, Gary J. W. Liao +9 more
2013Clinical Chemistry477 citations
Semantic Scholar
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
K. A. Allen Chan, P. Jiang, Carol W. M. Chan, K. Sun +14 more
2013Proceedings of the National Academy of Sciences of the United States of America399 citations Open access
Semantic Scholar
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C. Muus, M. Luecken, G. Eraslan, L. Sikkema +110 more
2021Nature Medicine326 citations Open access
Semantic Scholar
Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics
Jason C. H. Tsang, Joaquim S. L. Vong, Lu Ji, Liona C. Poon +7 more
2017Proceedings of the National Academy of Sciences of the United States of America302 citations Open access
Semantic Scholar
The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics.
P. Jiang, Y. M. Dennis Lo
2016Trends in Genetics297 citations
Semantic Scholar
Plasma DNA end motif profiling as a fragmentomic marker in cancer, pregnancy and transplantation.
P. Jiang, K. Sun, Wen-Lei Peng, Suk H. Cheng +17 more
2020Cancer Discovery287 citations
Semantic Scholar
Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing
S. C. Yu, K. A. Allen Chan, Ya-Ma W. L. Zheng, P. Jiang +11 more
2014Proceedings of the National Academy of Sciences of the United States of America264 citations Open access
Semantic Scholar
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
C. Muus, M. Luecken, G. Eraslan, Avinash Waghray +100 more
2020bioRxiv255 citations Open access
Semantic Scholar
Noninvasive prenatal diagnosis of congenital adrenal hyperplasia using cell-free fetal DNA in maternal plasma.
Maria I. New, Yu K. Tong, Tony Yuen, P. Jiang +10 more
2014Journal of Clinical Endocrinology and Metabolism249 citations Open access
Semantic Scholar
High-resolution profiling of fetal DNA clearance from maternal plasma by massively parallel sequencing.
S. C. Yu, S. Lee, P. Jiang, Tak Y. Leung +3 more
2013Clinical Chemistry231 citations Open access
Semantic Scholar
Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
K. Sun, P. Jiang, Suk H. Cheng, Timothy H. T. Cheng +13 more
2019Genome Research230 citations Open access
Semantic Scholar
Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma
P. Jiang, K. Sun, Yu K. Tong, Suk H. Cheng +8 more
2018Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA
Lee Serpas, R. W. Chan, P. Jiang, Meng Ni +11 more
2018Proceedings of the National Academy of Sciences of the United States of America199 citations Open access
Semantic Scholar
Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends
K. A. Allen Chan, P. Jiang, K. Sun, Y. K. Cheng +7 more
2016Proceedings of the National Academy of Sciences of the United States of America172 citations Open access
Semantic Scholar
iSeeRNA: identification of long intergenic non-coding RNA transcripts from transcriptome sequencing data
K. Sun, Xiaona Chen, P. Jiang, Xiao-Feng Song +2 more
2013BMC Genomics172 citations Open access
Semantic Scholar
Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma
W. K. Jacky Lam, P. Jiang, K. A. Allen Chan, Suk H. Cheng +12 more
2018Proceedings of the National Academy of Sciences of the United States of America153 citations Open access
Semantic Scholar
Identification and characterization of extrachromosomal circular DNA in maternal plasma
S. Sin, P. Jiang, Jiaen Deng, Lu Ji +6 more
2020Proceedings of the National Academy of Sciences of the United States of America149 citations Open access
Semantic Scholar
Noninvasive prenatal methylomic analysis by genomewide bisulfite sequencing of maternal plasma DNA.
Fiona MF Lun, R. Chiu, K. Sun, Tak Y. Leung +4 more
2013Clinical Chemistry148 citations Open access
Semantic Scholar
The origin of highly elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer
A. Mattox, C. Douville, Yuxuan Wang, M. Popoli +19 more
2023Cancer Discovery140 citations Open access
Semantic Scholar
Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing
K. Sun, P. Jiang, Ada I. C. Wong, Y. Cheng +6 more
2018Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing
R. W. Chan, P. Jiang, X. Peng, Lai-Shan Tam +7 more
2014Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
IL-37 Ameliorating Allergic Inflammation in Atopic Dermatitis Through Regulating Microbiota and AMPK-mTOR Signaling Pathway-Modulated Autophagy Mechanism
Tianheng Hou, Xiao-Yu Sun, Jing Zhu, Kam-Lun Hon +6 more
2020Frontiers in Immunology111 citations Open access
Semantic Scholar
Genome-wide detection of cytosine methylation by single molecule real-time sequencing
O. Y. Olivia Tse, P. Jiang, Suk H. Cheng, Wen-Lei Peng +8 more
2021Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma
S. C. Yu, P. Jiang, Wen-Lei Peng, Suk H. Cheng +8 more
2021Proceedings of the National Academy of Sciences of the United States of America94 citations Open access
Semantic Scholar
Detection and characterization of jagged ends of double-stranded DNA in plasma
P. Jiang, Ting-Ting Xie, Spencer C. Ding, Ze Zhou +13 more
2020Genome Research93 citations Open access
Semantic Scholar
Universal Haplotype-Based Noninvasive Prenatal Testing for Single Gene Diseases.
Winnie W. I. Hui, P. Jiang, Yu K. Tong, Wing-Shan Lee +7 more
2017Clinical Chemistry91 citations
Semantic Scholar
Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing
T. Leung, James Z. Z. Qu, Gary J. W. Liao, P. Jiang +4 more
2013Prenatal Diagnosis88 citations
Semantic Scholar
Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs
Ze Zhou, Mary-Jane L. Ma, R. W. Chan, W. K. Jacky Lam +21 more
2023Proceedings of the National Academy of Sciences of the United States of America84 citations Open access
Semantic Scholar
Maternal plasma RNA sequencing for genome-wide transcriptomic profiling and identification of pregnancy-associated transcripts.
Nancy B. Y. Tsui, P. Jiang, Yuen-Fei Wong, T. Leung +4 more
2014Clinical Chemistry84 citations Open access
Semantic Scholar
Genomewide bisulfite sequencing reveals the origin and time-dependent fragmentation of urinary cfDNA.
Timothy H. T. Cheng, P. Jiang, J. C. Tam, Xiao Sun +10 more
2017Clinical Biochemistry76 citations Open access
Semantic Scholar
Noninvasive prenatal determination of twin zygosity by maternal plasma DNA analysis.
James Z. Z. Qu, Tak Y. Leung, P. Jiang, Gary J. W. Liao +5 more
2013Clinical Chemistry76 citations
Semantic Scholar
DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia.
W. K. Jacky Lam, Wan-Xia Gai, K. Sun, Raymond S. M. Wong +11 more
2017Clinical Chemistry72 citations
Semantic Scholar
Cell-free DNA in maternal plasma and serum: A comparison of quantity, quality and tissue origin using genomic and epigenomic approaches.
F. Wong, K. Sun, P. Jiang, Y. Cheng +4 more
2016Clinical Biochemistry72 citations
Semantic Scholar
Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma
S. C. Yu, P. Jiang, K. Choy, K. Chan +7 more
2013PLoS ONE72 citations Open access
Semantic Scholar
Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases
W. K. Jacky Lam, P. Jiang, K. A. Allen Chan, Wen-Lei Peng +12 more
2019Nature Communications68 citations Open access
Semantic Scholar
Liver- and Colon-Specific DNA Methylation Markers in Plasma for Investigation of Colorectal Cancers with or without Liver Metastases.
Wan-Xia Gai, Lu Ji, W. K. Jacky Lam, K. Sun +12 more
2018Clinical Chemistry68 citations
Semantic Scholar
Leveraging FPGAs for Accelerating Short Read Alignment
James Arram, Thomas Kaplan, W. Luk, P. Jiang
2017IEEE/ACM Transactions on Computational Biology & Bioinformatics68 citations
Semantic Scholar
Single-molecule Sequencing Enables Long Cell-free DNA Detection and Direct Methylation Analysis for Cancer Patients.
L. Y. Lois Choy, Wen-Lei Peng, P. Jiang, Suk H. Cheng +11 more
2022Clinical Chemistry66 citations Open access
Semantic Scholar
Noninvasive Detection of Bladder Cancer by Shallow-Depth Genome-Wide Bisulfite Sequencing of Urinary Cell-Free DNA for Methylation and Copy Number Profiling.
Timothy H. T. Cheng, P. Jiang, J. Y. Teoh, Macy M. S. Heung +9 more
2019Clinical Chemistry66 citations
Semantic Scholar
Bioinformatics Approaches for Fetal DNA Fraction Estimation in Noninvasive Prenatal Testing
X. Peng, P. Jiang
2017International Journal of Molecular Sciences66 citations Open access
Semantic Scholar
Comparison of Single Molecule, Real-Time Sequencing and Nanopore Sequencing for Analysis of the Size, End-Motif, and Tissue-of-Origin of Long Cell-Free DNA in Plasma.
S. C. Yu, Jiaen Deng, Rong Qiao, Suk H. Cheng +11 more
2022Clinical Chemistry61 citations Open access
Semantic Scholar
Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction
R. W. Chan, Lee Serpas, Meng Ni, Stefano Volpi +21 more
2020American Journal of Human Genetics58 citations Open access
Semantic Scholar
Methy-Pipe: An Integrated Bioinformatics Pipeline for Whole Genome Bisulfite Sequencing Data Analysis
P. Jiang, K. Sun, Fiona M. F. Lun, Andy M. Guo +5 more
2014PLoS ONE56 citations Open access
Semantic Scholar
Noninvasive detection of F8 int22h-related inversions and sequence variants in maternal plasma of hemophilia carriers.
I. Hudecova, P. Jiang, J. Davies, Y. M. Dennis Lo +2 more
2017Blood54 citations Open access
Semantic Scholar
Noninvasive prenatal testing by nanopore sequencing of maternal plasma DNA: feasibility assessment.
Suk H. Cheng, P. Jiang, K. Sun, Y. Cheng +4 more
2015Clinical Chemistry49 citations Open access
Semantic Scholar
Hardware Acceleration of Genetic Sequence Alignment
James Arram, Kuen-Hung Tsoi, W. Luk, P. Jiang
2013International Workshop on Applied Reconfigurable Computing45 citations Open access
Semantic Scholar
Characteristics of Fetal Extrachromosomal Circular DNA in Maternal Plasma: Methylation Status and Clearance.
S. Sin, Lu Ji, Jiaen Deng, P. Jiang +7 more
2021Clinical Chemistry42 citations Open access
Semantic Scholar

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