A. Mercer

Most-cited papers

Chimeric TALE recombinases with programmable DNA sequence specificity
A. Mercer, T. Gaj, Roberta P. Fuller, C. Barbas
2012Nucleic Acids Research130 citations Open access
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Directed evolution of the TALE N-terminal domain for recognition of all 5′ bases
B. M. Lamb, A. Mercer, C. Barbas
2013Nucleic Acids Research128 citations Open access
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Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.
J. Meier, A. Mercer, Heriberto Rivera, M. Burkart
2006Journal of the American Chemical Society113 citations
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The ubiquitous carrier protein--a window to metabolite biosynthesis.
A. Mercer, M. Burkart
2007Natural product reports (Print)112 citations
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In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues.
K. Clarke, A. Mercer, J. L. La Clair, M. Burkart
2005Journal of the American Chemical Society89 citations
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Structure-guided reprogramming of serine recombinase DNA sequence specificity
T. Gaj, A. Mercer, C. Gersbach, R. Gordley +1 more
2010Proceedings of the National Academy of Sciences of the United States of America69 citations Open access
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A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells
T. Gaj, A. Mercer, S. Sirk, Heather L. Smith +1 more
2013Nucleic Acids Research61 citations Open access
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Regulation of Endogenous Human Gene Expression by Ligand-Inducible TALE Transcription Factors
A. Mercer, T. Gaj, S. Sirk, B. M. Lamb +1 more
2013ACS Synthetic Biology59 citations Open access
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Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase
C. Gersbach, T. Gaj, R. Gordley, A. Mercer +1 more
2011Nucleic Acids Research59 citations Open access
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Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies
Saravanan Rajan, Michael R. Kierny, A. Mercer, Jin-Cheng Wu +5 more
2018Communications Biology41 citations Open access
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Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors
Bradley S Hollidge, Hayley B. Carroll, R. Qian, Madison L. Fuller +6 more
2022Frontiers in Neurology36 citations Open access
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Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes.
J. Meier, A. Mercer, M. Burkart
2008Journal of the American Chemical Society29 citations
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Enhancing the Specificity of Recombinase-Mediated Genome Engineering through Dimer Interface Redesign
T. Gaj, S. Sirk, R. Tingle, A. Mercer +2 more
2014Journal of the American Chemical Society28 citations Open access
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Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants
S. Sirk, T. Gaj, A. Jonsson, A. Mercer +1 more
2014Nucleic Acids Research25 citations Open access
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Antibiotic Evaluation and In Vivo Analysis of Alkynyl Coenzyme A Antimetabolites in Escherichia Coli
A. Mercer, J. Meier, G. Hur, Andrew R. Smith +1 more
2008Bioorganic & Medicinal Chemistry Letters23 citations Open access
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In Vivo Modification of Native Carrier Protein Domains
A. Mercer, Jordan L. Meier, J. Torpey, M. Burkart
2009ChemBioChem21 citations Open access
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Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells
Yusuf B. Johari, A. Mercer, Ye Liu, Adam J. Brown +1 more
2021Biotechnology and Bioengineering18 citations Open access
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Structure of the AAVhu.37 capsid by cryoelectron microscopy.
J. Kaelber, S. Yost, Keith A Webber, E. Firlar +3 more
2020Acta Crystallographica Section F Structural Biology Communications13 citations Open access
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Fluorescent Multiplex Analysis of Carrier Protein Post‐Translational Modification
A. Mercer, J. L. La Clair, M. Burkart
2005ChemBioChem11 citations
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Editorial: Viral vector-based gene therapy in neurological disease: The future is now
Jared B. Smith, L. Cancedda, S. Jóźwiak, A. Mercer
2023Frontiers in Neurology3 citations Open access
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Chemical expansion of cofactor activity
A. Mercer, M. Burkart
2006Nature Chemical Biology3 citations
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The ubiquitous carrier proteina window to metabolite biosynthesis
A. Mercer, M. Burkart
20072 citations
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Adeno-associated virus strain AAVhu.37 capsid icosahedral structure
Jason T. Kaelber, S. Yost, Emre Firlar, A. Mercer
20190 citations
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Co-opting CoA biosynthesis for the in vivo modification of carrier proteins
A. Mercer
20080 citations
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Enzyme-assisted antibiotic engineering--the Wright way.
A. Mercer, M. Burkart
2005Chemistry and Biology0 citations Open access
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