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M. Gorrell · SciRah

Researcher profile · Semantic Scholar

M. Gorrell

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M. Gorrell — researcher profile on SciRah

h-index: 49
Works: 185
Citations: 7,930

Most-cited papers

Diabetes and nonalcoholic Fatty liver disease: a pathogenic duo.
K. H. Williams, N. Shackel, M. Gorrell, S. Mclennan +1 more
2013Endocrine reviews231 citations
Semantic Scholar
Animal and translational models of SARS-CoV-2 infection and COVID-19
M. Johansen, A. Irving, X. Montagutelli, M. Tate +25 more
2020Mucosal Immunology177 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26.
M. Gorrell
2020Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature141 citations
Semantic Scholar
Covid-19 and co-morbidities: a role for Dipeptidyl Peptidase 4 (DPP4) in disease severity?
M. Bassendine, S. Bridge, Geoff McCaughan, M. Gorrell
2020Journal of Diabetes140 citations Open access
Semantic Scholar
Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis.
L. Lo, S. Mclennan, P. Williams, J. Bonner +5 more
2011Journal of Hepatology109 citations
Semantic Scholar
An atypical parvovirus driving chronic tubulointerstitial nephropathy and kidney fibrosis
B. Roediger, Q. Lee, Shweta Tikoo, J. Cobbin +26 more
2018Cell102 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial.
M. Gorrell
2019Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature89 citations
Semantic Scholar
Advances in Understanding the Expression and Function of Dipeptidyl Peptidase 8 and 9
H. Zhang, Yi-Qian Chen, F. M. Keane, M. Gorrell
2013Molecular Cancer Research81 citations Open access
Semantic Scholar
Fibroblast activation protein in liver fibrosis.
Angelina J. Lay, H. Zhang, G. Mccaughan, M. Gorrell
2019Frontiers in Bioscience71 citations
Semantic Scholar
Incretin‐based therapies – review of the physiology, pharmacology and emerging clinical experience
Jennifer H. Martin, C. Deacon, M. Gorrell, J. Prins
2011Internal medicine journal (Print)70 citations
Semantic Scholar
Soluble CD26 / Dipeptidyl Peptidase IV Enhances Human Lymphocyte Proliferation In Vitro Independent of Dipeptidyl Peptidase Enzyme Activity and Adenosine Deaminase Binding
Dmitrieva K. Yu, L. Slaitini, V. Gysbers, A. G. M. Riekhoff +6 more
2011Scandinavian Journal of Immunology61 citations
Semantic Scholar
A Novel Role of Dipeptidyl Peptidase 9 in Epidermal Growth Factor Signaling
Tsun-Wen Yao, Woo‐Shin Kim, D. Yu, G. Sharbeen +4 more
2011Molecular Cancer Research60 citations Open access
Semantic Scholar
Identification of novel dipeptidyl peptidase 9 substrates by two‐dimensional differential in‐gel electrophoresis
H. Zhang, Sadiqa Maqsudi, A. Rainczuk, Nadine Duffield +6 more
2015The FEBS Journal59 citations
Semantic Scholar
Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics*
H. Zhang, Elizabeth J. Hamson, M. Koczorowska, S. Tholen +12 more
2018Molecular & Cellular Proteomics56 citations Open access
Semantic Scholar
Circulating dipeptidyl peptidase‐4 activity correlates with measures of hepatocyte apoptosis and fibrosis in non‐alcoholic fatty liver disease in type 2 diabetes mellitus and obesity: A dual cohort cross‐sectional study
K. H. Williams, Ana Júlia Vieira De Ribeiro, E. Prakoso, A. Veillard +11 more
2015Journal of Diabetes56 citations Open access
Semantic Scholar
Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives
Gayan S. Jayawickrama, A. Nematollahi, Guanchen Sun, M. Gorrell +1 more
2017Scientific Reports55 citations Open access
Semantic Scholar
Targeted Inactivation of Dipeptidyl Peptidase 9 Enzymatic Activity Causes Mouse Neonate Lethality
Margaret G. Gall, Yi-Qian Chen, Ana Julia Vieira de Ribeiro, H. Zhang +4 more
2013PLoS ONE54 citations Open access
Semantic Scholar
Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growth.
J. Manos, Jonathan W. Arthur, B. Rose, S. Bell +7 more
2009FEMS Microbiology Letters49 citations
Semantic Scholar
Deletion of fibroblast activation protein provides atheroprotection.
S. Stein, Julien Weber, Stefanie Nusser-Stein, J. Pahla +12 more
2020Cardiovascular Research42 citations Open access
Semantic Scholar
The pro‐fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride‐induced experimental liver injury
X. M. Wang, Lauren E. Holz, S. Chowdhury, Shaun-Paul Cordoba +12 more
2017Immunology and Cell Biology42 citations
Semantic Scholar
Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.
S. Chowdhury, Yi-Qian Chen, Tsun-Wen Yao, Katerina Ajami +7 more
2013World Journal of Gastroenterology41 citations Open access
Semantic Scholar
Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin.
H. Zhang, Yi-Qian Chen, C. Wadham, G. Mccaughan +2 more
2015Biochimica et Biophysica Acta39 citations Open access
Semantic Scholar
DPP4 Inhibitor Sitagliptin Enhances Lymphocyte Recruitment and Prolongs Survival in a Syngeneic Ovarian Cancer Mouse Model
Amy Wilson, Laura R. Moffitt, K. Wilson, M. Bilandzic +5 more
2021Cancers37 citations Open access
Semantic Scholar
Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma.
Pok-Fai Wong, Margaret G. Gall, W. Bachovchin, G. Mccaughan +2 more
2016Peptides37 citations
Semantic Scholar
Kynurenine Aminotransferases and the Prospects of Inhibitors for the Treatment of Schizophrenia.
Gayan S. Jayawickrama, R. Sadig, Guanchen Sun, A. Nematollahi +4 more
2015Current Medicinal Chemistry37 citations
Semantic Scholar
Lower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity.
K. H. Williams, A. J. Viera de Ribeiro, E. Prakoso, A. Veillard +12 more
2015Diabetes Research and Clinical Practice36 citations
Semantic Scholar
DPP9 deficiency: an Inflammasomopathy which can be rescued by lowering NLRP1/IL-1 signaling
C. Harapas, K. Robinson, Kenneth Lay, J. Wong +25 more
2022Science immunology35 citations Open access
Semantic Scholar
Animal models for hepatocellular carcinoma.
H. Zhang, James M Henderson, M. Gorrell
2019Biochimica et Biophysica Acta - Molecular Basis of Disease35 citations Open access
Semantic Scholar
Multiple liver insults synergize to accelerate experimental hepatocellular carcinoma
James M Henderson, N. Polak, Jin-Biao Chen, B. Roediger +5 more
2018Scientific Reports33 citations Open access
Semantic Scholar
Discoidin domain receptor 1: isoform expression and potential functions in cirrhotic human liver.
Sunmi Song, N. Shackel, X. M. Wang, Katerina Ajami +2 more
2011American Journal of Pathology31 citations Open access
Semantic Scholar
A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2
Cecy Xi, Arianna Di Fazio, N. Nadvi, Karishma Patel +14 more
2020Molecules30 citations Open access
Semantic Scholar
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
Xin Tracy Liu, Yu Huang, Da Liu, Y. Jiang +21 more
2024Journal of Translational Medicine27 citations Open access
Semantic Scholar
Differential chemokine receptor expression and usage by pre‐cDC1 and pre‐cDC2
Stuart J Cook, Q. Lee, Alex C H Wong, B. Spann +6 more
2018Immunology and Cell Biology27 citations
Semantic Scholar
Dipeptidyl Peptidase Inhibition Enhances CD8 T Cell Recruitment and Activates Intrahepatic Inflammasome in a Murine Model of Hepatocellular Carcinoma
James M Henderson, M. Xiang, Jiali Carrie Huang, S. Wetzel +9 more
2021Cancers26 citations Open access
Semantic Scholar
Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein
Xin Tracy Liu, L. Chung, Da Liu, Jin-Biao Chen +14 more
2022Oncogenesis25 citations Open access
Semantic Scholar
Circulating Fibroblast Activation Protein and Dipeptidyl Peptidase 4 in Rheumatoid Arthritis and Systemic Sclerosis
P. Sinnathurai, W. Lau, Ana Julia Vieira de Ribeiro, W. Bachovchin +5 more
2016International Journal of Rheumatic Diseases25 citations Open access
Semantic Scholar
Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease
S. Uitte de Willige, F. M. Keane, D. Bowen, J. Malfliet +6 more
2017PLoS ONE23 citations Open access
Semantic Scholar
Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes.
Yi-Qian Chen, Margaret G. Gall, H. Zhang, F. M. Keane +3 more
2016Experimental Cell Research22 citations
Semantic Scholar
Differential Effects of ‘Vaping’ on Lipid and Glucose Profiles and Liver Metabolic Markers in Obese Versus Non-obese Mice
Hui Chen, Gerard E Li, Y. Chan, H. Zhang +4 more
2021Frontiers in Physiology21 citations Open access
Semantic Scholar
Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells
Laura R. Moffitt, M. Bilandzic, Amy Wilson, Yi-Qian Chen +4 more
2020International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches
Claire Wilson, H. Zhang, M. Gorrell, C. Abbott
2016Biological chemistry21 citations
Semantic Scholar
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
Oguz Bolgi, M. Silva-García, B. Ross, Esther Pilla +14 more
2022EMBO Reports20 citations Open access
Semantic Scholar
DPP9: Comprehensive In Silico Analyses of Loss of Function Gene Variants and Associated Gene Expression Signatures in Human Hepatocellular Carcinoma
Jiali Carrie Huang, A. Al Emran, J. Endaya, G. Mccaughan +2 more
2021Cancers20 citations Open access
Semantic Scholar
DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues.
E. Harstad, J. Rosenblum, M. Gorrell, William E. Achanzar +9 more
2013Regulatory Peptides20 citations
Semantic Scholar
High resolution crystal structures of human kynurenine aminotransferase‐I bound to PLP cofactor, and in complex with aminooxyacetate
N. Nadvi, N. Salam, Joo-Ung Park, Fady N. Akladios +4 more
2017Protein Science17 citations Open access
Semantic Scholar
Non-Invasive Fluorescent Monitoring of Ovarian Cancer in an Immunocompetent Mouse Model
Amy Wilson, K. Wilson, M. Bilandzic, Laura R. Moffitt +6 more
2018Cancers16 citations Open access
Semantic Scholar
Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I.
Fady N. Akladios, N. Nadvi, Joo-Ung Park, J. Hanrahan +3 more
2012Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Long Term Ex-Situ Normothermic Machine Perfusion Allows Regeneration of Human Livers with Severe Bile Duct Injury.
M. Ly, Ngee-Soon Lau, Claude Dennis, Jinbiao Chen +11 more
2024American Journal of Transplantation15 citations Open access
Semantic Scholar
Circulating Dipeptidyl Peptidase Activity Is a Potential Biomarker for Inflammatory Bowel Disease
S. Jaenisch, C. Abbott, M. Gorrell, P. Bampton +2 more
2022Clinical and Translational Gastroenterology15 citations Open access
Semantic Scholar
Hepatocellular carcinoma: Mouse models and the potential roles of proteases.
James M Henderson, H. Zhang, N. Polak, M. Gorrell
2017Cancer Letters15 citations
Semantic Scholar

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