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A. Lehmann · SciRah

Researcher profile · Semantic Scholar

A. Lehmann

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A. Lehmann — researcher profile on SciRah

h-index: 22
Works: 42
Citations: 2,013

Most-cited papers

PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (her2) therapy in primary HER2-overexpressing breast cancer.
S. Loibl, G. von Minckwitz, A. Schneeweiss, S. Paepke +21 more
2014Journal of Clinical Oncology252 citations Open access
Semantic Scholar
Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer - overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression
B. Müller, Lisa Jana, A. Kasajima, A. Lehmann +6 more
2013BMC Cancer245 citations Open access
Semantic Scholar
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma
P. Bischoff, A. Trinks, B. Obermayer, J. P. Pett +16 more
2020bioRxiv223 citations Open access
Semantic Scholar
A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance
M. Dietel, K. Jöhrens, M. Laffert, M. Hummel +11 more
2015Cancer Gene Therapy133 citations Open access
Semantic Scholar
KRAS genotyping of paraffin-embedded colorectal cancer tissue in routine diagnostics: comparison of methods and impact of histology.
W. Weichert, C. Schewe, A. Lehmann, C. Sers +8 more
2010Journal of Molecular Diagnostics101 citations Open access
Semantic Scholar
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo
A. Lehmann, C. Denkert, J. Budczies, A. Buckendahl +8 more
2009BMC Cancer96 citations Open access
Semantic Scholar
Contribution of human papilloma virus to the incidence of squamous cell carcinoma of the head and neck in a European population with high smoking prevalence.
I. Tinhofer, K. Jöhrens, U. Keilholz, A. Kaufmann +19 more
2015European Journal of Cancer87 citations
Semantic Scholar
DNA methylation-based classification of sinonasal tumors
Philipp Jurmeister, S. Gloss, Renée Roller, M. Leitheiser +62 more
2022Nature Communications82 citations Open access
Semantic Scholar
The EndoPredict Gene-Expression Assay in Clinical Practice - Performance and Impact on Clinical Decisions
B. Müller, E. Keil, A. Lehmann, K. Winzer +15 more
2013PLoS ONE78 citations Open access
Semantic Scholar
Comparison of targeted next-generation sequencing and Sanger sequencing for the detection of PIK3CA mutations in breast cancer
R. Arsenic, D. Treue, A. Lehmann, M. Hummel +3 more
2015BMC Clinical Pathology75 citations Open access
Semantic Scholar
Predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance
Manfred Dietel, K. Jöhrens, M. Laffert, M. Hummel +8 more
2013Cancer Gene Therapy74 citations Open access
Semantic Scholar
Analysis of PIK3CA Mutations in Breast Cancer Subtypes
R. Arsenic, A. Lehmann, J. Budczies, Ines Koch +6 more
2014Applied immunohistochemistry & molecular morphology (Print)58 citations
Semantic Scholar
Testing NTRK testing: Wet‐lab and in silico comparison of RNA‐based targeted sequencing assays
N. Pfarr, M. Kirchner, U. Lehmann, J. Leichsenring +22 more
2020Genes, Chromosomes and Cancer54 citations
Semantic Scholar
Phenotypic and genotypic characterization of carcinomas of the papilla of Vater has prognostic and putative therapeutic implications.
I. Kohler, D. Jacob, J. Budzies, A. Lehmann +4 more
2011American Journal of Clinical Pathology51 citations Open access
Semantic Scholar
KRAS Mutations in Codon 12 or 13 Are Associated With Worse Prognosis in Pancreatic Ductal Adenocarcinoma
B. Sinn, J. Striefler, Marc Rudl, A. Lehmann +11 more
2014Pancreas44 citations
Semantic Scholar
Machine learning models predict the primary sites of head and neck squamous cell carcinoma metastases based on DNA methylation
M. Leitheiser, D. Capper, P. Seegerer, A. Lehmann +5 more
2021Journal of Pathology37 citations Open access
Semantic Scholar
Human papilloma virus status of penile squamous cell carcinoma is associated with differences in tumour-infiltrating T lymphocytes
P. Lohneis, Ş. Boral, A. Kaufmann, A. Lehmann +4 more
2015Virchows Archiv36 citations
Semantic Scholar
Multicenter Evaluation of a Novel Automated Rapid Detection System of BRAF Status in Formalin-Fixed, Paraffin-Embedded Tissues.
A. Schiefer, Laura Parlow, L. Gabler, I. Mesteri +13 more
2016Journal of Molecular Diagnostics35 citations Open access
Semantic Scholar
Validation and comparison of two NGS assays for the detection of EGFR T790M resistance mutation in liquid biopsies of NSCLC patients
C. Vollbrecht, A. Lehmann, D. Lenze, M. Hummel
2018OncoTarget34 citations Open access
Semantic Scholar
EGFR T790M mutation testing of non-small cell lung cancer tissue and blood samples artificially spiked with circulating cell-free tumor DNA: results of a round robin trial
J. Fassunke, M. Ihle, D. Lenze, A. Lehmann +16 more
2017Virchows Archiv32 citations
Semantic Scholar
NTRK testing: First results of the QuiP‐EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA‐based NGS assays
M. Kirchner, J. Glade, U. Lehmann, S. Merkelbach-Bruse +20 more
2020Genes, Chromosomes and Cancer28 citations Open access
Semantic Scholar
RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance
C. Vollbrecht, D. Lenze, M. Hummel, A. Lehmann +7 more
2018BMC Cancer26 citations Open access
Semantic Scholar
Clinical Impact of Rare and Compound Mutations of Epidermal Growth Factor Receptor in Patients With Non-Small-Cell Lung Cancer.
Juliane Martin, A. Lehmann, F. Klauschen, M. Hummel +10 more
2019Clinical Lung Cancer20 citations
Semantic Scholar
B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased
J. Ihlow, E. Michaelis, Selina Greuel, V. Heynol +11 more
2021International Journal of Infectious Diseases18 citations Open access
Semantic Scholar
The Prognostic Significance of p16 and its Role as a Surrogate Marker for Human Papilloma Virus in Oral Squamous Cell Carcinoma: An Analysis of 281 Cases
Christian Doll, C. Steffen, B. Beck-Broichsitter, Maximilian Richter +9 more
2022Anticancer Research17 citations
Semantic Scholar
Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer - overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression
B. Müller, Lisa Jana, A. Kasajima, A. Lehmann +6 more
2013BMC Cancer16 citations Open access
Semantic Scholar
Abstract S4-06: PIK3CA mutation predicts resistance to anti-HER2/chemotherapy in primary HER2-positive/hormone-receptor-positive breast cancer – Prospective analysis of 737 participants of the GeparSixto and GeparQuinto studies
S. Loibl, C. Denkert, A. Schneeweiss, S. Paepke +19 more
201315 citations
Semantic Scholar
Intratumoral morphological heterogeneity can be an indicator of genetic heterogeneity in colorectal cancer.
Julia C. Büttner, K. Jöhrens, F. Klauschen, M. Hummel +3 more
2018Experimental and molecular pathology (Print)12 citations
Semantic Scholar
Proficiency testing of PIK3CA mutations in HR+/HER2-breast cancer on liquid biopsy and tissue
C. Vollbrecht, Inga Hoffmann, A. Lehmann, S. Merkelbach-Bruse +15 more
2022Virchows Archiv10 citations Open access
Semantic Scholar
A fast, cost‐efficient and sensitive approach for KRAS mutation detection using multiplexed primer extension with IP/RP‐HPLC separation
S. Tierling, C. Sers, A. Lehmann, J. Walter
2012International Journal of Cancer8 citations Open access
Semantic Scholar
Applicability of a System for Fully Automated Nucleic Acid Extraction From Formalin-fixed Paraffin-embedded Sections for Routine KRAS Mutation Testing
A. Lehmann, C. Schewe, G. Hennig, C. Denkert +3 more
2012Diagnostic molecular pathology (Print)6 citations Open access
Semantic Scholar
COVID-19: B-Cell Depletion and Sepsis Related Changes in Bone Marrow and Spleen
J. Ihlow, Ann-Christin von-Bruenneck, E. Michaelis, Selina Greuel +11 more
2020Blood4 citations Open access
Semantic Scholar
Influence of mucinous and necrotic tissue in colorectal cancer samples on KRAS mutation analysis.
Julia C. Büttner, A. Lehmann, F. Klauschen, M. Hummel +3 more
2017Pathology, Research and Practice4 citations
Semantic Scholar
Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies
K. Kleo, V. Jovanović, Alexander Arndold, A. Lehmann +6 more
2022Journal of Cancer Research and Clinical Oncology3 citations Open access
Semantic Scholar
Comparison of risk assessment in 1652 early ER positive, HER2 negative breast cancer in a real-world data set: classical pathological parameters vs. 12-gene molecular assay (EndoPredict)
P. Jank, J. Lindner, A. Lehmann, B. Pfitzner +5 more
2021Breast Cancer Research and Treatment3 citations Open access
Semantic Scholar
Abstract LB-027: Mutational diversity and therapy response in breast cancer-a sequencing analysis in the neoadjuvant GeparSepto trial
S. Loibl, D. Treue, J. Budczies, K. Weber +20 more
2018Bioinformatics and Systems Biology1 citations
Semantic Scholar
69PA NOVEL MULTIGENE ASSAY IN CLINICAL PRACTICE - PERFORMANCE AND IMPACT ON CLINICAL DECISIONS
B. Sinn, B. Müller, E. Keil, A. Lehmann +5 more
20131 citations Open access
Semantic Scholar
Abstract 4806: Association of changes in 4-aminobutyrate aminotransferase (ABAT) and beta-alanine metabolism with breast cancer and the more aggressive estrogen receptor negative subtype
J. Budczies, A. Lehmann, J. Griffin, M. Orešič +2 more
20121 citations
Semantic Scholar
Tumor mutations predict HER2-targeted therapy resistance in primary HER2-positive breast cancer
M. V. van Mackelenbergh, N. Pfarr, K. Weber, M. Untch +21 more
2026npj Breast Cancer0 citations Open access
Semantic Scholar
Abstract PS4-21: Comparison of risk assessment in primary ER+, HER2- Breast Cancer in a real-world data set: Classical pathological parameters vs. 12-gene molecular assay (EndoPredict)
P. Jank, C. Denkert, J. Lindner, A. Lehmann +5 more
20210 citations
Semantic Scholar
RNA-based analysis of anaplastic lymphoma kinase (ALK) fusions in non-small cell lung cancer (NSCLC) cases showing immunohistochemistry/fluorescence in-situ hybridisation (IHC/FISH) discordance.
Claudia Vollbrecht, D. Lenze, M. Hummel, A. Lehmann +7 more
2018Annals of Oncology0 citations Open access
Semantic Scholar
Abstract 1220:PIK3CAmutations in primary HER2-positive and triple negative breast cancer.
S. Loibl, C. Denkert, S. Loi, F. André +10 more
20130 citations
Semantic Scholar

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