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C. Deivanayagam · SciRah

Researcher profile · Semantic Scholar

C. Deivanayagam

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C. Deivanayagam — researcher profile on SciRah

h-index: 19
Works: 72
Citations: 1,626

Most-cited papers

A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen‐binding MSCRAMM, clumping factor A
C. Deivanayagam, E. Wann, Wei Chen, M. Carson +3 more
2002EMBO Journal192 citations Open access
Semantic Scholar
Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein.
C. Deivanayagam, R. Rich, M. Carson, R. Owens +4 more
2000Structure172 citations Open access
Semantic Scholar
The changing faces of Streptococcus antigen I/II polypeptide family adhesins
L. Brady, S. Maddocks, M. Larson, N. Forsgren +3 more
2010Molecular Microbiology166 citations Open access
Semantic Scholar
Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of α- and PPII-helices
M. Larson, K. Rajashankar, M. Patel, R. Robinette +4 more
2010Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
B. Todd, D. Moore, C. Deivanayagam, G. Lin +4 more
2003Journal of Molecular Biology105 citations
Semantic Scholar
Trench-shaped Binding Sites Promote Multiple Classes of Interactions between Collagen and the Adherence Receptors, α1β1 Integrin and Staphylococcus aureus Cna MSCRAMM*
R. Rich, C. Deivanayagam, R. Owens, M. Carson +5 more
1999Journal of Biological Chemistry93 citations Open access
Semantic Scholar
Structural and Biochemical Characterization of Staphylococcus aureus Clumping Factor B/Ligand Interactions*
V. Ganesh, E. Barbu, C. Deivanayagam, Binh Le +6 more
2011Journal of Biological Chemistry85 citations Open access
Semantic Scholar
Crystal Structure of the C-terminal Region of Streptococcus mutans Antigen I/II and Characterization of Salivary Agglutinin Adherence Domains*♦
M. Larson, K. Rajashankar, P. Crowley, C. Kelly +3 more
2011Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Structural Organization of the Fibrinogen-binding Region of the Clumping Factor B MSCRAMM of Staphylococcus aureus *
S. Perkins, E. Walsh, C. Deivanayagam, S. Narayana +2 more
2001Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Antigen I/II mediates interactions between Streptococcus mutans and Candida albicans
Changyi Yang, J. Scoffield, R. Wu, C. Deivanayagam +2 more
2018Molecular Oral Microbiology60 citations Open access
Semantic Scholar
Domain structure of the Staphylococcus aureus collagen adhesin.
R. Rich, B. Demeler, K. Ashby, C. Deivanayagam +4 more
1998Biochemistry58 citations
Semantic Scholar
TLR4‐mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis
Amit R. Ashtekar, Ping Zhang, J. Katz, C. Deivanayagam +3 more
2008Journal of Leukocyte Biology57 citations Open access
Semantic Scholar
Structural and Functional Characterization of the Mumps Virus Phosphoprotein
R. Cox, T. Green, S. Purushotham, C. Deivanayagam +3 more
2013Journal of Virology56 citations Open access
Semantic Scholar
Glucan Binding Protein C of Streptococcus mutans Mediates both Sucrose-Independent and Sucrose-Dependent Adherence
Joshua L. Mieher, M. Larson, N. Schormann, S. Purushotham +4 more
2018Infection and Immunity43 citations Open access
Semantic Scholar
Structure of FKBP12.6 in complex with rapamycin.
C. Deivanayagam, M. Carson, Aruna Thotakura, S. Narayana +1 more
2000Acta Crystallographica Section D: Biological Crystallography40 citations
Semantic Scholar
The Calcium-induced Conformation and Glycosylation of Scavenger-rich Cysteine Repeat (SRCR) Domains of Glycoprotein 340 Influence the High Affinity Interaction with Antigen I/II Homologs*
S. Purushotham, C. Deivanayagam
2014Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM.
R. Rich, C. Deivanayagam, R. Owens, M. Carson +6 more
1999Journal of Biological Chemistry24 citations
Semantic Scholar
Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.
H. M. McDonald, Pamela S. Pruett, C. Deivanayagam, Irina I. Protasevich +4 more
2007Acta Crystallographica Section D: Biological Crystallography21 citations
Semantic Scholar
Characterization of the pgf operon involved in the posttranslational modification of Streptococcus mutans surface proteins
Alejandro Avilés-Reyes, I. A. Freires, R. Besingi, S. Purushotham +4 more
2018Scientific Reports20 citations Open access
Semantic Scholar
Crystallization of ClfA and ClfB fragments: the fibrinogen-binding surface proteins of Staphylococcus aureus.
C. Deivanayagam, S. Perkins, Sita Danthuluri, R. Owens +5 more
1999Acta Crystallographica Section D: Biological Crystallography18 citations
Semantic Scholar
The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis
N. Schormann, M. Patel, Luke Thannickal, S. Purushotham +4 more
2023Acta Crystallographica Section F Structural Biology Communications16 citations Open access
Semantic Scholar
Erratum: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM (Journal of Biological Chemistry (1999) 274 (24906-24913))
R. Rich, C. Deivanayagam, R. Owens, M. Carson +6 more
199914 citations
Semantic Scholar
ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4
R. Hammond, N. Schormann, R. McPherson, A. Leung +2 more
2021Proceedings of the National Academy of Sciences of the United States of America12 citations Open access
Semantic Scholar
Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides
Gaurav Nayyar, V. Mishra, Shaila P. Handattu, M. Palgunachari +6 more
2012Journal of Lipid Research12 citations Open access
Semantic Scholar
Crystallization and preliminary X-ray crystallographic analysis of Ace: a collagen-binding MSCRAMM from Enterococcus faecalis.
K. Ponnuraj, Yi Xu, D. Moore, C. Deivanayagam +3 more
2002Biochimica et Biophysica Acta11 citations
Semantic Scholar
Hydrogel encapsulated biofilm inhibitors abrogate the cariogenic activity of Streptococcus mutans
Parmanand Ahirwar, V. Kozlovskaya, Bhavitavya Nijampatnam, Edwin M Rojas +11 more
2023Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
The Oxidative Stress-Induced Hypothetical Protein PG_0686 in Porphyromonas gingivalis W83 Is a Novel Diguanylate Cyclase
Alexia Ximinies, Y. Dou, A. Mishra, Kang-Ling Zhang +3 more
2023Microbiology spectrum7 citations Open access
Semantic Scholar
Streptococcus mutans Collagen‐Binding Protein Cnm Is a Multifunctional Adhesin: A Structural Investigation
Joshua L. Mieher, Norbert Schormann, R. Wu, M. Patel +5 more
2025Molecular Oral Microbiology6 citations Open access
Semantic Scholar
The Glycoprotein 340’s Scavenger Receptor Cysteine-Rich Domain Promotes Adhesion of Staphylococcus aureus and Pseudomonas aeruginosa to Contact Lens Polymers
K. Osei, Joshua L. Mieher, M. Patel, J. Nichols +1 more
2021Infection and Immunity6 citations Open access
Semantic Scholar
Cloning, Expression and Purification of the SRCR domains of glycoprotein 340
S. Purushotham, C. Deivanayagam
2013Protein Expression and Purification6 citations Open access
Semantic Scholar
PMS2 variant results in loss of ATPase activity without compromising mismatch repair
B. D’Arcy, Jennifer M. Arrington, Justin Weisman, S. B. McClellan +5 more
2022Molecular Genetics & Genomic Medicine5 citations Open access
Semantic Scholar
Interaction of βA3-Crystallin with Deamidated Mutants of αA- and αB-Crystallins
E. Tiwary, Shylaja Hegde, S. Purushotham, C. Deivanayagam +1 more
2015PLoS ONE4 citations Open access
Semantic Scholar
Systemic checkpoint blockade by PD-L1 single-chain antibody confers potent anti-tumor immunity and long-term survival
Hong Wang, Vinayak Khattar, J. Hensel, Reading Ashton +7 more
2022Molecular Cancer Therapeutics3 citations Open access
Semantic Scholar
Characterization of FA1654: a putative DPS protein in Filifactor alocis
Malissa Mangar, A. Mishra, Zheng-Rong Yang, C. Deivanayagam +1 more
2022Molecular Oral Microbiology3 citations Open access
Semantic Scholar
Structural and functional analysis of the C-terminal region of Streptococcus gordonii SspB.
N. Schormann, S. Purushotham, Joshua L. Mieher, M. Patel +2 more
2021Acta Crystallographica Section D: Structural Biology3 citations Open access
Semantic Scholar
Structure-Function Characterization of Streptococcus intermedius Surface Antigen Pas
Joshua L. Mieher, N. Schormann, R. Wu, M. Patel +4 more
2021Journal of Bacteriology3 citations Open access
Semantic Scholar
PG1659 functions as anti-sigma factor to extracytoplasmic function sigma factor RpoE in Porphyromonas gingivalis W83
Y. Dou, Hiel Rutanhira, N. Schormann, C. Deivanayagam +1 more
2020Molecular Oral Microbiology3 citations Open access
Semantic Scholar
Crystallization and preliminary X-ray analysis of B-domain fragments of a Staphylococcus aureus collagen-binding protein.
C. Deivanayagam, R. Rich, Sita Danthuluri, R. Owens +4 more
1999Acta Crystallographica Section D: Biological Crystallography2 citations
Semantic Scholar
The structure of Streptococcus gordonii surface protein SspB in complex with TEV peptide provides clues to oral streptococcal adherence to salivary agglutinin
Joshua L. Mieher, Norbert Schormann, S. Purushotham, Veena B. Krishnan +4 more
2026Infection and Immunity1 citations Open access
Semantic Scholar
Crystal structure of truncated Streptococcal bacteriophage hyaluronidase complexed with unsaturated hyaluronan hexa-saccharides
C. Deivanayagam, N. Schormann
20211 citations
Semantic Scholar
Crystal structure of full-length Streptococcal bacteriophage hyaluronidase in complex with unsaturated hyaluronan octa-saccharides
C. Deivanayagam, N. Schormann
20211 citations
Semantic Scholar
Crystal structure of truncated bacteriophage hyaluronan lyase HylP in complex with unsaturated hyaluronan tetra-saccharides
C. Deivanayagam, N. Schormann
20211 citations
Semantic Scholar
CRYSTAL STRUCTURE OF THE C-TERMINUS OF STREPTOCOCCUS MUTANS ANTIGEN I/II AND CHARACTERIZATION OF SALIVARY AGGLUTININ ADHERENCE DOMAINS
M. Larson, K. Rajashankar, P. Crowley, C. Kelly +4 more
20111 citations
Semantic Scholar
CRYSTAL STRUCTURE OF FKBP12.6 IN COMPLEX WITH RAPAMYCIN
C. Deivanayagam, M. Carson, A. Thotakura, S. Narayana +1 more
20001 citations
Semantic Scholar
Targeting Streptococcus mutans Antigen I/II To Inhibit Dual-Species Biofilms with Candida albicans
B. O. Garrett, Parvathy Babu, Bhavitavya Nijampatnam, Abhishek Govindan +7 more
2026ACS Medicinal Chemistry Letters0 citations Open access
Semantic Scholar
CSIG-21. LINEAGE-SPECIFIC SPLICING OF ANNEXIN A7 MODULATES RECEPTOR TYROSINE KINASE TRAFFICKING THROUGH ISOFORM-SPECIFIC INTERACTIONS IN GLIOBLASTOMA: STRUCTURAL AND THERAPEUTIC INSIGHTS
S. Nair, Aran Merati, R. Rajbhandari, V. Puliyappadamba +3 more
2025Neuro-Oncology0 citations
Semantic Scholar
Structural studies on the glucosyltransferases of Streptococcus mutans
N. Schormann, R. Wu, M. Patel, Hui Wu +1 more
2023Acta Crystallographica Section A: Foundations and Advances0 citations Open access
Semantic Scholar
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells.
K. Osei, C. Deivanayagam, J. Nichols
2023The ocular surface0 citations
Semantic Scholar
Streptococcus gordonii C123 Domain(s)-Structural and Functional Analysis
N. Schormann, C. Deivanayagam
20210 citations
Semantic Scholar
Crystal Structure of Streptococcal Bacteriophage Hyaluronidase: Presence of a Prokaryotic Collagen and Elucidation of Catalytic Mechanism
C. Deivanayagam, N. Schormann
20210 citations
Semantic Scholar

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