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N. Caporarello · SciRah

Researcher profile · Semantic Scholar

N. Caporarello

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N. Caporarello — researcher profile on SciRah

h-index: 15
Works: 46
Citations: 1,047

Most-cited papers

Selective YAP/TAZ Inhibition in Fibroblasts via Dopamine Receptor D1 Agonism Reverses Fibrosis
A. Haak, Enis Kostallari, Delphine Sicard, G. Ligresti +21 more
2019Science Translational Medicine197 citations Open access
Semantic Scholar
COVID-19 Vasculopathy: Mounting Evidence for an Indirect Mechanism of Endothelial Injury
R. Nicosia, G. Ligresti, N. Caporarello, Shreeram Akilesh +1 more
2021American Journal of Pathology95 citations Open access
Semantic Scholar
PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state
N. Caporarello, J. Meridew, Dakota L. Jones, Q. Tan +6 more
2019Thorax86 citations Open access
Semantic Scholar
CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.
G. Ligresti, N. Caporarello, J. Meridew, Dakota L. Jones +9 more
2019JCI Insight84 citations Open access
Semantic Scholar
Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis
N. Caporarello, Jisu Lee, T. Pham, Dakota L. Jones +12 more
2022Nature Communications79 citations Open access
Semantic Scholar
Liver sinusoidal endothelial cell expressed vascular cell adhesion molecule 1 promotes liver fibrosis
Qian-Qian Guo, Kunimaro Furuta, Shahidul Islam, N. Caporarello +5 more
2022Frontiers in Immunology68 citations Open access
Semantic Scholar
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression
Dakota L. Jones, A. Haak, N. Caporarello, K. M. Choi +6 more
2019Journal of Cell Science66 citations Open access
Semantic Scholar
Vascular dysfunction in aged mice contributes to persistent lung fibrosis
N. Caporarello, J. Meridew, Aja Aravamudhan, Dakota L. Jones +10 more
2020Aging Cell63 citations Open access
Semantic Scholar
Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis
A. Raslan, Tho X Pham, Ji-Su Lee, K. Kontodimas +13 more
2024Nature Communications61 citations Open access
Semantic Scholar
Spontaneous Lung Fibrosis Resolution Reveals Novel Anti-Fibrotic Regulators.
Q. Tan, P. Link, J. Meridew, T. Pham +3 more
2021American Journal of Respiratory Cell and Molecular Biology36 citations Open access
Semantic Scholar
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation.
Aja Aravamudhan, A. Haak, K. M. Choi, J. Meridew +5 more
2020American Journal of Physiology - Lung cellular and Molecular Physiology35 citations Open access
Semantic Scholar
Transcriptional analysis of lung fibroblasts identifies PIM1 signaling as a driver of aging-associated persistent fibrosis
T. Pham, Jisu Lee, Jiazhen Guan, N. Caporarello +6 more
2022JCI Insight33 citations Open access
Semantic Scholar
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation
Dakota L. Jones, J. Meridew, P. Link, Merrick T. Ducharme +13 more
2021Journal of Cell Biology31 citations Open access
Semantic Scholar
Mesenchymal Cells in The Lung: Evolving Concepts and Their Role in Fibrosis
G. Ligresti, A. Raslan, Jeongmin Hong, N. Caporarello +2 more
2023Gene28 citations Open access
Semantic Scholar
Vascular Contribution to Lung Repair and Fibrosis.
N. Caporarello, G. Ligresti
2023American Journal of Respiratory Cell and Molecular Biology26 citations Open access
Semantic Scholar
Pim-1 Kinase is a Positive Feedback Regulator of the Senescent Lung Fibroblast Inflammatory Secretome.
A. Gao, A. M. Diaz Espinosa, F. Gianì, T. Pham +7 more
2022American Journal of Physiology - Lung cellular and Molecular Physiology12 citations Open access
Semantic Scholar
Single Cell Transcriptomics of Fibrotic Lungs Unveils Aging-associated Alterations in Endothelial and Epithelial Cell Regeneration
A. Raslan, T. Pham, Jisu Lee, Jeongmin Hong +12 more
2023bioRxiv10 citations Open access
Semantic Scholar
The matricellular protein CCN3 supports lung endothelial homeostasis and function.
K. Betageri, P. Link, A. Haak, G. Ligresti +2 more
2022American Journal of Physiology - Lung cellular and Molecular Physiology10 citations Open access
Semantic Scholar
RUNX1 is a mediator of fibrotic activation and epigenetic memory in lung fibroblasts
R. M. Gilbert, Dakota L. Jones, J. Wellmerling, N. Caporarello +9 more
2026American Journal of Respiratory Cell and Molecular Biology6 citations Open access
Semantic Scholar
CBX 5 / G 9 a / H 3 K 9 me-mediated gene repression is essential to fibroblast activation during lung fibrosis
G. Ligresti, N. Caporarello, J. Meridew, Dakota L. Jones +9 more
20195 citations
Semantic Scholar
Vascular protection by young circulating extracellular vesicles ameliorates aging-related pulmonary fibrosis
F. Gianì, B. Roos, P. Link, Bharath Somasundram +7 more
2025American Journal of Physiology - Cell Physiology4 citations Open access
Semantic Scholar
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation
N. Ring, M. C. Volpe, Tomaž Stepišnik, M. Mamolo +20 more
2021Cell Death and Disease4 citations Open access
Semantic Scholar
Lung-targeted Lipid Nanoparticle Delivery of a Matricellular mRNA Promotes Fibrotic Lung Repair.
K. Betageri, J. Meridew, Brian J. Parrett, R. M. Gilbert +6 more
2025American Journal of Respiratory Cell and Molecular Biology3 citations
Semantic Scholar
Author Correction: Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis
N. Caporarello, Jisu Lee, T. Pham, Dakota L. Jones +12 more
2022Nature Communications3 citations Open access
Semantic Scholar
Endothelial cell interactions with immune cells and fibroblasts in the pulmonary microenvironment: From the developing to the aging lung Sientific Session III ReSPIRE 2025.
N. Caporarello, D. Mehta, Yoshikazu Tsukasaki, A. Sarkar +2 more
2025American Journal of Physiology - Lung cellular and Molecular Physiology2 citations Open access
Semantic Scholar
A redox-shifted fibroblast subpopulation emerges in the fibrotic lung
P. Link, J. Meridew, N. Caporarello, A. Gao +4 more
2023bioRxiv1 citations Open access
Semantic Scholar
Lung injury epigenetically primes mesenchyme for amplified activation upon re-injury
Dakota L. Jones, N. Caporarello, J. Meridew, K. M. Choi +6 more
2022bioRxiv1 citations Open access
Semantic Scholar
ZNF416 is a pivotal transcriptional regulator of fibroblast mechano-activation
Dakota L. Jones, J. Meridew, Merrick T. Ducharme, Katherine L. Lydon +13 more
2020bioRxiv1 citations Open access
Semantic Scholar
Vascular Dysfunction in Aged Mice Contributes to Persistent Lung Fibrosis Through the Impairment of the NO/sGC/cGMP Pathway
N. Caporarello, J. Meridew, Adil J. Haresi, K. M. Choi +8 more
20201 citations Open access
Semantic Scholar
Dysfunctional ERG Signaling Drives Pulmonary Vascular Aging and Progressive Fibrosis
N. Caporarello, T. Pham, J. Lee, J. Guan +7 more
C9. C009 MODULATORS OF LUNG INJURY AND REPAIR1 citations Open access
Semantic Scholar
miRNA expression profiling of lung endothelial cells reveals elevated miR-205-5p in aged mice with persistent lung fibrosis and in IPF-derived endothelial cells
G. Muscato, B. Roos, F. Gianì, P. Link +4 more
2024Mechanisms of lung injury and repair0 citations
Semantic Scholar
Loss of ERG in Capillary Endothelial Cells Is Associated With cGAS-STING Pathway Activation and Aberrant Lung Fibrosis Resolution'
A. Raslan, J. Schmottlach, O. Elbasiony, J. Hong +3 more
2024B98. HEALING LUNGS: NAVIGATING THE PATHWAYS OF LUNG REPAIR0 citations
Semantic Scholar
A Redox-Shifted Fibroblast Subpopulation Emerges in the Fibrotic Lung
P. Link, J. Meridew, N. Caporarello, A. Gao +3 more
2024American Journal of Respiratory Cell and Molecular Biology0 citations Open access
Semantic Scholar
Identification and Characterization of Fibroblast Subpopulations Using Redox in Fibrosis
P. Link, J. Meridew, N. Caporarello, A. Gao +4 more
2023A66. DISSECTING THE MATRIX AND MESENCHYMAL CELLS IN FIBROSIS0 citations
Semantic Scholar
Investigating the Role of YAP/TrkB Signaling in Lung Capillary Endothelial Cell Regeneration and Fibrosis Resolution
A. Raslan, T. Pham, J. Lee, J. Hong +12 more
2023A16. INTERROGATING GENOMIC, TRANSCRIPTIONAL, AND EPIGENETIC MECHANISMS IN LUNG FIBROSIS0 citations
Semantic Scholar
Matricellular Protein CCN3 as a Target to Promote Lung Endothelial Homeostasis and Repair in the Fibrotic Lung
K. R. Betageri, P. Link, A. J. Haak, G. Ligresti +2 more
2023A66. DISSECTING THE MATRIX AND MESENCHYMAL CELLS IN FIBROSIS0 citations
Semantic Scholar
Circulating Extracellular Vesicles Isolated From Young Mice Protect Endothelial Cells and Exert Anti-fibrotic Effects In Vivo and Ex Vivo
F. Gianì, P. Link, N. Javeed, J. Meridew +3 more
2023B65. IMMUNE AND ENDOTHELIAL CELLS HIT BACK AT LUNG REPAIR0 citations
Semantic Scholar
Characterization of Lung Endothelial Cell Heterogeneity in Idiopathic Pulmonary Fibrosis (IPF)
J. Lee, T. Pham, N. Caporarello, S. Huang +1 more
2022A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY0 citations
Semantic Scholar
Dopamine Synthesis and D1 Receptor Agonism are Essential for Resolution of Experimental Lung Fibrosis
A. Haak, N. Caporarello, J. Meridew, K. Choi +1 more
2021The FASEB Journal0 citations
Semantic Scholar
Lineage Labelled Col1a2+ Fibroblasts Undergo Transient Expansion and Activation Followed by Spontaneous Reversion After Bleomycin Injury
Dakota L. Jones, J. Meridew, Q. Tan, N. Caporarello +3 more
20200 citations Open access
Semantic Scholar
Comparative Transcriptional Profiling of Lung Fibroblasts from Aged and Young Mice Following Lung Injury Reveals Signature of Sustained Pro-Fibrotic Activation
G. Ligresti, J. Meridew, Q. Tan, N. Caporarello +5 more
2019A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS0 citations
Semantic Scholar
Vascular Rarefaction and Loss of Endothelial Identity Accompanies Persistent Fibrosis in Bleomycin-injured Aged Mice
N. Caporarello, Aja Aravamudhan, J. Meridew, T. Qi +2 more
2019C60. VASCULAR BIOLOGY IN LUNG DISEASE0 citations
Semantic Scholar
Targeting TBK1 to Reduce Fibroblast Activation
Aja Aravamudhan, A. Haak, G. Ligresti, J. Meridew +4 more
2019C62. FIBROBLAST BIOLOGY0 citations
Semantic Scholar
Plasma-Derived Extracellular Vesicles Isolated from Young Mice During Fibrosis Resolution Exert Anti-Fibrotic Effect in Lung Fibroblasts
N. Caporarello, J. Meridew, K. R. Betageri, P. Link +2 more
TP107. TP107 PULMONARY FIBROSIS: MOLECULAR AND CELLULAR MECHANISMS0 citations Open access
Semantic Scholar
The Epigenetic Repressor CBX5 Drives Fibroblast Metabolic Reprograming and Lung Fibrogenesis
J. Lee, T. Pham, J. Guan, N. Caporarello +7 more
C9. C009 MODULATORS OF LUNG INJURY AND REPAIR0 citations Open access
Semantic Scholar
Targeting Aging-Induced PIM1 Kinase in Lung Fibroblasts to Promote Fibrosis Resolution
T. Pham, J. Lee, J. Guan, J. Meridew +8 more
TP116. TP116 PRECLINICAL THERAPEUTIC MODELS OF FIBROSIS0 citations Open access
Semantic Scholar

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