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A. Sawalha · SciRah

Researcher profile · Semantic Scholar

A. Sawalha

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A. Sawalha — researcher profile on SciRah

h-index: 63
Works: 232
Citations: 11K

Most-cited papers

COVID-19 and Autoimmune Diseases
Yu Liu, A. Sawalha, Qian-Jin Lu
2020Current Opinion in Rheumatology406 citations Open access
Semantic Scholar
Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients
A. Sawalha, Ming Zhao, P. Coit, Qian-Jin Lu
2020Clinical Immunology245 citations Open access
Semantic Scholar
COVID-19: A review of therapeutic strategies and vaccine candidates
V. Izda, M. Jeffries, A. Sawalha
2020Clinical Immunology208 citations Open access
Semantic Scholar
Monogenic Lupus: A Developing Paradigm of Disease
Jessie Alperin, L. Ortiz-Fernández, A. Sawalha
2018Frontiers in Immunology145 citations Open access
Semantic Scholar
Drug-induced lupus erythematosus: an update on drugs and mechanisms
Ye He, A. Sawalha
2018Current Opinion in Rheumatology139 citations Open access
Semantic Scholar
Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma
Pei-Suen Tsou, P. Campbell, M. A. Amin, P. Coit +4 more
2019Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
Clinical Treatment Options in Scleroderma: Recommendations and Comprehensive Review
Ming Zhao, Jiali Wu, Hai-Jing Wu, A. Sawalha +1 more
2021Clinical reviews in allergy and immunology79 citations
Semantic Scholar
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
M. Munz, C. Willenborg, G. Richter, Y. Jockel-Schneider +32 more
2018Human Molecular Genetics72 citations Open access
Semantic Scholar
Guideline for the diagnosis, treatment and long-term management of cutaneous lupus erythematosus.
Qian-Jin Lu, Hai Long, Steven Chow, S. Hidayat +31 more
2021Journal of Autoimmunity70 citations Open access
Semantic Scholar
Clinical value of DNA methylation markers in autoimmune rheumatic diseases
E. Ballestar, A. Sawalha, Qian-Jin Lu
2020Nature Reviews Rheumatology68 citations Open access
Semantic Scholar
Sex chromosome contributions to sex differences in multiple sclerosis susceptibility and progression
R. Voskuhl, A. Sawalha, Yuichiro Itoh
2018Multiple Sclerosis66 citations Open access
Semantic Scholar
Parent-of-origin differences in DNA methylation of X chromosome genes in T lymphocytes
L. Golden, Yuichiro Itoh, N. Itoh, S. Iyengar +5 more
2019Proceedings of the National Academy of Sciences of the United States of America65 citations Open access
Semantic Scholar
Shared epitope–aryl hydrocarbon receptor crosstalk underlies the mechanism of gene–environment interaction in autoimmune arthritis
Jia-Qi Fu, S. Nogueira, V. van Drongelen, P. Coit +4 more
2018Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
Semantic Scholar
Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice
Dallas M. Rohraff, Ye He, E. Farkash, Mark Schonfeld +2 more
2018bioRxiv61 citations Open access
Semantic Scholar
Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study.
L. Ortiz-Fernández, G. Saruhan-Direskeneli, F. Alibaz-Oner, S. Kaymaz-Tahra +67 more
2020American Journal of Human Genetics57 citations Open access
Semantic Scholar
Systemic lupus erythematosus as a genetic disease
Isaac T. W. Harley, A. Sawalha
2022Clinical Immunology50 citations Open access
Semantic Scholar
Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations
L. Ortiz-Fernández, A. Sawalha
2020Genes and Immunity50 citations Open access
Semantic Scholar
Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity.
M. Iris, Pei-Suen Tsou, A. Sawalha
2018Clinical Immunology50 citations Open access
Semantic Scholar
Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts
Ye He, Pei-Suen Tsou, D. Khanna, A. Sawalha
2018Annals of the Rheumatic Diseases48 citations Open access
Semantic Scholar
Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis
Souren Paul, M. Kaplan, D. Khanna, Preston M. McCourt +8 more
2022Nature Communications39 citations Open access
Semantic Scholar
The Role of Oxidative Stress in Epigenetic Changes Underlying Autoimmunity
Xiao-Qing Zheng, A. Sawalha
2021Antioxidants and Redox Signaling39 citations Open access
Semantic Scholar
Genetics of Behçet's Disease: Functional Genetic Analysis and Estimating Disease Heritability
L. Ortiz-Fernández, A. Sawalha
2021Frontiers in Medicine37 citations Open access
Semantic Scholar
Genome-wide DNA methylation analysis in ankylosing spondylitis identifies HLA-B*27 dependent and independent DNA methylation changes in whole blood.
P. Coit, Prashant Kaushik, L. Caplan, G. Kerr +4 more
2019Journal of Autoimmunity35 citations
Semantic Scholar
Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils
Emma M. B. Weeding, P. Coit, Srilakshmi Yalavarthi, M. Kaplan +2 more
2018Clinical Immunology35 citations Open access
Semantic Scholar
Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells
Shaylynn Miller, Pei-Suen Tsou, P. Coit, E. Gensterblum-Miller +5 more
2018bioRxiv35 citations Open access
Semantic Scholar
Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical Practice
Emma M. B. Weeding, A. Sawalha
2018Frontiers in Immunology34 citations Open access
Semantic Scholar
Takayasu arteritis risk locus in IL6 represses the anti-inflammatory gene GPNMB through chromatin looping and recruiting MEF2–HDAC complex
X. Kong, A. Sawalha
2019Annals of the Rheumatic Diseases30 citations Open access
Semantic Scholar
Sex-specific analysis in Behçet’s disease reveals higher genetic risk in male patients
Gun-Jo Yun, Lourdes Ortiz Fernández, P. Coit, V. Yılmaz +28 more
2022Journal of Autoimmunity29 citations Open access
Semantic Scholar
Coronavirus Disease-2019: Implication for the care and management of patients with systemic lupus erythematosus.
A. Sawalha, S. Manzi
2020European Journal of Rheumatology29 citations Open access
Semantic Scholar
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis
L. Ortiz-Fernández, F. Carmona, R. López-Mejías, M. González-Escribano +7 more
2018Annals of the Rheumatic Diseases29 citations Open access
Semantic Scholar
Management of Behçet's disease
F. Alibaz-Oner, A. Sawalha, H. Direşkeneli
2018Current Opinion in Rheumatology29 citations
Semantic Scholar
An update on the role of epigenetics in systemic vasculitis
P. Coit, H. Direşkeneli, A. Sawalha
2018Current Opinion in Rheumatology28 citations Open access
Semantic Scholar
Post-GWAS functional analysis identifies CUX1 as a regulator of p16INK4a and cellular senescence
D. Jiang, Wei Sun, Ting Wu, Mei-Juan Zou +16 more
2022Nature Aging26 citations Open access
Semantic Scholar
ChatGPT, et al … Artificial Intelligence, Authorship, and Medical Publishing
Daniel H. Solomon, K. Allen, Patricia Katz, A. Sawalha +1 more
2023ACR Open Rheumatology24 citations Open access
Semantic Scholar
Increased Expression of EZH2 Is Mediated by Higher Glycolysis and mTORC1 Activation in Lupus CD4+ T Cells
Xiao-Qing Zheng, Pei-Suen Tsou, A. Sawalha
2020Immunometabolism24 citations Open access
Semantic Scholar
Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma
S. Vichaikul, Mikel Gurrea-Rubio, M. A. Amin, P. Campbell +15 more
2020bioRxiv23 citations Open access
Semantic Scholar
Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs
Wen-Xia Wang, S. Bale, Jun Wei, B. Yalavarthi +20 more
2022Nature Communications21 citations Open access
Semantic Scholar
The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope
Bruna Miglioranza Scavuzzi, V. van Drongelen, Bhavneet Kaur, Jennifer Fox +8 more
2022Communications Biology21 citations Open access
Semantic Scholar
Genome-wide reduction in chromatin accessibility and unique transcription factor footprints in endothelial cells and fibroblasts in scleroderma skin
Pei-Suen Tsou, Pamela J. Palisoc, Mustafa Ali, D. Khanna +1 more
2020medRxiv21 citations Open access
Semantic Scholar
Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma
Pei-Suen Tsou, D. Khanna, A. Sawalha
2019Arthritis & Rheumatology21 citations Open access
Semantic Scholar
HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization
V. van Drongelen, B. Scavuzzi, S. Nogueira, F. Miller +2 more
2021Scientific Reports20 citations Open access
Semantic Scholar
Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis
Ilayda Altinönder, M. Kaya, S. Yentür, A. Çakar +6 more
2024Journal of Neuroinflammation19 citations Open access
Semantic Scholar
Novel transcriptional activity and extensive allelic imbalance in the human MHC region
Elizabeth Gensterblum, Weisheng Wu, A. Sawalha
2017Journal of Immunology19 citations Open access
Semantic Scholar
Genetics of Antiphospholipid Syndrome
L. Ortiz-Fernández, A. Sawalha
2019Current Rheumatology Reports18 citations
Semantic Scholar
SARS-CoV-2 and Systemic Lupus Erythematosus
A. Thanou, A. Sawalha
2021Current Rheumatology Reports17 citations Open access
Semantic Scholar
Identification of new risk loci shared across systemic vasculitides points towards potential target genes for drug repurposing
L. Ortiz-Fernández, E. Carmona, M. Kerick, P. Lyons +21 more
2023Annals of the Rheumatic Diseases16 citations Open access
Semantic Scholar
Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study
D. González-Serna, E. López-Isac, N. Yılmaz, F. Gharibdoost +12 more
2018Rheumatology16 citations Open access
Semantic Scholar
Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome
Ajay Tambralli, Alyssa Harbaugh, S. NaveenKumar, Megan D. Radyk +16 more
2024Journal of Clinical Investigation15 citations Open access
Semantic Scholar
Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature
P. Coit, Xiavan Roopnarinesingh, L. Ortiz-Fernández, K. Maksimowicz-McKinnon +5 more
2022Annals of the Rheumatic Diseases14 citations Open access
Semantic Scholar
Ezh2 knockout in B cells impairs plasmablast differentiation and ameliorates lupus-like disease in MRL/lpr mice
Xiao-long Zheng, M. Dozmorov, Colleen E. Strohlein, S. Bastacky +1 more
2022bioRxiv12 citations Open access
Semantic Scholar

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