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J. Bigay · SciRah

Researcher profile · Semantic Scholar

J. Bigay

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J. Bigay — researcher profile on SciRah

h-index: 27
Works: 52
Citations: 4,961

Most-cited papers

A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP.
B. Mesmin, J. Bigay, Joachim Moser von Filseck, S. Lacas-Gervais +2 more
2013Cell726 citations Open access
Semantic Scholar
Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity.
J. Bigay, B. Antonny
2012Developmental Cell497 citations
Semantic Scholar
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif
J. Bigay, J. Casella, Guillaume Drin, B. Mesmin +1 more
2005EMBO Journal368 citations Open access
Semantic Scholar
Fluoroaluminates activate transducin‐GDP by mimicking the γ‐phosphate of GTP in its binding site
J. Bigay, P. Deterre, C. Pfister, M. Chabre
1985351 citations Open access
Semantic Scholar
Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature
J. Bigay, P. Gounon, S. Robineau, B. Antonny
2003Nature338 citations
Semantic Scholar
Fluoride complexes of aluminium or beryllium act on G‐proteins as reversibly bound analogues of the gamma phosphate of GTP.
J. Bigay, Philippe Deterre, C. Pfister, M. Chabre
1987EMBO Journal338 citations Open access
Semantic Scholar
SUPPLEMENTAL INFORMATION TO: Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein (OSBP)
J. Strating, Lonneke van der Linden, L. Albulescu, J. Bigay +19 more
2014224 citations
Semantic Scholar
Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP
B. Mesmin, J. Bigay, J. Polidori, Denisa Jamecna +2 more
2017EMBO Journal216 citations Open access
Semantic Scholar
cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits.
Philippe Deterre, J. Bigay, Frederique Forquet, M. Robert +1 more
1988Proceedings of the National Academy of Sciences of the United States of America214 citations Open access
Semantic Scholar
α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding
I. M. Pranke, V. Morello, J. Bigay, K. Gibson +3 more
2011Journal of Cell Biology203 citations Open access
Semantic Scholar
Role of Protein-Phospholipid Interactions in the Activation of ARF1 by the Guanine Nucleotide Exchange Factor Arno*
S. Paris, S. Béraud-Dufour, S. Robineau, J. Bigay +3 more
1997Journal of Biological Chemistry164 citations Open access
Semantic Scholar
Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers.
F. Duprat, Florian Lesage, Eric Guillemare, Michel Fink +5 more
1995Biochemical and Biophysical Research Communications - BBRC156 citations
Semantic Scholar
The Oxysterol-Binding Protein Cycle: Burning Off PI(4)P to Transport Cholesterol.
B. Antonny, J. Bigay, B. Mesmin
2018Annual Review of Biochemistry148 citations
Semantic Scholar
Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature.
B. Mesmin, Guillaume Drin, S. Levi, M. Rawet +3 more
2007Biochemistry123 citations
Semantic Scholar
Roles of lipid modifications of transducin subunits in their GDP-dependent association and membrane binding.
J. Bigay, E. Faurobert, M. Franco, M. Chabre
1994Biochemistry83 citations
Semantic Scholar
Activation of retinal rod cyclic GMP‐phosphodiesterase by transducin: Characterization of the complex formed by phosphodiesterase inhibitor and transducin α‐subunit
P. Deterre, J. Bigay, M. Robert, C. Pfister +2 more
1986Proteins: Structure, Function, and Bioinformatics72 citations
Semantic Scholar
An Intrinsically Disordered Region in OSBP Acts as an Entropic Barrier to Control Protein Dynamics and Orientation at Membrane Contact Sites.
Denisa Jamecna, J. Polidori, B. Mesmin, Manuela Dezi +3 more
2019Developmental Cell61 citations Open access
Semantic Scholar
The mechanism of aluminum-independent G-protein activation by fluoride and magnesium. 31P NMR spectroscopy and fluorescence kinetic studies.
Bruno Antonny, M. Sukumar, J. Bigay, M. Chabre +1 more
1993Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Fluoroaluminates activate transducin-GDP by mimicking the gamma-phosphate of GTP in its binding site.
J. Bigay, Philippe Deterre, C. Pfister, M. Chabre
1985FEBS Letters58 citations
Semantic Scholar
Uncovering oxysterol‐binding protein (OSBP) as a target of the anti‐enteroviral compound TTP‐8307
L. Albulescu, J. Bigay, B. Biswas, Marion Weber-Boyvat +8 more
2017Antiviral Research53 citations Open access
Semantic Scholar
Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat.
Lena Kliouchnikov, J. Bigay, B. Mesmin, Anna Parnis +4 more
2008Molecular Biology of the Cell51 citations Open access
Semantic Scholar
Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites
E. de la Mora, Manuela Dezi, Aurélie Di Cicco, J. Bigay +7 more
2020Nature Communications48 citations Open access
Semantic Scholar
G-protein βγ Subunits Mediate Specific Phosphorylation of the Protein-tyrosine Phosphatase SH-PTP1 Induced by Lysophosphatidic Acid*
F. Gaits, Ruo-Ya Li, J. Bigay, A. Ragab +2 more
1996Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation.
B. Antonny, J. Bigay, J. Casella, Guillaume Drin +2 more
2005Biochemical Society Transactions40 citations
Semantic Scholar
Real-time assays for the assembly-disassembly cycle of COP coats on liposomes of defined size.
J. Bigay, B. Antonny
2005Methods in Enzymology38 citations
Semantic Scholar
Saturated Fatty Acids Alter the Late Secretory Pathway by Modulating Membrane Properties
Laurie-Anne Payet, Ludovic Pineau, Ellen C. R. Snyder, J. Colas +8 more
2013Traffic : the International Journal of Intracellular Transport32 citations Open access
Semantic Scholar
A novel magnesium‐dependent mechanism for the activation of transducin by fluoride
B. Antonny, J. Bigay, M. Chabre
1990FEBS Letters28 citations Open access
Semantic Scholar
VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites.
Mélody Subra, Manuela Dezi, J. Bigay, Sandra Lacas-Gervais +11 more
2023Developmental Cell26 citations Open access
Semantic Scholar
Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitor
T. Péresse, Dávid Kovács, Mélody Subra, J. Bigay +12 more
2020Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Guanine nucleotides and magnesium dependence of the association states of the subunits of transducin
P. Deterre, J. Bigay, C. Pfister, M. Chabre
1984FEBS Letters24 citations Open access
Semantic Scholar
Functional modifications of transducin induced by cholera or pertussis-toxin-catalyzed ADP-ribosylation.
Frédéric Bornancin, M. Franco, J. Bigay, M. Chabre
1992European Journal of Biochemistry23 citations Open access
Semantic Scholar
Poliovirus Evolution toward Independence from the Phosphatidylinositol-4 Kinase III β/Oxysterol-Binding Protein Family I Pathway.
M. Arita, J. Bigay
2019ACS Infectious Diseases20 citations Open access
Semantic Scholar
Building lipid 'PIPelines' throughout the cell by ORP/Osh proteins.
Joachim Moser von Filseck, B. Mesmin, J. Bigay, B. Antonny +1 more
2014Biochemical Society Transactions20 citations
Semantic Scholar
Purification of transducin.
J. Bigay, M. Chabre
1994Methods in Enzymology17 citations
Semantic Scholar
Tissue expression and phylogenetic appearance of the β and γ subunits of GTP binding proteins
Yves Audigier, C. Pantaloni, J. Bigay, Philippe Deterre +2 more
198517 citations
Semantic Scholar
Visual signal transduction: the cycle of transducin shuttling between rhodopsin and cGMP phosphodiesterase.
M. Chabre, J. Bigay, F. Bruckert, F. Bornancin +3 more
1988Cold Spring Harbor Symposia on Quantitative Biology14 citations
Semantic Scholar
VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites
Mélody Subra, Manuela Dezi, J. Bigay, S. Lacas-Gervais +11 more
2022bioRxiv13 citations Open access
Semantic Scholar
The retinal phototransduction process: enzymatic cascade and regulation.
Philippe Deterre, C. Pfister, J. Bigay, M. Chabre
1987Biochimie9 citations
Semantic Scholar
Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein.
Gwenaëlle Jézéquel, Céline Rampal, Carole Guimard, Dávid Kovács +14 more
2023Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
[34] Purification of Tβγ subunit of transducin
J. Bigay, M. Chabre
19947 citations
Semantic Scholar
[Regulation of vesicular transport by membrane curvature].
Guillaume Drin, J. Bigay, B. Antonny
2009Medecine sciences : M/S2 citations Open access
Semantic Scholar
Tissue expression and phylogenetic appearance of the beta and gamma subunits of GTP binding proteins.
Y. Audigier, C. Pantaloni, J. Bigay, P. Deterre +2 more
1985FEBS Letters2 citations
Semantic Scholar
[A lipid exchange market : vectorial cholesterol transport by the protein OSBP].
J. Bigay, B. Mesmin, B. Antonny
2020Medecine sciences : M/S1 citations Open access
Semantic Scholar
Purification of T beta gamma subunit of transducin.
J. Bigay, M. Chabre
1994Methods in Enzymology1 citations
Semantic Scholar
Fluoride complexes ofaluminium orberyllium acton G-proteins as reversibly boundanalogues ofthe-yphosphate ofGTP
J. Bigay, P. Deterre, C. Pfister
19871 citations
Semantic Scholar
Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor
T. Péresse, Dávid Kovács, Mélody Subra, J. Bigay +12 more
2019bioRxiv0 citations Open access
Semantic Scholar
Control of PI4P turnover by endogenous OSBP for fast cholesterol transport at membrane contact sites
B. Mesmin, J. Bigay, J. Polidori, S. Lacas-Gervais +1 more
2017The FASEB Journal0 citations Open access
Semantic Scholar
Control of Membrane Remodeling at the Golgi Through Sensors of Membrane Curvature: The ALPS Motif
B. Antonny, J. Bigay, J. Casella, Guillaume Drin +4 more
20090 citations Open access
Semantic Scholar
Activation of Transducin by Aluminum or Beryllium Fluoride Complexes
J. Bigay
19890 citations
Semantic Scholar
Activation du systeme de la phototransduction par les complexes fluoroaluminates : modele d'interaction du complexe alf#-#4, analogue de po#3#-#4, avec les proteines de couplage gtp-dependantes
J. Bigay
19880 citations
Semantic Scholar

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B. Antonny×25
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M. Chabre×11
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Guillaume Drin×8
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Philippe Deterre×6

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