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Derick Han · SciRah

Researcher profile · Semantic Scholar

Derick Han

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Derick Han — researcher profile on SciRah

h-index: 42
Works: 75
Citations: 8,322

Most-cited papers

Voltage-dependent Anion Channels Control the Release of the Superoxide Anion from Mitochondria to Cytosol*
Derick Han, F. Antunes, R. Canali, D. Rettori +1 more
2003Journal of Biological Chemistry704 citations Open access
Semantic Scholar
Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol.
E. Serbinova, V. Kagan, Derick Han, L. Packer
1991Free Radical Biology & Medicine663 citations
Semantic Scholar
Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space.
Derick Han, Everett Williams, E. Cadenas
2001Biochemical Journal621 citations Open access
Semantic Scholar
Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury*
Naoko Hanawa, M. Shinohara, B. Saberi, W. Gaarde +2 more
2008Journal of Biological Chemistry520 citations Open access
Semantic Scholar
c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
Basuki K Gunawan, Zhang-Xu Liu, Derick Han, Naoko Hanawa +2 more
2006Gastroenterology471 citations
Semantic Scholar
Neutrophil depletion protects against murine acetaminophen hepatotoxicity
Zhang-Xu Liu, Derick Han, Basuki K Gunawan, N. Kaplowitz
2006Hepatology323 citations
Semantic Scholar
Mechanisms of liver injury. III. Role of glutathione redox status in liver injury.
Derick Han, Naoko Hanawa, B. Saberi, N. Kaplowitz
2006American Journal of Physiology - Gastrointestinal and Liver Physiology298 citations
Semantic Scholar
Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide1–42- and Lipopolysaccharide-Activated Microglia
Zhonghua Xie, Min Wei, T. Morgan, P. Fabrizio +3 more
2002Journal of Neuroscience271 citations Open access
Semantic Scholar
Effect of glutathione depletion on sites and topology of superoxide and hydrogen peroxide production in mitochondria.
Derick Han, R. Canali, D. Rettori, N. Kaplowitz
2003Molecular Pharmacology217 citations
Semantic Scholar
Vitamin E recycling in human erythrocyte membranes.
A. Constantinescu, Derick Han, L. Packer
1993Journal of Biological Chemistry213 citations Open access
Semantic Scholar
Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat.
R. Sokol, J. Mckim, Meghan Goff, S. Ruyle +4 more
1998Gastroenterology206 citations Open access
Semantic Scholar
Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria
Derick Han, Lily Dara, S. Win, T. Than +4 more
2013TIPS - Trends in Pharmacological Sciences193 citations Open access
Semantic Scholar
c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice*
S. Win, T. Than, Derick Han, L. Petrovic +1 more
2011Journal of Biological Chemistry193 citations Open access
Semantic Scholar
Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress.
Derick Han, Katsuhiko Matsumaru, D. Rettori, N. Kaplowitz
2004Biochemical Pharmacology189 citations
Semantic Scholar
Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates*
J. Garcia, Derick Han, H. Sancheti, Li-peng Yap +2 more
2010Journal of Biological Chemistry178 citations Open access
Semantic Scholar
Redox Regulation of Tumor Necrosis Factor Signaling
Derick Han, M. Ybanez, S. Ahmadi, K. Yeh +1 more
2009Antioxidants and Redox Signaling175 citations Open access
Semantic Scholar
Receptor Interacting Protein Kinase-1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis
Lily Dara, H. Johnson, Jo Suda, S. Win +3 more
2015Hepatology168 citations Open access
Semantic Scholar
Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione.
Derick Han, R. Canali, J. Garcia, R. Aguilera +2 more
2005Biochemistry160 citations
Semantic Scholar
Relative contributions of heart mitochondria glutathione peroxidase and catalase to H(2)O(2) detoxification in in vivo conditions.
F. Antunes, Derick Han, E. Cadenas
2002Free Radical Biology & Medicine151 citations
Semantic Scholar
Dose-Response Effects of Acute Ultraviolet Irradiation on Antioxidants and Molecular Markers of Oxidation in Murine Epidermis and Dermis
Y. Shindo, E. Witt, Derick Han, L. Packer
1994146 citations Open access
Semantic Scholar
Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants.
Derick Han, C. Sen, Sashwati Roy, Michael S. Kobayashi +2 more
1997American Journal of Physiology. Regulatory Integrative and Comparative Physiology141 citations
Semantic Scholar
Signal transduction pathways involved in drug-induced liver injury.
Derick Han, M. Shinohara, M. Ybanez, B. Saberi +1 more
2010Handbook of Experimental Pharmacology125 citations
Semantic Scholar
Generation of reactive oxygen species by mitochondria
E. Cadenas, Derick Han
2007124 citations
Semantic Scholar
Cytosolic and Mitochondrial Systems for NADH- and NADPH-dependent Reduction of α-Lipoic Acid
N. Haramaki, Derick Han, G. Handelman, H. Tritschler +1 more
1997123 citations
Semantic Scholar
c‐Jun N‐terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons
Qiong-Qiong Zhou, P. Lam, Derick Han, E. Cadenas
2007Journal of Neurochemistry112 citations
Semantic Scholar
Silencing Glycogen Synthase Kinase-3β Inhibits Acetaminophen Hepatotoxicity and Attenuates JNK Activation and Loss of Glutamate Cysteine Ligase and Myeloid Cell Leukemia Sequence 1*
M. Shinohara, M. Ybanez, S. Win, T. Than +4 more
2010Journal of Biological Chemistry110 citations Open access
Semantic Scholar
Regulation of Cellular Thiols in Human Lymphocytes by α-Lipoic Acid: A Flow Cytometric Analysis
C. Sen, Sashwati Roy, Derick Han, L. Packer
1997104 citations
Semantic Scholar
Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis.
Derick Han, Naoko Hanawa, B. Saberi, N. Kaplowitz
2006Free Radical Biology & Medicine99 citations
Semantic Scholar
Dynamic Adaptation of Liver Mitochondria to Chronic Alcohol Feeding in Mice
Derick Han, M. Ybanez, H. Johnson, J. N. McDonald +9 more
2012Journal of Biological Chemistry90 citations Open access
Semantic Scholar
Activation of C-Jun-N-Terminal Kinase and Decline of Mitochondrial Pyruvate Dehydrogenase Activity during Brain Aging
Qiong-Qiong Zhou, P. Lam, Derick Han, E. Cadenas
2009FEBS Letters89 citations Open access
Semantic Scholar
Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through JNK dependent and independent signaling pathways
B. Saberi, M. Ybanez, H. Johnson, W. Gaarde +2 more
2014Hepatology87 citations Open access
Semantic Scholar
Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria.
Dean P. Jones, J. Lemasters, Derick Han, U. Boelsterli +1 more
2010Molecular Interventions84 citations Open access
Semantic Scholar
Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity
Michael S. Kobayashi, Derick Han, L. Packer
2000Free radical research82 citations
Semantic Scholar
Elucidation of antioxidant activity of α-lipoic acid toward hydroxyl radical
S. Matsugo, Liang-Jun Yan, Derick Han, H. Trischler +1 more
199571 citations
Semantic Scholar
Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis.
P. Iñarrea, H. Moini, Derick Han, D. Rettori +4 more
2007Biochemical Journal67 citations Open access
Semantic Scholar
Respiratory Substrates Regulate S-Nitrosylation of Mitochondrial Proteins through a Thiol-Dependent Pathway
A. Chang, H. Sancheti, J. Garcia, N. Kaplowitz +2 more
2014Chemical Research in Toxicology64 citations Open access
Semantic Scholar
Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes.
B. Saberi, M. Shinohara, M. Ybanez, Naoko Hanawa +3 more
2008American Journal of Physiology - Cell Physiology62 citations Open access
Semantic Scholar
Redox activation of mitochondrial intermembrane space Cu,Zn-superoxide dismutase.
P. Iñarrea, H. Moini, D. Rettori, Derick Han +5 more
2005Biochemical Journal59 citations Open access
Semantic Scholar
Determination of GSH, GSSG, and GSNO Using HPLC with Electrochemical Detection
Li-peng Yap, H. Sancheti, M. Ybanez, J. Garcia +2 more
2010Methods in Enzymology58 citations Open access
Semantic Scholar
THE ENERGY-REDOX AXIS IN AGING AND AGE-RELATED NEURODEGENERATION
Li-peng Yap, J. Garcia, Derick Han, E. Cadenas
2009Advanced Drug Delivery Reviews57 citations Open access
Semantic Scholar
Alcohol as a Modifiable Risk Factor for Alzheimer’s Disease—Evidence from Experimental Studies
D. V. Chandrashekar, R. Steinberg, Derick Han, Rachita K. Sumbria
2023International Journal of Molecular Sciences46 citations Open access
Semantic Scholar
Mitochondrial remodeling in the liver following chronic alcohol feeding to rats
Derick Han, H. Johnson, Madhuri P. Rao, Gary Martin +7 more
2016Free Radical Biology & Medicine46 citations Open access
Semantic Scholar
[29] Analysis of reduced and oxidized lipoic acid in biological samples by high-performance liquid chromatography
Derick Han, G. Handelman, L. Packer
199540 citations
Semantic Scholar
Mitochondrial damage by nitric oxide is potentiated by dopamine in PC12 cells.
F. Antunes, Derick Han, D. Rettori, E. Cadenas
2002Biochimica et Biophysica Acta39 citations Open access
Semantic Scholar
Role of nitric oxide-mediated glutathionylation in neuronal function: potential regulation of energy utilization
Li-peng Yap, J. Garcia, Derick Han, E. Cadenas
2010Biochemical Journal34 citations Open access
Semantic Scholar
How to protect against acetaminophen: don't ask for JUNK.
N. Kaplowitz, M. Shinohara, Zhang-Xu Liu, Derick Han
2008Gastroenterology28 citations Open access
Semantic Scholar
Mitochondrial superoxide anion production and release into intermembrane space.
Derick Han, F. Antunes, Francesca Daneri, E. Cadenas
2002Methods in Enzymology28 citations
Semantic Scholar
Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β
J. Garcia, Rudy Chang, R. Steinberg, A. Arce +12 more
2022Frontiers in Physiology26 citations Open access
Semantic Scholar
Part VII • Chapter 17 – Oxidative stress indices: analytical aspects and significance
Derick Han, Sonia Loukianoff, L. McLaughlin
200026 citations
Semantic Scholar
Redox Regulation of NF-κB: From Basic to Clinical Research
F. Antunes, Derick Han
2009Antioxidants and Redox Signaling23 citations
Semantic Scholar

Frequent co-authors

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N. Kaplowitz×22
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N. Kaplowitz — researcher profile on SciRah
E. Cadenas×19
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E. Cadenas — researcher profile on SciRah
L. Packer×10
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L. Packer — researcher profile on SciRah
J. Garcia×7
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J. Garcia — researcher profile on SciRah

×7

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M. Ybanez — researcher profile on SciRah

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D. Rettori — researcher profile on SciRah

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B. Saberi — researcher profile on SciRah

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W. Gaarde — researcher profile on SciRah

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F. Antunes — researcher profile on SciRah

Naoko Hanawa×5

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Naoko Hanawa — researcher profile on SciRah

M. Shinohara×5

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M. Shinohara — researcher profile on SciRah

Zhang-Xu Liu×5

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Zhang-Xu Liu — researcher profile on SciRah