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Richard L. Dunbar · SciRah

Researcher profile · Semantic Scholar

Richard L. Dunbar

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Richard L. Dunbar — researcher profile on SciRah

h-index: 23
Works: 89
Citations: 2,674

Most-cited papers

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
F. Dewey, V. Gusarova, Richard L. Dunbar, C. O'Dushlaine +53 more
2017New England Journal of Medicine775 citations Open access
Semantic Scholar
Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism
A. Wolska, Richard L. Dunbar, L. Freeman, M. Ueda +3 more
2017Atherosclerosis197 citations Open access
Semantic Scholar
Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia
Z. Ahmad, P. Banerjee, S. Hamon, Kuo-Chen Chan +7 more
2019Circulation193 citations Open access
Semantic Scholar
patient-oriented and epidemiological research Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients
L. Bloedon, Richard L. Dunbar, Danielle Duffy, Paula Pinell-Salles +6 more
2008193 citations
Semantic Scholar
Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes
A. Digenio, Richard L. Dunbar, V. Alexander, M. Hompesch +9 more
2016Diabetes Care156 citations
Semantic Scholar
Niacin Lipid Efficacy Is Independent of Both the Niacin Receptor GPR109A and Free Fatty Acid Suppression
Brett Lauring, Andrew K. P. Taggart, J. Tata, Richard L. Dunbar +29 more
2012Science Translational Medicine126 citations
Semantic Scholar
A highly bioavailable omega-3 free fatty acid formulation improves the cardiovascular risk profile in high-risk, statin-treated patients with residual hypertriglyceridemia (the ESPRIT trial).
K. Maki, D. Orloff, S. Nicholls, Richard L. Dunbar +5 more
2013Clinical Therapeutics111 citations
Semantic Scholar
Intraindividual variability of C-reactive protein: The Multi-Ethnic Study of Atherosclerosis
Emil M. deGoma, B. French, Richard L. Dunbar, M. Allison +2 more
2012Atherosclerosis71 citations Open access
Semantic Scholar
Oral Apolipoprotein A‐I Mimetic D‐4F Lowers HDL‐Inflammatory Index in High‐Risk Patients: A First‐in‐Human Multiple‐Dose, Randomized Controlled Trial
Richard L. Dunbar, R. Movva, L. Bloedon, Danielle Duffy +4 more
2017Clinical and Translational Science62 citations Open access
Semantic Scholar
Effects of niacin, statin, and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 levels in patients with dyslipidemia.
A. Khera, Arman Qamar, M. Reilly, Richard L. Dunbar +1 more
2015American Journal of Cardiology57 citations
Semantic Scholar
Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects.
J. Millar, G. Reyes-Soffer, Patricia A. Jumes, Richard L. Dunbar +17 more
2015Journal of Clinical Investigation55 citations Open access
Semantic Scholar
Effects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial
Richard L. Dunbar, S. Nicholls, K. Maki, E. Roth +5 more
2015Lipids in Health and Disease50 citations Open access
Semantic Scholar
Inhibition of Angiopoietin-Like Protein 3 With Evinacumab in Subjects With High and Severe Hypertriglyceridemia.
Z. Ahmad, R. Pordy, D. Rader, D. Gaudet +6 more
2021Journal of the American College of Cardiology49 citations Open access
Semantic Scholar
Discordance between non-HDL-cholesterol and LDL-particle measurements: Results from the Multi-Ethnic Study of Atherosclerosis
Emil M. deGoma, M. D. Davis, Richard L. Dunbar, E. Mohler +2 more
2013Atherosclerosis44 citations Open access
Semantic Scholar
A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency With Severe Triglyceridemia and Pancreatitis
M. Ueda, Richard L. Dunbar, A. Wolska, Tracey U. Sikora +14 more
2017Journal of Clinical Endocrinology and Metabolism40 citations Open access
Semantic Scholar
The potent and selective PPAR-α agonist LY518674 upregulates both apoA-I production and catabolism in human subjects with the metabolic syndrome
J. Millar, Danielle Duffy, Ramprasad Gadi, L. Bloedon +10 more
2008Arteriosclerosis, Thrombosis and Vascular Biology40 citations Open access
Semantic Scholar
Seeing red: flushing out instigators of niacin-associated skin toxicity.
Richard L. Dunbar, J. Gelfand
2010Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Pharmacokinetic Interactions of the Microsomal Triglyceride Transfer Protein Inhibitor, Lomitapide, with Drugs Commonly Used in the Management of Hypercholesterolemia
S. Tuteja, Danielle Duffy, Richard L. Dunbar, R. Movva +3 more
2014Pharmacotherapy37 citations
Semantic Scholar
CETP inhibition with Anacetrapib Decreases Fractional Clearance Rates of HDL Apolipoprotein A-I and Plasma CETP
G. Reyes-Soffer, J. Millar, C. Ngai, Patricia A. Jumes +18 more
2016Arteriosclerosis, Thrombosis and Vascular Biology35 citations Open access
Semantic Scholar
Differences in absolute risk of cardiovascular events using risk-refinement tests: A systematic analysis of four cardiovascular risk equations
Emil M. deGoma, Richard L. Dunbar, Douglas Jacoby, B. French
2012Atherosclerosis26 citations Open access
Semantic Scholar
Demystifying triglycerides: a practical approach for the clinician.
Richard L. Dunbar, D. Rader
2005Cleveland Clinic journal of medicine25 citations
Semantic Scholar
Effects of Extended Release Niacin added to Simvastatin/Ezetemibe on Glucose and Insulin values in AIM HIGH
R. Goldberg, V. Bittner, Richard L. Dunbar, J. Fleg +9 more
2016American Journal of Medicine24 citations Open access
Semantic Scholar
Extended-Release Niacin Acutely Suppresses Postprandial Triglyceridemia
M. Usman, Arman Qamar, Ramprasad Gadi, S. Lilly +6 more
2012American Journal of Medicine24 citations Open access
Semantic Scholar
Niacin Alternatives for Dyslipidemia: Fool’s Gold or Gold Mine? Part II: Novel Niacin Mimetics
Harsh Goel, Richard L. Dunbar
2016Current Atherosclerosis Reports23 citations Open access
Semantic Scholar
A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans[S]
M. Cuchel, A. Raper, D. Conlon, D. Pryma +19 more
2017Journal of Lipid Research22 citations Open access
Semantic Scholar
Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E
John S. Millar, Michael E. Lassman, Tiffany Thomas, R. Ramakrishnan +17 more
2017Journal of Lipid Research21 citations Open access
Semantic Scholar
Abrogation of postprandial triglyceridemia with dual PPAR α/γ agonist in type 2 diabetes mellitus: a randomized, placebo-controlled study
A. Rastogi, Richard L. Dunbar, H. Thacker, J. Bhatt +2 more
2020Acta Diabetologica18 citations
Semantic Scholar
Niacin Alternatives for Dyslipidemia: Fool’s Gold or Gold Mine? Part I: Alternative Niacin Regimens
Richard L. Dunbar, Harsh Goel
2016Current Atherosclerosis Reports14 citations Open access
Semantic Scholar
Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin
S. Tuteja, L. Qu, M. Vujkovic, Richard L. Dunbar +3 more
2018Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease13 citations Open access
Semantic Scholar
Genetic coding variants in the niacin receptor, hydroxyl-carboxylic acid receptor 2 (HCAR2), and response to niacin therapy
S. Tuteja, Lu Wang, Richard L. Dunbar, Jin-Bo Chen +5 more
2017Pharmacogenetics & Genomics13 citations Open access
Semantic Scholar
Could Exercise Metabolomics Pave the Way for Gymnomimetics?
Megan F. Burke, Richard L. Dunbar, D. Rader
2010Science Translational Medicine13 citations
Semantic Scholar
Estimated Atherosclerotic Cardiovascular Disease Risk Score: An Automated Decision Aid for Statin Therapy.
M. Sampson, A. Wolska, M. Amar, M. Ueda +3 more
2022Clinical Chemistry9 citations Open access
Semantic Scholar
Omega-3 fatty acid exposure with a low-fat diet in patients with past hypertriglyceridemia-induced acute pancreatitis; an exploratory, randomized, open-label crossover study
Richard L. Dunbar, D. Gaudet, M. Davidson, M. Rensfeldt +4 more
2020Lipids in Health and Disease8 citations Open access
Semantic Scholar
Abstract 19030: Apolipoprotein C-III is Significantly Reduced by Prescription Omega-3 Free Fatty Acids (Epanova) in Patients with Severe Hypertriglyceridemia and Changes Correlate with Increases in LDL-C: A Sub-analysis of the EVOLVE trial
D. Rader, Richard L. Dunbar, K. Maki, T. A. Jacobson +2 more
2012Circulation8 citations
Semantic Scholar
Experimental Therapeutics for Challenging Clinical Care of a Patient with an Extremely Rare Homozygous APOC2 Mutation
M. Ueda, A. Wolska, Frances M. Burke, Maria Escobar +6 more
2020Case Reports in Endocrinology7 citations Open access
Semantic Scholar
PHASE 1 SINGLE AND MULTIPLE ASCENDING DOSE STUDY OF CAT-2003, A NOVEL ACTIVATOR OF LIPOPROTEIN LIPASE, DEMONSTRATES REDUCTIONS IN POSTPRANDIAL TRIGLYCERIDES
J. Donovan, Richard L. Dunbar, L. Biernat, Douglas K. Logan +3 more
20147 citations Open access
Semantic Scholar
Abstract 1496: Oral Administration of the Apolipoprotein A-I Mimetic Peptide D-4F in Humans with CHD Improves HDL Anti-Inflammatory Function After a Single Dose
L. Bloedon, Richard L. Dunbar, Danielle Duffy, P. Pinell-Salles +3 more
20067 citations
Semantic Scholar
Familial Chylomicronemia Syndrome With a Novel Homozygous LPL Mutation Identified in Three Siblings in Their 50s
M. Ueda, Frances M. Burke, A. Remaley, R. Hegele +2 more
2019Annals of Internal Medicine6 citations
Semantic Scholar
Current drug options for raising HDL cholesterol
Richard L. Dunbar, D. Rader
2005Current Treatment Options in Cardiovascular Medicine6 citations
Semantic Scholar
The unsung perils of peripheral arterial disease: a malady in search of a patient.
Richard L. Dunbar, E. Mohler
2005Preventive Cardiology6 citations Open access
Semantic Scholar
Measuring niacin-associated skin toxicity (NASTy) stigmata along with symptoms to aid development of niacin mimetics[S]
Richard L. Dunbar, Harsh Goel, S. Tuteja, Wen-Liang Song +6 more
2017Journal of Lipid Research5 citations Open access
Semantic Scholar
Abstract 439: Niacin Does Not Accelerate Reverse Cholesterol Transport in Man
Richard L. Dunbar, M. Cuchel, J. Millar, A. Baer +5 more
20135 citations
Semantic Scholar
Slaying the metabolic syndrome. Are we battling the Hydra or the Chimera?
Richard L. Dunbar, Daniel J. Rader
2004Minerva Endocrinologica5 citations
Semantic Scholar
Impact of high doses of the MTP-Inhibitor, AEGR-733, on the single dose Pharmacokinetics of Atorvastatin and Rosuvastatin
Richard L. Dunbar, L. Bloedon, Ramprasad Gadi, Danielle Duffy +4 more
20074 citations
Semantic Scholar
A retrospective analysis of clinical use of alirocumab in lipoprotein apheresis patients.
A. Goldberg, Richard L. Dunbar, L. Hemphill, Stephan P. Babirak +7 more
2020Journal of Clinical Lipidology3 citations Open access
Semantic Scholar
Phase 1 Single and Multiple Ascending Dose Study of CAT-2003, a Novel Activator of Lipoprotein Lipase, Decreases Postprandial Triglycerides†
J. Donovan, Richard L. Dunbar, L. Biernat, Douglas K. Logan +3 more
20143 citations
Semantic Scholar
Abstract: P471 IMPACT OF THE MTP-INHIBITOR AEGR-733 ON THE SINGLE-DOSE PHARMACOKINETICS OF EXTENDED-RELEASE NIACIN
Richard L. Dunbar, L. Bloedon, Ramprasad Gadi, R. Movva +5 more
20093 citations
Semantic Scholar
Impact of the MTP Inhibitor AEGR-733 on Pharmacokinetics of Statins
Danielle Duffy, L. Bloedon, Richard L. Dunbar, Ramprasad Gadi +4 more
20073 citations
Semantic Scholar
Measurement of Atherogenic Lipoproteins in Cardiovascular Risk Assessment
Richard L. Dunbar, D. Rader
20063 citations
Semantic Scholar
Abstract 19133: Inhibition of ANGPTL3 by Evinacumab Reduced Triglycerides (TGs) and LDL-C in Subjects Presenting With Modest Elevations in TGs and/or LDL-C, Recapitulating the Hypolipidemic Effects of Loss-of-Function (LoF) Mutations of ANGPTL3
Richard L. Dunbar, Aurelie Bouzelmat, D. Gipe, R. Pordy +3 more
20162 citations
Semantic Scholar

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