J. Higgs

Most-cited papers

1. Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects

   J. Higgs, C. Wasowski, Alejandra Marcos, M. Jukič +5 more

   2019Heliyon61 citations Open access

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2. In vitro binding affinities of a series of flavonoids for μ-opioid receptors. Antinociceptive effect of the synthetic flavonoid 3,3-dibromoflavanone in mice.

   J. Higgs, C. Wasowski, Leonardo M. Loscalzo, M. Marder

   2013Neuropharmacology45 citations Open access

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3. Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

   D. Knez, N. Colettis, L. Iacovino, M. Sova +13 more

   2020Journal of Medicinal Chemistry44 citations Open access

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4. Novel sulfamides and sulfamates derived from amino esters: Synthetic studies and anticonvulsant activity.

   María L. Villalba, Andrea V. Enrique, J. Higgs, Rocío A Castaño +6 more

   2016European Journal of Pharmacology23 citations Open access

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5. Chronic Intraperitoneal and Oral Treatments with Hesperidin Induce Central Nervous System Effects in Mice

   C. Wasowski, Leonardo M. Loscalzo, J. Higgs, M. Marder

   2012Phytotherapy Research19 citations Open access

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6. Multitarget 2'-hydroxychalcones as potential drugs for the treatment of neurodegenerative disorders and their comorbidities.

   F. Kamecki, D. Knez, Diego Carvalho, Carolina Marcucci +9 more

   2021Neuropharmacology9 citations Open access

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7. N‐propyl‐2,2‐diphenyl‐2‐hydroxyacetamide, a novel &agr;‐hydroxyamide with anticonvulsant, anxiolytic and antidepressant‐like effects that inhibits voltage‐gated sodium channels

   Valentina Pastore, C. Wasowski, P. Martín, Andrea V. Enrique +4 more

   2018European Journal of Pharmacology8 citations Open access

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8. A synthetic bioisoster of trimethadione and phenytoin elicits anticonvulsant effect, protects the brain oxidative damage produced by seizures and exerts antidepressant action in mice.

   Valentina Pastore, C. Wasowski, J. Higgs, I. Mangialavori +2 more

   2014European Neuropsychopharmacology8 citations Open access

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9. "3,3-Dibromoflavanone, a Synthetic Flavonoid Derivative for Pain Management with Antidepressant-Like Effects and Fewer Side Effects than those of Morphine in Mice".

   N. Colettis, J. Higgs, C. Wasowski, D. Knez +3 more

   2024Chemico-Biological Interactions3 citations

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10. Crystal structure of human monoamine oxidase B in complex with styrylpiperidine analogue 84

    L. Iacovino, D. Knez, N. Colettis, M. Sova +11 more

    20203 citations

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11. Crystal structure of human monoamine oxidase B in complex with styrylpiperidine analogue 97

    L. Iacovino, D. Knez, Natalia Colettis, M. Sova +11 more

    20200 citations

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12. In vitro binding af fi nities of a series of fl avonoids for m -opioid receptors. Antinociceptive effect of the synthetic fl avonoid 3,3-dibromo fl avanone in mice

    J. Higgs, C. Wasowski, Leonardo M. Loscalzo, M. Marder

    0 citations

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