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S. Kuttikrishnan · SciRah

Researcher profile · Semantic Scholar

S. Kuttikrishnan

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S. Kuttikrishnan — researcher profile on SciRah

h-index: 23
Works: 63
Citations: 1,833

Most-cited papers

Vascular Endothelial Growth Factor (VEGF) Signaling in Tumour Vascularization: Potential and Challenges.
K. Siveen, K. Prabhu, Roopesh Krishnankutty, S. Kuttikrishnan +5 more
2017Current Vascular Pharmacology190 citations
Semantic Scholar
H2AX: A key player in DNA damage response and a promising target for cancer therapy.
K. Prabhu, S. Kuttikrishnan, Nuha Ahamad, Ummu Habeeba +4 more
2024Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie163 citations Open access
Semantic Scholar
RAS-mediated oncogenic signaling pathways in human malignancies.
A. Q. Khan, S. Kuttikrishnan, K. Siveen, K. Prabhu +5 more
2019Seminars in Cancer Biology161 citations
Semantic Scholar
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
A. Bhat, Salma N. Younes, S. S. Raza, Lubna Zarif +17 more
2020Molecular Cancer127 citations Open access
Semantic Scholar
Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products
K. Siveen, K. Prabhu, Iman W. Achkar, S. Kuttikrishnan +5 more
2018Molecular Cancer115 citations Open access
Semantic Scholar
Dysregulated FOXM1 Signaling in the regulation of cancer stem cells.
Gulab Sher, Tariq Ahmad Masoodi, Kalyani Patil, Sabah Akhtar +3 more
2022Seminars in Cancer Biology98 citations Open access
Semantic Scholar
Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
S. Kuttikrishnan, K. Siveen, K. Prabhu, A. Q. Khan +7 more
2019Frontiers in Oncology83 citations Open access
Semantic Scholar
Natural products as chemo-radiation therapy sensitizers in cancers.
Sabah Nisar, Tariq Ahmad Masoodi, K. Prabhu, S. Kuttikrishnan +8 more
2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie82 citations Open access
Semantic Scholar
Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways.
Kalyani Patil, S. Kuttikrishnan, A. Q. Khan, F. Ahmad +5 more
2021Seminars in Cancer Biology63 citations Open access
Semantic Scholar
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway.
K. Prabhu, A. Bhat, K. Siveen, S. Kuttikrishnan +10 more
2021Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie57 citations Open access
Semantic Scholar
The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer
K. Siveen, A. Raza, Eiman I. Ahmed, A. Q. Khan +9 more
2019Cancers48 citations Open access
Semantic Scholar
Beyond genetics: Exploring the role of epigenetic alterations in breast cancer.
K. Prabhu, Hana Q. Sadida, S. Kuttikrishnan, Kulsoom Junejo +2 more
2024Pathology, Research and Practice45 citations Open access
Semantic Scholar
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
Sabah Akhtar, Iman W. Achkar, K. Siveen, S. Kuttikrishnan +14 more
2019Frontiers in Oncology41 citations Open access
Semantic Scholar
Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells
K. Prabhu, K. Siveen, S. Kuttikrishnan, A. Iskandarani +10 more
2017PLoS ONE41 citations Open access
Semantic Scholar
Bortezomib-mediated downregulation of S-phase kinase protein-2 (SKP2) causes apoptotic cell death in chronic myelogenous leukemia cells
A. Iskandarani, A. Bhat, K. Siveen, K. Prabhu +7 more
2016Journal of Translational Medicine41 citations Open access
Semantic Scholar
Non-Coding RNAs as Regulators and Markers for Targeting of Breast Cancer and Cancer Stem Cells
K. Prabhu, A. Raza, Thasni Karedath, S. S. Raza +9 more
2020Cancers39 citations Open access
Semantic Scholar
Potential therapeutic targets of Guggulsterone in cancer
A. Bhat, K. Prabhu, S. Kuttikrishnan, Roopesh Krishnankutty +3 more
2017Nutrition and Metabolism34 citations Open access
Semantic Scholar
Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia
S. Kuttikrishnan, K. Siveen, K. Prabhu, A. Q. Khan +8 more
2018Leukemia and Lymphoma31 citations
Semantic Scholar
Natural resorcylic acid lactones: a chemical biology approach for anticancer activity.
S. Kuttikrishnan, K. Prabhu, A. A. Al Sharie, Y. A. Al Zu'bi +5 more
2021Drug Discovery Today29 citations Open access
Semantic Scholar
Embelin: a benzoquinone possesses therapeutic potential for the treatment of human cancer.
K. Prabhu, Iman W. Achkar, S. Kuttikrishnan, Sabah Akhtar +3 more
2018Future Medicinal Chemistry28 citations
Semantic Scholar
Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines
K. Prabhu, K. Siveen, S. Kuttikrishnan, A. Iskandarani +8 more
2018Frontiers in Pharmacology28 citations Open access
Semantic Scholar
Curcumin-Mediated Degradation of S-Phase Kinase Protein 2 Induces Cytotoxic Effects in Human Papillomavirus-Positive and Negative Squamous Carcinoma Cells
A. Q. Khan, K. Siveen, K. Prabhu, S. Kuttikrishnan +6 more
2018Frontiers in Oncology27 citations Open access
Semantic Scholar
Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species
A. Q. Khan, E. A. Mohamed, Ishrat Hakeem, A. Nazeer +7 more
2020Molecules24 citations Open access
Semantic Scholar
Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
K. Prabhu, K. Siveen, S. Kuttikrishnan, A. Jochebeth +11 more
2019Biomolecules20 citations Open access
Semantic Scholar
PI3 K/AKT/mTOR pathway and its role in breast cancer stem cells
K. Prabhu, S. Kuttikrishnan, Zahwa Mariyam, Ummu Habeeba +4 more
2025Naunyn-Schmiedeberg's Archives of Pharmacology19 citations Open access
Semantic Scholar
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
K. Prabhu, Fareed Ahmad, S. Kuttikrishnan, Rari Leo +11 more
2024Cell Death Discovery19 citations Open access
Semantic Scholar
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer
Abbas Khan, Y. Waheed, S. Kuttikrishnan, K. Prabhu +4 more
2024Frontiers in Pharmacology17 citations Open access
Semantic Scholar
Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells
S. Kuttikrishnan, K. Prabhu, A. Q. Khan, F. Alali +2 more
2021Leukemia and Lymphoma16 citations
Semantic Scholar
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells.
S. Kuttikrishnan, A. Bhat, J. Mateo, F. Ahmad +5 more
2022Biochemical and Biophysical Research Communications - BBRC13 citations Open access
Semantic Scholar
The cross-talk between miRNAs and JAK/STAT pathway in cutaneous T cell lymphoma: Emphasis on therapeutic opportunities.
Kalyani Patil, Gulab Sher, S. Kuttikrishnan, Safwan Moton +5 more
2022Seminars in Cell and Developmental Biology13 citations Open access
Semantic Scholar
Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway
Sabah Akhtar, Lubna Zarif, S. Kuttikrishnan, K. Prabhu +7 more
2022Cancers12 citations Open access
Semantic Scholar
Sanguinarine Triggers Apoptosis in Cutaneous Squamous Cell Carcinoma Cells through Reactive Oxygen Species-Dependent c-Jun N-Terminal Kinase Signaling Pathway.
Kalyani Patil, Abdul Q. Khan, Fareed Ahmad, S. Kuttikrishnan +7 more
2024Frontiers in Bioscience11 citations Open access
Semantic Scholar
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
S. Kuttikrishnan, Fareed Ahmad, J. Mateo, K. Prabhu +7 more
2023Cell Biology International10 citations Open access
Semantic Scholar
Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis
S. Kuttikrishnan, Tariq Ahmad Masoodi, Gulab Sher, Ajaz A. Bhat +8 more
2022Frontiers in Oncology10 citations Open access
Semantic Scholar
The apoptotic and anti‐proliferative effects of Neosetophomone B in T‐cell acute lymphoblastic leukaemia via PI3K/AKT/mTOR pathway inhibition
S. Kuttikrishnan, A. W. Ansari, M. Suleman, Fareed Ahmad +9 more
2024Cell Proliferation9 citations Open access
Semantic Scholar
Signaling networks guiding erythropoiesis
S. Kuttikrishnan, K. Prabhu, Abdul Q. Khan, Shahab Uddin
2024Current opinion in hematology8 citations
Semantic Scholar
Anticancer Potential and Molecular Targets of Pristimerin in Human Malignancies
K. Prabhu, Serah Jessy, S. Kuttikrishnan, Farina Mujeeb +5 more
2024Pharmaceuticals8 citations Open access
Semantic Scholar
Role of animal research in human malignancies
A. Q. Khan, K. Siveen, K. Prabhu, S. Kuttikrishnan +5 more
2019Animal Models in Cancer Drug Discovery8 citations
Semantic Scholar
Beyond Viral Infections: The Multifaceted Roles of Human Papillomavirus and Epstein-Barr Virus in Shaping the Tumor Microenvironment.
Queenie Fernandes, Gulab Sher, K. Prabhu, S. Kuttikrishnan +5 more
2024Discover medicine7 citations Open access
Semantic Scholar
Analysis of signaling cascades from myeloma cells treated with pristimerin.
Heba Almaghrbi, Rehab Elkardawy, S. Kumar, S. Kuttikrishnan +6 more
2023Advances in Protein Chemistry and Structural Biology6 citations
Semantic Scholar
Oncogenic role of dysregulated leptin signaling in the pathogenesis of ovarian cancer
Iman W. Achkar, A. Bhat, M. Zafar, Madiha Abbas +4 more
2019Translational Medicine Communications6 citations Open access
Semantic Scholar
Fatty acid synthase: A key driver of ovarian cancer metastasis and a promising therapeutic target.
Nuha Ahmad, Safwan Moton, S. Kuttikrishnan, K. Prabhu +3 more
2024Pathology, Research and Practice5 citations Open access
Semantic Scholar
Nectin-4: A promising prognostic marker and therapeutic target in cancer.
S. Kuttikrishnan, K. Prabhu, Ummu Habeeba, Zahwa Mariyam +5 more
2025International Review of Cell and Molecular Biology4 citations
Semantic Scholar
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway.
S. Kuttikrishnan, Tariq Ahmad Masoodi, Fareed Ahmad, Gulab Sher +10 more
2023Journal of dermatological science (Amsterdam)4 citations
Semantic Scholar
Correction to: Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
A. Bhat, Salma N. Younes, S. S. Raza, Lubna Zarif +17 more
2020Molecular Cancer4 citations Open access
Semantic Scholar
Selective Induction of Apoptosis in T-cell Acute Lymphoblastic Leukemia by Pristimerin Through Dual PI3K/AKT Pathway Inhibition and ROS Generation.
S. Kuttikrishnan, Zahwa Mariyam, Fareed Ahmad, M. Suleman +9 more
2025European Journal of Pharmacology3 citations Open access
Semantic Scholar
Targeting mTOR and Its Associated Signaling to Induce Cell Death in Breast Cancer Stem Cells
K. Prabhu, Zahwa Mariyam, S. A. Rahman, S. Kuttikrishnan +8 more
2025Cell Biology International3 citations
Semantic Scholar
Association between metabolic risk, oxidative stress and psychological parameters amongst sample of nurses working in Doha, Qatar
K. Prabhu, Ummu Habeeba, Mohammad Usman Asad Rahman, María S. Pérez +9 more
2025Clinical Epidemiology and Global Health2 citations Open access
Semantic Scholar
Curcumin induces apoptosis via downregulation of SKP2 and induction of GADD45A/CDKN1A expression through generation of ROS in cutaneous T-cell lymphoma cells.
S. Kuttikrishnan, M. Suleman, Fareed Ahmad, Zahwa Mariyam +5 more
2025Toxicology and Applied Pharmacology2 citations Open access
Semantic Scholar
Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model.
S. Kuttikrishnan, Maram Hasan, K. Prabhu, T. El-Elimat +8 more
2024Experimental Cell Research2 citations
Semantic Scholar

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