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K. Frayn · SciRah

Researcher profile · Semantic Scholar

K. Frayn

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K. Frayn — researcher profile on SciRah

h-index: 74
Works: 290
Citations: 21K

Most-cited papers

Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation
F. Karpe, J. Dickmann, K. Frayn
2011Diabetes884 citations Open access
Semantic Scholar
Gluteofemoral body fat as a determinant of metabolic health
K. Manolopoulos, F. Karpe, K. Frayn
2010International Journal of Obesity786 citations Open access
Semantic Scholar
Dynamics of human adipose lipid turnover in health and metabolic disease
P. Arner, Samuel Bernard, M. Salehpour, G. Possnert +10 more
2011Nature383 citations Open access
Semantic Scholar
Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages
V. Bourlier, A. Zakaroff-Girard, A. Miranville, S. D. de Barros +7 more
2008Circulation379 citations
Semantic Scholar
Physical activity and exercise in the regulation of human adipose tissue physiology.
Dylan Thompson, F. Karpe, M. Lafontan, K. Frayn
2012Physiological Reviews372 citations
Semantic Scholar
Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men
U. Risérus, D. Sprecher, Tony G. Johnson, E. Olson +20 more
2008Diabetes334 citations
Semantic Scholar
Fatty acid metabolism in adipose tissue, muscle and liver in health and disease.
K. Frayn, P. Arner, H. Yki-Järvinen
2006Essays in Biochemistry304 citations
Semantic Scholar
Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period
A. Bickerton, R. Roberts, B. Fielding, L. Hodson +5 more
2007Diabetes249 citations Open access
Semantic Scholar
Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding.
M. Chong, L. Hodson, A. Bickerton, R. Roberts +4 more
2008American Journal of Clinical Nutrition229 citations Open access
Semantic Scholar
GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: implications for understanding genetic association signals at this locus.
L. McCulloch, M. van de Bunt, M. Braun, K. Frayn +2 more
2011Molecular Genetics and Metabolism223 citations
Semantic Scholar
Leukocyte Activation by Triglyceride-Rich Lipoproteins
A. Alipour, A. J. van Oostrom, Alisa Izraeljan, C. Verseyden +5 more
2008Arteriosclerosis, Thrombosis and Vascular Biology217 citations Open access
Semantic Scholar
Adipose Dipeptidyl Peptidase-4 and Obesity
H. Sell, M. Blüher, N. Klöting, R. Schlich +8 more
2013Diabetes Care183 citations Open access
Semantic Scholar
Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications
Katherine E. Pinnick, G. Nicholson, K. Manolopoulos, S. Mcquaid +9 more
2014Diabetes174 citations
Semantic Scholar
Regulation of human metabolism by hypoxia-inducible factor
F. Formenti, D. Constantin-Teodosiu, Yaso Emmanuel, J. Cheeseman +18 more
2010Proceedings of the National Academy of Sciences of the United States of America169 citations Open access
Semantic Scholar
Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity
Adeline Bertola, V. Deveaux, S. Bonnafous, D. Rousseau +13 more
2009Diabetes154 citations Open access
Semantic Scholar
Fat as a fuel: emerging understanding of the adipose tissue–skeletal muscle axis
K. Frayn
2010Acta Physiologica129 citations
Semantic Scholar
De Novo Lipogenesis and Stearoyl-CoA Desaturase Are Coordinately Regulated in the Human Adipocyte and Protect against Palmitate-induced Cell Injury*
Jennifer M. Collins, M. Neville, Michael B. Hoppa, K. Frayn
2009Journal of Biological Chemistry113 citations Open access
Semantic Scholar
De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation[S]
Jennifer M. Collins, M. Neville, Katherine E. Pinnick, L. Hodson +5 more
2011Journal of Lipid Research110 citations Open access
Semantic Scholar
Obesity and metabolic disease: is adipose tissue the culprit?
K. Frayn
2005Proceedings of the Nutrition Society110 citations Open access
Semantic Scholar
Gluteofemoral Adipose Tissue Plays a Major Role in Production of the Lipokine Palmitoleate in Humans
Katherine E. Pinnick, M. Neville, B. Fielding, K. Frayn +2 more
2012Diabetes100 citations Open access
Semantic Scholar
The Contribution of Splanchnic Fat to VLDL Triglyceride Is Greater in Insulin-Resistant Than Insulin-Sensitive Men and Women
L. Hodson, A. Bickerton, S. Mcquaid, R. Roberts +3 more
2007Diabetes99 citations
Semantic Scholar
Reduced oxidation of dietary fat after a short term high-carbohydrate diet.
R. Roberts, A. Bickerton, B. Fielding, E. Blaak +5 more
2008American Journal of Clinical Nutrition87 citations Open access
Semantic Scholar
Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis
V. van Harmelen, Anna S. Eriksson, G. Åström, K. Wåhlén +7 more
2008Diabetes85 citations
Semantic Scholar
Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease.
J. Westerbacka, A. Kotronen, B. Fielding, J. Wahren +11 more
2010Gastroenterology82 citations Open access
Semantic Scholar
Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men
J. Jocken, G. Goossens, A. M. V. van Hees, K. Frayn +5 more
2007Diabetologia82 citations Open access
Semantic Scholar
Sex differences in lipid and glucose kinetics after ingestion of an acute oral fructose load
C. Tran, Delphine Jacot-Descombes, V. Lecoultre, B. Fielding +6 more
2010British Journal of Nutrition81 citations Open access
Semantic Scholar
Metabolic interaction of dietary sugars and plasma lipids with a focus on mechanisms and de novo lipogenesis
M. Chong, B. Fielding, K. Frayn
2007Proceedings of the Nutrition Society79 citations Open access
Semantic Scholar
Femoral Adipose Tissue May Accumulate the Fat That Has Been Recycled as VLDL and Nonesterified Fatty Acids
S. Mcquaid, S. Humphreys, L. Hodson, B. Fielding +2 more
2010Diabetes76 citations Open access
Semantic Scholar
Hepatic fatty acid partitioning
L. Hodson, K. Frayn
2011Current Opinion in Lipidology70 citations
Semantic Scholar
Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes
T. Cadoudal, J. Blouin, M. Collinet, Françoise Fouque +8 more
2007Diabetologia67 citations Open access
Semantic Scholar
Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men
K. Marinou, M. Adiels, L. Hodson, K. Frayn +2 more
2011British Journal of Nutrition66 citations Open access
Semantic Scholar
Substrate Utilization by the Failing Human Heart by Direct Quantification Using Arterio-Venous Blood Sampling
J. Funada, T. Betts, L. Hodson, S. Humphreys +3 more
2009PLoS ONE63 citations Open access
Semantic Scholar
Dietary Approaches to Stop Hypertension (DASH) diet: applicability and acceptability to a UK population.
K. Harnden, K. Frayn, L. Hodson
2010Journal of human nutrition and dietetics (Print)62 citations
Semantic Scholar
Cardiovascular disease : diet, nutrition and emerging risk factors : the report of a British Nutrition Foundation task force
K. Frayn, S. Stanner
200557 citations
Semantic Scholar
Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state.
R. B. Heath, F. Karpe, R. Milne, G. Burdge +2 more
2007American Journal of Physiology. Endocrinology and Metabolism55 citations
Semantic Scholar
Mapping of the fibroblast growth factors in human white adipose tissue.
N. Mejhert, J. Galitzky, Amanda T. Pettersson, C. Bambace +6 more
2010Journal of Clinical Endocrinology and Metabolism53 citations Open access
Semantic Scholar
Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased
K. Frayn, D. Langin, F. Karpe
2008Diabetologia52 citations Open access
Semantic Scholar
Metabolic characteristics of human subcutaneous abdominal adipose tissue after overnight fast.
K. Frayn, S. Humphreys
2012American Journal of Physiology. Endocrinology and Metabolism51 citations Open access
Semantic Scholar
Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo
K. Manolopoulos, F. Karpe, K. Frayn
2012Diabetologia43 citations Open access
Semantic Scholar
Adipose Tissue: A Key Target for Diabetes Pathophysiology and Treatment?
K. Frayn, G. Tan, F. Karpe
2007Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme43 citations
Semantic Scholar
Adipocyte Triglyceride Turnover Is Independently Associated With Atherogenic Dyslipidemia
K. Frayn, Samuel Bernard, Kirsty L. Spalding, P. Arner
2012Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease36 citations Open access
Semantic Scholar
Fatty acid metabolism in patients with PPARgamma mutations.
G. Tan, D. Savage, B. Fielding, Jennifer M. Collins +6 more
2008Journal of Clinical Endocrinology and Metabolism30 citations
Semantic Scholar
Addition of n-3 fatty acids to a 4-hour lipid infusion does not affect insulin sensitivity, insulin secretion, or markers of oxidative stress in subjects with type 2 diabetes mellitus.
I. L. Mostad, K. Bjerve, S. Basu, P. Sutton +2 more
2009Metabolism: Clinical and Experimental28 citations
Semantic Scholar
Oscillations of fatty acid and glycerol release from human subcutaneous adipose tissue in vivo.
F. Karpe, B. Fielding, S. Coppack, V. J. Lawrence +2 more
2005Diabetes26 citations
Semantic Scholar
Disturbed cholesterol homeostasis in hormone-sensitive lipase-null mice.
C. Fernandez, M. Lindholm, Morten Krogh, S. Lucas +7 more
2008American Journal of Physiology. Endocrinology and Metabolism24 citations Open access
Semantic Scholar
Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo
Lisa M. Tussing-Humphreys, K. Frayn, Steven R. Smith, M. Westerman +4 more
2011TheScientificWorldJournal22 citations Open access
Semantic Scholar
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia.
K. Evans, G. Burdge, S. Wootton, Jennifer M. Collins +4 more
2008Atherosclerosis22 citations
Semantic Scholar
Effects of short-term low- and high-carbohydrate diets on postprandial metabolism in non-diabetic and diabetic subjects.
K. S. Culling, H. Neil, M. Gilbert, K. Frayn
2009NMCD. Nutrition Metabolism and Cardiovascular Diseases21 citations
Semantic Scholar
Altered Desaturation and Elongation of Fatty Acids in Hormone-Sensitive Lipase Null Mice
C. Fernandez, Kai Schuhmann, R. Herzog, B. Fielding +5 more
2011PLoS ONE20 citations Open access
Semantic Scholar
Comprar Metabolic Regulation: A Human Perspective, 3rd Edition | Keith Frayn | 9781405183598 | Blackwell Publishing
K. Frayn
201020 citations
Semantic Scholar

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F. Karpe×20
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F. Karpe — researcher profile on SciRah
B. Fielding×16
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L. Hodson×11
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P. Arner×6
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S. Humphreys — researcher profile on SciRah

Jennifer M. Collins×5

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Jennifer M. Collins — researcher profile on SciRah

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A. Bickerton×4

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A. Bickerton — researcher profile on SciRah

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R. Roberts — researcher profile on SciRah

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M. Neville — researcher profile on SciRah

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S. Mcquaid — researcher profile on SciRah

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G. Tan — researcher profile on SciRah