Researcher profile · Semantic Scholar

H. Lim

h-index: 19
Works: 33
Citations: 1,197

Most-cited papers

Exit from mitosis in budding yeast: biphasic inactivation of the Cdc28-Clb2 mitotic kinase and the role of Cdc20.
F. M. Yeong, H. Lim, C. G. Padmashree, U. Surana
2000Molecules and Cells184 citations Open access
Semantic Scholar
Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast.
H. Lim, P. Goh, U. Surana
1998Current Biology172 citations Open access
Semantic Scholar
Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28
H. Lim, P. Goh, U. Surana
1996Molecular and Cellular Biology110 citations Open access
Semantic Scholar
Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle
K. Crasta, H. Lim, T. Giddings, M. Winey +1 more
2008Nature Cell Biology76 citations Open access
Semantic Scholar
Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo
Chen Chen, H. Lim, Jian Shi, Sachiko Tamura +3 more
2016bioRxiv64 citations Open access
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Early Expressed Clb Proteins Allow Accumulation of Mitotic Cyclin by Inactivating Proteolytic Machinery during S Phase
F. M. Yeong, H. Lim, Ya Wang, U. Surana
2001Molecular and Cellular Biology58 citations Open access
Semantic Scholar
Regulation of centrosome separation in yeast and vertebrates: common threads.
H. Lim, Zhang Tao, U. Surana
2009Trends in Cell Biology52 citations
Semantic Scholar
DNA damage checkpoint maintains CDH1 in an active state to inhibit anaphase progression.
Zhang Tao, Saurabh R. Nirantar, H. Lim, Indrajit Sinha +1 more
2009Developmental Cell49 citations Open access
Semantic Scholar
Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells.
Hao-Jie Yu, H. Lim, N. Tjokro, P. Sathiyanathan +6 more
2014Cell Reports42 citations Open access
Semantic Scholar
TPPP acts downstream of RhoA–ROCK–LIMK2 to regulate astral microtubule organization and spindle orientation
Yi-Wen Heng, H. Lim, T. Mina, Prayudi Utomo +3 more
2012Journal of Cell Science42 citations Open access
Semantic Scholar
DNA damage checkpoint execution and the rules of its disengagement
C. Yam, H. Lim, U. Surana
2022Frontiers in Cell and Developmental Biology38 citations Open access
Semantic Scholar
Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis
Weimei Ruan, H. Lim, U. Surana
2019Front. Cell Dev. Biol.37 citations Open access
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Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket
S. Kannan, G. Venkatachalam, H. Lim, U. Surana +1 more
2018Chemical Science36 citations Open access
Semantic Scholar
Dephosphorylation of threonine 169 of Cdc28 is not required for exit from mitosis but may be necessary for start in Saccharomyces cerevisiae
H. Lim, C. Loy, Sara Zaman, Uttam Surana
1996Molecular and Cellular Biology34 citations Open access
Semantic Scholar
MEN, destruction and separation: mechanistic links between mitotic exit and cytokinesis in budding yeast.
U. Surana, F. M. Yeong, H. Lim
2002Bioessays32 citations
Semantic Scholar
Electron cryotomography analysis of Dam1C/DASH at the kinetochore–spindle interface in situ
Cai-Tong Ng, Li Deng, Chen Chen, H. Lim +3 more
2018Journal of Cell Biology28 citations Open access
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Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysisis not acutely dependent on the activity of anaphase-promoting complex.
P. Goh, H. Lim, Uttam Surana
2000European Journal of Biochemistry25 citations
Semantic Scholar
Cdk1 promotes kinetochore bi‐orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest
Hongqing Liang, H. Lim, A. Venkitaraman, U. Surana
2011EMBO Journal22 citations Open access
Semantic Scholar
Tome-1, wee1, and the onset of mitosis: coupled destruction for timely entry.
H. Lim, U. Surana
2003Molecules and Cells21 citations Open access
Semantic Scholar
Deficiency of centromere-associated protein Slk19 causes premature nuclear migration and loss of centromeric elasticity
Zhang Tao, H. Lim, Chee-Seng Cheng, U. Surana
2006Journal of Cell Science17 citations Open access
Semantic Scholar
Emerging Roles of Downstream of Kinase 3 in Cell Signaling
J. Loh, J. Teo, H. Lim, Kong-Peng Lam
2020Frontiers in Immunology15 citations Open access
Semantic Scholar
Bruton’s tyrosine kinase phosphorylates scaffolding and RNA-binding protein G3BP1 to induce stress granule aggregation during host sensing of foreign ribonucleic acids
Susana Soo-Yeon Kim, D. Sim, G. Carissimo, H. Lim +1 more
2022Journal of Biological Chemistry10 citations Open access
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Dun1, a Chk2-related kinase, is the central regulator of securin-separase dynamics during DNA damage signaling
C. Yam, David Boy Chia, Idina Y Shi, H. Lim +1 more
2020Nucleic Acids Research9 citations Open access
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A Novel Cell Cycle Inhibitor Stalls Replication Forks and Activates S Phase Checkpoint
V. Krishnan, L. Dirick, H. Lim, Tiffany Siew Joo Lim +6 more
2007Cell Cycle8 citations Open access
Semantic Scholar
Disrupting the Dok3–Card9 Interaction with Synthetic Peptides Enhances Antifungal Effector Functions of Human Neutrophils
J. Loh, J. Teo, S. Kannan, C. Verma +2 more
2023Pharmaceutics5 citations Open access
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Identification of a novel mitochondria-localized LKB1 variant required for the regulation of the oxidative stress response
I. Tan, Shengli Xu, J. Huo, Yuhan Huang +2 more
2023Journal of Biological Chemistry5 citations Open access
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Chaperoning HMGA 2 Protein Protects Stalled Replication Forks in Stem and Cancer Cells
Hao-Jie Yu, H. Lim, N. Tjokro, P. Sathiyanathan +6 more
20195 citations
Semantic Scholar
A multi-scale model of the yeast chromosome-segregation system
Cai-Tong Ng, Li Deng, Chen Chen, H. Lim +3 more
2018bioRxiv1 citations Open access
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Staging a recovery from mitotic arrest
U. Surana, Hongqing Liang, H. Lim
2012BioArchitecture1 citations Open access
Semantic Scholar
Cdk 1 promotes kinetochore bi-orientation and regulates Cdc 20 expression during recovery spindle checkpoint arrest
Hongqing Liang, H. Lim, A. Venkitaraman, U. Surana
20111 citations
Semantic Scholar
Metabolic engineering approach to boost γ-decalactone production in S. cerevisiae identifies a critical role for the peroxisomal Fatty Acyl-CoA Synthetase Faa2
David Boy Chia, J. Chow, Mohammad Alfatah, Shawn Hoon +3 more
2025bioRxiv0 citations Open access
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cerevisiae.for start in Saccharomyces not required for exit from mitosis but may be Dephosphorylation of threonine 169 of Cdc28 is
H. Lim, C. Loy, S. Zaman, U. Surana
20130 citations
Semantic Scholar
The "suppressive side" of yeast mitotic cyclins
U. Surana, H. Lim
2011Cell Cycle0 citations Open access
Semantic Scholar

Chen Chen

×3

Jian Shi×3

L. Gan×3

Zhang Tao×3

Hongqing Liang×3

Hao-Jie Yu×2

N. Tjokro×2

P. Sathiyanathan×2