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R. Coppini · SciRah

Researcher profile · Semantic Scholar

R. Coppini

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R. Coppini — researcher profile on SciRah

h-index: 39
Works: 184
Citations: 4,232

Most-cited papers

Amelioration of diastolic dysfunction by dapagliflozin in a non-diabetic model involves coronary endothelium.
D. Cappetta, A. De Angelis, L. Ciuffreda, R. Coppini +16 more
2020Pharmacological Research110 citations
Semantic Scholar
Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy: The RESTYLE-HCM Randomized, Double-Blind, Placebo-Controlled Study
I. Olivotto, P. Camici, P. Merlini, C. Rapezzi +19 more
2018Circulation: Heart Failure110 citations Open access
Semantic Scholar
Defining the diagnostic effectiveness of genes for inclusion in panels: the experience of two decades of genetic testing for hypertrophic cardiomyopathy at a single center
F. Mazzarotto, F. Girolami, B. Boschi, F. Barlocco +14 more
2018Genetics in Medicine80 citations Open access
Semantic Scholar
Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy
R. Coppini, C. Ferrantini, J. Pioner, L. Santini +15 more
2019JACC: Basic to Translational Science71 citations Open access
Semantic Scholar
Altered Ca2+ and Na+ Homeostasis in Human Hypertrophic Cardiomyopathy: Implications for Arrhythmogenesis
R. Coppini, C. Ferrantini, A. Mugelli, C. Poggesi +1 more
2018Frontiers in Physiology69 citations Open access
Semantic Scholar
Comparison of long‐term outcome in anthracycline‐related versus idiopathic dilated cardiomyopathy: a single centre experience
A. Fornaro, I. Olivotto, L. Rigacci, M. Ciaccheri +9 more
2018European Journal of Heart Failure63 citations Open access
Semantic Scholar
Sex-specific classification of drug-induced Torsade de Pointes susceptibility using cardiac simulations and machine learning
Alex Fogli Iseppe, Hai-Bo Ni, Sicheng Zhu, Xianwei Zhang +7 more
2020bioRxiv61 citations Open access
Semantic Scholar
Abnormalities in Sodium Current and Calcium Homeostasis as Drivers of Arrhythmogenesis in Hypertrophic Cardiomyopathy.
R. Coppini, L. Santini, I. Olivotto, M. Ackerman +1 more
2020Cardiovascular Research57 citations Open access
Semantic Scholar
Late sodium current inhibitors to treat exercise‐induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium
C. Ferrantini, J. Pioner, L. Mazzoni, F. Gentile +11 more
2018British Journal of Pharmacology56 citations Open access
Semantic Scholar
Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain
L. Dini, M. del Lungo, F. Resta, M. Melchiorre +9 more
2018Frontiers in Pharmacology51 citations Open access
Semantic Scholar
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction
C. Ferrantini, J. M. Pioner, D. Martella, R. Coppini +10 more
2019Circulation Research45 citations Open access
Semantic Scholar
Real‐time optical manipulation of cardiac conduction in intact hearts
Marina Scardigli, C. Müllenbroich, E. Margoni, Samantha Cannazzaro +13 more
2018Journal of Physiology45 citations Open access
Semantic Scholar
Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB
C. Miceli, Y. Santin, Nicola Manzella, R. Coppini +5 more
2018Oxidative Medicine and Cellular Longevity45 citations Open access
Semantic Scholar
Pharmacological Management of Hypertrophic Cardiomyopathy: From Bench to Bedside
C. Palandri, L. Santini, A. Argirò, F. Margara +4 more
2022Drugs44 citations Open access
Semantic Scholar
Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates
J. Pioner, L. Santini, C. Palandri, D. Martella +19 more
2019International Journal of Molecular Sciences44 citations Open access
Semantic Scholar
Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development
Vincenzo Lionetti, S. Bollini, R. Coppini, A. Gerbino +18 more
2021Pharmacological Research36 citations Open access
Semantic Scholar
Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle
B. Scellini, N. Piroddi, M. Dente, Giulia Vitale +5 more
2021The Journal of General Physiology36 citations Open access
Semantic Scholar
Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM
J. Pioner, Giulia Vitale, Sonette Steczina, M. Langione +21 more
2023Circulation Research34 citations Open access
Semantic Scholar
Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models.
Matteo Urru, Mirko Muzzi, E. Coppi, G. Ranieri +9 more
2019Pain34 citations
Semantic Scholar
Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms
V. Biasci, L. Santini, G. A. Marchal, S. Hussaini +10 more
2022Basic Research in Cardiology33 citations Open access
Semantic Scholar
Histopathological comparison of intramural coronary artery remodeling and myocardial fibrosis in obstructive versus end-stage hypertrophic cardiomyopathy.
A. Foà, V. Agostini, C. Rapezzi, I. Olivotto +11 more
2019International Journal of Cardiology30 citations Open access
Semantic Scholar
Ion Channel Impairment and Myofilament Ca2+ Sensitization: Two Parallel Mechanisms Underlying Arrhythmogenesis in Hypertrophic Cardiomyopathy
L. Santini, R. Coppini, E. Cerbai
2021Cells29 citations Open access
Semantic Scholar
Pathophysiology and Treatment of Hypertrophic Cardiomyopathy: New Perspectives
M. Zampieri, Martina Berteotti, C. Ferrantini, L. Tassetti +8 more
2021Current Heart Failure Reports28 citations
Semantic Scholar
Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different TNNT2 Mutations
J. Pioner, Giulia Vitale, F. Gentile, B. Scellini +8 more
2022Frontiers in Physiology22 citations Open access
Semantic Scholar
Modelling genetic diseases for drug development: Hypertrophic cardiomyopathy.
L. Santini, C. Palandri, C. Nediani, E. Cerbai +1 more
2020Pharmacological Research21 citations Open access
Semantic Scholar
Real-World Use and Predictors of Response to Disopyramide in Patients with Obstructive Hypertrophic Cardiomyopathy
N. Maurizi, C. Chiriatti, C. Fumagalli, M. Targetti +10 more
2023Journal of Clinical Medicine20 citations Open access
Semantic Scholar
Long-Term Prevalence of Systolic Dysfunction in MYBPC3 Versus MYH7-Related Hypertrophic Cardiomyopathy
M. Beltrami, E. Fedele, C. Fumagalli, F. Mazzarotto +7 more
2023Circulation Genomic and Precision Medicine20 citations Open access
Semantic Scholar
Optical clearing in cardiac imaging: A comparative study.
C. Olianti, F. Giardini, E. Lazzeri, I. Costantini +5 more
2021Progress in Biophysics and Molecular Biology20 citations Open access
Semantic Scholar
A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study
Kathleen C. Woulfe, C. Ferrara, J. Pioner, Jennifer H. Mahaffey +7 more
2019Frontiers in Cardiovascular Medicine19 citations Open access
Semantic Scholar
Pharmacological Inhibition of Serine Proteases to Reduce Cardiac Inflammation and Fibrosis in Atrial Fibrillation
R. Coppini, L. Santini, C. Palandri, L. Sartiani +2 more
2019Frontiers in Pharmacology17 citations Open access
Semantic Scholar
Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency
J. Pioner, L. Santini, C. Palandri, M. Langione +20 more
2022Frontiers in Physiology16 citations Open access
Semantic Scholar
Remodelling of potassium currents underlies arrhythmic action potential prolongation under beta-adrenergic stimulation in hypertrophic cardiomyopathy
R. Doste, R. Coppini, A. Bueno-Orovio
2022bioRxiv16 citations Open access
Semantic Scholar
Anti-hypertensive drugs deprescribing: an updated systematic review of clinical trials
S. Crisafulli, N. Luxi, R. Coppini, A. Capuano +6 more
2021BMC Family Practice16 citations Open access
Semantic Scholar
Safety and efficacy of ranolazine in hypertrophic cardiomyopathy: Real-world experience in a National Referral Center.
A. Argirò, M. Zampieri, L. Dei, C. Ferrantini +13 more
2022International Journal of Cardiology15 citations Open access
Semantic Scholar
Mechanisms of ischaemia-induced arrhythmias in hypertrophic cardiomyopathy: a large-scale computational study
J. Coleman, R. Doste, Z. Ashkir, R. Coppini +4 more
2024Cardiovascular Research14 citations Open access
Semantic Scholar
Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy
J. Coleman, R. Doste, M. Beltrami, A. Argirò +4 more
2024Frontiers in Pharmacology13 citations Open access
Semantic Scholar
T-tubule remodeling in human hypertrophic cardiomyopathy
Giulia Vitale, R. Coppini, C. Tesi, C. Poggesi +2 more
2020Journal of Muscle Research and Cell Motility13 citations Open access
Semantic Scholar
Advances in Stem Cell Modeling of Dystrophin-Associated Disease: Implications for the Wider World of Dilated Cardiomyopathy
J. Pioner, A. Fornaro, R. Coppini, N. Ceschia +6 more
2020Frontiers in Physiology11 citations Open access
Semantic Scholar
Genetic characterization of juvenile sudden cardiac arrest and death in Tuscany: The ToRSADE registry
F. Girolami, V. Spinelli, N. Maurizi, Martina Focardi +10 more
2022Frontiers in Cardiovascular Medicine10 citations Open access
Semantic Scholar
Electrophysiological mechanisms underlying T wave pseudonormalisation on stress ECGs in hypertrophic cardiomyopathy
J. Coleman, R. Doste, M. Beltrami, R. Coppini +3 more
2023Comput. Biol. Medicine9 citations Open access
Semantic Scholar
Arrhythmia susceptibility in a rat model of acute atrial dilation.
M. Scardigli, S. Cannazzaro, R. Coppini, C. Crocini +7 more
2020Progress in Biophysics and Molecular Biology9 citations
Semantic Scholar
Mavacamten depresses human atrial contractility in the same EC50% range as human ventricle
C. Ferrantini, B. Scellini, Giulia Vitale, J. Pioner +5 more
2022Biophysical Journal8 citations Open access
Semantic Scholar
Channelopathies, cardiac hypertrophy, and the theory of light.
I. Olivotto, R. Coppini
2018European Heart Journal8 citations Open access
Semantic Scholar
NaV1.8: a novel contributor to cardiac arrhythmogenesis in heart failure.
R. Coppini, C. Ferrantini
2018Cardiovascular Research7 citations Open access
Semantic Scholar
Clinical and Molecular Aspects of Cardiomyopathies: Emerging Therapies and Clinical Trials.
N. Maurizi, E. Ammirati, R. Coppini, A. Morrone +1 more
2018Heart Failure Clinics7 citations
Semantic Scholar
Cardiomyocyte-specific Gq signalling and arrhythmias: novel insights from DREADD technology.
Cecilia Ferrantini, R. Coppini, L. Sacconi
2019Cardiovascular Research6 citations Open access
Semantic Scholar
Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes
M. Scardigli, Michal Pásek, L. Santini, C. Palandri +13 more
2023bioRxiv5 citations Open access
Semantic Scholar
Cell spheroid micromechanics under large deformations
Dimosthenis Giannopoulos, Maja Schlittler, M. De Bortoli, R. Coppini +6 more
2025Scientific Reports4 citations Open access
Semantic Scholar
Cancer Treatment-Related Complications in Patients With Hypertrophic Cardiomyopathy.
M. Zampieri, S. Schoonvelde, Michele Vinci, I. Meattini +11 more
2024Mayo Clinic proceedings4 citations
Semantic Scholar
Cardiac safety assessment of a novel recombinant bispecific antibody targeting the ether-à-go-go related gene 1 (hERG1)-β1 integrin macromolecular complex
L. Santini, Claudia Duranti, C. Palandri, L. Giammarino +8 more
2023Frontiers in Pharmacology3 citations Open access
Semantic Scholar

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