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N. Adachi · SciRah

Researcher profile · Semantic Scholar

N. Adachi

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N. Adachi — researcher profile on SciRah

h-index: 19
Works: 57
Citations: 1,101

Most-cited papers

Enzymological Analysis of Mutant Protein Kinase Cγ Causing Spinocerebellar Ataxia Type 14 and Dysfunction in Ca2+ Homeostasis*
N. Adachi, Takeshi Kobayashi, Hideyuki Takahashi, Takumi Kawasaki +6 more
2008Journal of Biological Chemistry105 citations Open access
Semantic Scholar
Mutant Protein Kinase Cγ Found in Spinocerebellar Ataxia Type 14 Is Susceptible to Aggregation and Causes Cell Death*
T. Seki, N. Adachi, Y. Ono, H. Mochizuki +7 more
2005Journal of Biological Chemistry70 citations Open access
Semantic Scholar
Mutant gammaPKC found in spinocerebellar ataxia type 14 induces aggregate-independent maldevelopment of dendrites in primary cultured Purkinje cells.
T. Seki, Takayuki Shimahara, Kazuhiro Yamamoto, Nana Abe +6 more
2009Neurobiology of Disease65 citations Open access
Semantic Scholar
S-Palmitoylation of a Novel Site in the β2-Adrenergic Receptor Associated with a Novel Intracellular Itinerary*
N. Adachi, D. Hess, Precious J McLaughlin, J. Stamler
2016Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Protein kinase Cε: function in neurons
Y. Shirai, N. Adachi, N. Saito
2008The FEBS Journal55 citations
Semantic Scholar
Aggregate formation of mutant protein kinase C gamma found in spinocerebellar ataxia type 14 impairs ubiquitin‐proteasome system and induces endoplasmic reticulum stress
T. Seki, Hideyuki Takahashi, N. Adachi, Nana Abe +3 more
2007European Journal of Neuroscience55 citations
Semantic Scholar
Age-related changes of dietary intake and blood eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid levels in Japanese men and women.
T. Kawabata, Satoko Hirota, Tomoko Hirayama, N. Adachi +6 more
2011Prostaglandins, Leukotrienes and Essential Fatty Acids54 citations
Semantic Scholar
Importance of chroman ring and tyrosine phosphorylation in the subtype‐specific translocation and activation of diacylglycerol kinase α by d‐α‐tocopherol
Rika Fukunaga-Takenaka, Y. Shirai, K. Yagi, N. Adachi +4 more
200553 citations Open access
Semantic Scholar
DISTRIBUTION IN RELATION TO LIFE HISTORY IN THE DIRECT-DEVELOPING GASTROPOD BATILLARIA CUMINGI (BATILLARIIDAE) ON TWO SHORES OF CONTRASTING SUBSTRATA
N. Adachi, K. Wada
199944 citations Open access
Semantic Scholar
Immunocytochemical localization of a neuron-specific diacylglycerol kinase β and γ in the developing rat brain
N. Adachi, M. Oyasu, T. Taniguchi, Y. Yamaguchi +3 more
200541 citations
Semantic Scholar
Diacylglycerol kinase β accumulates on the perisynaptic site of medium spiny neurons in the striatum
Y. Hozumi, M. Fukaya, N. Adachi, N. Saito +4 more
2008European Journal of Neuroscience37 citations
Semantic Scholar
Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein.
Hideyuki Takahashi, N. Adachi, T. Shirafuji, S. Danno +10 more
2015Human Molecular Genetics28 citations
Semantic Scholar
Low-dose arachidonic acid intake increases erythrocytes and plasma arachidonic acid in young women.
Satoko Hirota, N. Adachi, T. Gomyo, H. Kawashima +2 more
2010Prostaglandins, Leukotrienes and Essential Fatty Acids27 citations
Semantic Scholar
Effect of Trehalose on the Properties of Mutant γPKC, Which Causes Spinocerebellar Ataxia Type 14, in Neuronal Cell Lines and Cultured Purkinje Cells*
T. Seki, Nana Abe-Seki, T. Kikawada, Hideyuki Takahashi +6 more
2010Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Xeroderma pigmentosum group C protein interacts with histones: regulation by acetylated states of histone H3
Erina Kakumu, Seiya Nakanishi, Hiromi M. Shiratori, Akari Kato +11 more
2017Genes to Cells26 citations Open access
Semantic Scholar
Associations between dietary n-6 and n-3 fatty acids and arachidonic acid compositions in plasma and erythrocytes in young and elderly Japanese volunteers
T. Kawabata, Satoko Hirota, Tomoko Hirayama, N. Adachi +6 more
2011Lipids in Health and Disease26 citations Open access
Semantic Scholar
Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy
Kazuhiro Yamamoto, T. Seki, N. Adachi, Tetsuya Takahashi +4 more
2010Genes to Cells23 citations Open access
Semantic Scholar
One-year follow-up study on associations between dental caries, periodontitis, and metabolic syndrome.
N. Adachi, Yasuki Kobayashi
2020Journal of Oral Science21 citations Open access
Semantic Scholar
Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene.
T. Shirafuji, H. Shimazaki, Tatsuhiro Miyagi, T. Ueyama +5 more
2019Molecular and cellular neurosciences21 citations
Semantic Scholar
S-palmitoylation of tyrosinase at cysteine500 regulates melanogenesis.
Y. Niki, N. Adachi, M. Fukata, Y. Fukata +11 more
2022Journal of Investigative Dermatology19 citations Open access
Semantic Scholar
S-nitrosylation is required for β2AR desensitization and experimental asthma
F. Fonseca, T. Raffay, K. Xiao, P. McLaughlin +13 more
2022Molecules and Cells18 citations Open access
Semantic Scholar
Insulin-Like Growth Factor-I Protects Against the Detrimental Effects of Advanced Glycation End Products and High Glucose in Myoblastic C2C12 Cells
N. Adachi, I. Kanazawa, Ken-ichiro Tanaka, Ayumu Takeno +3 more
2019Calcified Tissue International17 citations
Semantic Scholar
Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14
Kazuhiro Yamamoto, T. Seki, Hikaru Yamamoto, N. Adachi +4 more
2014Frontiers in Physiology17 citations Open access
Semantic Scholar
Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 14
Aoi Nakazono, N. Adachi, Hideyuki Takahashi, T. Seki +4 more
2018Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Elucidation of the molecular mechanism and exploration of novel therapeutics for spinocerebellar ataxia caused by mutant protein kinase Cγ.
T. Seki, N. Adachi, Nana Abe-Seki, Takayuki Shimahara +4 more
2011Journal of Pharmacological Sciences16 citations Open access
Semantic Scholar
Congo red, an amyloid-inhibiting compound, alleviates various types of cellular dysfunction triggered by mutant protein kinase cγ that causes spinocerebellar ataxia type 14 (SCA14) by inhibiting oligomerization and aggregation.
T. Seki, Hideyuki Takahashi, Kazuhiro Yamamoto, K. Ogawa +6 more
2010Journal of Pharmacological Sciences15 citations Open access
Semantic Scholar
Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.
Rika Fukunaga-Takenaka, Y. Shirai, K. Yagi, N. Adachi +4 more
2005Genes to Cells14 citations
Semantic Scholar
Immunocytochemical localization of a neuron-specific diacylglycerol kinase beta and gamma in the developing rat brain.
N. Adachi, M. Oyasu, T. Taniguchi, Y. Yamaguchi +3 more
2005Brain Research. Molecular Brain Research14 citations
Semantic Scholar
The Role of Cysteine String Protein α Phosphorylation at Serine 10 and 34 by Protein Kinase Cγ for Presynaptic Maintenance
T. Shirafuji, T. Ueyama, N. Adachi, K. Yoshino +8 more
2018Journal of Neuroscience13 citations Open access
Semantic Scholar
Mutant γPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity.
K. Ogawa, T. Seki, Tomoya Onji, N. Adachi +4 more
2013Biochemical and Biophysical Research Communications - BBRC13 citations
Semantic Scholar
Distribution of two intertidal gastropods, Batillaria multiformis and B. cumingi (Batillariidae) at a co-occurring area
N. Adachi
199812 citations
Semantic Scholar
The Role of Pak-Interacting Exchange Factor-β Phosphorylation at Serines 340 and 583 by PKCγ in Dopamine Release
T. Shirafuji, T. Ueyama, K. Yoshino, Hideyuki Takahashi +9 more
2014Journal of Neuroscience11 citations Open access
Semantic Scholar
Differential S-palmitoylation of the human and rodent β3-adrenergic receptors
N. Adachi, D. Hess, M. Kaku, Chie Ueda +2 more
2018Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Intake of trans fatty acid in Japanese university students.
T. Kawabata, Sachiko Shigemitsu, N. Adachi, Chie Hagiwara +4 more
2010Journal of Nutritional Science and Vitaminology10 citations Open access
Semantic Scholar
S-Palmitoylation of the serotonin transporter promotes its cell surface expression and serotonin uptake.
Kana Harada, Ryoma Sho, Hiromiki Takakura, E. Yokoyama +6 more
2023Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar
Thyroid crisis caused by metastatic thyroid cancer: an autopsy case report
Kai Takedani, M. Notsu, N. Adachi, Sayuri Tanaka +5 more
2021BMC Endocrine Disorders9 citations Open access
Semantic Scholar
Propofol induced diverse and subtype-specific translocation of PKC families.
Takeshi Miyahara, N. Adachi, T. Seki, Hideki D. Izumi +4 more
2018Journal of Pharmacological Sciences7 citations Open access
Semantic Scholar
Distribution of Batillaria cumingii (Gastropoda, Potamididae) in Tanabe Bay, middle Japan
N. Adachi
19977 citations
Semantic Scholar
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification
N. Adachi, D. Hess, Takehiko Ueyama
2025Journal of Lipid Research5 citations Open access
Semantic Scholar
R659S mutation of γPKC is susceptible to cell death: Implication of this mutation/polymorphism in the pathogenesis of retinitis pigmentosa
H. Mochizuki, T. Seki, N. Adachi, N. Saito +2 more
20065 citations
Semantic Scholar
Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities
Y. Hanaki, Masayuki Kikumori, H. Tokuda, M. Okamura +5 more
2017Molecules4 citations Open access
Semantic Scholar
Effects of flurbiprofen on the functional regulation of serotonin transporter and its misfolded mutant.
Haruki Hirakawa, K. Taguchi, Seiya Murakawa, M. Asano +8 more
2021Journal of Pharmacological Sciences2 citations Open access
Semantic Scholar
The effect of trehalose on the properties of mutant γPKC , which causes spinocerebellar ataxia type 14 ( SCA 14 ) , in neuronal cell lines and cultured Purkinje cells
T. Seki, Nana Abe-Seki, T. Kikawada, Hideyuki Takahashi +7 more
20121 citations
Semantic Scholar
A Study on Behavioral Changes of Patients with Diabetes Mellitus Before and After Diagnosis
Yukio Saitoh, Hiroko Shirai, Daisuke Hara, N. Adachi
20071 citations Open access
Semantic Scholar
Effects of mutant γPKC found in SCA14 on the nature of primary cultured Purkinje cells
T. Seki, Takayuki Shimahara, Nana Abe, Kazuhiro Yamamoto +4 more
20071 citations
Semantic Scholar
Late-onset Graves’ disease after hemithyroidectomy: a case report
Sayaka Mabuchi, N. Adachi, Atsushi Nagasawa, Satoshi Nabika +1 more
2026Journal of Medical Case Reports0 citations Open access
Semantic Scholar
Age‐Progressive Synaptic and Axonal Dysregulation Induced by Purkinje Cell–Targeted AAV Expression of SCA14 PKCγ in Mice
N. Adachi, Izumi Koganemaru, Wan-Ying Feng, Naoya Matsushita +6 more
2025Journal of Neurochemistry0 citations
Semantic Scholar
Development of type 1 diabetes mellitus after nivolumab dose escalation: A case report
Sayaka Mabuchi, N. Adachi, Atsushi Nagasawa, Satoshi Nabika
2025Medicine0 citations Open access
Semantic Scholar
Global Regulation of Protein S-palmitoylation by Nitric Oxide
N. Adachi, D. Hess, Izumi Koganemaru, T. Ueyama +1 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Vitamin E induces palmitoylation of 67kDa laminin receptor by direct binding .
Seika Okamoto, Daiki Hayashi, N. Adachi, M. Varnavas +6 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar

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N. Saito×25
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N. Saito — researcher profile on SciRah
N. Sakai×23
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N. Sakai — researcher profile on SciRah
T. Seki×16
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T. Seki — researcher profile on SciRah
Shigeru Tanaka×11
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Hideyuki Takahashi

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Hideyuki Takahashi — researcher profile on SciRah

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Hideki D. Izumi×9

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Hideki D. Izumi — researcher profile on SciRah

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Kazuhiro Yamamoto×7

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Naoaki Saito×6

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Takayuki Shimahara×4

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Takayuki Shimahara — researcher profile on SciRah