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L. Gerstenfeld · SciRah

Researcher profile · Semantic Scholar

L. Gerstenfeld

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L. Gerstenfeld — researcher profile on SciRah

h-index: 66
Works: 174
Citations: 19K

Most-cited papers

Fracture healing: mechanisms and interventions
T. Einhorn, L. Gerstenfeld
2014Nature Reviews Rheumatology1,676 citations Open access
Semantic Scholar
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
K. Tsuji, Amitabha Bandyopadhyay, B. Harfe, K. Cox +5 more
2006Nature Genetics854 citations
Semantic Scholar
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
Ying Wang, C. Wan, L. Deng, Ximeng Liu +10 more
2007Journal of Clinical Investigation741 citations Open access
Semantic Scholar
Molecular Mechanisms Controlling Bone Formation during Fracture Healing and Distraction Osteogenesis
Z. S. AI-Aql, A. Alagl, D. Graves, L. Gerstenfeld +1 more
2008Journal of dentistry research700 citations Open access
Semantic Scholar
Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration
C. Wan, S. Gilbert, Ying Wang, Xue-Mei Cao +9 more
2008Proceedings of the National Academy of Sciences of the United States of America487 citations Open access
Semantic Scholar
Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.
Mani Alikhani, Z. Alikhani, Coy M Boyd, Christine M Maclellan +6 more
2007Bone362 citations Open access
Semantic Scholar
Micro-Computed Tomography Assessment of Fracture Healing: Relationships among Callus Structure, Composition, and Mechanical Function
E. Morgan, Zachary D. Mason, Karen B. Chien, Anthony. Pfeiffer +3 more
2008Bone276 citations Open access
Semantic Scholar
Mechanism of action and morphologic changes in the alveolar bone in response to selective alveolar decortication-facilitated tooth movement.
S. Baloul, L. Gerstenfeld, E. F. Morgan, Roberto S. Carvalho +2 more
2011American Journal of Orthodontics and Dentofacial Orthopedics216 citations
Semantic Scholar
Three-dimensional Reconstruction of Fracture Callus Morphogenesis
L. Gerstenfeld, Y. Alkhiary, E. A. Krall, Fred H. Nicholls +7 more
2006Journal of Histochemistry and Cytochemistry205 citations Open access
Semantic Scholar
Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized
D. Hunter, L. Gerstenfeld, G. Bishop, A. D. Davis +7 more
2009Arthritis Research & Therapy202 citations Open access
Semantic Scholar
TNF-α Mediates Diabetes-Enhanced Chondrocyte Apoptosis During Fracture Healing and Stimulates Chondrocyte Apoptosis Through FOXO1
Rayyan A. Kayal, Michelle F. Siqueira, Jazia A. Alblowi, J. McLean +5 more
2010Journal of Bone and Mineral Research162 citations Open access
Semantic Scholar
A2B Adenosine Receptor Promotes Mesenchymal Stem Cell Differentiation to Osteoblasts and Bone Formation in Vivo*
S. Carroll, N. Wigner, Nitin Kulkarni, Hillary A. Johnston-Cox +2 more
2012Journal of Biological Chemistry158 citations Open access
Semantic Scholar
Tendon Regeneration and Scar Formation: The Concept of Scarless Healing
L. Galatz, L. Gerstenfeld, E. Heber-Katz, S. Rodeo
2015Journal of Orthopaedic Research157 citations Open access
Semantic Scholar
Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment.
L. Gerstenfeld, M. Al-Ghawas, Y. Alkhiary, D. Cullinane +5 more
2007Journal of Bone and Joint Surgery. American volume155 citations
Semantic Scholar
High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing.
Jazia A. Alblowi, Rayyan A. Kayal, Michelle Siqueria, Erin McKenzie +7 more
2009American Journal of Pathology153 citations Open access
Semantic Scholar
Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment
Rayyan A. Kayal, Jazia A. Alblowi, Erin McKenzie, Nanarao Krothapalli +4 more
2008Bone138 citations Open access
Semantic Scholar
VEGF and bone cell signalling: an essential vessel for communication?
C. Clarkin, L. Gerstenfeld
2013Cell Biochemistry and Function135 citations
Semantic Scholar
Vascular Tissues Are a Primary Source of BMP2 Expression during Bone Formation Induced by Distraction Osteogenesis
Hidenori Matsubara, D. Hogan, E. Morgan, Douglas P. Mortolock +2 more
2012Bone134 citations Open access
Semantic Scholar
Direct percutaneous gene delivery to enhance healing of segmental bone defects.
O. Betz, V. Betz, A. Nazarian, C. Pilapil +5 more
2006Journal of Bone and Joint Surgery. American volume134 citations
Semantic Scholar
Mechanical stimulation alters tissue differentiation and molecular expression during bone healing
Kristy T. Salisbury Palomares, Ryan E. Gleason, Zachary D. Mason, D. Cullinane +3 more
2009Journal of Orthopaedic Research132 citations Open access
Semantic Scholar
Qualitative and quantitative differences between bone graft obtained from the medullary canal (with a Reamer/Irrigator/Aspirator) and the iliac crest of the same patient.
H. C. Sagi, Megan Young, L. Gerstenfeld, T. Einhorn +1 more
2012Journal of Bone and Joint Surgery. American volume124 citations
Semantic Scholar
Stimulation of fracture-healing with systemic intermittent parathyroid hormone treatment.
G. Barnes, S. Kakar, S. Vora, E. Morgan +2 more
2008Journal of Bone and Joint Surgery. American volume117 citations
Semantic Scholar
Transcriptional Analysis of Fracture Healing and the Induction of Embryonic Stem Cell–Related Genes
M. Bais, J. McLean, P. Sebastiani, Megan Young +5 more
2009PLoS ONE113 citations Open access
Semantic Scholar
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects
O. Betz, V. Betz, A. Nazarian, M. Egermann +5 more
2007Gene Therapy113 citations Open access
Semantic Scholar
Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism
Ko I. Kang, L. S. Coimbra, Chen Tian, Jazia A. Alblowi +5 more
2015Diabetologia108 citations Open access
Semantic Scholar
BMP2 Is Essential for Post Natal Osteogenesis but Not for Recruitment of Osteogenic Stem Cells
M. Bais, N. Wigner, Megan Young, R. Toholka +4 more
2009Bone102 citations Open access
Semantic Scholar
Autogenous regulation of a network of bone morphogenetic proteins (BMPs) mediates the osteogenic differentiation in murine marrow stromal cells.
C. Edgar, Vinay Chakravarthy, G. Barnes, S. Kakar +2 more
2007Bone100 citations Open access
Semantic Scholar
FOXO1 Modulates Osteoblast Differentiation
Michelle F. Siqueira, Stephen Flowers, Rupa Bhattacharya, D. Faibish +5 more
2011Bone93 citations Open access
Semantic Scholar
TNFα Contributes to Diabetes Impaired Angiogenesis in Fracture Healing
Jason Lim, Kang I. Ko, Marcelo Mattos, Miao Fang +9 more
2017Bone89 citations Open access
Semantic Scholar
Expression and Role of Interleukin-6 in Distraction Osteogenesis
T. Cho, J. Kim, C. Chung, W. Yoo +3 more
2007Calcified Tissue International70 citations
Semantic Scholar
Chemokine Expression is Upregulated in Chondrocytes in Diabetic Fracture Healing
Jazia A. Alblowi, Chen Tian, Michelle F. Siqueira, Rayyan A. Kayal +5 more
2012Bone69 citations Open access
Semantic Scholar
Genetic Variation in the Patterns of Skeletal Progenitor Cell Differentiation and Progression During Endochondral Bone Formation Affects the Rate of Fracture Healing
K. J. Jepsen, C. Price, L. Silkman, Fred H. Nicholls +8 more
2008Journal of Bone and Mineral Research66 citations Open access
Semantic Scholar
Effects of OP‐1 and PTH in a new experimental model for the study of metaphyseal bone healing
E. Tsiridis, E. F. Morgan, J. Bancroft, Michael Song +5 more
2007Journal of Orthopaedic Research59 citations Open access
Semantic Scholar
Overview of Fracture Healing and Its Assessment
E. Morgan, Anthony F. De Giacomo, L. Gerstenfeld
2014Methods in molecular biology57 citations Open access
Semantic Scholar
Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression.
Kevin R Wang, P. Vishwanath, Gabriel S. Eichler, Maisa O. Al-Sebaei +4 more
2006Matrix Biology53 citations
Semantic Scholar
Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis
Weam Alshenibr, Mustafa M. Tashkandi, Saqer F. Alsaqer, Yazeed Alkheriji +6 more
2017Arthritis Research & Therapy52 citations Open access
Semantic Scholar
Lysyl Oxidase-like-2 (LOXL2) Is a Major Isoform in Chondrocytes and Is Critically Required for Differentiation*
Mussadiq Iftikhar, P. Hurtado, M. Bais, N. Wigner +3 more
2010Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Combined effects of recombinant human BMP-7 (rhBMP-7) and parathyroid hormone (1-34) in metaphyseal bone healing.
E. F. Morgan, Zachary D. Mason, G. Bishop, A. D. Davis +3 more
2008Bone51 citations
Semantic Scholar
Colloidal-gold Immunocytochemical Localization of Osteopontin in Avian Eggshell Gland and Eggshell
M. Hincke, Yung-Ching Chien, L. Gerstenfeld, M. McKee
2008Journal of Histochemistry and Cytochemistry51 citations Open access
Semantic Scholar
Healing of Segmental Bone Defects by Direct Percutaneous Gene Delivery: Effect of Vector Dose
V. Betz, O. Betz, V. Glatt, L. Gerstenfeld +4 more
2007Human Gene Therapy51 citations
Semantic Scholar
Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells
Amelia H. Baker, J. Watt, Cassie Huang, L. Gerstenfeld +1 more
2015Chemical Research in Toxicology48 citations Open access
Semantic Scholar
Vascular Development during Distraction Osteogenesis Proceeds by Sequential Intramuscular Arteriogenesis Followed by Intraosteal Angiogenesis
E. Morgan, Amira I. Hussein, Bader Alawadhi, D. Hogan +6 more
2012Bone41 citations Open access
Semantic Scholar
Role of Fas and Treg Cells in Fracture Healing as Characterized in the Fas-Deficient (lpr) Mouse Model of Lupus
Maisa O. Al-Sebaei, Dana Daukss, Anna C. Belkina, S. Kakar +6 more
2014Journal of Bone and Mineral Research36 citations Open access
Semantic Scholar
Earliest Phases of Chondrogenesis are Dependent upon Angiogenesis during Ectopic Bone Formation in Mice
B. Bragdon, Stephanie Lam, Sherif Aly, Alexandra Femia +4 more
2017Bone33 citations Open access
Semantic Scholar
Intrinsic Sex-Linked Variations in Osteogenic and Adipogenic Differentiation Potential of Bone Marrow Multipotent Stromal Cells
B. Bragdon, Robert Burns, Amelia H. Baker, A. Belkina +4 more
2015Journal of Cellular Physiology33 citations Open access
Semantic Scholar
Acute Phosphate Restriction Leads to Impaired Fracture Healing and Resistance to BMP-2
N. Wigner, Hilary F. Luderer, Megan K. Cox, K. Sooy +2 more
2009Journal of Bone and Mineral Research33 citations Open access
Semantic Scholar
AMPK Downregulates ALK2 via Increasing the Interaction between Smurf1 and Smad6, leading to inhibition of in vitro Osteogenic Differentiation
Hui Lin, Ying Ying, Yuanyuan Wang, G. Wang +6 more
2017Biochimica et biophysica acta. Molecular cell research30 citations Open access
Semantic Scholar
URINE MATRIX METALLOPROTEINASES (MMPs) AS BIOMARKERS FOR THE PROGRESSION OF FRACTURE HEALING
N. Wigner, Nitin Kulkarni, Mark Yakavonis, Megan Young +4 more
2012Injury22 citations Open access
Semantic Scholar
Sex-linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice
Loai Alsofi, Eileen J. Daley, I. Hornstra, E. Morgan +5 more
2015Calcified Tissue International21 citations Open access
Semantic Scholar
Mouse Models in Orthopaedic Research: An Overview of Fracture, Marrow Ablation, and Distraction Osteogenesis
Kyle E. Lybrand, B. Bragdon, L. Gerstenfeld
2015Current Protocols in Mouse Biology21 citations Open access
Semantic Scholar

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Rayyan A. Kayal

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