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R. Lipinski · SciRah

Researcher profile · Semantic Scholar

R. Lipinski

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R. Lipinski — researcher profile on SciRah

h-index: 29
Works: 77
Citations: 2,391

Most-cited papers

Hedgehog signaling promotes prostate xenograft tumor growth.
Lian-Ming Fan, Carmen V. Pepicelli, Christian C. Dibble, Winnie Catbagan +9 more
2004Endocrinology287 citations
Semantic Scholar
Ethanol-Induced Face-Brain Dysmorphology Patterns Are Correlative and Exposure-Stage Dependent
R. Lipinski, P. Hammond, Shonagh K. O'Leary-Moore, Jacob J. Ament +13 more
2012PLoS ONE155 citations Open access
Semantic Scholar
Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.
R. Lipinski, P. Hutson, Paul W Hannam, Robert J Nydza +5 more
2008Toxicological Sciences146 citations Open access
Semantic Scholar
The Teratogenic Effects of Prenatal Ethanol Exposure Are Exacerbated by Sonic Hedgehog or Gli2 Haploinsufficiency in the Mouse
Henry W. Kietzman, Joshua L. Everson, K. Sulik, R. Lipinski
2014PLoS ONE115 citations Open access
Semantic Scholar
Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.
R. Lipinski, J. Gipp, Jingxian Zhang, Jason D. Doles +1 more
2006Experimental Cell Research105 citations
Semantic Scholar
A Simple and Reliable Method for Early Pregnancy Detection in Inbred Mice.
Galen W. Heyne, E. Plisch, Cal G. Melberg, E. Sandgren +2 more
2015Journal of the American Association for Laboratory Animal Science88 citations
Semantic Scholar
Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: phenotypic characterization and clinical implications
R. Lipinski, Chih-Wa Song, K. Sulik, Joshua L. Everson +4 more
2010Birth defects research. Clinical and molecular teratology86 citations Open access
Semantic Scholar
Functional compensation in Hedgehog signaling during mouse prostate development.
Jason D. Doles, Crist Cook, Xu-Dong Shi, Janine Valosky +2 more
2006Developmental Biology81 citations Open access
Semantic Scholar
Genome-wide Enrichment of De Novo Coding Mutations in Orofacial Cleft Trios.
Madison R. Bishop, Kimberly K. Diaz Perez, Miranda R. Sun, Samantha Ho +23 more
2020American Journal of Human Genetics73 citations Open access
Semantic Scholar
Magnetic Resonance-based imaging in animal models of Fetal Alcohol Spectrum Disorder
Shonagh K. O'Leary-Moore, Scott E. Parnell, R. Lipinski, K. Sulik
2011Neuropsychology Review72 citations Open access
Semantic Scholar
Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis
Joshua L. Everson, D. Fink, J. Yoon, E. Leslie +6 more
2017Development69 citations Open access
Semantic Scholar
Lack of demonstrable autocrine hedgehog signaling in human prostate cancer cell lines.
Jingxian Zhang, R. Lipinski, Aubie Shaw, J. Gipp +1 more
2007Journal of Urology65 citations
Semantic Scholar
Definition of Critical Periods for Hedgehog Pathway Antagonist-Induced Holoprosencephaly, Cleft Lip, and Cleft Palate
Galen W. Heyne, Cal G. Melberg, Padydeh Doroodchi, Kia F. Parins +4 more
2015PLoS ONE64 citations Open access
Semantic Scholar
Cohesin complex-associated holoprosencephaly.
P. Kruszka, Seth I. Berger, Valentina Casà, Mike R. Dekker +31 more
2019Brain : a journal of neurology63 citations Open access
Semantic Scholar
Serotonin regulates calcium homeostasis in lactation by epigenetic activation of hedgehog signaling.
J. Laporta, Kimberly P. Keil, S. Weaver, C. M. Cronick +6 more
2014Molecular Endocrinology54 citations Open access
Semantic Scholar
Genesis of Teratogen-induced Holoprosencephaly in Mice
R. Lipinski, Elizabeth A. Godin, Shonagh K. O'Leary-Moore, Scott E. Parnell +1 more
2010American Journal of Medical Genetics. Part C, Seminars in Medical Genetics54 citations Open access
Semantic Scholar
Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines
R. Lipinski, M. Bijlsma, J. Gipp, David J Podhaizer +1 more
2008BMC Cell Biology53 citations Open access
Semantic Scholar
Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations.
J. Hughes, Ebba Alkhunaizi, P. Kruszka, L. Pyle +26 more
2019American Journal of Human Genetics52 citations Open access
Semantic Scholar
Gene-environment interactions: aligning birth defects research with complex etiology.
Tyler G. Beames, R. Lipinski
2020Development39 citations Open access
Semantic Scholar
A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly.
P. Kruszka, Seth I. Berger, K. Weiss, Joshua L. Everson +5 more
2019American Journal of Human Genetics37 citations Open access
Semantic Scholar
Identification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signaling.
R. Lipinski, Emelyne Dengler, Mark W. Kiehn, R. Peterson +1 more
2007Toxicological Sciences33 citations
Semantic Scholar
Growth, morphogenesis, and differentiation during mouse prostate development in situ, in renal grafts, and in vitro
Jason D. Doles, C. Vezina, R. Lipinski, R. Peterson +1 more
2005The Prostate32 citations
Semantic Scholar
Identification of Hedgehog Signaling Inhibitors with Relevant Human Exposure by Small Molecule Screening
R. Lipinski, W. Bushman
2010Toxicology in Vitro31 citations Open access
Semantic Scholar
Sonic hedgehog signaling regulates the expression of insulin‐like growth factor binding protein‐6 during fetal prostate development
R. Lipinski, Crist Cook, D. Barnett, J. Gipp +2 more
2005Developmental Dynamics31 citations
Semantic Scholar
Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog Signaling and Forebrain and Face Morphogenesis in the Mouse: An in Vitro and in Vivo Study
Joshua L. Everson, Miranda R. Sun, D. Fink, Galen W. Heyne +8 more
2019Environmental Health Perspectives30 citations Open access
Semantic Scholar
Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model
Galen W. Heyne, Joshua L. Everson, Lydia J. Ansen-Wilson, Cal G. Melberg +5 more
2016Disease Models & Mechanisms30 citations Open access
Semantic Scholar
Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells
Jingxian Zhang, R. Lipinski, J. Gipp, Aubie Shaw +1 more
2009BMC Developmental Biology30 citations Open access
Semantic Scholar
Examining the developmental toxicity of piperonyl butoxide as a Sonic hedgehog pathway inhibitor
Kenneth S. Rivera-González, Tyler G. Beames, R. Lipinski
2020Chemosphere29 citations Open access
Semantic Scholar
Prenatal exposure to pesticides and risk for holoprosencephaly: a case-control study
Y. Addissie, P. Kruszka, Angela Troia, Z. Wong +5 more
2020Environmental Health29 citations Open access
Semantic Scholar
Human Germline Hedgehog Pathway Mutations Predispose to Fatty Liver
M. J. Guillen Sacoto, Ariel F. Martinez, Yu Abe, P. Kruszka +9 more
2017Journal of Hepatology29 citations Open access
Semantic Scholar
Characterization of Subtle Brain Abnormalities in a Mouse Model of Hedgehog Pathway Antagonist-Induced Cleft Lip and Palate
R. Lipinski, Hunter T. Holloway, Shonagh K. O'Leary-Moore, Jacob J. Ament +6 more
2014PLoS ONE23 citations Open access
Semantic Scholar
Gene-environment interactions in birth defect etiology: Challenges and opportunities
R. Lipinski, R. S. Krauss
2022Current Topics in Developmental Biology22 citations Open access
Semantic Scholar
Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model
Galen W. Heyne, Joshua L. Everson, Lydia J. Ansen-Wilson, Cal G. Melberg +5 more
2016Development22 citations
Semantic Scholar
FAT4 Identified as a Potential Modifier of Orofacial Cleft Laterality
Sarah W. Curtis, Daniel Chang, Miranda R. Sun, M. P. Epstein +8 more
2021medRxiv21 citations Open access
Semantic Scholar
Identifying environmental risk factors and gene-environment interactions in holoprosencephaly
Y. Addissie, Angela Troia, Z. Wong, Joshua L. Everson +5 more
2020Birth Defects Research21 citations Open access
Semantic Scholar
Sonic Hedgehog Signaling in Cranial Neural Crest Cells Regulates Microvascular Morphogenesis in Facial Development
Miranda R. Sun, Hannah M. Chung, Veronika Matsuk, D. Fink +4 more
2020Frontiers in Cell and Developmental Biology20 citations Open access
Semantic Scholar
Academic Achievement Among Children With Nonsyndromic Orofacial Clefts
S. Watkins, R. Meyer, A. Aylsworth, J. Marcus +4 more
2018The Cleft Palate-Craniofacial Journal20 citations
Semantic Scholar
Identification of sonic hedgehog-regulated genes and biological processes in the cranial neural crest mesenchyme by comparative transcriptomics
Joshua L. Everson, D. Fink, Hannah M. Chung, Miranda R. Sun +1 more
2018BMC Genomics19 citations Open access
Semantic Scholar
Developmental malformations resulting from high-dose maternal tamoxifen exposure in the mouse
Miranda R. Sun, Austin C Steward, Emma A. Sweet, Alexander A. Martin +1 more
2021PLoS ONE18 citations Open access
Semantic Scholar
Disruption of DNA methylation–mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice
C. Ulschmid, Miranda R. Sun, C. R. Jabbarpour, Austin C Steward +11 more
2024Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Peripartum Fluoxetine Reduces Maternal Trabecular Bone After Weaning and Elevates Mammary Gland Serotonin and PTHrP
S. Weaver, H. Fricke, Cynthia Xie, R. Lipinski +3 more
2018Endocrinology17 citations Open access
Semantic Scholar
Gene-Environment Interactions in Cortical Interneuron Development and Dysfunction: A Review of Preclinical Studies
Lydia J. Ansen-Wilson, R. Lipinski
2016Neurotoxicology16 citations Open access
Semantic Scholar
A forebrain undivided: Unleashing model organisms to solve the mysteries of holoprosencephaly
Yevgenya Grinblat, R. Lipinski
2019Developmental Dynamics14 citations Open access
Semantic Scholar
Coordinated D-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway
D. Fink, Miranda R. Sun, Galen W. Heyne, Joshua L. Everson +4 more
2017Cellular Signalling14 citations Open access
Semantic Scholar
Common basis for orofacial clefting and cortical interneuronopathy
Lydia J. Ansen-Wilson, Joshua L. Everson, D. Fink, Henry W. Kietzman +2 more
2018Translational Psychiatry12 citations Open access
Semantic Scholar
Diversity or decolonization? Searching for the tools to dismantle the ‘master’s house’
M. Arshad, Rachel S. Dada, C. Elliott, Iweta Kalinowska +7 more
2021London Review of Education11 citations Open access
Semantic Scholar
Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate
Kelsey Robinson, T. Mosley, Kenneth S. Rivera-González, C. R. Jabbarpour +17 more
2023medRxiv10 citations Open access
Semantic Scholar
A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development
Brian P. Johnson, Ross A Vitek, Molly M. Morgan, D. Fink +4 more
2021Frontiers in Cell and Developmental Biology7 citations Open access
Semantic Scholar
Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate
K. Robinson, T. Mosley, Kenneth S. Rivera-González, C. R. Jabbarpour +17 more
2023HGG advances6 citations Open access
Semantic Scholar
40th Annual David W Smith Workshop on Malformations and Morphogenesis: Abstracts of the 2019 Annual Meeting
Stephen R. Braddock, R. Lipinski, J. Carey
2020American Journal of Medical Genetics. Part A4 citations
Semantic Scholar

Frequent co-authors

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Joshua L. Everson×18
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Joshua L. Everson — researcher profile on SciRah
W. Bushman×12
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W. Bushman — researcher profile on SciRah
D. Fink×9
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D. Fink — researcher profile on SciRah
J. Gipp×7
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J. Gipp — researcher profile on SciRah

×7

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K. Sulik — researcher profile on SciRah

Galen W. Heyne×7

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Galen W. Heyne — researcher profile on SciRah

Miranda R. Sun×7

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Miranda R. Sun — researcher profile on SciRah

Lydia J. Ansen-Wilson×6

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Lydia J. Ansen-Wilson — researcher profile on SciRah

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P. Kruszka — researcher profile on SciRah

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M. Muenke — researcher profile on SciRah

Cal G. Melberg×5

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Cal G. Melberg — researcher profile on SciRah

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M. Marazita — researcher profile on SciRah