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S. Siddiqui · SciRah

Researcher profile · Semantic Scholar

S. Siddiqui

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S. Siddiqui — researcher profile on SciRah

h-index: 15
Works: 169
Citations: 887

Most-cited papers

New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents.
M. Nazir, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +7 more
2018Bioorganic chemistry (Print)69 citations
Semantic Scholar
Novel indole based hybrid oxadiazole scaffolds with N-(substituted-phenyl)butanamides: synthesis, lineweaver–burk plot evaluation and binding analysis of potent urease inhibitors
M. Nazir, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +5 more
2018RSC Advances25 citations Open access
Semantic Scholar
Synthesis and structure-activity relationship of tyrosinase inhibiting novel bi-heterocyclic acetamides: Mechanistic insights through enzyme inhibition, kinetics and computational studies.
Abdul Rehman Sadiq Butt, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +5 more
2019Bioorganic chemistry (Print)24 citations
Semantic Scholar
Synthesis, molecular docking, dynamic simulations, kinetic mechanism, cytotoxicity evaluation of N-(substituted-phenyl)-4-{(4-[(E)-3-phenyl-2-propenyl]-1-piperazinyl} butanamides as tyrosinase and melanin inhibitors: In vitro, in vivo and in silico approaches.
H. Raza, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +6 more
2019Bioorganic chemistry (Print)22 citations
Semantic Scholar
Synthesis and structure-activity relationship of elastase inhibiting novel ethylated thiazole-triazole acetamide hybrids: Mechanistic insights through kinetics and computational contemplations.
Abdul Rehman Sadiq Butt, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +4 more
2019Bioorganic chemistry (Print)21 citations
Semantic Scholar
Synthesis, in vitro and in silico studies of novel potent urease inhibitors: N-[4-({5-[(3-Un/substituted-anilino-3-oxopropyl)sulfanyl]-1,3,4-oxadiazol-2-yl}methyl)-1,3-thiazol-2-yl]benzamides.
M. Abbasi, Mubashir Hassan, Aziz-ur-Rehman, S. Siddiqui +3 more
2018Bioorganic & Medicinal Chemistry21 citations Open access
Semantic Scholar
Exploration of synthetic multifunctional amides as new therapeutic agents for Alzheimer's disease through enzyme inhibition, chemoinformatic properties, molecular docking and dynamic simulation insights.
Mubashir Hassan, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +4 more
2018Journal of Theoretical Biology21 citations
Semantic Scholar
Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1,2,4‐Triazole‐3‐thiol: Synthesis and In Silico Molecular Study
S. Siddiqui, M. Arfan, M. Abbasi, Aziz-ur-Rehman +6 more
202018 citations
Semantic Scholar
Microwave‐assisted synthesis of triazole derivatives conjugated with piperidine as new anti‐enzymatic agents
N. Virk, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +7 more
2019Journal of Heterocyclic Chemistry15 citations
Semantic Scholar
Designing of promising medicinal scaffolds for Alzheimer's disease through enzyme inhibition, lead optimization, molecular docking and dynamic simulation approaches.
Mubashir Hassan, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +8 more
2019Bioorganic chemistry (Print)14 citations
Semantic Scholar
Design, synthesis and computational studies of N-(substituted-phenyl)-4-(4-phenyl-1-piperazinyl)butanamides as potent anti-melanogenic and tyrosinase inhibitors
H. Raza, M. Abbasi, A. Rehman, S. Siddiqui +5 more
2020Journal of Molecular Structure13 citations
Semantic Scholar
Synthesis, enzyme inhibitory kinetics mechanism and computational study of N-(4-methoxyphenethyl)-N-(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer’s disease
M. Abbasi, Mubashir Hassan, Aziz-ur-Rehman, S. Siddiqui +3 more
2018PeerJ13 citations Open access
Semantic Scholar
Synthesis, biological analysis and computational studies of substituted 1,2,4-triazoles: FMO, MEP and docking investigations
Zeeshan Munir, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +7 more
2025Journal of Molecular Structure12 citations Open access
Semantic Scholar
Bi‐heterocyclic benzamides as alkaline phosphatase inhibitors: Mechanistic comprehensions through kinetics and computational approaches
M. Abbasi, M. Nazir, A. ur-Rehman, S. Siddiqui +5 more
2019Archiv der Pharmazie12 citations
Semantic Scholar
Synthesis of new heterocyclic 3-piperidinyl-1,3,4-oxadiazole derivatives as potential drug candidate for the treatment of Alzheimer’s disease
A. Rehman, K. Nafeesa, M. Abbasi, S. Siddiqui +3 more
201812 citations Open access
Semantic Scholar
Multi-step synthesis of indole-N-ethyltriazole hybrids amalgamated with N-arylated ethanamides: structure-activity relationship and mechanistic explorations through tyrosinase inhibition, kinetics and computational ascriptions
Shakila, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +6 more
2022Journal of Molecular Structure11 citations
Semantic Scholar
2-Furoic piperazide derivatives as promising drug candidates of type 2 diabetes and Alzheimer's diseases: In vitro and in silico studies
M. Abbasi, Mubashir Hassan, A. ur-Rehman, S. Siddiqui +5 more
2018Comput. Biol. Chem.10 citations
Semantic Scholar
Compounds with 1,3,4-oxadiazole and azinane appendages to evaluate enzymes inhibition applications supported by docking and BSA binding
A. Rehman, J. Iqbal, M. Abbasi, S. Siddiqui +5 more
20189 citations Open access
Semantic Scholar
Synthesis, Kinetics, Binding Conformations and Structure-activity Relationship of Potent Tyrosinase Inhibitors: Aralkylated 2-aminothiazole-ethyltriazole Hybrids
Abdul Rehman Sadiq Butt, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +4 more
2021Iranian journal of pharmaceutical research8 citations
Semantic Scholar
Synthesis, In Vitro, and In Silico Studies of N-(Substituted-Phenyl)-3-(4-Phenyl-1-Piperazinyl)propanamides as Potent Alkaline Phosphatase Inhibitors
M. Abbasi, M. Nazir, Aziz-ur-Rehman, S. Siddiqui +4 more
2021Russian journal of bioorganic chemistry8 citations
Semantic Scholar
Comparative conventional and microwave assisted synthesis of heterocyclic oxadiazole analogues having enzymatic inhibition potential
Jamila Javid, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +8 more
20208 citations
Semantic Scholar
New piperidinyl heterocyclic azoles acquired through Li(I)-catalyzed reactions: Anti-enzymatic, ADME and computational studies
Sujhla Hamid, Hira Amjad, M. Abbasi, S. Siddiqui +8 more
2024Journal of Molecular Structure7 citations
Semantic Scholar
Convergent synthesis, free radical scavenging, Lineweaver‐Burk plot exploration, hemolysis and in silico study of novel indole‐phenyltriazole hybrid bearing acetamides as potent urease inhibitors
Wajiha Khan, M. Abbasi, A. Rehman, S. Siddiqui +6 more
20207 citations
Semantic Scholar
Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and BSA binding studies
J. Iqbal, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +8 more
20207 citations Open access
Semantic Scholar
Design of potent tyrosinase inhibiting N-arylated-4-yl-benzamides bearing 2-aminothiazole-triazole bi-heterocycles: mechanistic insight through enzyme inhibition, kinetics and computational studies
F. Khan, M. Abbasi, Aziz-Ur Rehman, S. Siddiqui +6 more
2024RSC Advances6 citations Open access
Semantic Scholar
In Vitro and In Silico Assessment of Bioactivity Properties and Pharmacokinetic Studies of New 3,5-Disubstituted-1,2,4-Triazoles
Hira Amjad, M. Abbasi, S. Siddiqui, Javed Iqbal +9 more
2022Journal of Molecular Structure6 citations
Semantic Scholar
Convergent synthesis of carbonic anhydrase inhibiting bi‐heterocyclic benzamides: Structure–activity relationship and mechanistic explorations through enzyme inhibition, kinetics, and computational studies
F. Khan, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +6 more
20216 citations
Semantic Scholar
Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl)acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study
M. Abbasi, Sajid Riaz, Aziz-ur-Rehman, S. Siddiqui +4 more
2019Brazilian Journal of Pharmaceutical Sciences6 citations Open access
Semantic Scholar
α-Glucosidase inhibitory potential and hemolytic evaluation of newly synthesized 3,4,5-trisubstituted-1,2,4-triazole derivatives.
K. Nafeesa, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +6 more
2019Pakistan Journal of Pharmaceutical Sciences6 citations
Semantic Scholar
Hypoglycemic, hepatoprotective and molecular docking studies of 5-[(4-chlorophenoxy) methyl]-1, 3, 4-oxadiazole-2-thiol
N. Shehzadi, K. Hussain, N. Bukhari, M. Islam +5 more
20186 citations Open access
Semantic Scholar
Conventional versus microwave assisted synthesis, molecular docking and enzyme inhibitory activities of new 3,4,5-trisubstituted-1,2,4-triazole analogues.
N. Virk, A. Rehman, M. Abbasi, S. Siddiqui +6 more
2018Pakistan Journal of Pharmaceutical Sciences6 citations Open access
Semantic Scholar
Enzyme inhibitory, Antifungal, Antibacterial and hemolytic potential of various fractions of Colebrookia oppositifolia.
T. Riaz, M. Abbasi, A. Rehman, S. Siddiqui +6 more
2017Pakistan Journal of Pharmaceutical Sciences6 citations Open access
Semantic Scholar
In vitro biological assessment of 1,3,4-oxadiazole sandwiched by azinane and acetamides supported by molecular docking and BSA binding studies
N. Virk, J. Iqbal, A. Aziz-ur-Rehman, M. Abbasi +7 more
2023Current Chemistry Letters5 citations Open access
Semantic Scholar
Design, synthesis of triazole-based scaffolds, N-(substitutedphenyl)-2-(5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthiol)acetamides: As potential anti-cholinesterase agents for neurodegenerative diseases
S. Siddiqui, M. Arfan, M. Abbasi, Aziz-ur-Rehman +6 more
2023Journal of Molecular Structure5 citations
Semantic Scholar
2‐Aminothiazole‐Oxadiazole Bearing N‐Arylated Butanamides: Convergent Synthesis, Tyrosinase Inhibition, Kinetics, Structure‐Activity Relationship, and Binding Conformations
Abdul Rehman Sadiq Butt, M. Abbasi, Aziz-Ur Rehman, S. Siddiqui +4 more
2023Chemistry and Biodiversity5 citations Open access
Semantic Scholar
Synthesis and Molecular Docking Studies of Novel Biheterocyclic Propanamides as Antidiabetic Agents Having Mild Cytotoxicity
M. Abbasi, K. Rubab, Aziz-ur-Rehman, S. Siddiqui +5 more
2023ACS Omega5 citations Open access
Semantic Scholar
Synthesis of Bi-heterocyclic Sulfonamides as Tyrosinase Inhibitors: Lineweaver-Burk Plot Evaluation and Computational Ascriptions.
M. Abbasi, Zia-ur Rehman, A. Rehman, S. Siddiqui +5 more
2020Acta Chimica Slovenica5 citations Open access
Semantic Scholar
Synthesis, in vitro and in silico studies of S-alkylated 5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazole-3-thiols as cholinesterase inhibitors.
M. Arfan, S. Siddiqui, M. Abbasi, A. Rehman +7 more
2018Pakistan Journal of Pharmaceutical Sciences5 citations Open access
Semantic Scholar
Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors
Abdul Rehman Sadiq Butt, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +6 more
2023RSC Advances4 citations Open access
Semantic Scholar
Modular and Computational Access to Innocuous Multistep Metal-Free Synthesis of 1,3,4-Oxadiazoles as Enzyme Inhibitors
M. Umair, A. ur Rehman, M. Abbasi, S. Siddiqui +5 more
2023ACS Omega4 citations Open access
Semantic Scholar
Biological screening and docking studies of unique hybrids synthesized by conventional versus microwave assisted techniques
N. Virk, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +7 more
20214 citations Open access
Semantic Scholar
S -substituted derivatives of 1,2,4-triazol-3-thiol as new drug candidates for type II diabetes
A. ur-Rehman, K. Nafeesa, M. Abbasi, S. Siddiqui +6 more
2018Turkish journal of chemistry4 citations Open access
Semantic Scholar
Radical Scavenging and Endogenous Defence System Inducing Activities of 5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazole-2-thiol: A Novel Antioxidant
N. Shehzadi, K. Hussain, M. T. Khan, N. Bukhari +7 more
20184 citations Open access
Semantic Scholar
in silico Study of Furocoumarins from Caryopteris odorata: Moderate Inhibitors of Butyryl Cholinesterase and Lipoxygenase
M. Abbasi, Ghulam Hussain, S. Siddiqui, V. Ahmad
20174 citations Open access
Semantic Scholar
Convergent Synthesis, Kinetics, and Computational Studies of Indole(Phenyl)Triazole Bi‐Heterocycles Modified With Propanamides as Elastase Inhibitors
Shakila, M. Abbasi, Aziz-ur-Rehman, S. Siddiqui +7 more
2024Chemistry and Biodiversity3 citations
Semantic Scholar
Multi-selective reaction of azinane bearing oxadiazoles and substituted haloalkanes catalyzed by alkali metal hydride to access anti-enzymatic agents
M. Umair, Aziz-ur-Rehman, M. Abbasi, S. Siddiqui +4 more
2023Journal of Molecular Structure3 citations
Semantic Scholar
Synthesis of 2-[2,3-dihydro-1,4-benzodioxin-6-yl(phenylsulfonyl)amino]-N-(un/substituted-phenyl)acetamides as anti-diabetic agents
M. Abbasi, Sobia Parveen, Aziz-ur-Rehman, S. Siddiqui +3 more
2023Tropical Journal of Pharmaceutical Research3 citations Open access
Semantic Scholar
BSA Binding, molecular docking and in vitro biological screening of some new 1, 2, 4-triazole heterocycles bearing azinane nucleus.
J. Iqbal, A. Rehman, M. Abbasi, S. Siddiqui +5 more
2020Pakistan Journal of Pharmaceutical Sciences3 citations
Semantic Scholar
Novel Bi-heterocycles as Potent Inhibitors of Urease and Less Cytotoxic Agents: 3-({5-((2-Amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol-2-yl}sulfanyl)-N-(un/substituted-phenyl)propanamides
M. Abbasi, M. Ramzan, Aziz-Ur Rehman, S. Siddiqui +4 more
2020Iranian journal of pharmaceutical research3 citations
Semantic Scholar
Structure-activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives
M. Abbasi, M. Ramzan, A. Aziz-ur-Rehman, S. Siddiqui +5 more
2019Journal of the Serbian Chemical Society3 citations Open access
Semantic Scholar

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