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Christine Mehner · SciRah

Researcher profile · Semantic Scholar

Christine Mehner

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Christine Mehner — researcher profile on SciRah

h-index: 15
Works: 29
Citations: 1,049

Most-cited papers

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer
Christine Mehner, Alexandra Hockla, Erin Miller, S. Ran +2 more
2014OncoTarget363 citations Open access
Semantic Scholar
Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma
Christine Mehner, Erin Miller, A. Nassar, W. Bamlet +2 more
2015Genes & cancer93 citations Open access
Semantic Scholar
A 3D‐Bioprinted Vascularized Glioblastoma‐on‐a‐Chip for Studying the Impact of Simulated Microgravity as a Novel Pre‐Clinical Approach in Brain Tumor Therapy
G. Silvani, Carin Basirun, Hanjie Wu, Christine Mehner +3 more
2021Advances in Therapy66 citations Open access
Semantic Scholar
Platelet-Derived Growth Factor Regulates YAP Transcriptional Activity via Src Family Kinase Dependent Tyrosine Phosphorylation
R. Smoot, N. Werneburg, Takaaki Sugihara, Matthew C. Hernandez +6 more
2017Journal of Cellular Biochemistry64 citations Open access
Semantic Scholar
Tumor Cell-derived MMP-3 Orchestrates Rac1b and Tissue Alterations that Promote Pancreatic Adenocarcinoma
Christine Mehner, Erin Miller, Davitte Khauv, A. Nassar +7 more
2014Molecular Cancer Research62 citations Open access
Semantic Scholar
EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review
Christine Mehner, A. Oberg, Krista M. Goergen, K. Kalli +7 more
2017Genes & cancer61 citations Open access
Semantic Scholar
PEGylation Extends Circulation Half-Life While Preserving In Vitro and In Vivo Activity of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1)
J. Batra, Jessica Robinson, Christine Mehner, Alexandra Hockla +3 more
2012PLoS ONE59 citations Open access
Semantic Scholar
Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes
J. Batra, A. Soares, Christine Mehner, E. Radisky
2013PLoS ONE44 citations Open access
Semantic Scholar
Triggering the landslide: the tumor-promotional effects of myofibroblasts
Christine Mehner, D. Radisky
2013Experimental Cell Research35 citations Open access
Semantic Scholar
Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers
Christine Mehner, A. Oberg, K. Kalli, A. Nassar +12 more
2015OncoTarget33 citations Open access
Semantic Scholar
PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma
Honghai Ma, Alexandra Hockla, Christine Mehner, Matt Coban +3 more
2019Scientific Reports32 citations Open access
Semantic Scholar
Targeting an autocrine IL-6 – SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma
Christine Mehner, Erin Miller, Alexandra Hockla, Matt Coban +3 more
2020Oncogene29 citations Open access
Semantic Scholar
Bad Tumors Made Worse: SPINK1
Christine Mehner, E. Radisky
2019Front. Cell Dev. Biol.25 citations Open access
Semantic Scholar
MYC is a crucial mediator of TGFβ-induced invasion in basal breast cancer
Magdalena A. Cichon, Megan Moruzzi, Tiziana A. Shqau, Erin Miller +5 more
2016Cancer Research17 citations Open access
Semantic Scholar
Testing 3D printed biological platform for advancing simulated microgravity and space mechanobiology research
G. Silvani, P. Bradbury, Carin Basirun, Christine Mehner +3 more
2022npj Microgravity15 citations Open access
Semantic Scholar
NanoString-based breast cancer risk prediction for women with sclerosing adenosis
S. Winham, Christine Mehner, E. Heinzen, Brendan T. Broderick +15 more
2017Breast Cancer Research and Treatment15 citations Open access
Semantic Scholar
Protocol for generation of multicellular spheroids through reduced gravity
Dylan A. Zinn, Christine Mehner, T. Patel
2023STAR Protocols10 citations Open access
Semantic Scholar
Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma
Christine Mehner, Alexandra Hockla, Matt Coban, B. Madden +3 more
2022Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Bacterial Virulence and Prevention for Human Spaceflight
H. Wazir, P. Narang, G. Silvani, Christine Mehner +3 more
2023Life6 citations Open access
Semantic Scholar
Real versus simulated galactic cosmic radiation for investigating cancer risk in the hematopoietic system - are we comparing apples to apples?
Christine Mehner, S. Krishnan, J. Chou, M. Freeman +3 more
2021Life sciences and space research6 citations
Semantic Scholar
Therapeutic biliary stents: applications and opportunities
M. Ledenko, B. Toskich, Christine Mehner, Hakan Ceylan +1 more
2024Expert Review of Medical Devices2 citations
Semantic Scholar
Testing 3D printed biological platform for advancing simulated microgravity and space mechanobiology research
G. Silvani, P. Bradbury, Carin Basirun, Christine Mehner +3 more
2022npj Microgravity2 citations Open access
Semantic Scholar
Abstract 5069: Engineering TIMP-1 for selective MMP inhibition and future use as a protein therapeutic.
Christine Mehner, J. Batra, Jessica Robinson, D. Radisky +1 more
20131 citations
Semantic Scholar
PRSS23 promotes ovarian cancer peritoneal dissemination independent of protease activity
Sharoon Akhtar, Matt Coban, Erin N Miller, Alexandra Hockla +6 more
2026Journal of Biological Chemistry0 citations Open access
Semantic Scholar
Abstract 3758: Targeting ovarian cancer induced peritoneal carcinomatosis by inhibition of signaling axis between Interleukin-6 (IL-6) and serine protease inhibitor Kazal type 1 (SPINK1)
Christine Mehner, Erin Miller, Matt Coban, Alexandra Hockla +2 more
2019Tumor Biology0 citations Open access
Semantic Scholar
Abstract 442: Serine protease inhibitor Kazal type 1 (SPINK1) drives anoikis resistance in ovarian clear cell carcinoma
Christine Mehner, Matt Coban, Alexandra Hockla, D. Radisky +1 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 4253: Expression profiling of paired benign and breast cancer lesions in African American women
A. Holowatyj, J. Ruterbusch, R. Ali-Fehmi, S. Bandyopadhyay +5 more
20170 citations
Semantic Scholar
Identifying a serine protease network involved in ovarian cancer progression using activity‐based protein profiling (ABPP)
Christine Mehner, Alexandra Hockla, D. Radisky, Evette S. Radisky
2017The FASEB Journal0 citations Open access
Semantic Scholar
Abstract 1497: Matrix metalloproteinase-9 mediates growth, invasion, and metastasis of human breast cancer cells
Christine Mehner, Erin Miller, D. Radisky, E. Radisky
20110 citations
Semantic Scholar

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