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S. Edwards · SciRah

Researcher profile · Semantic Scholar

S. Edwards

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S. Edwards — researcher profile on SciRah

h-index: 17
Works: 50
Citations: 931

Most-cited papers

Oxycodone and morphine have distinctly different pharmacological profiles: Radioligand binding and behavioural studies in two rat models of neuropathic pain
C. Nielsen, F. B. Ross, S. Lotfipour, K. Saini +2 more
2007Pain192 citations
Semantic Scholar
Small molecule angiotensin II type 2 receptor (AT₂R) antagonists as novel analgesics for neuropathic pain: comparative pharmacokinetics, radioligand binding, and efficacy in rats.
Maree T. Smith, B. Wyse, S. Edwards
2013Pain medicine (Malden, Mass.)97 citations Open access
Semantic Scholar
SEX DIFFERENCES IN THE PHARMACOKINETICS, OXIDATIVE METABOLISM AND ORAL BIOAVAILABILITY OF OXYCODONE IN THE SPRAGUE‐DAWLEY RAT
S. Chan, S. Edwards, B. Wyse, Maree T. Smith
2008Clinical and Experimental Pharmacology and Physiology69 citations
Semantic Scholar
Tissue uptake of ketamine and norketamine enantiomers in the rat: indirect evidence for extrahepatic metabolic inversion.
S. Edwards, Laurence E. Mather
2001Life Science41 citations
Semantic Scholar
Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models of Alzheimer's disease
S. Edwards, A. Hamlin, Nicola Marks, E. Coulson +1 more
2014Clinical and Experimental Pharmacology and Physiology39 citations
Semantic Scholar
Simultaneous determination of morphine, oxycodone, morphine-3-glucuronide, and noroxycodone concentrations in rat serum by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
S. Edwards, Maree T. Smith
2005Journal of chromatography. B, Analytical technologies in the biomedical and life sciences36 citations
Semantic Scholar
ANTINOCICEPTION VERSUS SERUM CONCENTRATION RELATIONSHIPS FOLLOWING ACUTE ADMINISTRATION OF INTRAVENOUS MORPHINE IN MALE AND FEMALE SPRAGUE‐DAWLEY RATS: DIFFERENCES BETWEEN THE TAIL FLICK AND HOT PLATE NOCICEPTIVE TESTS
S. South, S. Edwards, Maree T. Smith
2009Clinical and Experimental Pharmacology and Physiology35 citations
Semantic Scholar
Comparison of the Pharmacokinetics of Oxycodone and Noroxycodone in Male Dark Agouti and Sprague–Dawley Rats: Influence of Streptozotocin-Induced Diabetes
Lillian Huang, S. Edwards, Maree T. Smith
2005Pharmaceutical Research29 citations
Semantic Scholar
Glutamate and Kynurenate in the Rat Central Nervous System Following Treatments with Tail Ischaemia or Diclofenac
S. Edwards, Laurence E. Mather, Yi-Guang Lin, I. Power +1 more
2000The Journal of pharmacy and pharmacology28 citations
Semantic Scholar
Suppression of central noradrenergic neuronal activity inhibits hyperglycemia.
G. Smythe, S. Edwards
1992American Journal of Physiology28 citations
Semantic Scholar
Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
S. Edwards, Maree T. Smith
2007Journal of chromatography. B, Analytical technologies in the biomedical and life sciences24 citations
Semantic Scholar
Concurrent ketamine and alfentanil administration: pharmacokinetic considerations.
S. Edwards, C. F. Minto, Laurence E. Mather
2002British Journal of Anaesthesia24 citations Open access
Semantic Scholar
A role for central postsynapticα2-adrenoceptors in glucoregulation
G. Smythe, S. Edwards
199124 citations
Semantic Scholar
Effects of diclofenac in the rat tail ischaemia–reperfusion injury model of acute hyperalgesia
R. Grace, Yi-Guang Lin, S. Edwards, I. Power +1 more
2001Pain22 citations
Semantic Scholar
The involvement of dopamine D1 and D2 receptors in the locomotor stimulation produced by (+)-amphetamine in naive and dopamine-depleted mice.
S. Ross, David M. Jackson, S. Edwards
1989Acta Pharmacologica et Toxicologica19 citations
Semantic Scholar
Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure.
Maree T. Smith, B. Wyse, S. Edwards, M. El-Tamimy +2 more
2015Journal of Pharmacy and Science18 citations
Semantic Scholar
Neuropharmacology of delta-aminolaevulinic acid--I. Effect of acute administration in rodents.
S. Edwards, B. Shanley, J. Reynoldson
1984Neuropharmacology18 citations
Semantic Scholar
Electroencephalographic effects of thiopentone and its enantiomers in the rat.
L. Mather, S. Edwards, C. Duke
1999Life Science17 citations
Semantic Scholar
Neuropharmacology of δ-aminolaevulinic acid. II. Effect of chronic administration in mice
S. Edwards, D. Jackson, J. Reynoldson, B. Shanley
198416 citations
Semantic Scholar
Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A(2-17) following spinal and supraspinal routes of administration.
K. Hemstapat, L. Le, S. Edwards, Maree T. Smith
2009Pharmacology, Biochemistry and Behavior15 citations
Semantic Scholar
Enantioselectivity of thiopental distribution into the central neural tissue of rats: an interaction with halothane.
Laurence E. Mather, S. Edwards, C. Duke, Michael J. Cousins
1999Anesthesia and Analgesia15 citations Open access
Semantic Scholar
Electroencephalographic effects of thiopentone and its enantiomers in the rat: correlation with drug tissue distribution
Laurence E. Mather, S. Edwards, C. Duke
1999British Journal of Pharmacology14 citations Open access
Semantic Scholar
Microdialysis study of the blood-brain equilibration of thiopental enantiomers.
Laurence E. Mather, S. Edwards, C. Duke, Michael J. Cousins
2000British Journal of Anaesthesia12 citations Open access
Semantic Scholar
Central and peripheral tissue distribution of diclofenac after subcutaneous injection in the rat
R. Grace, S. Edwards, L. Mather, Yi-Guang Lin +1 more
2004InflammoPharmacology11 citations
Semantic Scholar
Diclofenac increases the accumulation of kynurenate following tryptophan pretreatment in the rat: a possible factor contributing to its antihyperalgesic effect
S. Edwards, L. Mather
2004InflammoPharmacology11 citations
Semantic Scholar
Dopamine D2 agonist-induced behavioural depression is reversed by dopamine D1 agonists
David M. Jackson, S. Ross, S. Edwards
2005Journal of neural transmission10 citations
Semantic Scholar
Oxycodone's mechanism of action and potency differences after spinal and systemic routes of administration.
Maree T. Smith, S. Edwards, C. Nielsen
2007Anesthesiology9 citations Open access
Semantic Scholar
Chirality in anaesthesia--ropivacaine, ketamine and thiopentone.
Laurence E. Mather, S. Edwards
1998Current Opinion in Anaesthesiology9 citations
Semantic Scholar
A role for central postsynaptic alpha 2-adrenoceptors in glucoregulation.
G. Smythe, S. Edwards
1991Brain Research9 citations
Semantic Scholar
Effects of C1-INH Treatment on Neurobehavioral Sequelae and Late Seizures After Traumatic Brain Injury in a Mouse Model of Controlled Cortical Impact
Min Chen, Q. Tieng, Jiaxin Du, S. Edwards +3 more
2023Neurotrauma Reports7 citations Open access
Semantic Scholar
Enhancement by a single dose of reserpine (plus alpha methyl-p-tyrosine) of the central stimulatory effects evoked by dopamine D-1 and D-2 agonists in the mouse
S. Ross, D. Jackson, E. Wallis, S. Edwards
1988Naunyn-Schmiedeberg's Archives of Pharmacology7 citations
Semantic Scholar
STUDIES WITH KETAMINE AND ALFENTANIL FOLLOWING FREUND'S COMPLETE ADJUVANT‐INDUCED INFLAMMATION IN RATS
S. Edwards, Laurence E. Mather, Maree T. Smith
2007Clinical and Experimental Pharmacology and Physiology6 citations
Semantic Scholar
Effects of a 5-HT3 antagonist on peripheral 5-hydroxytryptamine-induced anorexia
Robin Stevens, S. Edwards
1996Psychobiology6 citations Open access
Semantic Scholar
Neuropharmacology of delta-aminolaevulinic acid. II. Effect of chronic administration in mice.
S. Edwards, D. Jackson, J. Reynoldson, B. Shanley
1984Neuroscience Letters6 citations
Semantic Scholar
Alfentanil potentiates anaesthetic and electroencephalographic responses to ketamine in the rat.
S. Edwards, L. Mather
2003European Journal of Pharmacology3 citations
Semantic Scholar
Original Small Molecule Angiotensin II Type 2 Receptor (AT 2 R) Antagonists as Novel Analgesics for Neuropathic Pain: Comparative Pharmacokinetics, Radioligand Binding, and Efﬁcacy in Rats
Maree T. Smith, B. Wyse, S. Edwards
20132 citations
Semantic Scholar
Oxycodone’s Mechanism of Action and Potency Differences after Spinal and Systemic Routes of Administration
Maree T. Smith, S. Edwards, C. Nielsen, K. Lemberg +6 more
20072 citations
Semantic Scholar
Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease
S. Edwards, Nemat Khan, E. Coulson, Maree T. Smith
2020Clinical and Experimental Pharmacology and Physiology1 citations
Semantic Scholar
TRANSLATIONAL RESEARCH SECTION Original Research Article Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonists as Novel Analgesics for Neuropathic Pain: Comparative Pharmacokinetics, Radioligand Binding, and Efficacy in Rats
Maree T. Smith, B. Wyse, S. Edwards
20160 citations
Semantic Scholar
A behavioural study assessing memory deficits in the APP/PS1 double transgenic mouse model of Alzheimer’s disease using the Morris water maze.
S. Edwards, E. Coulson, Maree T. Smith
20100 citations
Semantic Scholar
A study of the application of the Morris water maze to the establishment of a preclinical model of Alzheimer's disease in the rat
S. Edwards, Maree T. Smith
20090 citations
Semantic Scholar
Antihyperalgesic and anti-inflammatory effects of RS- & S-ketamine in freunds complete adjuvant (FCA)-induced inflammation
S. Edwards, L. Mather, Maree T. Smith
20050 citations
Semantic Scholar
Comparative pharmacokinetics and metabolism of subcutaneous oxycodone in male dark agouti relative to sprague-dawley rats
L. Huang, S. Edwards, Maree T. Smith
20040 citations
Semantic Scholar
Determination of morphine, oxycodone, morphine-3-glucuronide, & noroxycodone concentrations in rat serum by liquid chromatography (LC) - electrospray mass spectrometry (EMS)
S. Edwards, Maree T. Smith
20040 citations
Semantic Scholar
Quantification of morphine, oxycodone, morphine-3-glucuronide and noroxycodone in rat serum by high performance liquid chromatography (HPLC-electrospray mass spectrometry (EMS)
S. Edwards, Maree T. Smith
20030 citations
Semantic Scholar
Serum concentrations of metabolically-derived oxymorphone are insignificant in diabetic and non-diabetic adult male Dark Agouti rats following subcutaneous oxycodone bolus administration: Comparison with Sprague-Dawley rats
L. Huang, L. Le, S. Edwards, Maree T. Smith
20030 citations
Semantic Scholar
Central antinociceptive-analgesic effect of diclofenac
L. Mather, Yi-Guang Lin, S. Edwards
20020 citations
Semantic Scholar
Central antinociceptive-analgesic effect of diclofenac. Authors' reply
I. Jurna, L. Mather, Yi-Guang Lin, S. Edwards
20020 citations
Semantic Scholar
The systematics community
S. Edwards, G. M. Davis, L. I. Nevling
19850 citations Open access
Semantic Scholar
Systematics '75 : a report on a workshop assessing the current status of systematics collections
S. Edwards, Leonard D. Grotta
19760 citations Open access
Semantic Scholar

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