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C. Franchet · SciRah

Researcher profile · Semantic Scholar

C. Franchet

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C. Franchet — researcher profile on SciRah

h-index: 6
Works: 29
Citations: 347

Most-cited papers

Identification and pharmacological properties of E339–3D6, the first nonpeptidic apelin receptor agonist
X. Iturrioz, Rodrigo Alvear-Perez, N. De Mota, C. Franchet +12 more
2010The FASEB Journal106 citations
Semantic Scholar
Small Neutralizing Molecules to Inhibit Actions of the Chemokine CXCL12*
Muriel Hachet‐Haas, K. Balabanian, F. Rohmer, F. Pons +16 more
2008Journal of Biological Chemistry102 citations Open access
Semantic Scholar
Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties
B. Ilien, C. Franchet, P. Bernard, S. Morisset +4 more
2003Journal of Neurochemistry59 citations
Semantic Scholar
Chemical switch of a metabotropic glutamate receptor 2 silent allosteric modulator into dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulators.
S. Schann, S. Mayer, C. Franchet, Mélanie Frauli +4 more
2010Journal of Medicinal Chemistry49 citations Open access
Semantic Scholar
Development and Characterization of Antibodies Against the N Terminus of the Human Dopamine D4 Receptor
F. Lanau, M. Brockhaus, J. Pink, C. Franchet +4 more
1997Journal of Neurochemistry15 citations
Semantic Scholar
High-Throughput Screening of TRPV1 Ligands in the Light of the Bioluminescence Resonance Energy Transfer Technique
Y. Chappe, Pauline Michel, Alexandre Joushomme, S. Barbeau +12 more
2021Molecular Pharmacology8 citations Open access
Semantic Scholar
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies.
Mickael Fer, Camille Amalric, Roberto Arban, L. Baron +30 more
2024Journal of Medicinal Chemistry5 citations
Semantic Scholar
GPCR Binding Technologies: An Overview.
C. Franchet, Ismet B. Dorange
2015Current Topics in Medicinal Chemistry2 citations
Semantic Scholar
Discovery of DT-9081, a Potent and Orally Bioavailable Small Molecule Antagonist of the EP4 Receptor for the Treatment of Solid Cancers
Anne-Laure Blayo, G. Hommet, Mickael Fer, C. Halter +20 more
2026Journal of Medicinal Chemistry1 citations
Semantic Scholar
Targeting PAR-2 with a negative allosteric modulator increases tumor antigen presentation and potentiates anti-PD-1 immunotherapy
Samya Aouad, M. Kadiri, D. Allard, Emma Skora +14 more
2026Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar
Abstract 312: Comprehensive characterization of DT-7012, a differentiated CCR8-depleting antibody for the treatment of solid tumors
Hélène Lelièvre, Mélanie Frauli, M. D. García Fernández, Dounia Chraa +11 more
2025Cancer Research1 citations
Semantic Scholar
Abstract 4356: Comprehensive characterization of DT-7012, a highly differentiated anti-CCR8 depleting antibody
M. D. García Fernández, C. Franchet, L. Baron, Solène Rose +8 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 6157: PAR2 inhibitors reduce resistance to immunotherapy against cancer
T. Brugat, M. Kadiri, Samya Aouad, D. Allard +9 more
2025Cancer Research0 citations
Semantic Scholar
1324 Characterization of DT-7012, a highly differentiated anti-CCR8 mAb clinical candidate
Dounia Chraa, M. D. García Fernández, Alice Gentil Dit Maurin, I. Richert +15 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract 684: DT-9045, a novel PAR2 inhibitor with best-in-class properties that reduces resistance to both EGFR-targeting therapies and immunotherapy in oncology models
T. Brugat, M. Kadiri, Samya Aouad, Anne-Laure Blayo +17 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 4961: Novel biased PAR2 inhibitors with best-in-class properties reduce resistance to both chemotherapy and immunotherapy in oncology models
T. Brugat, Francesco Bergami, B. Rugeri, Aurélie Janvier +18 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 2946: Depleting hCCR8 mAb Therapy #1: Characterization of a broad collection of anti-hCCR8 mAbs
C. Vermot-Desroches, I. Richert, Malaury Schappler, A. Maurin +12 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 2945: Depleting hCCR8 mAb Therapy #2: Selection of candidates for the development of innovative depleting anti CCR8 therapeutic antibodies to control the immunosuppressive tumor microenvironment
I. Richert, Malaury Schappler, A. Maurin, Mégane Jeannelle +14 more
2023Cancer Research0 citations
Semantic Scholar
1393 Beyond CCR8 key epitopes targeting dynamic CCR8 conformational states and a diversity of monoclonal antibodies to modulate the tumor microenvironment for the treatment of cancers
C. Vermot-Desroches, I. Richert, Malaury Schappler, Alice Gentil Dit Maurin +11 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract LB123: A high value pharmacological platform dedicated to the real time study of stimulatory immune checkpoint signaling pathways
A. Maurin, C. Franchet, S. Schann, X. Leroy
2021Experimental and Molecular Therapeutics0 citations
Semantic Scholar
WITH MONOTHERAPY EFFICACY IN SYNGENEIC MOUSE MODEL(S) AND BEST-IN-CLASS PROPERTIES USING TUMOR TISSUE-DERIVED AND ARTIFICIALLY PRODUCED BACTERIAL OUTER MEMBRANE VESICLES
A. Blayo, Laurène Deshons, A. Dumont, C. Franchet +9 more
20200 citations
Semantic Scholar
Abstract 6697: DT095895, a selective EP4receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties
A. Blayo, Laurène Deshons, A. Dumont, C. Franchet +9 more
2020Immunology0 citations
Semantic Scholar
OP0236 RELEVANCE OF BIASED PAR2 INHIBITORS IN REDUCING INFLAMMATION AND CARTILAGE DEGRADATION IN IN VITRO AND IN VIVO MODELS OF RHEUMATOID ARTHRITIS
T. Brugat, B. Rugeri, G. Hommet, A. Dumont +12 more
2020Annals of the Rheumatic Diseases0 citations Open access
Semantic Scholar
Abstract 6308: Development of a pharmacological platform to study in real time immune checkpoints signaling pathways: validation with therapeutic mAbs and small molecules
A. Maurin, C. Franchet, X. Leroy, S. Schann
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
817 DT095895, a selective EP4 receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties
A. Blayo, Laurène Deshons, A. Dumont, C. Franchet +9 more
20200 citations Open access
Semantic Scholar
CHAPTER 4:Molecular Biology Techniques Applied to GPCR Allosteric and Biased Ligands
Mélanie Frauli, C. Franchet, Ismet B. Dorange, A. Mancini +2 more
20160 citations
Semantic Scholar
mGluR3 PAM: a novel neuroprotective strategy for Parkinson's disease
S. Schann, B. Manteau, S. Mayer, C. Franchet +7 more
20130 citations
Semantic Scholar
Identification and Characterization of E339-3D6, the First Nonpeptidic Apelin Receptor Agonist XAVIER ITURRIOZ
X. Itturioz, Rodrigo Alvear-Perez, N. De Mota, C. Franchet +12 more
20100 citations
Semantic Scholar
Collections of trackable links and use it
M. Hibert, C. Franchet, J. Galzi, F. Pattus +1 more
20050 citations
Semantic Scholar

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