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D. Rimmington · SciRah

Researcher profile · Semantic Scholar

D. Rimmington

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D. Rimmington — researcher profile on SciRah

h-index: 23
Works: 37
Citations: 3,047

Most-cited papers

GDF15 mediates the effects of metformin on body weight and energy balance
A. Coll, Michael Chen, Pranali Taskar, D. Rimmington +29 more
2019Nature485 citations Open access
Semantic Scholar
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans
Satish Patel, Anna Alvarez-Guaita, A. Melvin, D. Rimmington +32 more
2019Cell Metabolism429 citations Open access
Semantic Scholar
HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus
Lukas Steuernagel, Brian Y. H. Lam, Paul Klemm, G. Dowsett +15 more
2022Nature Metabolism233 citations Open access
Semantic Scholar
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity
Kevin D. Dalgaard, Kathrin Landgraf, Steffen Heyne, Adelheid M. Lempradl +26 more
2016Cell190 citations Open access
Semantic Scholar
GDF15 linked to maternal risk of nausea and vomiting during pregnancy
M. Fejzo, N. Rocha, I. Cimino, S. Lockhart +39 more
2023Nature172 citations Open access
Semantic Scholar
Role for the obesity-related FTO gene in the cellular sensing of amino acids
P. Gulati, M. Cheung, R. Antrobus, C. Church +11 more
2013Proceedings of the National Academy of Sciences of the United States of America172 citations Open access
Semantic Scholar
Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse
Fiona Mcmurray, C. Church, R. Larder, G. Nicholson +11 more
2013PLoS Genetics154 citations Open access
Semantic Scholar
Insulin-like peptide 5 is an orexigenic gastrointestinal hormone
J. Grosse, Helen Heffron, K. Burling, Mohammed Akhter Hossain +19 more
2014Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
Brian Y. H. Lam, I. Cimino, Joseph Polex-Wolf, Sara Nicole Kohnke +11 more
2017bioRxiv143 citations Open access
Semantic Scholar
MC3R links nutritional state to childhood growth and the timing of puberty
Brain Y. Lam, A. Williamson, S. Finer, F. Day +36 more
2021Nature118 citations Open access
Semantic Scholar
Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15
I. Cimino, Hanna Kim, Y. L. Loraine Tung, Kent Pedersen +24 more
2021Proceedings of the National Academy of Sciences of the United States of America93 citations Open access
Semantic Scholar
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome
Joseph Polex-Wolf, Brian Y. H. Lam, R. Larder, J. Tadross +9 more
2018Journal of Clinical Investigation92 citations Open access
Semantic Scholar
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
Ming Yang, Tamana Darwish, P. Larraufie, D. Rimmington +11 more
2021Scientific Reports91 citations Open access
Semantic Scholar
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing
G. Dowsett, Brian Y. H. Lam, J. Tadross, I. Cimino +6 more
2021Molecular Metabolism78 citations Open access
Semantic Scholar
The Effects of Neurokinin B upon Gonadotrophin Release in Male Rodents
M. Corander, B. Challis, E. Thompson, Z. Jovanović +10 more
2010Journal of neuroendocrinology75 citations Open access
Semantic Scholar
Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation
Rachel Larder, M. F. Michelle Sim, P. Gulati, R. Antrobus +13 more
2017Proceedings of the National Academy of Sciences of the United States of America61 citations Open access
Semantic Scholar
Pro-opiomelanocortin (POMC) modulates the thermogenic and physical activity responses to high fat feeding and markedly influences dietary fat preference
Y.C. Loraine Tung, D. Rimmington, S. O'Rahilly, A. Coll
2007Endocrinology51 citations Open access
Semantic Scholar
GDF15 antagonism limits severe heart failure and prevents cardiac cachexia
Minoru Takaoka, J. Tadross, Ali B A K Al-Hadithi, Xiaohui Zhao +14 more
2024Cardiovascular Research40 citations Open access
Semantic Scholar
Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol
T. Novoselova, R. Larder, D. Rimmington, C. Lelliott +9 more
2016Journal of Endocrinology38 citations Open access
Semantic Scholar
FTO is necessary for the induction of leptin resistance by high-fat feeding
Y. L. Loraine Tung, P. Gulati, Che-Hsiung Liu, D. Rimmington +6 more
2015Molecular Metabolism34 citations Open access
Semantic Scholar
Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty
S. Howard, L. Guasti, Ariel H. B. Poliandri, A. David +10 more
2017Journal of Clinical Endocrinology and Metabolism32 citations Open access
Semantic Scholar
Loss of Agouti-Related Peptide Does Not Significantly Impact the Phenotype of Murine POMC Deficiency
M. Corander, D. Rimmington, B. Challis, S. O'Rahilly +1 more
2011Endocrinology29 citations Open access
Semantic Scholar
Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity
Zheng-Zheng S. Liang, Irene Cimino, Binnaz Yalcin, N. Raghupathy +11 more
2020PLoS Genetics27 citations Open access
Semantic Scholar
Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health
S. Lockhart, Milan Muso, I. Zvetkova, Brian Y. H. Lam +38 more
2024Nature Metabolism20 citations Open access
Semantic Scholar
The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15
John W. R. Kincaid, D. Rimmington, J. Tadross, I. Cimino +6 more
2024Scientific Reports17 citations Open access
Semantic Scholar
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity
I. Cimino, D. Rimmington, Y. L. Loraine Tung, K. Lawler +16 more
2021Scientific Reports11 citations Open access
Semantic Scholar
Cross-species studies implicate the melanocortin 3 receptor more strongly in the control of pubertal development than energy balance
K. Duckett, Alyce McClellan, L. Corbin, I. Cimino +21 more
2025Molecular Metabolism6 citations Open access
Semantic Scholar
A survey of the mouse hindbrain in the fed and fasted state using single-nucleus RNA sequencing
G. Dowsett, Brian Y. H. Lam, J. Tadross, I. Cimino +6 more
2021bioRxiv5 citations Open access
Semantic Scholar
Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance
A. Coll, Michael Chen, Pranali Taskar, D. Rimmington +29 more
2020Nature5 citations Open access
Semantic Scholar
GDF15 and the beneficial actions of metformin in pre-diabetes
A. Coll, M. Chen, Pranali Taskar, D. Rimmington +24 more
2019bioRxiv2 citations Open access
Semantic Scholar
Loss and gain of function experiments implicate TMEM18 as a mediator of the strong association between genetic variants at human Chromosome 2p25.3 and obesity
R. Larder, M. F. Michelle Sim, P. Gulati, R. Antrobus +13 more
2017bioRxiv2 citations Open access
Semantic Scholar
Damaging mutations in Liver X Receptor-alpha (LXRa) are hepatotoxic and implicate cholesterol sensing in liver health
S. Lockhart, Milan Muso, I. Zvetkova, B. Lam +38 more
2 citations
Semantic Scholar
Damaging mutations in LXRα uncouple lipogenesis from hepatotoxicity and implicate hepatic cholesterol sensing in human liver health
S. Lockhart, Milan Muso, I. Zvetkova, B. Lam +37 more
2024bioRxiv1 citations Open access
Semantic Scholar
GDF15 antagonism limits severe heart failure and prevents cardiac cachexia in mice
M. Takaoka, J. Tadross, Ali B A K Al-Hadithi, R. Villena-Gutiérrez +13 more
2022bioRxiv1 citations Open access
Semantic Scholar
Damaging mutations in LXR[alpha] uncouple lipogenesis from hepatotoxicity and implicate hepatic cholesterol sensing in human liver health
S. Lockhart, Milan Muso, I. Zvetkova, B. Lam +36 more
2024Endocrine Abstracts0 citations
Semantic Scholar
Melanocortin 2 receptor accessory protein 2 (Mrap2) is associated with obesity and mediates hypothalamic melanocortin-4-receptor trafficking in vivo
T. Novoselova, R. Larder, D. Rimmington, C. Lelliott +6 more
20140 citations
Semantic Scholar
Melanocortin 2 receptor accessory protein 2 (Mrap2) regulates hypothalamic melanocortin-4-receptor trafficking in vivo
T. Novoselova, R. Larder, D. Rimmington, C. Lelliott +5 more
20140 citations
Semantic Scholar

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S. O'Rahilly×17
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