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C. Boddy · SciRah

Researcher profile · Semantic Scholar

C. Boddy

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C. Boddy — researcher profile on SciRah

h-index: 31
Works: 102
Citations: 3,713

Most-cited papers

Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics.
K. Nicolaou, C. Boddy, Stefan Bräse, N. Winssinger
1999Angewandte Chemie546 citations Open access
Semantic Scholar
Portable, On-Demand Biomolecular Manufacturing.
Keith Pardee, S. Slomovic, P. Q. Nguyen, Jeong Wook Lee +10 more
2016Cell321 citations Open access
Semantic Scholar
Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli
Kenji Watanabe, K. Hotta, Alex P. Praseuth, K. Koketsu +5 more
2006Nature Chemical Biology214 citations
Semantic Scholar
Extending synthetic access to proteins with a removable acyl transfer auxiliary.
J. Offer, C. Boddy, P. Dawson
2002Journal of the American Chemical Society212 citations
Semantic Scholar
Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?
Mark E. Horsman, Taylor P. A. Hari, C. Boddy
2016Natural product reports (Print)135 citations
Semantic Scholar
ClusterMine360: a database of microbial PKS/NRPS biosynthesis
Kyle R. Conway, C. Boddy
2012Nucleic Acids Res.126 citations Open access
Semantic Scholar
Total Synthesis of Vancomycin—Part 1: Design and Development of Methodology
K. Nicolaou, Hui Li, C. Boddy, J. Ramanjulu +5 more
1999124 citations
Semantic Scholar
Trapping biosynthetic acyl–enzyme intermediates with encoded 2,3-diaminopropionic acid
N. Huguenin-Dezot, D. Alonzo, Graham W. Heberlig, M. Mahesh +5 more
2018Nature109 citations Open access
Semantic Scholar
Total Synthesis of Vancomycin—Part 2: Retrosynthetic Analysis, Synthesis of Amino Acid Building Blocks and Strategy Evaluations
K. Nicolaou, C. Boddy, Hui Li, Alexandros E Koumbis +6 more
199997 citations
Semantic Scholar
New Synthetic Technology for the Synthesis of Aryl Ethers: Construction of C-O-D and D-O-E Ring Model Systems of Vancomycin
K. Nicolaou, C. Boddy, S. Natarajan, Tai-Yuen Yue +3 more
199797 citations
Semantic Scholar
Atropselective macrocyclization of diaryl ether ring systems: application to the synthesis of vancomycin model systems.
K. Nicolaou, C. Boddy
2002Journal of the American Chemical Society95 citations
Semantic Scholar
Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides
C. Boddy
2014Journal of Industrial Microbiology & Biotechnology76 citations Open access
Semantic Scholar
Understanding Substrate Specificity of Polyketide Synthase Modules by Generating Hybrid Multimodular Synthases*
Kenji Watanabe, Clay C. C. Wang, C. Boddy, D. Cane +1 more
2003Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Process Improvements for the Manufacture of Tenofovir Disoproxil Fumarate at Commercial Scale
D. H. Brown Ripin, David S. Teager, J. Fortunak, S. M. Basha +21 more
201061 citations
Semantic Scholar
Alternative Sigma Factor Over-Expression Enables Heterologous Expression of a Type II Polyketide Biosynthetic Pathway in Escherichia coli
D. C. Stevens, Kyle R. Conway, N. Pearce, L. R. Villegas-Peñaranda +2 more
2013PLoS ONE60 citations Open access
Semantic Scholar
Total Synthesis of Crystalline (.+-.)-Fredericamycin A. Use of Radical Spirocyclization
D. Clive, Y. Tao, A. Khodabocus, Yong-Jin Wu +5 more
199460 citations
Semantic Scholar
Land Use Intensity Controls Actinobacterial Community Structure
P. Hill, V. Krištůfek, L. Dijkhuizen, C. Boddy +2 more
2010Microbial Ecology57 citations Open access
Semantic Scholar
Precursor-directed biosynthesis of epothilone in Escherichia coli.
C. Boddy, K. Hotta, Martha Lovato Tse, R. E. Watts +1 more
2004Journal of the American Chemical Society54 citations
Semantic Scholar
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase.
C. Boddy, T. L. Schneider, K. Hotta, C. Walsh +1 more
2003Journal of the American Chemical Society54 citations
Semantic Scholar
Accessory Chromosome-Acquired Secondary Metabolism in Plant Pathogenic Fungi: The Evolution of Biotrophs Into Host-Specific Pathogens
T. Witte, N. Villeneuve, C. Boddy, D. Overy
2021Frontiers in Microbiology51 citations Open access
Semantic Scholar
Whole Genome Sequencing and Metabolomic Study of Cave Streptomyces Isolates ICC1 and ICC4
Jessica T Gosse, Soumya Ghosh, A. Sproule, D. Overy +2 more
2019Frontiers in Microbiology50 citations Open access
Semantic Scholar
Gene PA2449 Is Essential for Glycine Metabolism and Pyocyanin Biosynthesis in Pseudomonas aeruginosa PAO1
Benjamin R. Lundgren, W. Thornton, M. Dornan, L. R. Villegas-Peñaranda +2 more
2013Journal of Bacteriology50 citations Open access
Semantic Scholar
A thioesterase from an iterative fungal polyketide synthase shows macrocylization and cross-coupling activity, and may play a role in controlling iterative cycling through product off loading
Meng Wang, Hui Zhou, Monica Wirz, Yi Tang +1 more
2009Biochemistry48 citations Open access
Semantic Scholar
Sialic acid and N-acyl sialic acid analog production by fermentation of metabolically and genetically engineered Escherichia coli.
Benjamin R. Lundgren, C. Boddy
2007Organic and biomolecular chemistry47 citations
Semantic Scholar
Probing the Ring Size of Epothilones: Total Synthesis of [14]-, [15]-, [17]-, and [18]Epothilones A
K. C. Nicolaou, F. Sarabia, S. Ninkovic, M. Finlay +1 more
199845 citations
Semantic Scholar
6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective.
Atahualpa Pinto, Meng Wang, Mark E. Horsman, C. Boddy
2012Organic Letters44 citations
Semantic Scholar
A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis.
Wenjun Zhang, Burkhardt I. Wilke, J. Zhan, Kenji Watanabe +2 more
2007Journal of the American Chemical Society39 citations
Semantic Scholar
The thioesterase domain from the pimaricin and erythromycin biosynthetic pathways can catalyze hydrolysis of simple thioester substrates.
K. Sharma, C. Boddy
2007Bioorganic & Medicinal Chemistry Letters39 citations
Semantic Scholar
Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations.
Jeanette Young, D. C. Stevens, R. Carmichael, John C. Tan +4 more
2013Journal of Natural Products36 citations
Semantic Scholar
NEW TECHNOLOGY FOR THE SYNTHESIS OF VANCOMYCIN-TYPE BIARYL RING SYSTEMS
K. Nicolaou, Xin-jie Chu, J. Ramanjulu, S. Natarajan +3 more
199732 citations
Semantic Scholar
Genetic Analysis of the Assimilation of C5-Dicarboxylic Acids in Pseudomonas aeruginosa PAO1
Benjamin R. Lundgren, L. R. Villegas-Peñaranda, J. Harris, Alexander M Mottern +3 more
2014Journal of Bacteriology31 citations Open access
Semantic Scholar
Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue.
M. I. Hassan, Benjamin R. Lundgren, Michael Chaumun, D. Whitfield +3 more
2016Angewandte Chemie30 citations
Semantic Scholar
An Evolutionary Model Encompassing Substrate Specificity and Reactivity of Type I Polyketide Synthase Thioesterases
Taylor P. A. Hari, Puneet Labana, Meaghan Boileau, C. Boddy
2014ChemBioChem30 citations
Semantic Scholar
The role of transcription in heterologous expression of polyketides in bacterial hosts.
D. C. Stevens, Taylor P. A. Hari, C. Boddy
2013Natural product reports (Print)30 citations
Semantic Scholar
Examining the role of hydrogen bonding interactions in the substrate specificity for the loading step of polyketide synthase thioesterase domains.
M. Wang, C. Boddy
2008Biochemistry29 citations Open access
Semantic Scholar
First-in-class small molecule potentiators of cancer virotherapy
M. Dornan, Ramya Krishnan, A. Macklin, M. Selman +15 more
2016Scientific Reports28 citations Open access
Semantic Scholar
Resorcylic acid lactone biosynthesis relies on a stereotolerant macrocyclizing thioesterase.
G. Heberlig, Monica Wirz, Meng Wang, C. Boddy
2014Organic Letters28 citations
Semantic Scholar
Heterologous Expression of the Oxytetracycline Biosynthetic Pathway in Myxococcus xanthus
D. C. Stevens, Michael R. Henry, K. Murphy, C. Boddy
2010Applied and Environmental Microbiology27 citations Open access
Semantic Scholar
Apicidin biosynthesis is linked to accessory chromosomes in Fusarium poae isolates
T. Witte, L. Harris, H. Nguyen, A. Hermans +5 more
2020BMC Genomics25 citations Open access
Semantic Scholar
Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone
M. Wyatt, Yasodha Ahilan, P. Argyropoulos, C. Boddy +2 more
2013Journal of antibiotics (Tokyo. 1968)25 citations
Semantic Scholar
Total Synthesis of Vancomycin Aglycon-Part 1: Synthesis of Amino Acids 4-7 and Construction of the AB-COD Ring Skeleton.
K. Nicolaou, S. Natarajan, Hui Li, N. F. Jain +5 more
1998Angewandte Chemie24 citations
Semantic Scholar
Modulation of antifreeze activity and the effect upon post-thaw HepG2 cell viability after cryopreservation.
Chantelle J. Capicciotti, J. Poisson, C. Boddy, R. Ben
2015Cryobiology23 citations
Semantic Scholar
Rapid, mild method for phosphonate diester hydrolysis: development of a one-pot synthesis of tenofovir disoproxil fumarate from tenofovir diethyl ester
S. R. Houghton, J. Melton, J. Fortunak, D. H. Brown Ripin +1 more
201023 citations
Semantic Scholar
Biomineralization in Cave Bacteria—Popcorn and Soda Straw Crystal Formations, Morphologies, and Potential Metabolic Pathways
Keegan Koning, Richenda McFarlane, Jessica T Gosse, S. Lawrence +5 more
2022Frontiers in Microbiology19 citations Open access
Semantic Scholar
Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.
P. Argyropoulos, F. Bergeret, C. Pardin, J. Reimer +3 more
2016Biochimica et Biophysica Acta19 citations Open access
Semantic Scholar
Thioesterase from Cereulide Biosynthesis Is Responsible for Oligomerization and Macrocyclization of a Linear Tetradepsipeptide.
G. Heberlig, C. Boddy
2020Journal of Natural Products16 citations Open access
Semantic Scholar
Inhibition of Bacterial Gene Transcription with an RpoN-based Stapled Peptide
Sterling R. Payne, Daniel Pau, A. L. Whiting, Y. Kim +4 more
2018Cell Chemical Biology15 citations Open access
Semantic Scholar
CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm Fusarium graminearum C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones
C. Hicks, T. Witte, A. Sproule, A. Hermans +6 more
2023Journal of Fungi13 citations Open access
Semantic Scholar
Untargeted metabolomics screening reveals unique secondary metabolite production from Alternaria section Alternaria
T. Witte, N. Villenueve, Samuel W. J. Shields, A. Sproule +5 more
2022Frontiers in Molecular Biosciences13 citations Open access
Semantic Scholar
Thermoplasmonic ssDNA Dynamic Release from Gold Nanoparticles Examined with Advanced Fluorescence Microscopy.
S. Simoncelli, Hasitha de Alwis Weerasekera, Chiara Fasciani, C. Boddy +3 more
2015Journal of Physical Chemistry Letters13 citations Open access
Semantic Scholar

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