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E. Mezeiova · SciRah

Researcher profile · Semantic Scholar

E. Mezeiova

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E. Mezeiova — researcher profile on SciRah

h-index: 19
Works: 49
Citations: 941

Most-cited papers

Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
K. Chalupova, J. Korábečný, M. Bartolini, Barbara Monti +31 more
2019European journal of medicinal chemistry90 citations Open access
Semantic Scholar
Multitarget Tacrine Hybrids with Neuroprotective Properties to Confront Alzheimer's Disease.
K. Spilovska, J. Korábečný, E. Nepovimova, R. Doležal +3 more
2017Current Topics in Medicinal Chemistry74 citations
Semantic Scholar
Profiling donepezil template into multipotent hybrids with antioxidant properties
E. Mezeiova, K. Spilovska, E. Nepovimova, L. Górecki +7 more
2018Journal of Enzyme Inhibition and Medicinal Chemistry62 citations Open access
Semantic Scholar
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
Vendula Hepnarova, J. Korábečný, L. Matoušková, P. Jošt +15 more
2018European journal of medicinal chemistry59 citations Open access
Semantic Scholar
Newly Developed Drugs for Alzheimer's Disease in Relation to Energy Metabolism, Cholinergic and Monoaminergic Neurotransmission.
J. Korábečný, E. Nepovimova, Tereza Cikánková, K. Spilovska +4 more
2017Neuroscience54 citations
Semantic Scholar
Recent advances with 5-HT3 modulators for neuropsychiatric and gastrointestinal disorders.
Radomír Jůza, P. Vlček, E. Mezeiova, K. Musílek +2 more
2020Medicinal research reviews (Print)49 citations
Semantic Scholar
Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer’s Agents: Design, Synthesis and Biological Evaluation
K. Spilovska, J. Korábečný, V. Sepsova, D. Jun +10 more
2017Molecules44 citations Open access
Semantic Scholar
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer’s Disease Treatment
J. Korábečný, M. Andrs, E. Nepovimova, R. Doležal +10 more
2015Molecules44 citations Open access
Semantic Scholar
Orexin supplementation in narcolepsy treatment: A review
E. Nepovimova, J. Janockova, J. Misík, Š. Kubík +11 more
2018Medicinal research reviews (Print)37 citations
Semantic Scholar
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
K. Sobolová, M. Hrabinová, Vendula Hepnarova, T. Kučera +10 more
2020European journal of medicinal chemistry32 citations Open access
Semantic Scholar
Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders
Radomír Jůza, K. Musílek, E. Mezeiova, O. Soukup +1 more
2022Medicinal research reviews (Print)30 citations
Semantic Scholar
Donepezil Derivatives Targeting Amyloid-β cascade in Alzheimer's Disease.
E. Mezeiova, K. Chalupova, E. Nepovimova, L. Górecki +5 more
2019Current Alzheimer Research30 citations
Semantic Scholar
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
E. Mezeiova, J. Janockova, R. Andrýs, O. Soukup +13 more
2020European journal of medicinal chemistry29 citations Open access
Semantic Scholar
Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors
B. Svobodová, E. Mezeiova, Vendula Hepnarova, M. Hrabinová +7 more
2019Biomolecules29 citations Open access
Semantic Scholar
A systematic review on donepezil-based derivatives as potential cholinesterase inhibitors for Alzheimer's disease.
J. Korábečný, K. Spilovska, E. Mezeiova, O. Benek +3 more
2018Current Medicinal Chemistry29 citations
Semantic Scholar
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer’s Disease Therapy
E. Mezeiova, J. Korábečný, V. Sepsova, M. Hrabinová +13 more
2017Molecules28 citations Open access
Semantic Scholar
Total synthesis of (−)-jaspine B and its 4-epi-analogue from d-xylose
M. Martinková, E. Mezeiova, J. Gonda, Dominika Jacková +1 more
201424 citations
Semantic Scholar
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.
L. Górecki, Elisa Uliassi, M. Bartolini, J. Janockova +14 more
2021ACS Chemical Neuroscience23 citations Open access
Semantic Scholar
Total synthesis of pachastrissamine together with its 4-epi-congener via [3,3]-sigmatropic rearrangements and antiproliferative/cytotoxic evaluation.
M. Martinková, E. Mezeiova, Milica Fabišíková, J. Gonda +2 more
2015Carbohydrate Research20 citations
Semantic Scholar
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
D. Maliňák, R. Doležal, Vendula Hepnarova, Miroslava Hozova +10 more
2020Journal of Enzyme Inhibition and Medicinal Chemistry19 citations Open access
Semantic Scholar
Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.
Anna Pasieka, Dawid Panek, Jakub Jończyk, Justyna Godyń +16 more
2021European journal of medicinal chemistry18 citations Open access
Semantic Scholar
A Review of the Synthesis of Quaternary Acetylcholinesterase Reactivators
D. Maliňák, J. Korábečný, O. Soukup, L. Górecki +7 more
2018Current organic chemistry14 citations
Semantic Scholar
Morphing Cholinesterase Inhibitor Amiridine into Multipotent Drugs for the Treatment of Alzheimer’s Disease
E. Mezeiova, L. Prchal, M. Hrabinová, Ľ. Múčková +9 more
2024bioRxiv13 citations Open access
Semantic Scholar
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.
Vladimir Finger, T. Kučera, Radka Kafková, Ľ. Múčková +22 more
2023European journal of medicinal chemistry13 citations Open access
Semantic Scholar
Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods
J. Janockova, R. Doležal, E. Nepovimova, T. Kobrlova +9 more
2018Molecules10 citations Open access
Semantic Scholar
Total synthesis and antiproliferative/cytotoxic profiling of 2-epi-jaspine B.
E. Mezeiova, M. Martinková, K. Stanková, Milica Fabišíková +3 more
2016Carbohydrate Research10 citations
Semantic Scholar
Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.
Radomír Jůza, I. Vojtěchová, Kristýna Štefková-Mazochová, W. Dehaen +18 more
2022European journal of medicinal chemistry9 citations Open access
Semantic Scholar
Huprine Y - tryptophan heterodimers with potential implication to Alzheimer's disease treatment.
E. Mezeiova, M. Hrabinová, Vendula Hepnarova, D. Jun +11 more
2021Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats.
J. Zdarova-Karasova, V. Šesták, J. Korábečný, E. Mezeiova +3 more
2018Journal of chromatography. B, Analytical technologies in the biomedical and life sciences8 citations
Semantic Scholar
Jaspine B Hydrochloride-induced Apoptosis in HeLa Cells Is Associated With Disrupted Sphingolipid Metabolism and Ceramide Overload
A. Bogdanova, M. Kello, A. Macejova, Natália Nosálová +7 more
2021Anticancer Research7 citations Open access
Semantic Scholar
From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia.
E. Mezeiova, J. Janockova, J. Konečný, T. Kobrlova +6 more
2020Bioorganic chemistry (Print)7 citations
Semantic Scholar
Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides.
Vendula Hepnarova, M. Hrabinová, Ľ. Múčková, T. Kučera +8 more
2022Toxicology in Vitro6 citations
Semantic Scholar
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole
Radomír Jůza, K. Štefková, W. Dehaen, Alena Randáková +11 more
2021Biomolecules6 citations Open access
Semantic Scholar
Huprines — an insight into the synthesis and biological properties
E. Mezeiova, O. Soukup, J. Korábečný
2020Russian Chemical Reviews3 citations Open access
Semantic Scholar
Effect of hexyloxy position on antagonistic properties of KH-5 (1-{2-[4-(hexyloxy)benzoyloxy]ethyl}-1-methyl-1,2,3,6-tetrahydropyridin-1-ium iodide) at muscarinic acetylcholine receptors.
Alena Janoušková-Randáková, E. Mezeiova, Jana Bláhová, N. Chetverikov +6 more
2025Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie1 citations Open access
Semantic Scholar
In vitro effects of newly developed cholinesterase inhibitors and ABAD modulators on mitochondrial respiration
J. Hroudová, Z. Fišar, J. Korábečný, E. Nepovimova +6 more
20171 citations
Semantic Scholar
Total Synthesis of (‐)‐Jaspine B (I) and Its 4‐epi‐Analogue (II) from D‐Xylose.
M. Martinková, E. Mezeiova, J. Gonda, Dominika Jacková +1 more
20141 citations
Semantic Scholar
Balancing Rigidity and Flexibility: Optimised 4-(Hexyloxy)benzoate Antagonists with Enhanced Affinity and Tuneable Duration at Muscarinic Receptors
Eva Dolejší, E. Mezeiova, Jana Bláhová, N. Chetverikov +7 more
2025bioRxiv0 citations Open access
Semantic Scholar
DESIGN, CHEMICAL SYNTHESIS, AND IN VITRO EVALUATION OF NOVEL UNCHARGED CHOLINESTERASE REACTIVATOR
Vendula Hepnarova, M. Hrabinová, Jakub Opravil, M. Vaněk +7 more
2024Military Medical Science Letters0 citations Open access
Semantic Scholar
UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data.
M. Mžik, V. Šesták, E. Mezeiova, J. Korábečný +3 more
2022Journal of Pharmaceutical and Biomedical Analysis0 citations
Semantic Scholar
NEUROPROTECTIVE EFFECT OF GALANTAMINE AGAINST EXPERIMENTALLY INDUCED OXIDATIVE STRESS IN IMR 32 CELLS
Sharma Rk, Shagun Dubey, Nj, A. Farr +64 more
2021International Journal of Biology Pharmacy and Allied Sciences0 citations Open access
Semantic Scholar
Review of Synthetic Approaches to Dizocilpine
J. Konečný, E. Mezeiova, O. Soukup, J. Korábečný
20210 citations
Semantic Scholar
Inside Front Cover Image, Volume 40, Issue 5
Radomír Jůza, P. Vlček, E. Mezeiova, K. Musílek +2 more
2020Medicinal research reviews (Print)0 citations
Semantic Scholar
P.760 Effects of novel cholinesterase inhibitors on mitochondrial respiration and MAO activity - in vitro study
J. Hroudová, J. Korábečný, K. Spilovska, E. Mezeiova +3 more
2020European Neuropsychopharmacology0 citations
Semantic Scholar
Non-peptide orexin 2 receptor modulators as promising way to treatment of narcolepsy/insomnia
J. Janockova, Tereza Kobrlova, E. Mezeiova, R. Doležal +2 more
2019Journal of Neurological Sciences0 citations
Semantic Scholar
DISCOVERY AND CHARACTERIZATION OF TACRINE/HUPRINE-TRYPTOPHAN HETERODIMERS AS NOVEL MULTIPOTENT COMPOUNDS AGAINST ALZHEIMER'S DISEASE
J. Korábečný, K. Spilovska, M. Bartolini, Barbara Monti +13 more
20180 citations
Semantic Scholar
7-MEOTA-DONEPEZIL HYBRIDS: POTENTIAL CHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER’S DISEASE
K. Spilovska, E. Mezeiova, J. Korábečný, J. Hroudová +6 more
20180 citations
Semantic Scholar
Alzheimer’s Disease Drugs- In Vitro Comparison of Cholinesterase Inhibition and beta-amyloid Modulation
O. Holas, J. Korábečný, Z. Gažová, K. Siposova +7 more
20170 citations
Semantic Scholar
Interný audit manažérskych procesov vybraného podniku
E. Mezeiova
20140 citations
Semantic Scholar

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J. Korábečný×43
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O. Soukup×32
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K. Kuča×19
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Vendula Hepnarova×12

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