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T. Joensuu · SciRah

Researcher profile · Semantic Scholar

T. Joensuu

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T. Joensuu — researcher profile on SciRah

h-index: 38
Works: 117
Citations: 6,725

Most-cited papers

Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF.
A. Koski, L. Kangasniemi, S. Escutenaire, S. Pesonen +21 more
2010Molecular Therapy262 citations Open access
Semantic Scholar
Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients.
V. Cerullo, S. Pesonen, I. Diaconu, S. Escutenaire +22 more
2010Cancer Research241 citations Open access
Semantic Scholar
2-Weekly versus 3-weekly docetaxel to treat castration-resistant advanced prostate cancer: a randomised, phase 3 trial.
P. Kellokumpu-Lehtinen, U. Harmenberg, T. Joensuu, R. Mcdermott +16 more
2013The Lancet Oncology207 citations
Semantic Scholar
Phase I study with ONCOS-102 for the treatment of solid tumors – an evaluation of clinical response and exploratory analyses of immune markers
T. Ranki, S. Pesonen, A. Hemminki, K. Partanen +22 more
2016Journal of Immunotherapy for Cancer200 citations Open access
Semantic Scholar
Third-line treatment and 177Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review
F. V. von Eyben, G. Roviello, T. Kiljunen, C. Uprimny +3 more
2017European Journal of Nuclear Medicine and Molecular Imaging176 citations Open access
Semantic Scholar
Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
A. Kanerva, Petri Nokisalmi, I. Diaconu, A. Koski +14 more
2013Clinical Cancer Research172 citations Open access
Semantic Scholar
Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients.
Ilkka Liikanen, L. Ahtiainen, M. Hirvinen, Simona Bramante +15 more
2013Molecular Therapy170 citations Open access
Semantic Scholar
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus.
V. Cerullo, I. Diaconu, L. Kangasniemi, Maria Rajecki +17 more
2011Molecular Therapy169 citations Open access
Semantic Scholar
Oncolytic Adenovirus ICOVIR-7 in Patients with Advanced and Refractory Solid Tumors
Petri Nokisalmi, S. Pesonen, S. Escutenaire, M. Sarkioja +17 more
2010Clinical Cancer Research124 citations Open access
Semantic Scholar
Integrin targeted oncolytic adenoviruses Ad5‐D24‐RGD and Ad5‐RGD‐D24‐GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors
S. Pesonen, I. Diaconu, V. Cerullo, S. Escutenaire +17 more
2012International Journal of Cancer104 citations Open access
Semantic Scholar
Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy
O. Hemminki, S. Parviainen, J. Juhila, Riku Turkki +13 more
2015OncoTarget91 citations Open access
Semantic Scholar
Randomised Trial of Adjuvant Radiotherapy Following Radical Prostatectomy Versus Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension.
G. Hackman, K. Taari, T. Tammela, M. Matikainen +17 more
2019European Urology88 citations
Semantic Scholar
Ad3-hTERT-E1A, a fully serotype 3 oncolytic adenovirus, in patients with chemotherapy refractory cancer.
O. Hemminki, I. Diaconu, V. Cerullo, S. Pesonen +9 more
2012Molecular Therapy87 citations Open access
Semantic Scholar
A Deep Learning-Based Automated CT Segmentation of Prostate Cancer Anatomy for Radiation Therapy Planning-A Retrospective Multicenter Study
T. Kiljunen, S. Akram, J. Niemelä, E. Löyttyniemi +22 more
2020Diagnostics73 citations Open access
Semantic Scholar
Radiotherapy Boost for the Dominant Intraprostatic Cancer Lesion-A Systematic Review and Meta-Analysis.
F. V. von Eyben, T. Kiljunen, A. Kangasmaki, K. Kairemo +2 more
2016Clinical Genitourinary Cancer66 citations
Semantic Scholar
Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8+ T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer
L. Vassilev, T. Ranki, T. Joensuu, E. Jäger +21 more
2015Oncoimmunology60 citations Open access
Semantic Scholar
Serum HMGB1 is a predictive and prognostic biomarker for oncolytic immunotherapy
Ilkka Liikanen, A. Koski, Maiju Merisalo-Soikkeli, O. Hemminki +5 more
2015Oncoimmunology58 citations Open access
Semantic Scholar
Preliminary Clinical Experience of trans-1-Amino-3-(18)F-fluorocyclobutanecarboxylic Acid (anti-(18)F-FACBC) PET/CT Imaging in Prostate Cancer Patients
K. Kairemo, N. Rasulova, K. Partanen, T. Joensuu
2014BioMed Research International55 citations Open access
Semantic Scholar
Treatment of melanoma with a serotype 5/3 chimeric oncolytic adenovirus coding for GM‐CSF: Results in vitro, in rodents and in humans
Simona Bramante, Johanna K. Kaufmann, V. Veckman, Ilkka Liikanen +13 more
2015International Journal of Cancer50 citations
Semantic Scholar
Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8+ T-cell response, prominent infiltration of CD8+ lymphocytes and Th1 type polarization
T. Ranki, T. Joensuu, E. Jäger, J. Karbach +21 more
2014Oncoimmunology50 citations Open access
Semantic Scholar
Radium-223-Dichloride in Castration Resistant Metastatic Prostate Cancer—Preliminary Results of the Response Evaluation Using F-18-Fluoride PET/CT
K. Kairemo, T. Joensuu
2015Diagnostics47 citations Open access
Semantic Scholar
Serotype chimeric oncolytic adenovirus coding for GM‐CSF for treatment of sarcoma in rodents and humans
Simona Bramante, A. Koski, A. Kipar, I. Diaconu +15 more
2014International Journal of Cancer44 citations Open access
Semantic Scholar
Switching the fiber knob of oncolytic adenoviruses to avoid neutralizing antibodies in human cancer patients
M. Raki, M. Sarkioja, S. Escutenaire, L. Kangasniemi +7 more
2011Journal of Gene Medicine43 citations
Semantic Scholar
Verapamil results in increased blood levels of oncolytic adenovirus in treatment of patients with advanced cancer.
A. Koski, M. Raki, Petri Nokisalmi, Ilkka Liikanen +6 more
2012Molecular Therapy42 citations Open access
Semantic Scholar
177Lu-PSMA radioligand therapy of predominant lymph node metastatic prostate cancer
F. V. von Eyben, Aviral Singh, Jingjing Zhang, K. Nipsch +8 more
2019OncoTarget41 citations Open access
Semantic Scholar
Oncolytic adenovirus treatment of a patient with refractory neuroblastoma
S. Pesonen, H. Helin, Petri Nokisalmi, S. Escutenaire +14 more
2010Acta oncologica40 citations Open access
Semantic Scholar
Impact of preoperative chemoradiotherapy on survival in patients with resectable pancreatic cancer.
P. Vento, H. Mustonen, T. Joensuu, P. Kärkkäinen +2 more
2007World Journal of Gastroenterology40 citations Open access
Semantic Scholar
Trabectedin in the treatment of metastatic soft tissue sarcoma: cost-effectiveness, cost-utility and value of information
E. Soini, B. D. Andrés, T. Joensuu
2010Annals of Oncology38 citations Open access
Semantic Scholar
Oncolytic virotherapy for treatment of breast cancer, including triple-negative breast cancer
Simona Bramante, A. Koski, Ilkka Liikanen, L. Vassilev +8 more
2016Oncoimmunology36 citations Open access
Semantic Scholar
Predictive and Prognostic Clinical Variables in Cancer Patients Treated With Adenoviral Oncolytic Immunotherapy.
Kristian Taipale, Ilkka Liikanen, A. Koski, Raita Heiskanen +7 more
2016Molecular Therapy36 citations Open access
Semantic Scholar
Oral tongue carcinoma and its treatment in Finland
A. Mäkitie, P. Koivunen, H. Keski-Säntti, J. Törnwall +7 more
2007European Archives of Oto-Rhino-Laryngology34 citations
Semantic Scholar
Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus.
Kristian Taipale, Ilkka Liikanen, J. Juhila, Riku Turkki +14 more
2016Molecular Therapy32 citations Open access
Semantic Scholar
Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues.
A. Koski, Simona Bramante, A. Kipar, M. Oksanen +5 more
2015Molecular Therapy31 citations Open access
Semantic Scholar
[(18)F]-fluorodeoxyglucose positron emission tomography and computed tomography in response evaluation of oncolytic adenovirus treatments of patients with advanced cancer.
A. Koski, Helena Ahtinen, H. Liljenbäck, A. Roivainen +7 more
2013Human Gene Therapy28 citations
Semantic Scholar
A phase I/II trial of gefitinib given concurrently with radiotherapy in patients with nonmetastatic prostate cancer.
Greetta Joensuu, T. Joensuu, Petri Nokisalmi, C. Reddy +7 more
2010International Journal of Radiation Oncology, Biology, Physics28 citations
Semantic Scholar
Biweekly docetaxel is better tolerated than conventional three-weekly dosing for advanced hormone-refractory prostate cancer.
P. Hervonen, H. Joensuu, T. Joensuu, Ginman Claes +11 more
2012Anticancer Research26 citations
Semantic Scholar
In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments
S. Escutenaire, V. Cerullo, I. Diaconu, L. Ahtiainen +13 more
2011Annals medicus25 citations Open access
Semantic Scholar
Sodium iodide symporter SPECT imaging of a patient treated with oncolytic adenovirus Ad5/3-Δ24-hNIS.
Maria Rajecki, A. Kangasmäki, L. Laasonen, S. Escutenaire +9 more
2011Molecular Therapy22 citations Open access
Semantic Scholar
Oncolytic adenovirus decreases the proportion of TIM-3+ subset of tumor-infiltrating CD8+ T cells with correlation to improved survival in patients with cancer
Ilkka Liikanen, S. Basnet, D. Quixabeira, Kristian Taipale +8 more
2022Journal for ImmunoTherapy of Cancer19 citations Open access
Semantic Scholar
Case-control estimation of the impact of oncolytic adenovirus on the survival of patients with refractory solid tumors.
A. Kanerva, A. Koski, Ilkka Liikanen, M. Oksanen +5 more
2015Molecular Therapy19 citations Open access
Semantic Scholar
The clinical impact of using complex molecular profiling strategies in routine oncology practice
J. Laes, P. Aftimos, P. Barthélémy, J. Bellmunt +27 more
2018OncoTarget18 citations Open access
Semantic Scholar
In vivo magnetic resonance imaging and spectroscopy identifies oncolytic adenovirus responders
O. Hemminki, R. Immonen, J. Närväinen, A. Kipar +14 more
2014International Journal of Cancer18 citations Open access
Semantic Scholar
Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment
M. Hirvinen, Raita Heiskanen, M. Oksanen, S. Pesonen +5 more
2013Journal of Translational Medicine18 citations Open access
Semantic Scholar
Planning of External Beam Radiotherapy for Prostate Cancer Guided by PET/CT.
F. V. von Eyben, K. Kairemo, T. Kiljunen, T. Joensuu
2015Current Radiopharmaceuticals17 citations
Semantic Scholar
Interleukin 8 activity influences the efficacy of adenoviral oncolytic immunotherapy in cancer patients
Kristian Taipale, S. Tähtinen, R. Havunen, A. Koski +7 more
2018OncoTarget16 citations Open access
Semantic Scholar
177Lu-PSMA-617 radioligand therapy for a patient with lymph node metastatic prostate cancer
F. V. von Eyben, T. Kiljunen, T. Joensuu, K. Kairemo +2 more
2017OncoTarget16 citations Open access
Semantic Scholar
Evaluation of Alpha-Therapy with Radium-223-Dichloride in Castration Resistant Metastatic Prostate Cancer—the Role of Gamma Scintigraphy in Dosimetry and Pharmacokinetics
K. Kairemo, T. Joensuu, N. Rasulova, T. Kiljunen +1 more
2015Diagnostics14 citations Open access
Semantic Scholar
Phase II prospective trial of gefitinib given concurrently with cisplatin and radiotherapy in patients with locally advanced head and neck cancer.
K. Saarilahti, P. Bono, M. Kajanti, L. Bäck +4 more
2010The Journal of Otolaryngology14 citations
Semantic Scholar
Accuracy and precision of patient positioning for pelvic MR-only radiation therapy using digitally reconstructed radiographs
R. Kemppainen, T. Vaara, T. Joensuu, T. Kiljunen
2018Physics in Medicine and Biology13 citations Open access
Semantic Scholar
VMAT technique enables concomitant radiotherapy of prostate cancer and pelvic bone metastases
T. Kiljunen, A. Kangasmäki, A. Aaltonen, K. Kairemo +5 more
2015Acta oncologica13 citations Open access
Semantic Scholar

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A. Kanerva×24
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A. Koski — researcher profile on SciRah

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