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L. C̆ervenka · SciRah

Researcher profile · Semantic Scholar

L. C̆ervenka

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L. C̆ervenka — researcher profile on SciRah

h-index: 37
Works: 192
Citations: 3,759

Most-cited papers

Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension
J. Neckář, L. Kopkan, Z. Husková, F. Kolář +9 more
2012Clinical science69 citations Open access
Semantic Scholar
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
V. Hampl, J. Herget, J. Bíbová, A. Baňasová +7 more
2015Physiological Research59 citations Open access
Semantic Scholar
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren‐2 transgenic hypertensive rats with aorto‐caval fistula
L. C̆ervenka, V. Melenovský, Z. Husková, P. Škaroupková +2 more
2015Clinical and Experimental Pharmacology and Physiology45 citations
Semantic Scholar
Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
P. Kujal, V. Chábová, P. Škaroupková, Z. Husková +11 more
2014Clinical and Experimental Pharmacology and Physiology40 citations Open access
Semantic Scholar
Right versus left ventricular remodeling in heart failure due to chronic volume overload
T. Havlenova, P. Škaroupková, M. Miklovič, M. Běhounek +10 more
2021Scientific Reports35 citations Open access
Semantic Scholar
Kidney Response to Heart Failure: Proteomic Analysis of Cardiorenal Syndrome
V. Melenovský, L. C̆ervenka, O. Viklicky, J. Franeková +4 more
2018Kidney & Blood Pressure Research35 citations Open access
Semantic Scholar
Intrarenal alterations of the angiotensin‐converting enzyme type 2/angiotensin 1–7 complex of the renin‐angiotensin system do not alter the course of malignant hypertension in Cyp1a1‐Ren‐2 transgenic rats
Z. Husková, L. Kopkan, L. Červenková, Š. Doleželová +7 more
2016Clinical and Experimental Pharmacology and Physiology33 citations
Semantic Scholar
High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity
A. Walkowska, M. Kuczeriszka, J. Sadowski, K. Olszynski +4 more
2015Kidney & Blood Pressure Research30 citations Open access
Semantic Scholar
Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula
L. C̆ervenka, V. Melenovský, Z. Husková, A. Sporková +6 more
2015Physiological Research29 citations Open access
Semantic Scholar
Tacrolimus-induced hypertension and nephrotoxicity in Fawn-Hooded rats are attenuated by dual inhibition of renin–angiotensin system
L. Hošková, I. Málek, J. Kautzner, E. Honsova +6 more
2014Hypertension Research29 citations Open access
Semantic Scholar
Addition of ET(A) receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats.
V. Čertíková Chábová, Z. Vernerová, P. Kujal, Z. Husková +8 more
2014Life Science27 citations Open access
Semantic Scholar
Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension
L. C̆ervenka, Z. Husková, L. Kopkan, S. Kikerlová +11 more
2018Journal of Hypertension26 citations Open access
Semantic Scholar
Myocardial iron homeostasis and hepcidin expression in a rat model of heart failure at different levels of dietary iron intake.
J. Petrák, T. Havlenova, M. Krijt, M. Běhounek +5 more
2019Biochimica et Biophysica Acta - General Subjects25 citations Open access
Semantic Scholar
Different mechanisms of acute versus long term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats
A. Sporková, Šárka Jíchová, Z. Husková, L. Kopkan +8 more
2014Clinical and Experimental Pharmacology and Physiology23 citations Open access
Semantic Scholar
Soluble guanylyl cyclase stimulators and activators: promising drugs for the treatment of hypertension?
O. Gawryś, P. Kala, J. Sadowski, V. Melenovský +2 more
2024European Journal of Pharmacology22 citations Open access
Semantic Scholar
Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation
P. Kala, M. Miklovič, Šárka Jíchová, P. Škaroupková +13 more
2021Biomedicines22 citations Open access
Semantic Scholar
Epoxylipids and Soluble Epoxide Hydrolase in Heart Diseases
J. Imig, L. C̆ervenka, J. Neckář
2021Biochemical Pharmacology22 citations Open access
Semantic Scholar
Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME
Zuzana Honetschlägerová, Kento Kitada, Z. Husková, A. Sporková +11 more
2013Journal of Hypertension22 citations Open access
Semantic Scholar
Effect of angiotensin-converting enzyme blockade alone or combined with blockade of soluble epoxide hydrolase on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula
P. Kala, L. Sedláková, P. Škaroupková, L. Kopkan +9 more
2018Physiological Research21 citations Open access
Semantic Scholar
Selective replacement of mitochondrial DNA increases the cardioprotective effect of chronic continuous hypoxia in spontaneously hypertensive rats.
J. Neckář, Anna Svatoňová, Romana Weissova, Z. Drahota +17 more
2017Clinical science21 citations
Semantic Scholar
Renin–angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
L. Sedláková, Věra Čertíková Chábová, Š. Doleželová, P. Škaroupková +10 more
2017Clinical and experimental hypertension21 citations
Semantic Scholar
Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats
Šárka Jíchová, L. Kopkan, Z. Husková, Š. Doleželová +10 more
2016Journal of Hypertension21 citations Open access
Semantic Scholar
Fenofibrate Attenuates Malignant Hypertension by Suppression of the Renin‐angiotensin System: A Study in Cyp1a1‐Ren‐2 Transgenic Rats
Šárka Jíchová, Š. Doleželová, L. Kopkan, E. Kompanowska-Jezierska +2 more
2016American Journal of the Medical Sciences20 citations
Semantic Scholar
The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula
O. Gawryś, Z. Husková, P. Škaroupková, Z. Honetschlagerová +7 more
2023Naunyn-Schmiedeberg's Archives of Pharmacology19 citations Open access
Semantic Scholar
Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure
Šárka Vacková, S. Kikerlová, V. Melenovský, F. Kolář +4 more
2019Kidney & Blood Pressure Research19 citations Open access
Semantic Scholar
Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system
Šárka Varcabová, Z. Husková, Herbert J. Kramer, S. H. Hwang +4 more
2013Clinical and Experimental Pharmacology and Physiology19 citations Open access
Semantic Scholar
Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat
P. Kala, Hana Bartuskova, J. Piťha, Z. Vaňourková +10 more
2020International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats
J. Hrdlička, J. Neckář, F. Papoušek, Z. Husková +11 more
2019Frontiers in Pharmacology18 citations Open access
Semantic Scholar
Renoprotective effects of ET(A) receptor antagonists therapy in experimental non-diabetic chronic kidney disease: Is there still hope for the future?
I. Vaněčková, S. Hojná, M. Kadlecová, Z. Vernerová +3 more
2018Physiological Research18 citations Open access
Semantic Scholar
Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension
P. Kala, O. Gawryś, M. Miklovič, Z. Vaňourková +10 more
2022Journal of Hypertension17 citations Open access
Semantic Scholar
The Role of Renal Vascular Reactivity in the Development of Renal Dysfunction in Compensated and Decompensated Congestive Heart Failure
V. Kratky, L. Kopkan, S. Kikerlová, Z. Husková +4 more
2018Kidney & Blood Pressure Research17 citations Open access
Semantic Scholar
20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats
L. Sedláková, S. Kikerlová, Z. Husková, L. Červenková +9 more
2018Bioscience Reports17 citations Open access
Semantic Scholar
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
L. C̆ervenka, J. Bíbová, Z. Husková, Z. Vaňourková +5 more
2015Physiological Research17 citations Open access
Semantic Scholar
Effects of renal sympathetic denervation on the course of congestive heart failure combined with chronic kidney disease: Insight from studies with fawn-hooded hypertensive rats with volume overload induced using aorto-caval fistula
Z. Honetschlagerová, P. Škaroupková, S. Kikerlová, Z. Husková +8 more
2021Clinical and experimental hypertension16 citations Open access
Semantic Scholar
Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
P. Alánová, Z. Husková, L. Kopkan, A. Sporková +15 more
2015Vascular pharmacology16 citations
Semantic Scholar
Progression of hypertension and kidney disease in aging fawn-hooded rats is mediated by enhanced influence of renin–angiotensin system and suppression of nitric oxide system and epoxyeicosanoids
Š. Doleželová, Šárka Jíchová, Z. Husková, Alžběta Vojtíšková +6 more
2016Clinical and experimental hypertension15 citations Open access
Semantic Scholar
Sex‐linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren‐2 transgenic hypertensive rats with volume overload induced using aorto‐caval fistula
L. C̆ervenka, P. Škaroupková, E. Kompanowska-Jezierska, J. Sadowski
2016Clinical and Experimental Pharmacology and Physiology15 citations
Semantic Scholar
Ventricular assist devices in heart failure: how to support the heart but prevent atrophy?
M. Pokorný, L. C̆ervenka, I. Netuka, J. Pirk +2 more
2014Physiological Research15 citations Open access
Semantic Scholar
Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats.
O. Gawryś, Z. Husková, I. Baranowska, A. Walkowska +9 more
2020Journal of Hypertension14 citations
Semantic Scholar
The dilemma of dual renin-angiotensin system blockade in chronic kidney disease: why beneficial in animal experiments but not in the clinic?
V. Chábová, L. C̆ervenka
2017Physiological Research14 citations Open access
Semantic Scholar
Effects of Angiotensin II AT1–Receptor Blockade on High Fat Diet–Induced Vascular Oxidative Stress and Endothelial Dysfunction in Dahl Salt-Sensitive Rats
Shinji Kosaka, Nicolas Pelisch, Matlubur Rahman, D. Nakano +10 more
2013Journal of Pharmacological Sciences14 citations Open access
Semantic Scholar
Endothelin type A receptor blockade increases renoprotection in congestive heart failure combined with chronic kidney disease: Studies in 5/6 nephrectomized rats with aorto-caval fistula.
P. Kala, Z. Vaňourková, P. Škaroupková, E. Kompanowska-Jezierska +7 more
2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie13 citations Open access
Semantic Scholar
Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats
Šárka Vacková, L. Kopkan, S. Kikerlová, Z. Husková +7 more
2019Frontiers in Pharmacology13 citations Open access
Semantic Scholar
Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease
V. Chábová, P. Kujal, P. Škaroupková, Zdeňka Varňourková +11 more
2018Kidney & Blood Pressure Research13 citations Open access
Semantic Scholar
Sex-linked differences in the mortality in Ren-2 transgenic hypertensive rats with aorto-caval fistula: effects of treatment with angiotensin converting enzyme alone and combined with inhibitor of soluble epoxide hydrolase.
P. Kala, L. C̆ervenka, P. Škaroupková, M. Táborský +2 more
2019Physiological Research12 citations Open access
Semantic Scholar
Fenofibrate Attenuates Hypertension in Goldblatt Hypertensive Rats: Role of 20‐Hydroxyeicosatetraenoic Acid in the Nonclipped Kidney
A. Sporková, V. Chábová, Š. Doleželová, Šárka Jíchová +6 more
2017American Journal of the Medical Sciences12 citations
Semantic Scholar
Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure.
A. Sporková, Z. Husková, P. Škaroupková, N. R. Reddy +3 more
2017Physiological Research11 citations Open access
Semantic Scholar
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula
Z. Honetschlagerová, O. Gawryś, Šárka Jíchová, P. Škaroupková +11 more
2021Kidney & Blood Pressure Research10 citations Open access
Semantic Scholar
Isovolumic loading of the failing heart by intraventricular placement of a spring expander attenuates cardiac atrophy after heterotopic heart transplantation
M. Pokorný, I. Mrázová, Jan Šochman, V. Melenovský +10 more
2018Bioscience Reports10 citations Open access
Semantic Scholar
Renal sympathetic denervation improves pressure-natriuresis relationship in cardiorenal syndrome: insight from studies with Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula
Z. Honetschlagerová, Z. Husková, S. Kikerlová, J. Sadowski +5 more
2024Hypertension Research9 citations Open access
Semantic Scholar

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