J. Raper

Most-cited papers

Evolution of the primate trypanolytic factor APOL1
Russell Thomson, G. Genovese, C. Canon, Daniella Kovacsics +12 more
2014Proceedings of the National Academy of Sciences of the United States of America229 citations Open access
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Characterization of a Novel Trypanosome Lytic Factor from Human Serum
J. Raper, Ramie Fung, J. Ghiso, V. Nussenzweig +1 more
1999Infection and Immunity165 citations Open access
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Fatty acid remodeling: a novel reaction sequence in the biosynthesis of trypanosome glycosyl phosphatidylinositol membrane anchors.
W. J. Masterson, J. Raper, T. Doering, G. Hart +1 more
1990Cell157 citations Open access
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Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model
Maria del Pilar Molina-Portela, Marie Samanovic, J. Raper
2008Journal of Experimental Medicine102 citations Open access
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Trypanosome Lytic Factor, an Antimicrobial High-Density Lipoprotein, Ameliorates Leishmania Infection
Marie Samanovic, Maria del Pilar Molina-Portela, Anne-Danielle C. Chessler, B. Burleigh +1 more
2009PLoS Pathogens92 citations Open access
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Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening
Esther Bettiol, Marie Samanovic, A. S. Murkin, J. Raper +2 more
2009PLoS Neglected Tropical Diseases88 citations Open access
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Trypanosome lytic factor, a subclass of high-density lipoprotein, forms cation-selective pores in membranes.
Maria del Pilar Molina-Portela, E. Lugli, E. Recio-Pinto, J. Raper
2005Molecular and biochemical parasitology (Print)87 citations
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Characterization of primate trypanosome lytic factors.
E. Lugli, M. Pouliot, Maria del Pilar Molina Portela, M. Loomis +1 more
2004Molecular and biochemical parasitology (Print)86 citations
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Structure of the trypanosome haptoglobin–hemoglobin receptor and implications for nutrient uptake and innate immunity
M. Higgins, O. Tkachenko, Alan Brown, J. Reed +2 more
2013Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
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Evidence for a Trypanosoma brucei Lipoprotein Scavenger Receptor*
Heather P Green, Maria Del Pilar Molina Portela, Emmanuelle N. St Jean, E. Lugli +1 more
2003Journal of Biological Chemistry78 citations Open access
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Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes
Russell Thomson, Pilar Molina-Portela, H. Mott, M. Carrington +1 more
2009Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
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Trypanosome lytic factors: novel mediators of human innate immunity.
J. Raper, M. P. Portela, E. Lugli, U. Frevert +1 more
2001Current Opinion in Microbiology72 citations
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The main lytic factor of Trypanosoma brucei brucei in normal human serum is not high density lipoprotein
J. Raper, V. Nussenzweig, S. Tomlinson
1996Journal of Experimental Medicine72 citations Open access
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An analog of myristic acid with selective toxicity for African trypanosomes.
T. Doering, J. Raper, L. Buxbaum, S. Adams +3 more
1991Science72 citations
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Early Invasion of Brain Parenchyma by African Trypanosomes
U. Frevert, A. Movila, O. Nikolskaia, J. Raper +4 more
2012PLoS ONE67 citations Open access
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Natural human immunity to trypanosomes.
S. Tomlinson, J. Raper
1998Parasitology Today60 citations Open access
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African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat
Jason Pinger, D. Nešić, Liaqat Ali, Francisco Aresta-Branco +8 more
2018Nature Microbiology59 citations Open access
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Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity
J. Giovinazzo, Russell Thomson, Nailya Khalizova, Patrick J. Zager +4 more
2020eLife57 citations Open access
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Differences between Trypanosoma brucei gambiense Groups 1 and 2 in Their Resistance to Killing by Trypanolytic Factor 1
P. Capewell, Nicola J. Veitch, C. Turner, J. Raper +3 more
2011PLoS Neglected Tropical Diseases50 citations Open access
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BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins.
J. Heneghan, D. Vandorpe, B. Shmukler, J. Giovinazzo +4 more
2015American Journal of Physiology - Cell Physiology45 citations Open access
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Identification of Complete Precursors for the Glycosylphosphatidylinositol Protein Anchors of Trypanosoma cruzi*
Norton Heise, J. Raper, L. Buxbaum, T. M. Peranovich +1 more
1996Journal of Biological Chemistry45 citations Open access
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Haptoglobin-related protein and apolipoprotein AI are components of the two trypanolytic factors in human serum.
S. Tomlinson, Madhavi Muranjan, V. Nussenzweig, J. Raper
1997Molecular and biochemical parasitology (Print)44 citations Open access
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Cation channel conductance and pH gating of the innate immunity factor APOL1 are governed by pore-lining residues within the C-terminal domain
Charles Schaub, J. Verdi, Penny Lee, Nada Terra +3 more
2020Journal of Biological Chemistry41 citations Open access
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An M(r) 145,000 low-density lipoprotein (LDL)-binding protein is conserved throughout the Kinetoplastida order.
P. Bastin, André Stephan, J. Raper, J. Saint-Remy +2 more
1996Molecular and biochemical parasitology (Print)41 citations
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Biosynthesis, attachment and release of variant surface glycoproteins of the African trypanosome.
M. Turner, M. L. C. de Almeida, A. Gurnett, J. Raper +1 more
1985Current Topics in Microbiology and Immunology41 citations
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An investigation into the mechanism of trypanosome lysis by human serum factors.
Maria P. Molina Portela, J. Raper, S. Tomlinson
2000Molecular and biochemical parasitology (Print)39 citations
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Myristate exchange. A second glycosyl phosphatidylinositol myristoylation reaction in African trypanosomes.
L. Buxbaum, J. Raper, F. Opperdoes, P. T. Englund
1994Journal of Biological Chemistry38 citations Open access
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Activity of trypanosome lytic factor: a novel component of innate immunity
Russell Thomson, Marie Samanovic, J. Raper
2009Future Microbiology35 citations Open access
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A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense
Anneli Cooper, P. Capewell, C. Clucas, Nicola J. Veitch +4 more
2016PLoS Neglected Tropical Diseases31 citations Open access
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Transient expression of proteins by hydrodynamic gene delivery in mice.
Daniella Kovacsics, J. Raper
2014Journal of Visualized Experiments27 citations Open access
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Inducible Germline IgMs Bridge Trypanosome Lytic Factor Assembly and Parasite Recognition.
J. Verdi, Ronnie Zipkin, E. Hillman, R. A. Gertsch +5 more
2020Cell Host and Microbe20 citations Open access
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The lysis of Trypanosoma brucei brucei by human serum
S. Tomlinson, J. Raper
1996Nature Biotechnology18 citations
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Biosynthesis of glycosyl phosphatidylinositol protein anchors
T. Doering, J. Raper, L. Buxbaum, G. Hart +1 more
199018 citations Open access
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Coiled-coil binding of the leucine zipper domains of APOL1 is necessary for the open cation channel conformation
Charles Schaub, Penny Lee, Alisha Racho-Jansen, J. Giovinazzo +3 more
2021Journal of Biological Chemistry17 citations Open access
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Purification and characterisation of membrane-form variant surface glycoproteins of Trypanosoma brucei.
A. Gurnett, J. Ward, J. Raper, M. Turner
1986Molecular and biochemical parasitology (Print)16 citations
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Lack of correlation between haptoglobin concentration and trypanolytic activity of normal human serum.
J. Raper, V. Nussenzweig, S. Tomlinson
1996Molecular and biochemical parasitology (Print)15 citations Open access
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Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties
J. Pant, J. Giovinazzo, Lilit S Tuka, D. Pena +2 more
2021Journal of Biological Chemistry14 citations Open access
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Solution properties of the variant surface glycoprotein of Trypanosoma brucei.
A. Gurnett, J. Raper, Mervyn J. Turner
1986Molecular and biochemical parasitology (Print)14 citations
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Autoimmunity to phosphatidylserine and anemia in African Trypanosome infections
Juan Rivera-Correa, J. Verdi, Julian Sherman, J. Sternberg +2 more
2021PLoS Neglected Tropical Diseases12 citations Open access
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Possible localisation of dolichol-dependent mannosyltransferase of Trypanosoma brucei to the rough endoplasmic reticulum.
Maria Prado-Figueroa, J. Raper, F. Opperdoes
1994Molecular and biochemical parasitology (Print)12 citations
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All You Ever Wanted to Know About APOL1 and TLFs and Did Not Dare Ask.
J. Verdi, Charles Schaub, Russell Thomson, J. Raper
2020Methods in molecular biology9 citations
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Prophylactic antiparasitic transgenesis for human parasitic disease?
J. Lukeš, J. Raper
2010Molecular Therapy9 citations Open access
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Parasitology: Molecular one-upmanship
J. Raper, D. Friedman
2013Nature6 citations
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Cloning of the African indigenous cattle breed Kenyan Boran
Ming-Yan Yu, C. Muteti, M. Ogugo, W. Ritchie +2 more
2016Animal Genetics5 citations Open access
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BH 3 domain-independent apolipoprotein L 1 toxicity rescued by BCL 2 prosurvival proteins
J. Heneghan, D. Vandorpe, B. Shmukler, J. Giovinazzo +4 more
20155 citations
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Natural immunity to human African trypanosomiasis: trypanosome lytic factors and the blood incubation infectivity test.
J. Raper, Maria Pilar Portela Molina, Maria B. Redpath, S. Tomlinson +2 more
2002Transactions of the Royal Society of Tropical Medicine and Hygiene4 citations
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Glycosyl phosphatidylinositol membrane anchors in African trypanosomes.
K. Mensa-Wilmot, T. Doering, J. Raper, L. Buxbaum +3 more
19914 citations
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Abstracts from the UC Davis Transgenic Animal Research Conference X (TARC X)
J. Raper, Ron Zipkin, José Verdi, S. Suhr +13 more
2015Transgenic research3 citations
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Reservoir Modeling of Low-Sinuosity Channel Sands: A Network Approach
James H. Martin, A. J. Evans, J. Raper
19883 citations
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Characterization of a phospholipase C-resistant inositol containing glycolipid from Trypanosoma cruzi.
Norton Heise, J. Raper, M. L. Cardoso-de-Almeida
1994Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas2 citations
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