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Guzmán Álvarez · SciRah

Researcher profile · Semantic Scholar

Guzmán Álvarez

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Guzmán Álvarez — researcher profile on SciRah

h-index: 15
Works: 53
Citations: 675

Most-cited papers

5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene.
Alejandra Gerpe, Guzmán Álvarez, D. Benítez, L. Boiani +6 more
2009Bioorganic & Medicinal Chemistry50 citations
Semantic Scholar
Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity.
Guzmán Álvarez, Beatriz Aguirre-López, J. Varela, Mauricio Cabrera +11 more
2010European journal of medicinal chemistry47 citations Open access
Semantic Scholar
Optimization of antitrypanosomatid agents: identification of nonmutagenic drug candidates with in vivo activity.
Guzmán Álvarez, J. Varela, P. Márquez, Martín Gabay +13 more
2014Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity
Elena Aguilera, J. Varela, E. Birriel, E. Serna +14 more
2016ChemMedChem41 citations
Semantic Scholar
Caenorhabditis elegans Infrared-Based Motility Assay Identified New Hits for Nematicide Drug Development
G. Risi, Elena Aguilera, Enrique Ladós, G. Suárez +3 more
2019Veterinary Sciences39 citations Open access
Semantic Scholar
Identification of a New Amide-Containing Thiazole as a Drug Candidate for Treatment of Chagas' Disease
Guzmán Álvarez, J. Varela, Eugenia Cruces, Marcelo Fernández +11 more
2014Antimicrobial Agents and Chemotherapy38 citations Open access
Semantic Scholar
Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo.
Guzmán Álvarez, J. Martínez, J. Varela, E. Birriel +15 more
2015European journal of medicinal chemistry36 citations
Semantic Scholar
Molecular docking and molecular dynamics simulation studies of Trypanosoma cruzi triosephosphate isomerase inhibitors. Insights into the inhibition mechanism and selectivity.
L. Minini, Guzmán Álvarez, Mercedes González, H. Cerecetto +1 more
2015Journal of Molecular Graphics and Modelling33 citations
Semantic Scholar
Evaluating 5-Nitrofurans as Trypanocidal Agents
C. Bot, Belinda S Hall, Guzmán Álvarez, R. Di Maio +3 more
2013Antimicrobial Agents and Chemotherapy32 citations Open access
Semantic Scholar
Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp.
Guzmán Álvarez, C. Perdomo, C. Coronel, Elena Aguilera +10 more
2017Molecules27 citations Open access
Semantic Scholar
Trypanosoma cruzi chemical proteomics using immobilized benznidazole.
Andrea Trochine, Guzmán Álvarez, S. Corre, P. Faral-Tello +5 more
2014Experimental parasitology26 citations Open access
Semantic Scholar
New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: a deeper insight into the mechanism of inhibition
Guzmán Álvarez, J. Martínez, Beatriz Aguirre-López, N. Cabrera +8 more
2014Journal of Enzyme Inhibition and Medicinal Chemistry23 citations Open access
Semantic Scholar
Novel and Selective Rhipicephalus microplus Triosephosphate Isomerase Inhibitors with Acaricidal Activity
L. Saramago, H. Gomes, Elena Aguilera, H. Cerecetto +11 more
2018Veterinary Sciences20 citations Open access
Semantic Scholar
Isolation and Structural Characterization of Bioactive Molecules on Prostate Cancer from Mayan Traditional Medicinal Plants
R. Fort, Juan M. Trinidad Barnech, Juliette Dourron, M. Colazzo +3 more
2018Pharmaceuticals19 citations Open access
Semantic Scholar
Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity
F. Ferraro, Ileana Corvo, L. Bergalli, A. Ilarraz +9 more
2020Scientific Reports17 citations Open access
Semantic Scholar
A Nature-Inspired Design Yields a New Class of Steroids Against Trypanosomatids
Elena Aguilera, C. Perdomo, A. Espindola, Ileana Corvo +9 more
2019Molecules15 citations Open access
Semantic Scholar
Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment
Elena Aguilera, J. Varela, E. Serna, Susana Torres, +5 more
2018Memórias do Instituto Oswaldo Cruz14 citations Open access
Semantic Scholar
Synthesis and in vivo proof of concept of a BODIPY-based fluorescent probe as a tracer for biodistribution studies of a new anti-Chagas agent
Gonzalo Rodríguez, Javier Nargoli, A. López, G. Moyna +5 more
201714 citations Open access
Semantic Scholar
Novel tick glutathione transferase inhibitors as promising acaricidal compounds.
K. Ozelame, M. M. Mattia, L. A. D. Silva, L. Randall +5 more
2022Ticks and Tick-borne Diseases13 citations Open access
Semantic Scholar
1,2,4-thiadiazol-5(4H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition
Guzmán Álvarez, Beatriz Aguirre-López, N. Cabrera, Eliã B Marins +7 more
2013Journal of Enzyme Inhibition and Medicinal Chemistry13 citations Open access
Semantic Scholar
Antiprotozoal Compounds from Urolepis hecatantha (Asteraceae)
O. Elso, M. Clavin, N. Hernandez, Tomás Sgarlata +5 more
2021Evidence-Based Complementary and Alternative Medicine11 citations Open access
Semantic Scholar
3-H-[1,2]Dithiole as a New Anti-Trypanosoma cruzi Chemotype: Biological and Mechanism of Action Studies
Marcos Couto, C. Sánchez, B. Dávila, Valentina Machin +11 more
2015Molecules11 citations Open access
Semantic Scholar
Tautomerism and Rotamerism of Favipiravir and Halogenated Analogues in Solution and in the Solid State.
Angel H. Romero, Germán Fuentes, L. Suescun, O. Piro +7 more
2023Journal of Organic Chemistry10 citations
Semantic Scholar
Polypharmacology in the treatment of Chagas disease.
Elena Aguilera, Guzmán Álvarez, H. Cerecetto, Mercedes González
2018Current Medicinal Chemistry10 citations
Semantic Scholar
Crystal Structure of the Full-Length Feline Immunodeficiency Virus Capsid Protein Shows an N-Terminal β-Hairpin in the Absence of N-Terminal Proline
C. Folio, N. Sierra, M. Dujardin, Guzmán Álvarez +1 more
2017Viruses9 citations Open access
Semantic Scholar
Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro
Santiago Ruatta, Denis N. Prada Gori, Martín Fló Díaz, Franca Lorenzelli +55 more
2023Frontiers in Pharmacology8 citations Open access
Semantic Scholar
Looking for Novel Capsid Protein Multimerization Inhibitors of Feline Immunodeficiency Virus
N. Sierra, C. Folio, X. Robert, Mathieu Long +2 more
2018Pharmaceuticals7 citations Open access
Semantic Scholar
Pyrazol(in)e derivatives of curcumin analogs as a new class of anti-Trypanosoma cruzi agents.
Dimitris Matiadis, Tatiana Saporiti, Elena Aguilera, X. Robert +5 more
2021Future Medicinal Chemistry6 citations
Semantic Scholar
Identification of a Potential Inhibitor of the FIV p24 Capsid Protein and Characterization of Its Binding Site.
Mathieu Long, F. Cantrelle, X. Robert, E. Boll +5 more
2021Biochemistry5 citations Open access
Semantic Scholar
New Limonene-Hybrid Derivatives with Anti-T. cruzi Activity
Guzmán Álvarez, Alejandra Gerpe, D. Benítez, F. Garibotto +6 more
20105 citations
Semantic Scholar
Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours
Claudia Veira, Diego Benítez, Leticia Pérez‐Díaz, Guzmán Álvarez +2 more
2025Memórias do Instituto Oswaldo Cruz4 citations
Semantic Scholar
Anti-Trypanosoma cruzi Properties of Sesquiterpene Lactones Isolated from Stevia spp.: In Vitro and In Silico Studies
J. Borgo, O. Elso, Jessica Gómez, Mauro Coll +9 more
2023Pharmaceutics4 citations Open access
Semantic Scholar
Phenotypic and Target-Directed Screening Yields New Acaricidal Alternatives for the Control of Ticks
Tatiana Saporiti, M. Cabrera, Josefina Bentancur, M. Ferrari +8 more
2022Molecules4 citations Open access
Semantic Scholar
Preclinical Studies in Anti-Trypanosomatidae Drug Development
C. Perdomo, Elena Aguilera, Ileana Corvo, P. Faral-Tello +5 more
2021Pharmaceuticals4 citations Open access
Semantic Scholar
Effects of land cover changes on the water balance of the Palo Verde Wetland, Costa Rica
José Antônio, Guzmán Álvarez
20074 citations
Semantic Scholar
One-step synthesis of favipiravir from Selectfluor® and 3-hydroxy-2-pyrazinecarboxamide in an ionic liquid.
Germán Fuentes, M. F. García, H. Cerecetto, Guzmán Álvarez +2 more
2023Organic and biomolecular chemistry3 citations
Semantic Scholar
Preclinical Studies and Drug Combination of Low-Cost Molecules for Chagas Disease
Elena Aguilera, C. Sánchez, María Eugenia Cruces, B. Dávila +13 more
2022Pharmaceuticals2 citations Open access
Semantic Scholar
Identification of 2-(4-N,N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo
Guzmán Álvarez, L. van Pul, X. Robert, Zoraima Artía +6 more
2022BMC Pharmacology and Toxicology2 citations Open access
Semantic Scholar
Anaerobic Biotransformation of Nitro-Compounds to Amines by Bovine Rumen Fluid
A. Rodríguez, Ignacio Irazoqui, Guzmán Álvarez, C. Cajarville +3 more
20112 citations Open access
Semantic Scholar
Drug Targets: Screening for Small Molecules that Inhibit Fasciola hepatica Enzymes.
F. Ferraro, Mauricio Cabrera, Guzmán Álvarez, Ileana Corvo
2020Methods in molecular biology1 citations
Semantic Scholar
Back Cover: Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity (ChemMedChem 12/2016)
Elena Aguilera, J. Varela, E. Birriel, E. Serna +14 more
20161 citations
Semantic Scholar
Drug repurposing for Chagas disease: overcoming the hit-to-preclinical candidate stage
Claudia Veira, B. Dávila, E. Serna, Nilda Portillo +4 more
2025Frontiers in Chemical Biology0 citations Open access
Semantic Scholar
Advanced preclinical studies in canine leishmaniasis drug development
Guzmán Álvarez, C. Perdomo, Elena Aguilera, Ileana Corvo +4 more
20200 citations Open access
Semantic Scholar
Reactive plan execution in multi-agent environments
Guzmán Álvarez, C. Augusto
20190 citations Open access
Semantic Scholar
Análisis comparativo de la caracterización del clima organizacional en hospitales públicos y privados.
Guzmán Álvarez, Luis Félipe
20180 citations
Semantic Scholar
Phenotypic Screening on ‘Pathogen Box’ Yielded Novel Antiparasitic Compounds in Leishmania infantum
P. Faral-Tello, C. Robello, Guzmán Álvarez
20170 citations Open access
Semantic Scholar
Crystal structure of the full-length Feline Immunodeficiency Virus capsid protein unveils original features
C. Folio, N. Sierra, M. Dujardin, Guzmán Álvarez +1 more
20170 citations
Semantic Scholar
Looking for Novel p24 Multimerization Inhibitors of FIV
N. Sierra, C. Folio, C. Guillon, Guzmán Álvarez
20170 citations Open access
Semantic Scholar
Searching Bioactive Molecules in Prostate Cancer from Mayan Traditional Medicinal Plants
J. Trinidad, R. Fort, Juliette Dourron, F. Aguirre +2 more
20170 citations Open access
Semantic Scholar
Arylideneketones with Potent Trypanosomicidal Activity that Causes Late Apoptosis/Necrosis Like Nifurtimox
Elena Aguilera, F. Mosquillo, Leticia Pérez, H. Cerecetto +2 more
20170 citations Open access
Semantic Scholar

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