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H. V. van Wyk · SciRah

Researcher profile · Semantic Scholar

H. V. van Wyk

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H. V. van Wyk — researcher profile on SciRah

h-index: 13
Works: 34
Citations: 728

Most-cited papers

The role of tumour budding in predicting survival in patients with primary operable colorectal cancer: a systematic review.
H. V. van Wyk, J. Park, C. Roxburgh, P. Horgan +2 more
2015Cancer Treatment Reviews121 citations
Semantic Scholar
The Relationship Between Tumor Budding, Tumor Microenvironment, and Survival in Patients with Primary Operable Colorectal Cancer
H. V. van Wyk, A. Roseweir, P. Alexander, J. Park +3 more
2019Annals of Surgical Oncology85 citations Open access
Semantic Scholar
The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer
H. V. van Wyk, J. Park, J. Edwards, P. Horgan +2 more
2016British Journal of Cancer60 citations Open access
Semantic Scholar
The detection and role of lymphatic and blood vessel invasion in predicting survival in patients with node negative operable primary colorectal cancer.
H. V. van Wyk, C. Roxburgh, P. Horgan, Alan F Foulis +1 more
2014Critical reviews in oncology/hematology56 citations
Semantic Scholar
Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer
J. H. Park, H. V. van Wyk, C. Roxburgh, P. Horgan +2 more
2017British Journal of Cancer55 citations Open access
Semantic Scholar
The role of perineural invasion in predicting survival in patients with primary operable colorectal cancer: A systematic review.
H. V. van Wyk, J. Going, P. Horgan, D. McMillan
2017Critical reviews in oncology/hematology52 citations Open access
Semantic Scholar
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors
K. Pennel, Phimmada Hatthakarnkul, C. Wood, Guang-Yu Lian +35 more
2024Journal of experimental & clinical cancer research : CR47 citations Open access
Semantic Scholar
Signal Transduction and Activator of Transcription-3 (STAT3) in Patients with Colorectal Cancer: Associations with the Phenotypic Features of the Tumor and Host
J. Park, H. V. van Wyk, D. McMillan, Jean A. Quinn +4 more
2016Clinical Cancer Research45 citations Open access
Semantic Scholar
Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
C. Wood, K. Pennel, H. Leslie, A. Legrini +15 more
2023Cancer Research35 citations Open access
Semantic Scholar
A novel tumor‐based epithelial‐to‐mesenchymal transition score that associates with prognosis and metastasis in patients with Stage II/III colorectal cancer
A. Roseweir, Chia Y. Kong, J. Park, Lindsay Bennett +7 more
2018International Journal of Cancer30 citations Open access
Semantic Scholar
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer
P. Alexander, A. Roseweir, K. Pennel, H. V. van Wyk +15 more
2020British Journal of Cancer24 citations Open access
Semantic Scholar
Preoperative, biopsy‐based assessment of the tumour microenvironment in patients with primary operable colorectal cancer
J. Park, H. V. van Wyk, D. McMillan, J. Edwards +3 more
2019The Journal of Pathology: Clinical Research20 citations Open access
Semantic Scholar
CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer
K. Pennel, Jean A. Quinn, C. Nixon, Jitwadee Inthagard +12 more
2022The Journal of Pathology: Clinical Research15 citations Open access
Semantic Scholar
Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer
A. Roseweir, Arfon G. M. T. Powell, Lindsay Bennett, H. V. van Wyk +4 more
2016OncoTarget12 citations Open access
Semantic Scholar
Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer
Phimmada Hatthakarnkul, A. Ammar, K. Pennel, L. Officer-Jones +13 more
2023Journal of Cancer11 citations Open access
Semantic Scholar
Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer.
Phimmada Hatthakarnkul, Jean A. Quinn, A. Ammar, G. Lynch +4 more
2022Clinical science11 citations Open access
Semantic Scholar
Systematic review of tumour budding and association with common mutations in patients with colorectal cancer.
Phimmada Hatthakarnkul, Jean A. Quinn, A. Matly, A. Ammar +3 more
2021Critical reviews in oncology/hematology10 citations Open access
Semantic Scholar
The role of faecal calprotectin in the identification of colorectal neoplasia in patients attending for screening colonoscopy
Fionagh Ross, J. Park, D. Mansouri, Cariss Little +6 more
2021Colorectal Disease10 citations Open access
Semantic Scholar
Comparison of Methods to Identify Lymphatic and Blood Vessel Invasion and their Prognostic Value in Patients with Primary Operable Colorectal Cancer.
H. V. van Wyk, A. Foulis, C. Roxburgh, C. Orange +2 more
2015Anticancer Research9 citations
Semantic Scholar
Histopathological tumour microenvironment score independently predicts outcome in primary operable colorectal cancer
Phimmada Hatthakarnkul, K. Pennel, P. Alexander, H. V. van Wyk +10 more
2024The Journal of Pathology: Clinical Research8 citations Open access
Semantic Scholar
The relationship between the Glasgow Microenvironment Score and Markers of Epithelial-to-Mesenchymal Transition in TNM II-III Colorectal Cancer.
P. Alexander, A. Matly, Niphat Jirapongwattana, K. Pennel +9 more
2022Human Pathology5 citations Open access
Semantic Scholar
The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer
P. Alexander, H. V. van Wyk, K. Pennel, J. Hay +5 more
2022British Journal of Cancer5 citations Open access
Semantic Scholar
Abstract 5558: Understanding the molecular mechanism of tumor budding and its relationship with tumor microenvironment in colorectal cancer
Phimmada Hatthakarnkul, H. Leslie, H. V. van Wyk, L. Officer-Jones +11 more
2023Cancer Research2 citations
Semantic Scholar
Investigation of three alternative histopathological scoring methods at the invasive tumour front in colorectal cancer
Walaiphorn Woraharn, A. McCulloch, Christopher Bigley, Phimmada Hatthakarnkul +10 more
2025The Journal of Pathology: Clinical Research1 citations Open access
Semantic Scholar
The relationship between the non-canonical NF-κB pathway, tumour microenvironment, systemic inflammation and survival in patients undergoing surgery for colorectal caner.
Meera Patel, Lindsay Bennett, Jean A. Quinn, H. V. van Wyk +5 more
20171 citations
Semantic Scholar
Epithelial Plasticity and an Immune Suppressive Microenvironment Underpin Tumour Budding in Colorectal Cancer
Phimmada Hatthakarnkul, N. Fisher, Leonor Schubert Santana, H. Leslie +25 more
2026bioRxiv0 citations
Semantic Scholar
Correction: JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal‑rich
K. Pennel, Phimmada Hatthakarnkul, C. Wood, Guang-Yu Lian +35 more
2026Journal of experimental & clinical cancer research : CR0 citations Open access
Semantic Scholar
1253 The underlying molecular mechanisms of tumour budding and its relationship with tumour microenvironment
Phimmada Hatthakarnkul, H. Leslie, Leonor Schubert Santana, A. Legrini +17 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Histological Tumour Microenvironment Score Independently Predicts Outcome in Primary Operable Colorectal Cancer
Phimmada Hatthakarnkul, K. Pennel, P. Alexander, H. V. van Wyk +9 more
2023Social Science Research Network0 citations
Semantic Scholar
Spatially Resolved Transcriptomics Deconvolutes Histological Prognostic Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
C. Wood, K. Pennel, H. Leslie, A. Legrini +15 more
2022bioRxiv0 citations Open access
Semantic Scholar
Validation of the Glasgow Microenvironment Score in patients with colon cancer: A pathology-based prognostic tool.
P. Alexander, A. Roseweir, K. Pennel, H. V. van Wyk +6 more
20200 citations
Semantic Scholar
Effect of phenotype on outcome in synchronously resected primary colorectal cancer and matched liver metastases.
K. Pennel, C. Steele, Jean A. Quinn, A. Roseweir +9 more
20200 citations
Semantic Scholar
The relationship between tumor location, tumor microenvironment, systemic inflammation, and cancer-specific survival in patients undergoing surgery for colon cancer.
Meera Patel, J. Park, H. V. van Wyk, J. Edwards +2 more
20170 citations
Semantic Scholar
Abstract A130: The association between markers of tumor cell metabolism, the tumor microenvironment, and outcomes in patients with colorectal cancer
S. McSorley, Jennifer L. Clark, H. V. van Wyk, P. Horgan +3 more
20160 citations
Semantic Scholar

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P. Horgan×22
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J. Park×19
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C. Roxburgh×19
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