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William C. Chang · SciRah

Researcher profile · Semantic Scholar

William C. Chang

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William C. Chang — researcher profile on SciRah

h-index: 15
Works: 32
Citations: 861

Most-cited papers

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
M. Joyce, Wei-Hung Chen, R. Sankhala, A. Hajduczki +56 more
2021Cell Reports129 citations Open access
Semantic Scholar
A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates
M. Joyce, Hannah A. D. King, Ines Elakhal-Naouar, Aslaa Ahmed +54 more
2021Science Translational Medicine128 citations Open access
Semantic Scholar
Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations
V. Dussupt, R. Sankhala, Letzibeth Mendez-Rivera, Samantha M. Townsley +42 more
2021Nature Immunology66 citations Open access
Semantic Scholar
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
Hannah A. D. King, M. Joyce, Ines Lakhal-Naouar, Aslaa Ahmed +53 more
2021Proceedings of the National Academy of Sciences of the United States of America62 citations Open access
Semantic Scholar
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
M. Joyce, Wei-Hung Chen, R. Sankhala, A. Hajduczki +54 more
2021bioRxiv61 citations Open access
Semantic Scholar
SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses
Joshua M. Carmen, S. Shrivastava, Zhongyan Lu, Alexander Anderson +13 more
2021npj Vaccines54 citations Open access
Semantic Scholar
NPP4 is a procoagulant enzyme on the surface of vascular endothelium.
R. Albright, William C. Chang, D. Robert, D. Ornstein +6 more
2012Blood44 citations Open access
Semantic Scholar
Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke*♦
R. Albright, D. Ornstein, Wen-Xiang Cao, William C. Chang +8 more
2013Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity
Wei-Hung Chen, A. Hajduczki, E. Martinez, Hong-Jun Bai +41 more
2023Nature Communications39 citations Open access
Semantic Scholar
Kinetic Analysis of Autotaxin Reveals Substrate-specific Catalytic Pathways and a Mechanism for Lysophosphatidic Acid Distribution*
Lauren P. Saunders, Wen-Xiang Cao, William C. Chang, R. Albright +2 more
2011Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity
J. Jensen, R. Sankhala, V. Dussupt, Hong-Jun Bai +28 more
2023Journal of Virology28 citations Open access
Semantic Scholar
A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model
S. Johnston, K. Ricks, Ines Lakhal-Naouar, A. Jay +40 more
2022bioRxiv28 citations Open access
Semantic Scholar
Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates
M. Joyce, Hannah A. D. King, Ines Elakhal Naouar, Aslaa Ahmed +55 more
2021bioRxiv25 citations Open access
Semantic Scholar
Synergy Between Tissue Factor and Exogenous Factor XIa in Initiating Coagulation
K. Leiderman, William C. Chang, M. Ovanesov, A. Fogelson
2016Arteriosclerosis, Thrombosis and Vascular Biology18 citations Open access
Semantic Scholar
SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies
S. Shrivastava, Joshua M. Carmen, Zhongyan Lu, Shraddha Basu +24 more
2023npj Vaccines17 citations Open access
Semantic Scholar
Antibody Targeting of Conserved Sites of Vulnerability on the SARS-CoV-2 Spike Receptor-Binding Domain
R. Sankhala, V. Dussupt, Wei-Hung Chen, Hong-Jun Bai +41 more
2023Structure15 citations Open access
Semantic Scholar
Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques
R. Sankhala, Kerri G. Lal, Jaime L. Jensen, V. Dussupt +47 more
2024Nature Communications13 citations Open access
Semantic Scholar
Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques
Jing-You Yu, P. Thomas, Michaela Sciacca, Cindy Wu +36 more
2023Cell Reports Medicine12 citations Open access
Semantic Scholar
Interconnectedness of global hemostasis assay parameters in simultaneously evaluated thrombin generation, fibrin generation and clot lysis in normal plasma.
Kevin Z. Xin, William C. Chang, M. Ovanesov
2016Thrombosis Research12 citations Open access
Semantic Scholar
Modified aptamers as reagents to characterize recombinant human erythropoietin products
Wojciech Jankowski, H. A. Daniel Lagasse, William C. Chang, J. McGill +4 more
2020Scientific Reports9 citations Open access
Semantic Scholar
A spike-ferritin nanoparticle vaccine induces robust innate immune activity and drives polyfunctional SARS-CoV-2-specific T cells
Joshua M. Carmen, S. Shrivastava, Zhongyan Lu, Alexander Anderson +13 more
2021bioRxiv8 citations Open access
Semantic Scholar
Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN
Jing-You Yu, P. Thomas, K. McMahan, Catherine Jacob-Dolan +38 more
2022Science Advances5 citations Open access
Semantic Scholar
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
Hannah A. D. King, M. Joyce, Ines Elakhal Naouar, Aslaa Ahmed +53 more
2021bioRxiv5 citations Open access
Semantic Scholar
Comparative Analysis of Thrombin Calibration Algorithms and Correction for Thrombin-α2macroglobulin Activity
William C. Chang, Joseph W. Jackson, K. Machlus, A. Wolberg +1 more
2020Journal of Clinical Medicine5 citations Open access
Semantic Scholar
SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity
E. Martinez, William C. Chang, Wei-Hung Chen, A. Hajduczki +32 more
2024iScience3 citations Open access
Semantic Scholar
Fluorescence artifact correction in the thrombin generation assay: Necessity for correction algorithms in procoagulant samples
William C. Chang, Joseph W. Jackson, K. Machlus, A. Wolberg +1 more
2021Research and Practice in Thrombosis and Haemostasis3 citations Open access
Semantic Scholar
Production of Clinical-Grade SARS-CoV-2 Spike Ferritin Nanoparticle Protein Immunogen by Transient Transfection
A. Hajduczki, William C. Chang, Rafael A. De La Barrera, J. F. Wood +32 more
2025Vaccines2 citations Open access
Semantic Scholar
Skin Immunization With ALFQ-Adjuvanted SARS-CoV-2-Spike Ferritin Nanoparticles Induces Broad and Durable Immunity in Young and Aged Mice 2259612
Sanpreet Singh, Stephen C. Balmert, Saniya Mahendiratta, C. Carey +8 more
2026Journal of Immunology0 citations Open access
Semantic Scholar
Journal Pre-proof Ad26.COV2.S and SARS-CoV-2 Spike Protein Ferritin Nanoparticle Vaccine Protect Against SARS-CoV-2 Omicron BA.5 Challenge in Macaques
Julia Barrett, R. Camille, Mazurek, William C. Chang +10 more
20230 citations
Semantic Scholar
Abstract 345: Detection of Hypercoagulant Condition Caused by Elevated Prothrombin With a Thrombin Generation Assay
William C. Chang, K. Machlus, A. Wolberg, M. Ovanesov
20170 citations
Semantic Scholar
Characterization of Nucleotide Pyrophosphatase/Phosphodiesterase 4, a Dinucleotide Hydrolase, and Its Promotion of Platelet Aggregation
William C. Chang
20120 citations
Semantic Scholar
Molecular Structure and Biological Activity of NPP-4, An Endothelial Cell Surface Pyrophosphatase/ Phosphodiesterase That Stimulates Platelet Aggregation and Secretion Via Liberation of ADP Upon Hydrolysis of Diadenosine Triphosphate
D. Ornstein, R. Albright, William C. Chang, D. Robert +3 more
20110 citations
Semantic Scholar

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