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A. Dosne · SciRah

Researcher profile · Semantic Scholar

A. Dosne

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A. Dosne — researcher profile on SciRah

h-index: 11
Works: 28
Citations: 598

Most-cited papers

Improving the estimation of parameter uncertainty distributions in nonlinear mixed effects models using sampling importance resampling
A. Dosne, M. Bergstrand, K. Harling, M. Karlsson
2016Journal of Pharmacokinetics and Pharmacodynamics242 citations Open access
Semantic Scholar
An automated sampling importance resampling procedure for estimating parameter uncertainty
A. Dosne, M. Bergstrand, M. Karlsson
2017Journal of Pharmacokinetics and Pharmacodynamics139 citations Open access
Semantic Scholar
Erdafitinib (ERDA; JNJ-42756493), a pan-fibroblast growth factor receptor (FGFR) inhibitor, in patients (pts) with metastatic or unresectable urothelial carcinoma (mUC) and FGFR alterations (FGFRa): Phase 2 continuous versus intermittent dosing.
Y. Loriot, A. Necchi, S. Park, J. García-Donas +14 more
201832 citations
Semantic Scholar
A strategy for residual error modeling incorporating scedasticity of variance and distribution shape
A. Dosne, M. Bergstrand, M. Karlsson
2015Journal of Pharmacokinetics and Pharmacodynamics31 citations Open access
Semantic Scholar
Considerations for Industry—Preparing for the FDA Model‐Informed Drug Development (MIDD) Paired Meeting Program
Gerald R. Galluppi, M. Ahamadi, Souvik Bhattacharya, Nageshwar Budha +12 more
2024Clinical pharmacology and therapy23 citations Open access
Semantic Scholar
Erdafitinib’s effect on serum phosphate justifies its pharmacodynamically guided dosing in patients with cancer
A. Dosne, Elodie Valade, K. Stuyckens, P. de Porre +8 more
2021CPT: Pharmacometrics & Systems Pharmacology15 citations Open access
Semantic Scholar
dOFV distributions: a new diagnostic for the adequacy of parameter uncertainty in nonlinear mixed-effects models applied to the bootstrap
A. Dosne, Ronald Niebecker, M. Karlsson
2016Journal of Pharmacokinetics and Pharmacodynamics15 citations Open access
Semantic Scholar
Plasma and Liver Pharmacokinetics of the N-Acetylgalactosamine Short Interfering RNA JNJ-73763989 in Recombinant Adeno-Associated–Hepatitis B Virus–Infected Mice
Louis Sandra, Huybrecht T'jollyn, N. Goeyvaerts, A. Vermeulen +2 more
2022Journal of Pharmacology and Experimental Therapeutics14 citations Open access
Semantic Scholar
Population Pharmacokinetics of Total and Free Erdafitinib in Adult Healthy Volunteers and Cancer Patients: Analysis of Phase 1 and Phase 2 Studies
A. Dosne, Elodie Valade, K. Stuyckens, Li-Lian Y. Li +2 more
2019Journal of clinical pharmacology14 citations
Semantic Scholar
A translational model-based approach to inform the choice of the dose in phase 1 oncology trials: the case study of erdafitinib
E. Tosca, N. Terranova, K. Stuyckens, A. Dosne +7 more
2021Cancer Chemotherapy and Pharmacology13 citations
Semantic Scholar
Challenging the Norm: A Multidisciplinary Perspective on Intravenous to Subcutaneous Bridging Strategies for Biologics
Sihem Ait-Oudhia, Yow-Ming C. Wang, A. Dosne, Amit Roy +8 more
2023Clinical pharmacology and therapy11 citations Open access
Semantic Scholar
Exposure–response analyses of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma
A. Dosne, Elodie Valade, N. Goeyvaerts, P. de Porre +5 more
2022Cancer Chemotherapy and Pharmacology8 citations Open access
Semantic Scholar
Population pharmacokinetics and exposure–response analyses of daratumumab plus pomalidomide/dexamethasone in relapsed or refractory multiple myeloma
A. Dosne, Xia Li, Man Luo, I. Nnane +10 more
2022British Journal of Clinical Pharmacology8 citations Open access
Semantic Scholar
Assessment of the effect of erdafitinib on cardiac safety: analysis of ECGs and exposure–QTc in patients with advanced or refractory solid tumors
Elodie Valade, A. Dosne, Hong Xie, R. Kleiman +3 more
2019Cancer Chemotherapy and Pharmacology8 citations
Semantic Scholar
Development and validation of a time-varying correction factor for QT interval assessment in drug-resistant tuberculosis patients
Thanakorn Vongjarudech, A. Dosne, B. Remmerie, K. Dooley +5 more
2025International Journal of Antimicrobial Agents6 citations Open access
Semantic Scholar
A Population Pharmacokinetic Model of Macitentan and Its Active Metabolite Aprocitentan in Healthy Volunteers and Patients with Pulmonary Arterial Hypertension
R. Bartolucci, A. Dosne, D. Csonka, J. Pérez-Ruixo +2 more
2021Clinical Pharmacokinetics4 citations
Semantic Scholar
Establishing the Exposure‐QT Relationship During Bedaquiline Treatment Using a Time‐Varying Tuberculosis‐Specific Correction Factor (QTcTBT)
Thanakorn Vongjarudech, A. Dosne, B. Remmerie, M. O. Karlsson +1 more
2025CPT: Pharmacometrics & Systems Pharmacology3 citations Open access
Semantic Scholar
Effect of Carbamazepine on the Pharmacokinetics of Erdafitinib in Healthy Participants
Pharavee Jaiprasart, P. Hellemans, J. Jiao, A. Dosne +4 more
2024Clinical pharmacology in drug development3 citations Open access
Semantic Scholar
Nipocalimab Dose Selection for A Phase 3 Study in Adult Patients with Generalized Myasthenia Gravis (P1-5.018)
J. Pérez-Ruixo, Yao-Wei Zhu, M. Neyens, M. Jouvin +9 more
2023Sunday, April 233 citations
Semantic Scholar
Hyperphosphatemia due to erdafitinib (a pan-FGFR Inhibitor) and anti-tumour activity among patients (Pts) with advanced urothelial carcinoma (UC)
S. Tagawa, A. Siefker-Radtke, A. Dosne, B. Zhong +6 more
2019Annals of Oncology3 citations Open access
Semantic Scholar
Improving the estimation of parameter uncertainty distributions in nonlinear mixed effects models using sampling importance resampling
A. Dosne, M. Bergstrand, K. Harling, M. O. Karlsson
2016Journal of Pharmacokinetics and Pharmacodynamics2 citations Open access
Semantic Scholar
Nipocalimab Dose Selection in Generalized Myasthenia Gravis
Belén Valenzuela, Martine Neyens, Yaowei Zhu, S. Ramchandren +5 more
2025CPT: Pharmacometrics & Systems Pharmacology1 citations Open access
Semantic Scholar
Pharmacodynamic-Mediated Drug Disposition (PDMDD) Model of Daratumumab Monotherapy in Patients with Multiple Myeloma
Xia Li, A. Dosne, Carlos Pérez Ruixo, J. Pérez Ruixo
2023Clinical Pharmacokinetics1 citations
Semantic Scholar
Improved Methods for Pharmacometric Model-Based Decision-Making in Clinical Drug Development
A. Dosne
20161 citations
Semantic Scholar
Considerations for Industry—Preparing for the FDA Model-Informed Drug Development (MIDD) Paired Meeting Program
Souvik Bhattacharya, Gerald R. Galluppi, M. Ahamadi, Nageshwar Budha +12 more
Proceedings of the American Conference of Pharmacometrics 20241 citations Open access
Semantic Scholar
An automated sampling importance resampling procedure for estimating parameter uncertainty
A. Dosne, M. Bergstrand, M. O. Karlsson
2017Journal of Pharmacokinetics and Pharmacodynamics0 citations Open access
Semantic Scholar
Longitudinal Data Analysis Using Model Averaging: Benefits For Pivotal Clinical Trials, Applied To Rheumatoid Arthritis
A. Dosne, B. Bieth, M. Bergstrand, M. Karlsson +1 more
20160 citations
Semantic Scholar
Development of an interspecies whole-body physiologically based pharmacokinetic (WBPBPK) model for colistin methanesulfonate (CMS) and colistin in five animal species and evaluation of its predictive ability in human
S. Bouchène, A. Dosne, S. Marchand, L. Friberg +3 more
20160 citations
Semantic Scholar

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