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B. Knebel · SciRah

Researcher profile · Semantic Scholar

B. Knebel

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B. Knebel — researcher profile on SciRah

h-index: 31
Works: 112
Citations: 2,965

Most-cited papers

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial
S. Kahl, S. Gancheva, K. Strassburger, C. Herder +20 more
2019Diabetes Care321 citations Open access
Semantic Scholar
Liver-Specific Expression of Transcriptionally Active SREBP-1c Is Associated with Fatty Liver and Increased Visceral Fat Mass
B. Knebel, J. Haas, S. Hartwig, S. Jacob +4 more
2012PLoS ONE163 citations Open access
Semantic Scholar
Secretome profiling of primary human skeletal muscle cells.
S. Hartwig, Silja Raschke, B. Knebel, Mika Scheler +17 more
2014Biochimica et Biophysica Acta156 citations
Semantic Scholar
Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
T. Jelenik, K. Kaul, G. Séquaris, U. Flögel +12 more
2017Diabetes135 citations Open access
Semantic Scholar
Insulin-activated Erk-mitogen-activated Protein Kinases Phosphorylate Sterol Regulatory Element-binding Protein-2 at Serine Residues 432 and 455 in Vivo*
J. Kotzka, S. Lehr, Gunther Roth, H. Avci +2 more
2004Journal of Biological Chemistry121 citations Open access
Semantic Scholar
Exosomal proteins constitute an essential part of the human adipose tissue secretome.
S. Hartwig, Elisabetta de Filippo, S. Göddeke, B. Knebel +5 more
2019Biochimica et Biophysica Acta - Proteins and Proteomics102 citations
Semantic Scholar
Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene.
J. Brüning, J. Gillette, Yi Zhao, Christian Bjorbaeck +9 more
2000Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
Semantic Scholar
The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lower hirsutism score and increased insulin sensitivity in women with polycystic ovary syndrome
S. Hahn, A. Fingerhut, Ulyana Khomtsiv, Liliya Khomtsiv +7 more
2005Clinical Endocrinology71 citations
Semantic Scholar
Synthetic cytokine receptors transmit biological signals using artificial ligands
E. Engelowski, A. Schneider, M. Franke, Hai-Feng C. Xu +10 more
2018Nature Communications61 citations Open access
Semantic Scholar
Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.
B. Knebel, K. Strassburger, J. Szendroedi, J. Kotzka +10 more
2016Journal of Clinical Endocrinology and Metabolism57 citations
Semantic Scholar
Role of Patatin-Like Phospholipase Domain–Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes
O. Zaharia, K. Strassburger, B. Knebel, Y. Kupriyanova +10 more
2020Diabetes Care54 citations Open access
Semantic Scholar
Tissue-Specific Differences in the Development of Insulin Resistance in a Mouse Model for Type 1 Diabetes
T. Jelenik, G. Séquaris, K. Kaul, D. Ouwens +12 more
2014Diabetes54 citations Open access
Semantic Scholar
Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2
B. Knebel, S. Lehr, S. Hartwig, J. Haas +9 more
2014Archives of Physiology and Biochemistry52 citations Open access
Semantic Scholar
Increased low grade inflammatory serum markers in patients with Polycystic ovary syndrome (PCOS) and their relationship to PPARgamma gene variants.
B. Knebel, O. Janssen, S. Hahn, S. Jacob +3 more
2008Experimental and clinical endocrinology & diabetes51 citations
Semantic Scholar
Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity
J. Kotzka, B. Knebel, J. Haas, Lorena Kremer +4 more
2012PLoS ONE49 citations Open access
Semantic Scholar
Insulin Resistance and Vulnerability to Cardiac Ischemia
T. Jelenik, U. Flögel, Elisa Álvarez-Hernández, D. Scheiber +14 more
2018Diabetes48 citations Open access
Semantic Scholar
Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome
B. Knebel, P. Fahlbusch, Matthias Dille, Natalie Wahlers +9 more
2019Front. Cell Dev. Biol.43 citations Open access
Semantic Scholar
The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.
T. Hörbelt, B. Knebel, P. Fahlbusch, D. Barbosa +9 more
2019Biochimica et Biophysica Acta - Molecular Basis of Disease40 citations Open access
Semantic Scholar
Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.
J. Kotzka, B. Knebel, H. Avci, S. Jacob +5 more
2010Atherosclerosis40 citations
Semantic Scholar
Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men
P. Fahlbusch, B. Knebel, T. Hörbelt, D. Barbosa +9 more
2020International Journal of Molecular Sciences36 citations Open access
Semantic Scholar
Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis
D. Barbosa, P. Fahlbusch, Daniella Herzfeld de Wiza, S. Jacob +8 more
2020Scientific Reports36 citations Open access
Semantic Scholar
Lipodystrophies—Disorders of the Fatty Tissue
B. Knebel, D. Müller-Wieland, J. Kotzka
2020International Journal of Molecular Sciences36 citations Open access
Semantic Scholar
Peroxisomes compensate hepatic lipid overflow in mice with fatty liver.
B. Knebel, S. Hartwig, J. Haas, S. Lehr +8 more
2015Biochimica et Biophysica Acta35 citations
Semantic Scholar
A mutation in the c-Fos gene associated with congenital generalized lipodystrophy
B. Knebel, J. Kotzka, S. Lehr, S. Hartwig +9 more
2013Orphanet Journal of Rare Diseases33 citations Open access
Semantic Scholar
Effect of sterol regulatory element binding protein-1a on the mitochondrial protein pattern in human liver cells detected by 2D-DIGE.
S. Lehr, J. Kotzka, H. Avci, B. Knebel +6 more
2005Biochemistry33 citations
Semantic Scholar
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes
D. Ziegler, Alexander Strom, K. Strassburger, B. Knebel +4 more
2020Diabetologia31 citations Open access
Semantic Scholar
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes
D. Ziegler, E. Schleicher, Alexander Strom, B. Knebel +8 more
2017Diabetes/Metabolism Research Reviews30 citations Open access
Semantic Scholar
A variant of the glucose transporter gene SLC2A2 modifies the glycaemic response to metformin therapy in recently diagnosed type 2 diabetes
W. Rathmann, K. Strassburger, B. Bongaerts, O. Kuss +7 more
2018Diabetologia28 citations Open access
Semantic Scholar
Two novel mutations in the insulin binding subunit of the insulin receptor gene without insulin binding impairment in a patient with Rabson-Mendenhall syndrome.
C. Thiel, B. Knebel, I. Knerr, H. Sticht +5 more
2008Molecular Genetics and Metabolism28 citations
Semantic Scholar
Metabolic Determinants of Impaired Pulmonary Function in Patients with Newly Diagnosed Type 2 Diabetes Mellitus.
M. Röhling, D. Pesta, D. Markgraf, K. Strassburger +5 more
2018Experimental and clinical endocrinology & diabetes27 citations
Semantic Scholar
Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes
S. Gancheva, A. Bierwagen, K. Kaul, C. Herder +11 more
2016Diabetes26 citations
Semantic Scholar
Metabolic flexibility and oxidative capacity independently associate with insulin sensitivity in individuals with newly diagnosed type 2 diabetes
M. Apostolopoulou, K. Strassburger, C. Herder, B. Knebel +19 more
2016Diabetologia26 citations Open access
Semantic Scholar
Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle
O. Klymenko, T. Brecklinghaus, Matthias Dille, C. Springer +11 more
2020Molecular Metabolism25 citations Open access
Semantic Scholar
Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models
B. Knebel, Simon Goeddeke, G. Poschmann, D. Markgraf +9 more
2017International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
BOND study: a randomised double-blind, placebo-controlled trial over 12 months to assess the effects of benfotiamine on morphometric, neurophysiological and clinical measures in patients with type 2 diabetes with symptomatic polyneuropathy
G. Bönhof, Gundega Sipola, Alexander Strom, C. Herder +9 more
2022BMJ Open23 citations Open access
Semantic Scholar
Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes
B. Knebel, S. Hartwig, S. Jacob, Ulrike Kettel +6 more
2018International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health
S. Göddeke, B. Knebel, P. Fahlbusch, T. Hörbelt +10 more
2018International Journal of Obesity22 citations
Semantic Scholar
Synthetic interleukin 22 (IL-22) signaling reveals biological activity of homodimeric IL-10 receptor 2 and functional cross-talk with the IL-6 receptor gp130
Sofie Mossner, M. Kuchner, Nastaran Fazel Modares, B. Knebel +3 more
2020Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes
K. Weber, B. Knebel, K. Strassburger, J. Kotzka +5 more
2016Cardiovascular Diabetology20 citations Open access
Semantic Scholar
Synthetic Cargo Internalization Receptor System for Nanoparticle Tracking of Individual Cell Populations by Fluorine Magnetic Resonance Imaging.
S. Temme, Paul Baran, P. Bouvain, C. Grapentin +9 more
2018ACS Nano18 citations
Semantic Scholar
Identification of a gene variant in the master regulator of lipid metabolism SREBP-1 in a family with a novel form of severe combined hypolipidemia.
J. Kotzka, B. Knebel, O. Janssen, J. Schaefer +4 more
2011Atherosclerosis18 citations
Semantic Scholar
Insulin-regulated transcription factors: molecular link between insulin resistance and cardiovascular risk factors
D. Müller-Wieland, B. Knebel, H. Avci, S. Lehr +4 more
2001International Journal of Obesity18 citations
Semantic Scholar
Alteration of Liver Peroxisomal and Mitochondrial Functionality in the NZO Mouse Model of Metabolic Syndrome
B. Knebel, S. Göddeke, S. Hartwig, T. Hörbelt +8 more
2018PROTEOMICS - Clinical Applications16 citations
Semantic Scholar
Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes.
S. Görigk, D. Ouwens, T. Kuhn, D. Altenhofen +9 more
2022Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids14 citations
Semantic Scholar
Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations
T. Schallschmidt, Sandra Lebek, D. Altenhofen, M. Damen +12 more
2018Genetics14 citations Open access
Semantic Scholar
Long-term adjustment of hepatic lipid metabolism after chronic stress and the role of FGF21.
Matthias Dille, A. Nikolić, Natalie Wahlers, P. Fahlbusch +8 more
2021Biochimica et Biophysica Acta - Molecular Basis of Disease13 citations Open access
Semantic Scholar
Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus
K. Bódis, S. Kahl, M. Simon, Zhou Zhou +25 more
2018Nutrition & Diabetes13 citations Open access
Semantic Scholar
Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling
Nele Zoellner, Noémi Coesfeld, Frederik De Vos, Jennifer Denter +8 more
2022Frontiers in Microbiology12 citations Open access
Semantic Scholar
Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD
P. Fahlbusch, A. Nikolic, S. Hartwig, S. Jacob +7 more
2022International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes
D. Pesta, T. Jelenik, O. Zaharia, Pavel Bobrov +14 more
2021Frontiers in Endocrinology10 citations Open access
Semantic Scholar

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J. Kotzka — researcher profile on SciRah
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