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S. Bratton · SciRah

Researcher profile · Semantic Scholar

S. Bratton

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S. Bratton — researcher profile on SciRah

h-index: 20
Works: 42
Citations: 1,465

Most-cited papers

Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.
M. J. Miley, Agnieszka K. Zielinska, J. Keenan, S. Bratton +2 more
2007Journal of Molecular Biology196 citations Open access
Semantic Scholar
Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands
Krishna C. Chimalakonda, Kathryn A. Seely, S. Bratton, L. Brents +7 more
2012Drug Metabolism And Disposition182 citations Open access
Semantic Scholar
Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids
A. Mazur, Cheryl F. Lichti, P. Prather, Agnieszka K. Zielinska +6 more
2009Drug Metabolism And Disposition152 citations Open access
Semantic Scholar
The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families
A. Radomińska-Pandya, S. Bratton, M. Redinbo, M. J. Miley
2010Drug metabolism reviews (Softcover ed.)81 citations Open access
Semantic Scholar
Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
Krishna C. Chimalakonda, S. Bratton, Vi-Huyen Le, Kan Hui Yiew +5 more
2011Drug Metabolism And Disposition80 citations Open access
Semantic Scholar
Human UDP-Glucuronosyltransferase 1A5: Identification, Expression, and Activity
M. Finel, Xin Li, Dione A. Gardner-Stephen, S. Bratton +2 more
2005Journal of Pharmacology and Experimental Therapeutics72 citations
Semantic Scholar
International Journal of Nanomedicine Dovepress Ethylenediamine Functionalized-single-walled Nanotube (f-swnt)-assisted in Vitro Delivery of the Oncogene Suppressor P53 Gene to Breast Cancer Mcf-7 Cells
A. Karmakar, S. Bratton, E. Dervishi, Anindya Ghosh +7 more
64 citations
Semantic Scholar
LITHOCHOLIC ACID DECREASES EXPRESSION OF UGT2B7 IN CACO-2 CELLS: A POTENTIAL ROLE FOR A NEGATIVE FARNESOID X RECEPTOR RESPONSE ELEMENT
Yuan Lu, J. Heydel, Xin Li, S. Bratton +2 more
2005Drug Metabolism And Disposition61 citations Open access
Semantic Scholar
Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors
L. Brents, F. Medina-Bolivar, Kathryn A. Seely, Vipin A. Nair +7 more
2011Xenobiotica; the fate of foreign compounds in biological systems60 citations Open access
Semantic Scholar
A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years.
A. Radomińska-Pandya, S. Bratton, J. Little
2005Current drug metabolism60 citations
Semantic Scholar
Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases Published, JLR Papers in Press, July 1, 2004. DOI 10.1194/jlr.M400103-JLR200
J. Little, Mika Kurkela, J. Sonka, Sirkku Jäntti +4 more
2004Journal of Lipid Research57 citations Open access
Semantic Scholar
Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells
L. Saeed, M. Mahmood, Sebastian Pyrek, T. Fahmi +8 more
2014Journal of Applied Toxicology50 citations Open access
Semantic Scholar
Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis.
Yan Xiong, D. Bernardi, S. Bratton, M. Ward +4 more
2006Biochemistry44 citations
Semantic Scholar
Glucuronidation of Monohydroxylated Warfarin Metabolites by Human Liver Microsomes and Human Recombinant UDP-Glucuronosyltransferases
Agnieszka K. Zielinska, Cheryl F. Lichti, S. Bratton, Neil C. Mitchell +6 more
2008Journal of Pharmacology and Experimental Therapeutics41 citations Open access
Semantic Scholar
Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10.
Athena Starlard-Davenport, Yan Xiong, S. Bratton, Anna Gallus‐Zawada +2 more
2007Steroids38 citations Open access
Semantic Scholar
CB1 and CB2 Receptors are Novel Molecular Targets for Tamoxifen and 4OH-Tamoxifen
P. Prather, FeAna FrancisDevaraj, C. Dates, Aleksandra K. Greer +4 more
2013Biochemical and Biophysical Research Communications - BBRC31 citations Open access
Semantic Scholar
Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines
C. Dates, T. Fahmi, Sebastian Pyrek, A. Yao-Borengasser +6 more
2015Cancer Biology & Therapy27 citations Open access
Semantic Scholar
Nanodelivery of Parthenolide Using Functionalized Nanographene Enhances its Anticancer Activity
A. Karmakar, Yang Xu, Thikra A. Mustafa, Ganesh K. Kannarpady +4 more
2014RSC Advances23 citations Open access
Semantic Scholar
The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
Yan Xiong, A. Patana, M. J. Miley, Agnieszka K. Zielinska +6 more
2008Drug Metabolism And Disposition22 citations Open access
Semantic Scholar
Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10
Barbara Fedejko-Kap, S. Bratton, M. Finel, A. Radomińska-Pandya +1 more
2012Drug Metabolism And Disposition21 citations Open access
Semantic Scholar
Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases
S. Bratton, Carrie M. Mosher, Farid Khallouki, M. Finel +3 more
2012Journal of Pharmacology and Experimental Therapeutics20 citations Open access
Semantic Scholar
Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.
Xin Li, S. Bratton, A. Radomińska-Pandya
2007Drug Metabolism and Pharmacokinetics20 citations Open access
Semantic Scholar
Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells.
Yuan Lu, S. Bratton, J. Heydel, A. Radomińska-Pandya
2008Drug Metabolism and Pharmacokinetics19 citations Open access
Semantic Scholar
Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
G. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, A. Mazur +5 more
2008Drug Metabolism And Disposition16 citations Open access
Semantic Scholar
A Potential Role for Human UDP-Glucuronosyltransferase 1A4 Promoter Single Nucleotide Polymorphisms in the Pharmacogenomics of Tamoxifen and Its Derivatives
Aleksandra K. Greer, C. Dates, Athena Starlard-Davenport, V. Edavana +5 more
2014Drug Metabolism And Disposition12 citations Open access
Semantic Scholar
Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases
Aleksandra K. Greer, N. Madadi, S. Bratton, Sarah Eddy +4 more
2014Chemical Research in Toxicology11 citations Open access
Semantic Scholar
Nanodelivery of gambogic acid by functionalized graphene enhances inhibition of cell proliferation and induces G0/G1 cell cycle arrest in cervical, ovarian, and prostate cancer cells
L. Saeed, M. Mahmood, Yang Xu, Z. Nima +8 more
20155 citations
Semantic Scholar
Functionalized‐single‐walled nanotube (f‐SWNT)‐assisted in vitro delivery of the oncogene suppressor genes to cancer cells
A. Radomińska-Pandya, A. Karmakar, S. Bratton, Yang Xu +3 more
20121 citations
Semantic Scholar
A potential role for human UDP‐glucuronosyltransferase 1A4 promoter SNPs in the pharmacogenomics of Tamoxifen and its derivatives (1141.13)
C. Dates, Aleksandra K. Greer, S. Bratton, Vineetha Koroth Edavana +2 more
20140 citations
Semantic Scholar
DMD058016 1392..1400
Aleksandra K. Greer, C. Dates, Athena Starlard-Davenport, V. Edavana +6 more
20140 citations
Semantic Scholar
Glucuronides of antitumor agents C‐1311 and C‐1305 modulate cytotoxicity in cancer cells
M. Pawłowska, R. Chu, S. Bratton, E. Augustin +3 more
20120 citations
Semantic Scholar
Conjugation of synthetic cannabinoids in K2/Spice by human UDP‐glucuronosyltransferase (UGTs)
A. Radomińska-Pandya, Kan Hui Nicole Yiew, S. Bratton, Vi-Huyen Le +4 more
20110 citations
Semantic Scholar
Oxidation of abused synthetic cannabinoids in K2/Spice by human cytochromes P450
A. Radomińska-Pandya, S. Bratton, S. Chib, John M. Blevins +4 more
20110 citations
Semantic Scholar
Human UDP‐glucuronosyltransferases (UGTs) are involved in the metabolism of the natural resveratrol analogues arachidin‐1, arachidin‐3 and piceatannol
A. Radomińska-Pandya, Vipin A. Nair, S. Bratton, Anna E. Gallus-Zawada +2 more
20100 citations
Semantic Scholar
Targeted nanoparticle delivery of tumor suppressing UDP‐glucuronosyltransferase (UGT) genes into cancer cells
A. Radomińska-Pandya, A. Karmakar, S. Bratton, Xu Yang +3 more
20100 citations Open access
Semantic Scholar
Comparative characterization of UDP‐glucuronic acid (UDP‐GlcUA) binding‐site directed inhibitors with human UGT2B7 and 1A10.
S. Bratton, L. Laakkonen, A. Patana, A. Mazur +3 more
20090 citations
Semantic Scholar
The glucuronidation of native and oxidized estrogens can be effectively inhibited by compounds structurally related to UDP‐glucuronic acid in human recombinant UGT1A10
A. Mazur, S. Bratton, G. Miller, M. Finel +1 more
20090 citations
Semantic Scholar
Human hepatic and extrahepatic UDP‐glucuronosyltransferase (UGTs) enzymes involved in the metabolism of cannabinoids
A. Radomińska-Pandya, A. Mazur, Cheryl F. Lichti, Anna Gallus‐Zawada +3 more
20080 citations
Semantic Scholar
Identification of hydroxywarfarin binding site in human UGT1A10: Phenylalanine 90 is crucial for the glucuronidation of 6- and 7-hydroxy- but not 8- hydroxywarfarin*
G. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, A. Mazur +6 more
20080 citations
Semantic Scholar
Glucuronidation of Warfarin Metabolites by Human Recombinant UDP‐Glucuronosyltransferases (UGTs)
Agnieszka K. Zielinska, Cheryl F. Lichti, S. Bratton, Anna Gallus‐Zawada +4 more
20070 citations
Semantic Scholar
Aspartic Acid393 of the DxxD Motif within The C‐Terminal Region of Human UDP‐Glucuronosyltransferase 1A10 is Critical to the Binding of UDP‐Glucuronic Acid
A. Radomińska-Pandya, Yan Xiong, S. Bratton, Agnieszka K. Zielinska +1 more
20070 citations
Semantic Scholar
Phe90 is a crucial amino acid within the estrogen binding site of the human UDP‐glucuronosyltransferase 1A10
Athena Starlard-Davenport, S. Bratton, M. Finel, A. Radomińska-Pandya
20060 citations
Semantic Scholar

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