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C. Sykes · SciRah

Researcher profile · Semantic Scholar

C. Sykes

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C. Sykes — researcher profile on SciRah

h-index: 24
Works: 84
Citations: 1,965

Most-cited papers

A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine.
M. Cottrell, Kuo Yang, Heather M. A. Prince, C. Sykes +10 more
2016Journal of Infectious Diseases293 citations Open access
Semantic Scholar
Ultra-long-acting tunable biodegradable and removable controlled release implants for drug delivery
S. R. Benhabbour, M. Kovárová, Clinton L. Jones, Daijha J. Copeland +14 more
2019Nature Communications140 citations Open access
Semantic Scholar
Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART
P. W. Denton, Julie M. Long, S. Wietgrefe, C. Sykes +13 more
2014PLoS Pathogens114 citations Open access
Semantic Scholar
Ultra-long-acting removable drug delivery system for HIV treatment and prevention
M. Kovárová, S. R. Benhabbour, I. Massud, Rae Ann Spagnuolo +8 more
2018Nature Communications87 citations Open access
Semantic Scholar
Quantitative mass spectrometry imaging of emtricitabine in cervical tissue model using infrared matrix-assisted laser desorption electrospray ionization
Mark T. Bokhart, E. Rosen, Corbin G. Thompson, C. Sykes +2 more
2014Analytical and Bioanalytical Chemistry78 citations Open access
Semantic Scholar
Mass Spectrometry Imaging Reveals Heterogeneous Efavirenz Distribution within Putative HIV Reservoirs
Corbin G. Thompson, Mark T. Bokhart, C. Sykes, Lourdes Adamson +5 more
2015Antimicrobial Agents and Chemotherapy76 citations Open access
Semantic Scholar
Single-dose pharmacokinetics of tenofovir alafenamide and its active metabolite in the mucosal tissues
M. Cottrell, Katy L. Garrett, Heather M. A. Prince, C. Sykes +7 more
2017Journal of Antimicrobial Chemotherapy58 citations Open access
Semantic Scholar
Dolutegravir Pharmacokinetics in the Genital Tract and Colorectum of HIV Negative Men After Single and Multiple Dosing
Benjamin N. Greener, K. Patterson, Heather M. A. Prince, C. Sykes +7 more
2013Journal of Acquired Immune Deficiency Syndromes55 citations Open access
Semantic Scholar
Mapping antiretroviral drugs in tissue by IR-MALDESI MSI coupled to the Q Exactive and comparison with LC-MS/MS SRM Assay
J. Barry, Guillaume Robichaud, Mark T. Bokhart, Corbin G. Thompson +3 more
2014Journal of the American Society for Mass Spectrometry51 citations Open access
Semantic Scholar
Tenofovir Diphosphate and Emtricitabine Triphosphate Concentrations in Blood Cells Compared with Isolated Peripheral Blood Mononuclear Cells: A New Measure of Antiretroviral Adherence?
J. Adams, C. Sykes, P. Menezes, Heather M. A. Prince +6 more
2013Journal of Acquired Immune Deficiency Syndromes48 citations Open access
Semantic Scholar
Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species
Corbin G. Thompson, E. Rosen, Heather M. A. Prince, N. White +19 more
2019Science Translational Medicine44 citations Open access
Semantic Scholar
Analysis of Antiretrovirals in Single Hair Strands for Evaluation of Drug Adherence with Infrared-Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging
E. Rosen, Corbin G. Thompson, Mark T. Bokhart, Heather M. A. Prince +3 more
2015Analytical Chemistry44 citations Open access
Semantic Scholar
Decreased tenofovir diphosphate concentrations in a transgender female cohort: Implications for HIV pre-exposure prophylaxis (PrEP).
M. Cottrell, Heather M. A. Prince, A. Schauer, C. Sykes +10 more
2019Clinical Infectious Diseases42 citations Open access
Semantic Scholar
Single and Multiple Dose Pharmacokinetics of Dolutegravir in the Genital Tract of HIV Negative Women
J. Adams, K. Patterson, Heather M. A. Prince, C. Sykes +3 more
2013Antiviral Therapy41 citations Open access
Semantic Scholar
Antiretroviral Concentrations and Surrogate Measures of Efficacy in the Brain Tissue and CSF of Preclinical Species
N. Srinivas, E. Rosen, W. Gilliland, M. Kovárová +10 more
2018Xenobiotica; the fate of foreign compounds in biological systems40 citations Open access
Semantic Scholar
HIV Pre-Exposure Prophylaxis: Mucosal Tissue Drug Distribution of RT Inhibitor Tenofovir and Entry Inhibitor Maraviroc in a Humanized Mouse Model
M. Veselinovic, Kuo Yang, J. LeCureux, C. Sykes +3 more
2014Virology39 citations Open access
Semantic Scholar
Validation of an LC-MS/MS Assay to Simultaneously Monitor the Intracellular Active Metabolites of Tenofovir, Emtricitabine, and Lamivudine in Dried Blood Spots
A. Schauer, C. Sykes, M. Cottrell, Heather M. A. Prince +1 more
2017Journal of Pharmaceutical and Biomedical Analysis36 citations Open access
Semantic Scholar
Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes
Raju Khatri, J. K. Fallon, C. Sykes, Natasha Kulick +8 more
2021Frontiers in Pharmacology32 citations Open access
Semantic Scholar
Ultra-long-acting in-situ forming implants with cabotegravir protect female macaques against rectal SHIV infection
Isabella C. Young, I. Massud, M. Cottrell, Roopali Shrivastava +21 more
2023Nature Communications30 citations Open access
Semantic Scholar
HIV-1-RNA Decay and Dolutegravir Concentrations in Semen of Patients Starting a First Antiretroviral Regimen.
A. Imaz, J. Martinez-Picado, J. Niubó, A. Kashuba +8 more
2016Journal of Infectious Diseases30 citations Open access
Semantic Scholar
Pregnancy-Related Hormones Increase Nifedipine Metabolism in Human Hepatocytes by Inducing CYP3A4 Expression
Raju Khatri, Natasha Kulick, Rebecca J B Rementer, J. K. Fallon +10 more
2020Journal of Pharmacy and Science29 citations Open access
Semantic Scholar
Quantitative Analysis of Microbicide Concentrations in Fluids, Gels and Tissues Using Confocal Raman Spectroscopy
Oranat Chuchuen, Marcus H. Henderson, C. Sykes, M. Kim +2 more
2013PLoS ONE29 citations Open access
Semantic Scholar
Antiretroviral Drug Concentrations in Lymph Nodes: A Cross-Species Comparison of the Effect of Drug Transporter Expression, Viral Infection, and Sex in Humanized Mice, Nonhuman Primates, and Humans
E. Burgunder, J. K. Fallon, N. White, A. Schauer +9 more
2019Journal of Pharmacology and Experimental Therapeutics28 citations Open access
Semantic Scholar
A Pharmacokinetic/Pharmacodynamic Model to Predict Effective HIV Prophylaxis Dosing Strategies for People Who Inject Drugs
Katy L. Garrett, Jing-Xian Chen, Brian M. Maas, M. Cottrell +5 more
2018Journal of Pharmacology and Experimental Therapeutics26 citations Open access
Semantic Scholar
Pharmacokinetics of Two Common Antiretroviral Regimens in Older HIV-Infected Patients: A Pilot Study
Julie B. Dumond, J. Adams, Heather M. A. Prince, Racheal Kendrick +9 more
2013HIV Medicine24 citations Open access
Semantic Scholar
Models for Predicting Effective HIV Chemoprevention in Women
M. Nicol, Cindi W. Emerson, Heather M. A. Prince, J. Nelson +6 more
2015Journal of Acquired Immune Deficiency Syndromes21 citations Open access
Semantic Scholar
Predicting Effective Truvada® PrEP Dosing Strategies With a Novel PK-PD Model Incorporating Tissue Active Metabolites and Endogenous Nucleotides (EN)
M. Cottrell, Kuo H. Yang, Heather M. A. Prince, C. Sykes +9 more
201421 citations
Semantic Scholar
Next Generation 3D-Printed Intravaginal Ring for Prevention of HIV and Unintended Pregnancy
Isabella C. Young, P. Srinivasan, Roopali Shrivastava, R. Janusziewicz +14 more
2023Biomaterials20 citations Open access
Semantic Scholar
Biodegradable Polymeric Solid Implants for Ultra-Long-Acting Delivery of Single or Multiple Antiretroviral Drugs
Panita Maturavongsadit, Roopali Shrivastava, C. Sykes, M. Cottrell +3 more
2021International journal of pharmaceutics20 citations Open access
Semantic Scholar
POPULATION MODELING HIGHLIGHTS DRUG DISPOSITION DIFFERENCES BETWEEN TENOFOVIR ALAFENAMIDE AND TENOFOVIR DISOPROXIL FUMARATE IN THE BLOOD AND SEMEN
Stephen A. Greene, Jing-Xian Chen, Heather M. A. Prince, C. Sykes +6 more
2019Clinical pharmacology and therapy19 citations Open access
Semantic Scholar
Cervicovaginal and Rectal Fluid as a Surrogate Marker of Antiretroviral Tissue Concentration: Implications for Clinical Trial Design
M. Cottrell, Heather M. A. Prince, A. Allmon, K. Mollan +9 more
2016Journal of Acquired Immune Deficiency Syndromes19 citations Open access
Semantic Scholar
Application of a Scavenger Receptor A1 Targeted Polymeric Prodrug Platform for Lymphatic Drug Delivery in HIV
David M Stevens, P. Adiseshaiah, S. Dasa, Timothy M. Potter +12 more
2020Molecular Pharmaceutics18 citations Open access
Semantic Scholar
Antiretroviral Penetration across Three Preclinical Animal Models and Humans in Eight Putative HIV Viral Reservoirs
A. Devanathan, Jason R. Pirone, R. Akkina, Leila Remling‐Mulder +12 more
2019Antimicrobial Agents and Chemotherapy18 citations Open access
Semantic Scholar
Long-acting injectable multipurpose prevention technology for prevention of HIV and unplanned pregnancy
Isabella C. Young, Aryani Pallerla, M. Cottrell, Panita Maturavongsadit +8 more
2023Journal of Controlled Release17 citations Open access
Semantic Scholar
Next-generation 3D printed multipurpose prevention intravaginal ring for prevention of HIV, HSV-2, and unintended pregnancy
D. K. Dahl, Priya Srinivasan, R. Janusziewicz, Jasmine L. King +11 more
2024Journal of Controlled Release15 citations Open access
Semantic Scholar
A Novel Algorithm to Improve PrEP Adherence Monitoring Using Dried Blood Spots
A. Devanathan, Julie B. Dumond, Daijha J C Anderson, Kristen A Moody +7 more
2023Clinical pharmacology and therapy15 citations
Semantic Scholar
Antiretroviral drug exposure in lymph nodes is heterogeneous and drug dependent
E. Rosen, C. Deleage, N. White, C. Sykes +5 more
2022Journal of the International AIDS Society14 citations Open access
Semantic Scholar
Lack of viral control and development of cART escape mutations in macaques after bone marrow transplantation
C. Peterson, Kevin G. Haworth, P. Polacino, Meei-Li W. Huang +11 more
2015AIDS (London)14 citations Open access
Semantic Scholar
Next-Generation Contraceptive Intravaginal Ring: Comparison of Etonogestrel and Ethinyl Estradiol In Vitro and In Vivo Release from 3D-Printed Intravaginal Ring and NuvaRing
Isabella C. Young, Allison Thorson, M. Cottrell, C. Sykes +5 more
2024Pharmaceutics13 citations Open access
Semantic Scholar
Food insecurity is associated with lower levels of antiretroviral drug concentrations in hair among a cohort of women living with HIV in the United States.
A. Leddy, L. Sheira, Bani Tamraz, C. Sykes +12 more
2019Clinical Infectious Diseases13 citations Open access
Semantic Scholar
Depot medroxyprogesterone acetate and the vaginal microbiome as modifiers of tenofovir diphosphate and lamivudine triphosphate concentrations in the female genital tract of Ugandan women: Implications for TDF/3TC in pre-exposure prophylaxis.
M. Nicol, Prosperity Eneh, R. Nakalega, T. Kaiser +8 more
2019Clinical Infectious Diseases12 citations Open access
Semantic Scholar
The role of menopause in tenofovir diphosphate and emtricitabine triphosphate concentrations in cervical tissue
M. Nicol, Lindsey M Brewers, A. Kashuba, C. Sykes
2018AIDS (London)12 citations Open access
Semantic Scholar
Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam
Muluneh M. Fashe, T. A. Miner, J. K. Fallon, A. Schauer +3 more
2023Frontiers in Pharmacology11 citations Open access
Semantic Scholar
Differences in Local and Systemic TFV PK Among Premenopausal Versus Postmenopausal Women Exposed to TFV 1% Vaginal Gel
A. Thurman, Neelima Chandra, Nazita Yousefieh, T. Kimble +6 more
2018Journal of Acquired Immune Deficiency Syndromes11 citations Open access
Semantic Scholar
Multimodal Analysis of Drug Transporter Expression in Gastrointestinal Tissue
Corbin G. Thompson, J. K. Fallon, M. Mathews, Paige Charlins +11 more
2017AIDS (London)11 citations Open access
Semantic Scholar
Antiretroviral Penetration and Drug Transporter Concentrations in the Spleens of Three Preclinical Animal Models and Humans
A. Devanathan, J. K. Fallon, N. White, A. Schauer +12 more
2020Antimicrobial Agents and Chemotherapy9 citations Open access
Semantic Scholar
DIFFERENTIAL EXTRACELLULAR, BUT SIMILAR INTRACELLULAR, DISPOSITION OF TWO TENOFOVIR FORMULATIONS IN THE MALE GENITAL TRACT
Julie B. Dumond, S. Greene, Heather M. A. Prince, Jing-Xian Chen +8 more
2019Antiviral Therapy9 citations Open access
Semantic Scholar
Development and validation of an LC-MS/MS assay for the quantification of dolutegravir extracted from human hair
C. Sykes, Kimberly Blake, N. White, A. Schauer +4 more
2018Analytical and Bioanalytical Chemistry9 citations Open access
Semantic Scholar
Population Pharmacokinetic Model of Vaginal Tenofovir 1% Gel in the Cervicovaginal Fluid
Kuo H. Yang, Jill L. Schwartz, C. Sykes, G. Doncel +1 more
20148 citations
Semantic Scholar
Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV
A. Lisco, Camille Lange, M. Manion, Safia Kuriakose +17 more
2023Nature Medicine7 citations Open access
Semantic Scholar

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A. Kashuba×28
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A. Kashuba — researcher profile on SciRah
A. Schauer×21
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A. Schauer — researcher profile on SciRah
M. Cottrell×18
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M. Cottrell — researcher profile on SciRah
Heather M. A. Prince×13
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Heather M. A. Prince — researcher profile on SciRah

×12

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A. Kashuba — researcher profile on SciRah

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N. White — researcher profile on SciRah

M. Kovárová×9

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M. Kovárová — researcher profile on SciRah

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E. Rosen — researcher profile on SciRah

S. R. Benhabbour×8

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S. R. Benhabbour — researcher profile on SciRah

Lourdes Adamson×8

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Lourdes Adamson — researcher profile on SciRah

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K. Patterson — researcher profile on SciRah