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T. Seyfried · SciRah

Researcher profile · Semantic Scholar

T. Seyfried

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T. Seyfried — researcher profile on SciRah

h-index: 63
Works: 292
Citations: 13K

Most-cited papers

Meal frequency and timing in health and disease
M. Mattson, D. Allison, L. Fontana, M. Harvie +9 more
2014Proceedings of the National Academy of Sciences of the United States of America509 citations Open access
Semantic Scholar
Cancer as a mitochondrial metabolic disease
T. Seyfried
2015Front. Cell Dev. Biol.191 citations Open access
Semantic Scholar
Metabolic therapy: a new paradigm for managing malignant brain cancer.
T. Seyfried, Roberto E. Flores, Angela Poff, D. D'Agostino +1 more
2015Cancer Letters166 citations
Semantic Scholar
Out of Warburg effect: An effective cancer treatment targeting the tumor specific metabolism and dysregulated pH.
L. Schwartz, T. Seyfried, K. Alfarouk, Jorgelindo da Veiga Moreira +1 more
2017Seminars in Cancer Biology129 citations
Semantic Scholar
Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma
P. Mukherjee, Zachary M. Augur, Ming-Yi Li, Collin Hill +9 more
2019Communications Biology123 citations Open access
Semantic Scholar
Effects of Ketogenic metabolic therapy on patients with breast cancer: A randomized controlled clinical trial.
Adeleh Khodabakhshi, M. Akbari, H. Mirzaei, T. Seyfried +2 more
2020Clinical Nutrition122 citations
Semantic Scholar
On the Origin of ATP Synthesis in Cancer
T. Seyfried, G. Arismendi-Morillo, P. Mukherjee, C. Chinopoulos
2020iScience115 citations Open access
Semantic Scholar
Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis
C. Chinopoulos, T. Seyfried
2018ASN Neuro113 citations Open access
Semantic Scholar
The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer
Joshua J. Meidenbauer, P. Mukherjee, T. Seyfried
2015Nutrition and Metabolism101 citations Open access
Semantic Scholar
Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease
T. Seyfried, H. Choi, A. Chevalier, Daniel Hogan +2 more
2018ASN Neuro96 citations Open access
Semantic Scholar
Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up
A. Elsakka, M. A. Bary, Eman Abdelzaher, M. Elnaggar +3 more
2018Frontiers in Nutrition84 citations Open access
Semantic Scholar
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer
T. Seyfried, George W. Yu, J. Maroon, D. D'Agostino
2017Nutrition and Metabolism80 citations Open access
Semantic Scholar
Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy
Angela Poff, Nathan P. Ward, T. Seyfried, Patrick Arnold +1 more
2015PLoS ONE80 citations Open access
Semantic Scholar
Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer
M. Iyikesici, Abdul Kadir Slocum, A. Slocum, F. B. Berkarda +2 more
2017Cureus65 citations Open access
Semantic Scholar
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
T. Duraj, Miriam Kalamian, G. Zuccoli, J. Maroon +45 more
2024BMC Medicine63 citations Open access
Semantic Scholar
Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses
Zeynep Akgoc, M. Sena-Esteves, Douglas R. Martin, Xian-Lin Han +2 more
2015Journal of Lipid Research63 citations Open access
Semantic Scholar
AAV-Mediated Gene Delivery in a Feline Model of Sandhoff Disease Corrects Lysosomal Storage in the Central Nervous System
Hannah E. Rockwell, Victoria J. McCurdy, Samuel C. Eaton, Diane U. Wilson +10 more
2015ASN Neuro56 citations Open access
Semantic Scholar
Environmental stimuli shape microglial plasticity in glioma
S. Garofalo, A. Porzia, F. Mainiero, S. Di Angelantonio +17 more
2017eLife52 citations Open access
Semantic Scholar
Can the Mitochondrial Metabolic Theory Explain Better the Origin and Management of Cancer than Can the Somatic Mutation Theory?
T. Seyfried, C. Chinopoulos
2021Metabolites47 citations Open access
Semantic Scholar
Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?
T. Seyfried, Laura M. Shelton, G. Arismendi-Morillo, Miriam Kalamian +3 more
2019Neurochemical Research47 citations
Semantic Scholar
Ultrastructural characterization of the Mitochondria-associated membranes abnormalities in human astrocytomas: Functional and therapeutics implications
G. Arismendi-Morillo, A. Castellano-Ramírez, T. Seyfried
2017Ultrastructural Pathology43 citations
Semantic Scholar
Caprylic (Octanoic) Acid as a Potential Fatty Acid Chemotherapeutic for Glioblastoma.
M. Altinoz, A. Ozpinar, T. Seyfried
2020Prostaglandins, Leukotrienes and Essential Fatty Acids42 citations
Semantic Scholar
Consideration of Ketogenic Metabolic Therapy as a Complementary or Alternative Approach for Managing Breast Cancer
T. Seyfried, P. Mukherjee, M. Iyikesici, Abdul Kadir Slocum +3 more
2020Frontiers in Nutrition41 citations Open access
Semantic Scholar
The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer
T. Seyfried, Derek C. Lee, T. Duraj, N. Ta +4 more
2025Journal of Bioenergetics and Biomembranes40 citations
Semantic Scholar
Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report
T. Seyfried, A. Shivane, Miriam Kalamian, J. Maroon +2 more
2021Frontiers in Nutrition36 citations Open access
Semantic Scholar
Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson’s Disease
J. Schneider, T. Seyfried, Hyo-S. Choi, Sarah K. Kidd
2015PLoS ONE36 citations Open access
Semantic Scholar
The role of metabolic therapy in treating glioblastoma multiforme
J. Maroon, T. Seyfried, J. P. Donohue, J. Bost
2015Surgical neurology international34 citations Open access
Semantic Scholar
Metabolic management of microenvironment acidity in glioblastoma
T. Seyfried, G. Arismendi-Morillo, G. Zuccoli, Derek Lee +9 more
2022Frontiers in Oncology32 citations Open access
Semantic Scholar
Proline Oxidation Supports Mitochondrial ATP Production When Complex I Is Inhibited
G. Pallag, Sara Nazarian, Dora Ravasz, D. Bui +5 more
2022International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
Metabolic therapy and bioenergetic analysis: The missing piece of the puzzle
T. Duraj, Josefa Carrión-Navarro, T. Seyfried, Noemí García-Romero +1 more
2021Molecular Metabolism31 citations Open access
Semantic Scholar
Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma: a clinical study
A. Kiryttopoulos, Athanasios E. Evangeliou, Irene Katsanika, I. Boukovinas +8 more
2025Frontiers in Nutrition28 citations Open access
Semantic Scholar
Mycoplasma infection and hypoxia initiate succinate accumulation and release in the VM-M3 cancer cells.
Roberto E. Flores, Ashley K. Brown, Luke J. Taus, Julianna Khoury +9 more
2018Biochimica et Biophysica Acta - Bioenergetics28 citations Open access
Semantic Scholar
Gene expression in the epileptic (EL) mouse hippocampus.
Tih-Shih Lee, Alexander Y. Li, A. Rapuano, J. Mantis +3 more
2020Neurobiology of Disease27 citations Open access
Semantic Scholar
lmmunocytochemical Localization of G m Ganglioside to Astrocytes in Murine Cerebellar Mutants
S. LeVine, T. Seyfried, YU ROBERTK., J. Goldman
201825 citations
Semantic Scholar
Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells
Derek C. Lee, Linh Ta, P. Mukherjee, T. Duraj +7 more
2024bioRxiv23 citations Open access
Semantic Scholar
Personalized Nutrition in Disrupting Cancer — Proceedings From the 2017 American College of Nutrition Annual Meeting
T. Wallace, S. Bultman, C. D'Adamo, C. Daniel +8 more
2018Journal of the American College of Nutrition23 citations Open access
Semantic Scholar
Influence of Serum and Hypoxia on Incorporation of [14C]-d-Glucose or [14C]-l-Glutamine into Lipids and Lactate in Murine Glioblastoma Cells
N. Ta, T. Seyfried
2015Lipids22 citations
Semantic Scholar
Ketosis Suppression and Ageing (KetoSAge): The Effects of Suppressing Ketosis in Long Term Keto-Adapted Non-Athletic Females
Isabella D. Cooper, Yvoni Kyriakidou, Kurtis Edwards, Lucy Petagine +10 more
2023International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
Bis(monoacylglycero)phosphate as a Macrophage Enriched Phospholipid
Zeynep Akgoc, Sonia Iosim, T. Seyfried
2015Lipids20 citations
Semantic Scholar
Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics
Judit Doczi, Noemi Karnok, D. Bui, V. Azarov +5 more
2022bioRxiv18 citations Open access
Semantic Scholar
Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration
Jean-Pyo Lee, Runquan Zhang, Maocai Yan, S. Duggineni +17 more
2020Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia
Dora Ravasz, D. Bui, Sara Nazarian, G. Pallag +19 more
2024Scientific Reports16 citations Open access
Semantic Scholar
Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals
Yanyu Jiang, Xi Yang, Chang-Sheng Dong, Yun Lu +28 more
2021Clinical and Translational Medicine15 citations Open access
Semantic Scholar
Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis.
A. Gross, H. Gray-Edwards, Cassie N Bebout, N. Ta +9 more
2021Brain : a journal of neurology15 citations Open access
Semantic Scholar
Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma
Zachary M. Augur, Catherine M. Doyle, Ming-Yi Li, P. Mukherjee +1 more
2018Frontiers in Nutrition15 citations Open access
Semantic Scholar
Need for new review of article on ketogenic dietary regimes for cancer patients
R. Klement, R. Feinman, Elena C. Gross, C. Champ +7 more
2017Medical Oncology13 citations
Semantic Scholar
Restricted Ketogenic Diet Therapy for Primary Lung Cancer With Metastasis to the Brain: A Case Report
A. Evangeliou, M. Spilioti, Despoina Vassilakou, F. Goutsaridou +1 more
2022Cureus10 citations Open access
Semantic Scholar
Could Cytoplasmic Lipid Droplets be Linked to Inefficient Oxidative Phosphorylation in Cancer?
T. Seyfried, N. Ta, T. Duraj, Derek C. Lee +3 more
2024Current Tissue Microenvironment Reports9 citations
Semantic Scholar
Metabolically Supported Chemotherapy for Managing End-Stage Breast Cancer: A Complete and Durable Response
M. Iyikesici, Abdul Kadir Slocum, Nasha Winters, Miriam Kalamian +1 more
2021Cureus9 citations Open access
Semantic Scholar
Myelin Abnormalities in the Optic and Sciatic Nerves in Mice With GM1-Gangliosidosis
Karie A. Heinecke, Adrienne M. Luoma, A. d'Azzo, D. Kirschner +1 more
2015ASN Neuro9 citations Open access
Semantic Scholar

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