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O. Demin · SciRah

Researcher profile · Semantic Scholar

O. Demin

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O. Demin — researcher profile on SciRah

h-index: 7
Works: 29
Citations: 149

Most-cited papers

Integration not isolation: arguing the case for quantitative and systems pharmacology in drug discovery and development.
B. Agoram, O. Demin
2011Drug Discovery Today42 citations
Semantic Scholar
A mathematical model of multisite phosphorylation of tau protein
A. Stepanov, T. Karelina, N. Markevich, O. Demin +1 more
2018PLoS ONE23 citations Open access
Semantic Scholar
Analysis of the efficacy of SGLT2 inhibitors using semi-mechanistic model
O. Demin, T. Yakovleva, Dmitry Kolobkov
2014Frontiers in Pharmacology14 citations Open access
Semantic Scholar
Kinetic modeling as a tool to integrate multilevel dynamic experimental data.
E. Mogilevskaya, N. Bagrova, T. Plyusnina, N. Gizzatkulov +9 more
2009Methods in molecular biology14 citations
Semantic Scholar
Studying the Progression of Amyloid Pathology and Its Therapy Using Translational Longitudinal Model of Accumulation and Distribution of Amyloid Beta
T. Karelina, O. Demin, S. Duvvuri, T. Nicholas
2017CPT: Pharmacometrics & Systems Pharmacology12 citations Open access
Semantic Scholar
A Translational Systems Pharmacology Model for Aβ Kinetics in Mouse, Monkey, and Human
T. Karelina, O. Demin, T. Nicholas, Ya-Song Lu +2 more
2017CPT: Pharmacometrics & Systems Pharmacology10 citations Open access
Semantic Scholar
Application of different approaches to generate virtual patient populations for the quantitative systems pharmacology model of erythropoiesis
G. Kolesova, A. Stepanov, G. Lebedeva, O. Demin
2022Journal of Pharmacokinetics and Pharmacodynamics7 citations Open access
Semantic Scholar
Monoclonal antibody therapy efficacy can be boosted by combinations with other treatments: Predictions using an integrated Alzheimer’s Disease Platform
T. Karelina, S. Lerner, A. Stepanov, Mark Meerson +1 more
2021CPT: Pharmacometrics & Systems Pharmacology7 citations Open access
Semantic Scholar
CYTOCON: The manually curated database of human in vivo cell and molecule concentrations
V. Leonov, E. Mogilevskaya, Elita Gerasimuk, N. Gizzatkulov +1 more
2022CPT: Pharmacometrics & Systems Pharmacology6 citations Open access
Semantic Scholar
Correction: A mathematical model of multisite phosphorylation of tau protein
A. Stepanov, T. Karelina, N. Markevich, O. Demin +1 more
2018PLoS ONE6 citations Open access
Semantic Scholar
Abstract 2233: Prediction and comparison of PD-1 receptor occupancy in the tumor after treatment with immune checkpoint inhibitors
Dmitry Shchelokov, O. Demin
2020Immunology4 citations
Semantic Scholar
Abstract 5421: Prediction of intratumoral TIGIT receptor occupancy after the treatment with anti-TIGIT antibodies
Dmitry Shchelokov, O. Demin, Ahsan Rizwan, Yun Zhang +3 more
2022Cancer Research2 citations
Semantic Scholar
A Quantitative Systems Pharmacology (QSP) Model to Predict Receptor Occupancy of Bruton's Tyrosine Kinase (BTK) Inhibitors in Peripheral Blood Mononuclear Cells, Bone Marrow and Lymph Nodes of Patients with B-Cell Malignancies
S. Sahasranaman, O. Demin, Dmitry Shchelokov, V. Musatova +2 more
2019Blood1 citations
Semantic Scholar
P1‐296: An updated Aβ systems kinetic model for mouse, monkey and human
Ya-Song Lu, H. Barton, T. Nicholas, S. Duvvuri +4 more
20121 citations
Semantic Scholar
Abstract 2951: NI-2901, an affinity-optimized CD47xPD-L1 bispecific antibody for dual immune checkpoint blockade
X. Chauchet, Sébastien Calloud, Pauline Lloveras, Nicolas Bosson +19 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 5049: Prediction of pharmacokinetics and receptor occupancy of a bispecific antibody against CD40 and PD-L1
A. Diakonova, O. Demin, Dmitry Shchelokov
2022Cancer Research0 citations
Semantic Scholar
481 An affinity-optimized CD47xPD-L1 bispecific antibody for dual immune checkpoint blockade
X. Chauchet, Sébastien Calloud, M. Legrand, Laura Cons +16 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
1019P Selection of the optimal dose for ALX148, a CD47 blocker, using pharmacokinetic/pharmacodynamic modeling
O. Demin, E. Vasileva
2021Annals of Oncology0 citations Open access
Semantic Scholar
Abstract 5488: Prediction of target receptor occupancy for ALX148, a CD47 blocker, using mechanistic PK/RO modeling
E. Vasileva, O. Demin
2020Clinical research0 citations
Semantic Scholar
Abstract 687: Implementation of inter-patient variability in semi-mechanistic model of melanoma treatment with vemurafenib
Dmitry Shchelokov, O. Demin
2019Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
Abstract 679: Quantitative systems pharmacology modeling of immunotherapies in B-cell acute lymphoblastic leukemia
O. Demin, A. Nikitich
2019Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
Model-based analysis of clinical assays for assessing the efficacy of vaccines against Respiratory Syncytial Virus (RSV)
G. Lebedeva, N. Pakhomov, O. Demin
20170 citations
Semantic Scholar
Mechanistic Modeling of Co-stimulatory and Co-inhibitory Surface Molecules Effect on Cell-to-cell Interactions
O. Demin
20170 citations
Semantic Scholar
Quantitive Systems Pharmacology Model of Hepatitis C: Prediction of Results of Ongoing Clinical Trials of Direct Antivaral Agents Combination Therapies
O. Demin
20160 citations
Semantic Scholar
Systems Pharmacology Modeling of Acute Lymphoblastic Leukemia Progression and Treatment.
A. Nikitich, O. Demin
20150 citations
Semantic Scholar
Poster Walk I
A. Oganesian, O. Demin, A. Nikitich, M. +9 more
2015Clinical Pharmacology & Therapeutics0 citations
Semantic Scholar
Towards Modeling of Metabolic Syndrome: Tissue Crosstalk in Lipid Spillover
Sergey Smirnov, E. Metelkin, N. Gizzatkulov, O. Stepanov +1 more
20140 citations
Semantic Scholar
P1‐247: Beta‐amyloid aggregation human systems pharmacology modeling: Development and application to pharmacological targets in Alzheimer's disease
T. Nicholas, H. Barton, Ya-Song Lu, S. Duvvuri +4 more
20120 citations Open access
Semantic Scholar
European Communications in Mathematical and Theoretical Biology February 2008 , No . 10 E MTB Communications
W. Alt, H. Byrne, A. Deutsch, L. Preziosi +3 more
20080 citations
Semantic Scholar

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