Researcher profile · Semantic Scholar

T. Schlake

h-index: 27
Works: 40
Citations: 3,447

Most-cited papers

Developing mRNA-vaccine technologies
T. Schlake, A. Thess, M. Fotin‐Mleczek, K. Kallen
2012RNA Biology540 citations Open access
Semantic Scholar
Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
A. Thess, S. Grund, B. Mui, Michael J. Hope +3 more
2015Molecular Therapy475 citations Open access
Semantic Scholar
Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection
B. Petsch, Margit Schnee, Annette B. Vogel, E. Lange +7 more
2012Nature Biotechnology441 citations
Semantic Scholar
Igf-I signalling controls the hair growth cycle and the differentiation of hair shafts.
Nicole Weger, T. Schlake
2005Journal of Investigative Dermatology183 citations Open access
Semantic Scholar
A novel, disruptive vaccination technology
K. Kallen, R. Heidenreich, Margit Schnee, B. Petsch +6 more
2013Human Vaccines & Immunotherapeutics177 citations Open access
Semantic Scholar
mRNA mediates passive vaccination against infectious agents, toxins, and tumors
Moritz Thran, J. Mukherjee, M. Pönisch, K. Fiedler +9 more
2017EMBO Molecular Medicine151 citations Open access
Semantic Scholar
Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway
C. Lorenz, M. Fotin‐Mleczek, G. Roth, Christina Becker +5 more
2011RNA Biology149 citations Open access
Semantic Scholar
Determination of hair structure and shape.
T. Schlake
2007Seminars in Cell and Developmental Biology125 citations
Semantic Scholar
Scaffold/matrix-attached regions: structural properties creating transcriptionally active loci.
J. Bode, T. Schlake, M. RÍOS-RAMÍREZ, C. Mielke +3 more
1995International Review of Cytology115 citations
Semantic Scholar
mRNA as novel technology for passive immunotherapy
T. Schlake, A. Thess, Moritz Thran, Ingo Jordan
2018Cellular and Molecular Life Sciences112 citations Open access
Semantic Scholar
The nude gene encodes a sequence-specific DNA binding protein with homologs in organisms that lack an anticipatory immune system.
T. Schlake, M. Schorpp, Michael Nehls, Thomas Boehm
1997Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
Semantic Scholar
The Transgeneticists Toolbox: Novel Methods for the Targeted Modification of Eukaryotic Genomes
J. Bode, T. Schlake, Michael Iber, D. Schübeler +3 more
2000Biological chemistry88 citations
Semantic Scholar
mRNA: A Novel Avenue to Antibody Therapy?
T. Schlake, Moritz Thran, K. Fiedler, R. Heidenreich +2 more
2019Molecular Therapy81 citations Open access
Semantic Scholar
Forkhead/winged‐helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of the Nude skin phenotype
T. Schlake, M. Schorpp, A. Maul‐Pavicic, A. Malashenko +1 more
2000Developmental Dynamics75 citations Open access
Semantic Scholar
FGF signals specifically regulate the structure of hair shaft medulla via IGF-binding protein 5
T. Schlake
2005Development54 citations
Semantic Scholar
Gene expression within a chromatin domain: the role of core histone hyperacetylation.
T. Schlake, D. Klehr-Wirth, M. Yoshida, T. Beppu +1 more
1994Biochemistry52 citations
Semantic Scholar
RNActive® Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines.
S. Rauch, J. Lutz, Aleksandra Kowalczyk, T. Schlake +1 more
2017Methods in molecular biology47 citations
Semantic Scholar
A plant scaffold attached region detected close to a T-DNA integration site is active in mammalian cells.
A. Dietz, Volker Kay, T. Schlake, J. Landsmann +1 more
1994Nucleic Acids Research42 citations Open access
Semantic Scholar
Segmental Igfbp5 expression is specifically associated with the bent structure of zigzag hairs.
T. Schlake
2005Mechanisms of Development40 citations Open access
Semantic Scholar
The nude gene and the skin
T. Schlake
2001Experimental Dermatology40 citations Open access
Semantic Scholar
Localization of Shh expression by Wnt and Eda affects axial polarity and shape of hairs.
Brigitte Hammerschmidt, T. Schlake
2007Developmental Biology38 citations Open access
Semantic Scholar
Major shifts in genomic activity accompany progression through different stages of the hair cycle.
T. Schlake, M. Beibel, Nicole Weger, T. Boehm
2004Gene Expression Patterns33 citations
Semantic Scholar
Igfbp3 modulates cell proliferation in the hair follicle.
Nicole Weger, T. Schlake
2005Journal of Investigative Dermatology30 citations Open access
Semantic Scholar
Canonical WNT Signalling Controls Hair Follicle Spacing
T. Schlake, Stefanie Sick
2007Cell Adhesion & Migration29 citations Open access
Semantic Scholar
mRNA as a Novel Treatment Strategy for Hereditary Spastic Paraplegia Type 5
S. Hauser, Marion Poenisch, Yvonne Schelling, Philip Höflinger +10 more
2019Molecular Therapy: Methods & Clinical Development28 citations Open access
Semantic Scholar
Genetically separable determinants of hair keratin gene expression
M. Schorpp, T. Schlake, Darren Kreamalmeyer, P. Allen +1 more
2000Developmental Dynamics28 citations Open access
Semantic Scholar
Genetic dissection of thymus development.
M. Schorpp, W. Wiest, C. Egger, M. Hammerschmidt +2 more
2000Current Topics in Microbiology and Immunology27 citations
Semantic Scholar
Formation of regulator/target gene relationships during evolution.
T. Schlake, M. Schorpp, Thomas Boehm
2000Gene26 citations
Semantic Scholar
Krox20, a novel candidate for the regulatory hierarchy that controls hair shaft bending.
T. Schlake
2006Mechanisms of Development23 citations Open access
Semantic Scholar
Expression domains in the skin of genes affected by the nude mutation and identified by gene expression profiling.
T. Schlake, T. Boehm
2001Mechanisms of Development21 citations Open access
Semantic Scholar
A yeast artificial chromosome contig spanning the mouse immunoglobulin kappa light chain locus
I. Schupp, T. Schlake, T. Kirschbaum, H. Zachau +1 more
1997Immunogenetics21 citations
Semantic Scholar
Transposon-induced splicing defect in the rat nude gene
M. Huth, T. Schlake, T. Boehm
1997Immunogenetics19 citations
Semantic Scholar
Mating configurations in Schizosaccharomyces pombe strains of different geographical origins
T. Schlake, H. Gutz
1993Current Genetics10 citations
Semantic Scholar
Messenger RNA Vaccines
J. Probst, M. Fotin‐Mleczek, T. Schlake, A. Thess +2 more
20128 citations
Semantic Scholar
Predetermined chromosomal deletion encompassing the Nf-1 gene
T. Schlake, I. Schupp, K. Kutsche, A. Mincheva +2 more
1999Oncogene8 citations Open access
Semantic Scholar
Response to Ben Amitai et al.
T. Schlake
20065 citations Open access
Semantic Scholar
Sequence-Optimized mRNA Vaccines Against Infectious Disease.
S. Rauch, J. Lutz, Janine Mühe, Aleksandra Kowalczyk +2 more
2024Methods in molecular biology2 citations
Semantic Scholar
Design options for mRNA-encoded BoNT Antitoxins employing camelid single-domain antibody (VHH) components
C. Shoemaker, K. Lam, Moritz Thran, T. Schlake +3 more
2018Toxicon1 citations
Semantic Scholar
Nucleic acids encoding crispr-associated proteins and uses thereof
Fréderic Chevessier-Tuennesen, Marion Poenisch, T. Schlake
20180 citations
Semantic Scholar
nucleic acid comprising or encoding a stem-loop sequence and histone poly (A) or a polyadenylation signal to increase expression of an encoded protein
A. Thess, T. Schlake, J. Probst
20110 citations
Semantic Scholar

M. Schorpp

×5

K. Kallen×4

Moritz Thran×4

B. Petsch×3

Nicole Weger×3

J. Probst×3

B. Mui×2

Patrick Baumhof×2