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Baptiste Legrand · SciRah

Researcher profile · Semantic Scholar

Baptiste Legrand

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Baptiste Legrand — researcher profile on SciRah

h-index: 17
Works: 67
Citations: 832

Most-cited papers

Helical oligomers of thiazole-based γ-amino acids: synthesis and structural studies.
L. Mathieu, Baptiste Legrand, Cheng-Hua Deng, Lubomir L. Vezenkov +8 more
2013Angewandte Chemie55 citations
Semantic Scholar
Sol–gel synthesis of collagen-inspired peptide hydrogel
C. Echalier, S. Jebors, G. Laconde, Luc Brunel +10 more
201741 citations Open access
Semantic Scholar
Thiazole-based γ-building blocks as reverse-turn mimetic to design a gramicidin S analogue: conformational and biological evaluation.
Baptiste Legrand, L. Mathieu, A. Lebrun, Soahary Andriamanarivo +6 more
2014Chemistry39 citations
Semantic Scholar
A Two-amino Acid Mutation Encountered in Duchenne Muscular Dystrophy Decreases Stability of the Rod Domain 23 (R23) Spectrin-like Repeat of Dystrophin*
Sébastien Legardinier, Baptiste Legrand, C. Raguénès-Nicol, A. Bondon +4 more
2009Journal of Biological Chemistry38 citations Open access
Semantic Scholar
(S)-ABOC: a rigid bicyclic β-amino acid as turn inducer.
C. André, Baptiste Legrand, Cheng-Hua Deng, C. Didierjean +5 more
2012Organic Letters35 citations
Semantic Scholar
Structure and mechanism of action of a de novo antimicrobial detergent-like peptide.
Baptiste Legrand, M. Laurencin, J. Sarkis, Emilie Duval +8 more
2011Biochimica et Biophysica Acta35 citations Open access
Semantic Scholar
Spectrin-like Repeats 11–15 of Human Dystrophin Show Adaptations to a Lipidic Environment*
J. Sarkis, J. Hubert, Baptiste Legrand, Estelle Robert +5 more
2011Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Computational Study of the Human Dystrophin Repeats: Interaction Properties and Molecular Dynamics
Baptiste Legrand, Emmanuel Giudice, Aurélie Nicolas, O. Delalande +1 more
2011PLoS ONE31 citations Open access
Semantic Scholar
Assessment of ecosystem services and natural capital dynamics in agroecosystems
Manon Dardonville, Baptiste Legrand, H. Clivot, C. Bernardin +2 more
2022Ecosystem Services28 citations Open access
Semantic Scholar
Silaproline helical mimetics selectively form an all-trans PPII helix.
C. Martin, Baptiste Legrand, A. Lebrun, D. Berthomieu +2 more
2014Chemistry28 citations
Semantic Scholar
From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity.
M. Laurencin, Baptiste Legrand, Emilie Duval, J. Henry +3 more
2012Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Unprecedented chain-length-dependent conformational conversion between 11/9 and 18/16 helix in α/β-hybrid peptides.
Baptiste Legrand, C. André, Laure Moulat, E. Wenger +6 more
2014Angewandte Chemie27 citations
Semantic Scholar
Helical γ-peptide foldamers as dual inhibitors of amyloid-β peptide and islet amyloid polypeptide oligomerization and fibrillization.
S. Ongeri, J. Kaffy, Corentin Berardet, L. Mathieu +5 more
2020Chemistry25 citations Open access
Semantic Scholar
Stapled peptide targeting the CDK4/Cyclin D interface combined with Abemaciclib inhibits KRAS mutant lung cancer growth
C. Bouclier, Matthieu Simon, G. Laconde, M. Pellerano +11 more
2020Theranostics20 citations Open access
Semantic Scholar
Robust helix formation in a new family of oligoureas based on a constrained bicyclic building block.
Baptiste Legrand, C. André, E. Wenger, C. Didierjean +4 more
2012Angewandte Chemie20 citations
Semantic Scholar
Cyclic Enkephalins with a Diversely Substituted Guanidine Bridge or a Thiourea Bridge: Synthesis, Biological and Structural Evaluations
Youness Touati-Jallabe, Engin Bojnik, Baptiste Legrand, Elodie Mauchauffée +6 more
2013Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Prospect of Thiazole-based γ-Peptide Foldamers in Enamine Catalysis: Exploration of the Nitro-Michael Addition.
Julie Aguesseau-Kondrotas, Matthieu Simon, Baptiste Legrand, J. Bantignies +6 more
2019Chemistry18 citations
Semantic Scholar
Catalytic Foldamers: When the Structure Guides the Function
Baptiste Legrand, Julie Aguesseau-Kondrotas, Matthieu Simon, L. Maillard
2020Catalysts17 citations Open access
Semantic Scholar
Tailoring the Physicochemical Properties of Antimicrobial Peptides onto Thiazole-based γ-Peptide Foldamer.
C. Bonnel, Baptiste Legrand, Matthieu Simon, M. Clavié +6 more
2020Journal of Medicinal Chemistry16 citations
Semantic Scholar
How are 1,2,3-triazoles accommodated in helical secondary structures?
Khoubaib Ben Haj Salah, Sanjita Das, Nicolas Ruiz, V. Andreu +6 more
2018Organic and biomolecular chemistry16 citations
Semantic Scholar
LEON-BIS: multiple alignment evaluation of sequence neighbours using a Bayesian inference system
Renaud Vanhoutrève, Arnaud Kress, Baptiste Legrand, H. Gass +2 more
2016BMC Bioinformatics15 citations Open access
Semantic Scholar
Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction.
Vincent Martin, Baptiste Legrand, Lubomir L. Vezenkov, Mathéo Berthet +5 more
2015Angewandte Chemie14 citations
Semantic Scholar
Straightforward strategy to substitute amide bonds by 1,2,3‐triazoles in peptaibols analogs using Aibψ[Tz]‐Xaa dipeptides
Khoubaib Ben Haj Salah, Baptiste Legrand, Sanjita Das, Jean Martínez +1 more
2015Biopolymers14 citations
Semantic Scholar
C9/12 Ribbon-Like Structures in Hybrid Peptides Alternating α- and Thiazole-Based γ-Amino Acids.
C. Bonnel, Baptiste Legrand, Matthieu Simon, Jean Martínez +6 more
2017Chemistry13 citations
Semantic Scholar
Enhancing the Antimicrobial Activity of Alamethicin F50/5 by Incorporating N-terminal Hydrophobic Triazole Substituents.
Sanjita Das, Khoubaib Ben Haj Salah, E. Wenger, Jean Martínez +8 more
2017Chemistry13 citations Open access
Semantic Scholar
α,β-Unsaturated γ-Peptide Foldamers.
Baptiste Legrand, L. Maillard
2021ChemPlusChem12 citations
Semantic Scholar
Potent Lys Patch-Containing Stapled Peptides Targeting PCSK9.
Kévin Bourbiaux, Baptiste Legrand, P. Verdié, S. Mallart +9 more
2021Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Ribbon‐like Foldamers for Cellular Uptake and Drug Delivery
Lubomir L. Vezenkov, Vincent Martin, N. Bettache, Matthieu Simon +9 more
2017ChemBioChem12 citations
Semantic Scholar
FT-IR and NMR structural markers for thiazole-based γ-peptide foldamers.
Clément Bonnel, Baptiste Legrand, Jean-Louis Bantignies, H. Petitjean +3 more
2016Organic and biomolecular chemistry12 citations
Semantic Scholar
Mixed oligoureas based on constrained bicyclic and acyclic β-amino acids derivatives: on the significance of the subunit configuration for folding.
C. André, Baptiste Legrand, Laure Moulat, E. Wenger +6 more
2013Chemistry12 citations
Semantic Scholar
Selectivity Modulation and Structure of α/aza-β3 Cyclic Antimicrobial Peptides.
M. Laurencin, Matthieu Simon, Y. Fleury, M. Baudy-Floc’h +2 more
2018Chemistry11 citations
Semantic Scholar
Gelatin modified with alkoxysilanes (GelmSi) forms hybrid hydrogels for bioengineering applications.
Matthieu Simon, M. Maumus, Baptiste Legrand, Liliane Sole +5 more
2023Biomaterials Advances10 citations Open access
Semantic Scholar
Molecular basis of the Tfs1/Ira2 interaction: a combined protein engineering and molecular modelling study.
A. Gombault, F. Godin, D. Sy, Baptiste Legrand +4 more
2007Journal of Molecular Biology10 citations
Semantic Scholar
1-Aminobicyclo[2.2.2]octane-2-carboxylic Acid and Derivatives As Chiral Constrained Bridged Scaffolds for Foldamers and Chiral Catalysts.
Pierre Milbeo, Jean Martínez, M. Amblard, M. Calmès +1 more
2021Accounts of Chemical Research9 citations Open access
Semantic Scholar
The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides
N. Kebe, K. Samanta, Priyanka Singh, Josephine Lai-Kee-Him +12 more
2019International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
A General Approach to the Aza-Diketomorpholine Scaffold.
Mathéo Berthet, Baptiste Legrand, Jean Martínez, I. Parrot
2017Organic Letters9 citations
Semantic Scholar
Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives
C. Echalier, Aleksandra Kalistratova, J. Ciccione, A. Lebrun +9 more
20169 citations
Semantic Scholar
Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination.
Benoît Gautier, Mélanie Forêt Jacquard, Sophie Guelfi, Scarlette Abbou +7 more
2022Journal of Medicinal Chemistry8 citations
Semantic Scholar
Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases.
Astrid Knuhtsen, Baptiste Legrand, O. Van der Poorten, M. Amblard +4 more
2016Chemistry8 citations
Semantic Scholar
Towards the total synthesis of trichormamide A, a cyclic undecapeptide
Michel Gaillard, Sanjit Das, Mahamadou Djibo, Delphine Raviglione +3 more
2018Tetrahedron Letters7 citations Open access
Semantic Scholar
12/14/14-Helix Formation in 2:1 α/β-Hybrid Peptides Containing Bicyclo[2.2.2]octane Ring Constraints.
Baptiste Legrand, C. André, Laure Moulat, C. Didierjean +5 more
2016Chemistry7 citations
Semantic Scholar
Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery
Matthieu Simon, Nabila Laroui, M. Heyraud, G. Laconde +7 more
2020Nanomaterials6 citations Open access
Semantic Scholar
Synthesis of [1,2,4]Triazolo[4,3- a]piperazin-6-ones: An Approach to the Triazole-Fused Ketopiperazine Scaffold.
Khoubaib Ben Haj Salah, Baptiste Legrand, Mathieu Bibian, E. Wenger +2 more
2018Organic Letters6 citations
Semantic Scholar
Indoloazepinone‐Constrained Oligomers as Cell‐Penetrating and Blood–Brain‐Barrier‐Permeating Compounds
O. Van der Poorten, Baptiste Legrand, Lubomir L. Vezenkov, J. García-Pindado +10 more
2018ChemBioChem6 citations
Semantic Scholar
The C-terminal segment of Leishmania major HslU: Toward potential inhibitors of LmHslVU activity.
Priyanka Singh, K. Samanta, N. Kebe, G. Michel +8 more
2021Bioorganic chemistry (Print)4 citations Open access
Semantic Scholar
Self-mineralization and assembly of a bis-silylated Phe–Phe pseudodipeptide to a structured bioorganic–inorganic material
S. Jebors, L. Valot, C. Echalier, Baptiste Legrand +8 more
2019Materials Horizons4 citations Open access
Semantic Scholar
Planar Chiral p,p'-Terphenyl-Based Cyclophanes with Remarkable Enantiomer Stability: Synthesis, Theoretical Investigations, and Complexation Studies.
Ioan Stroia, Mădălina Elena Moisă, Alexandra Pop, Baptiste Legrand +3 more
2023Journal of Organic Chemistry3 citations
Semantic Scholar
The Unexpected Helical Supramolecular Assembly of a Simple Achiral Acetamide Tecton Generates Selective Water Channels.
D. Dumitrescu, Jordi Rull-Barrull, Anthony R. Martin, N. Masquelez +12 more
2022Chemistry3 citations Open access
Semantic Scholar
Selectivity Modulation and Structure of alpha/aza-beta(3) Cyclic Antimicrobial Peptides
M. Laurencin, Matthieu Simon, Y. Fleury, Arnaud +2 more
20222 citations
Semantic Scholar
A bicyclic unit reversal to stabilize the 12/14-helix in mixed homochiral oligoureas.
Pierre Milbeo, Matthieu Simon, C. Didierjean, E. Wenger +5 more
2020Chemical Communications2 citations Open access
Semantic Scholar

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