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N. Sanders · SciRah

Researcher profile · Semantic Scholar

N. Sanders

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N. Sanders — researcher profile on SciRah

h-index: 57
Works: 182
Citations: 11K

Most-cited papers

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls.
Dries Vercauteren, R. Vandenbroucke, A. Jones, J. Rejman +4 more
2010Molecular Therapy684 citations Open access
Semantic Scholar
N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice.
Oliwia Andries, Séan Mc Cafferty, S. De Smedt, Ron Weiss +2 more
2015Journal of Controlled Release623 citations Open access
Semantic Scholar
Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved.
I. Lentacker, Bart Geers, J. Demeester, S. De Smedt +1 more
2010Molecular Therapy305 citations Open access
Semantic Scholar
mRNA as gene therapeutic: how to control protein expression.
G. Tavernier, Oliwia Andries, J. Demeester, N. Sanders +2 more
2011Journal of Controlled Release242 citations
Semantic Scholar
Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design.
K. Buyens, S. De Smedt, K. Braeckmans, J. Demeester +8 more
2012Journal of Controlled Release195 citations
Semantic Scholar
Self-assembled liposome-loaded microbubbles: The missing link for safe and efficient ultrasound triggered drug-delivery.
Bart Geers, I. Lentacker, N. Sanders, J. Demeester +2 more
2011Journal of Controlled Release172 citations Open access
Semantic Scholar
Recent progress in West Nile virus diagnosis and vaccination
M. de Filette, S. Ulbert, M. Diamond, N. Sanders
2012Veterinary Research159 citations Open access
Semantic Scholar
Nanoparticle‐Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses
Lutz Nuhn, S. De Koker, S. Van Lint, Zifu Zhong +10 more
2018Advances in Materials139 citations
Semantic Scholar
Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across
An-Katrien Minnaert, Helena Vanluchene, Rein Verbeke, I. Lentacker +4 more
2021Advanced Drug Delivery Reviews132 citations Open access
Semantic Scholar
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis
Katrien Van Impe, Jonas Bethuyne, Steven K. Cool, F. Impens +14 more
2013Breast Cancer Research110 citations Open access
Semantic Scholar
Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses.
A. De Beuckelaer, C. Pollard, S. Van Lint, K. Roose +11 more
2016Molecular Therapy106 citations Open access
Semantic Scholar
mRNA therapeutics deliver a hopeful message
Zifu Zhong, Séan Mc Cafferty, F. Combes, H. Huysmans +5 more
2018Nano Today105 citations
Semantic Scholar
Lipid-mediated gene delivery to the skin.
Barbara Geusens, Tine Strobbe, S. Bracke, P. Dynoodt +3 more
2011European Journal of Pharmaceutical Sciences103 citations
Semantic Scholar
Immune cells as tumor drug delivery vehicles.
F. Combes, E. Meyer, N. Sanders
2020Journal of Controlled Release83 citations Open access
Semantic Scholar
Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin
H. Huysmans, Zifu Zhong, Joyca De Temmerman, B. Mui +5 more
2019Molecular Therapy: Nucleic Acids78 citations Open access
Semantic Scholar
Potent and Prolonged innate immune activation by enzyme-sensitive imidazoquinoline TLR7/8 agonist prodrug vesicles
Bi Wang, S. Van Herck, Yong Chen, Xiangyang Bai +11 more
2020Journal of the American Chemical Society72 citations Open access
Semantic Scholar
Chlamydial Infection From Outside to Inside
Arlieke Gitsels, N. Sanders, D. Vanrompay
2019Frontiers in Microbiology70 citations Open access
Semantic Scholar
Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer
Jonas Steenbrugge, Koen Breyne, K. Demeyere, O. De Wever +6 more
2018Journal of experimental & clinical cancer research : CR68 citations Open access
Semantic Scholar
Small-molecule-based regulation of RNA-delivered circuits in mammalian cells
Tyler E. Wagner, Jacob R. Becraft, Katie Bodner, Brian Teague +11 more
2018Nature Chemical Biology67 citations
Semantic Scholar
Coupling of drug containing liposomes to microbubbles improves ultrasound triggered drug delivery in mice.
Steven K. Cool, Bart Geers, S. Roels, S. Stremersch +5 more
2013Journal of Controlled Release63 citations
Semantic Scholar
Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine
S. Jangra, J. D. de Vrieze, Angela Choi, Raveen Rathnasinghe +18 more
2021Angewandte Chemie62 citations Open access
Semantic Scholar
Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine
Zifu Zhong, João Paulo Portela Catani, Séan Mc Cafferty, L. Couck +9 more
2019Vaccines61 citations Open access
Semantic Scholar
Innate immune response and programmed cell death following carrier-mediated delivery of unmodified mRNA to respiratory cells.
Oliwia Andries, M. de Filette, S. De Smedt, J. Demeester +3 more
2013Journal of Controlled Release61 citations
Semantic Scholar
A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
Bram Bogaert, F. Sauvage, Roberta Guagliardo, C. Muntean +13 more
2022Journal of Controlled Release57 citations Open access
Semantic Scholar
Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates.
S. Van Herck, Kim Deswarte, Lutz Nuhn, Zifu Zhong +8 more
2018Journal of the American Chemical Society52 citations
Semantic Scholar
Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles.
K. Braeckmans, K. Buyens, B. Naeye, Dries Vercauteren +6 more
2010Journal of Controlled Release51 citations
Semantic Scholar
Various ways to improve whole cancer cell vaccines
L. Cicchelero, H. de Rooster, N. Sanders
2014Expert Review of Vaccines50 citations
Semantic Scholar
Potent lymphatic translocation and spatial control over innate immune activation by polymer-lipid amphiphile conjugates of small molecule TLR7/8 agonists.
J. D. de Vrieze, Benoit Louage, Kim Deswarte, Zifu Zhong +10 more
2019Angewandte Chemie49 citations Open access
Semantic Scholar
Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles.
Bart Geers, I. Lentacker, A. Alonso, N. Sanders +3 more
2011Molecular Pharmaceutics49 citations Open access
Semantic Scholar
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators
Anne Huppertsberg, L. Kaps, Zifu Zhong, Sascha Schmitt +20 more
2021Journal of the American Chemical Society47 citations Open access
Semantic Scholar
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity
S. McCafferty, A. K. M. Ashiqul Haque, Aster Vandierendonck, Brian Weidensee +13 more
2022Molecular Therapy46 citations Open access
Semantic Scholar
Topical imiquimod yields systemic effects due to unintended oral uptake
L. Grine, Sophie Steeland, S. Van Ryckeghem, M. Ballegeer +5 more
2016Scientific Reports46 citations Open access
Semantic Scholar
Synthetic biology devices and circuits for RNA-based ‘smart vaccines’: a propositional review
Oliwia Andries, T. Kitada, Katie Bodner, N. Sanders +1 more
2015Expert Review of Vaccines44 citations
Semantic Scholar
The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration
L. Van Hoecke, K. Roose, M. Ballegeer, Zifu Zhong +4 more
2020Molecular Therapy: Nucleic Acids42 citations Open access
Semantic Scholar
Comparison of In Vivo Optical Systems for Bioluminescence and Fluorescence Imaging
Steven K. Cool, Koen Breyne, E. Meyer, S. De Smedt +1 more
2013Journal of Fluorescence40 citations
Semantic Scholar
Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer
Jonas Steenbrugge, Niels Vander Elst, K. Demeyere, O. De Wever +5 more
2019Frontiers in Immunology37 citations Open access
Semantic Scholar
Corticosteroids and cellulose purification improve respectively the in vivo translation and vaccination efficacy of self-amplifying mRNAs.
Zifu Zhong, S. Mccafferty, L. Opsomer, Hai-Xiu Wang +6 more
2021Molecular Therapy34 citations Open access
Semantic Scholar
Combination of interleukin-12 gene therapy, metronomic cyclophosphamide and DNA cancer vaccination directs all arms of the immune system towards tumor eradication.
S. Denies, L. Cicchelero, Isabel Van Audenhove, N. Sanders
2014Journal of Controlled Release33 citations
Semantic Scholar
Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death
M. Vinken, E. Decrock, E. De Vuyst, M. De Bock +7 more
2010Cellular and Molecular Life Sciences33 citations Open access
Semantic Scholar
Comparison of the gene transfer efficiency of mRNA/GL67 and pDNA/GL67 complexes in respiratory cells.
Oliwia Andries, M. de Filette, J. Rejman, S. De Smedt +6 more
2012Molecular Pharmaceutics32 citations
Semantic Scholar
Mucosal Vaccination Against Periodontal Disease: Current Status and Opportunities
V. Vaernewyck, B. Arzi, N. Sanders, E. Cox +1 more
2021Frontiers in Immunology31 citations Open access
Semantic Scholar
In vivo validation of a reversible small molecule-based switch for synthetic self-amplifying mRNA regulation.
Sean Mc Cafferty, Joyca De Temmerman, T. Kitada, Jacob R. Becraft +6 more
2020Molecular Therapy31 citations Open access
Semantic Scholar
Vaccination of Mice Using the West Nile Virus E-Protein in a DNA Prime-Protein Boost Strategy Stimulates Cell-Mediated Immunity and Protects Mice against a Lethal Challenge
M. de Filette, Silke Soehle, S. Ulbert, Justin M. Richner +7 more
2014PLoS ONE31 citations Open access
Semantic Scholar
A Lipid-Polyglutamate Nanoparticle Vaccine Platform
Dorien Van Lysebetten, A. Malfanti, Kim Deswarte, K. Koynov +14 more
2021ACS Applied Materials and Interfaces30 citations Open access
Semantic Scholar
Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs.
Bregje Leyman, H. Huysmans, Séan Mc Cafferty, F. Combes +3 more
2018Molecular Pharmaceutics27 citations
Semantic Scholar
Aerosolized Non-viral Nucleic Acid Delivery in the Vaginal Tract of Pigs
K. Remaut, Evelien De Clercq, Oliwia Andries, K. Rombouts +8 more
2015Pharmaceutical Research25 citations
Semantic Scholar
Non-Classical ProIL-1beta Activation during Mammary Gland Infection Is Pathogen-Dependent but Caspase-1 Independent
Koen Breyne, Steven K. Cool, D. Demon, K. Demeyere +6 more
2014PLoS ONE25 citations Open access
Semantic Scholar
Visible Light-Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)-Lipids for mRNA Lipid Nanoparticle Formulation.
Bianka Golba, Matthieu Soete, Zifu Zhong, N. Sanders +3 more
2023Angewandte Chemie22 citations Open access
Semantic Scholar
Immunogenicity and safety of xenogeneic vascular endothelial growth factor receptor-2 DNA vaccination in mice and dogs
S. Denies, L. Cicchelero, I. Polis, N. Sanders
2016OncoTarget21 citations Open access
Semantic Scholar
Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.
Laure Lambricht, K. Vanvarenberg, A. De Beuckelaer, L. Van Hoecke +7 more
2016Molecular Therapy21 citations Open access
Semantic Scholar

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