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C. Bortner · SciRah

Researcher profile · Semantic Scholar

C. Bortner

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C. Bortner — researcher profile on SciRah

h-index: 40
Works: 95
Citations: 7,746

Most-cited papers

The role of DNA fragmentation in apoptosis.
C. Bortner, N. Oldenburg, J. Cidlowski
1995Trends in Cell Biology642 citations
Semantic Scholar
Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.
C. Trempus, R. Morris, C. Bortner, G. Cotsarelis +3 more
2003Journal of Investigative Dermatology602 citations Open access
Semantic Scholar
A Primary Role for K+ and Na+ Efflux in the Activation of Apoptosis*
C. Bortner, F. Hughes, J. Cidlowski
1997Journal of Biological Chemistry584 citations Open access
Semantic Scholar
Intracellular K+ Suppresses the Activation of Apoptosis in Lymphocytes*
F. Hughes, C. Bortner, G. Purdy, J. Cidlowski
1997Journal of Biological Chemistry489 citations Open access
Semantic Scholar
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I. Vitale, F. Pietrocola, E. Guilbaud, S. Aaronson +224 more
2023Cell Death and Differentiation346 citations Open access
Semantic Scholar
Caspase Independent/Dependent Regulation of K+, Cell Shrinkage, and Mitochondrial Membrane Potential during Lymphocyte Apoptosis*
C. Bortner, J. Cidlowski
1999Journal of Biological Chemistry303 citations Open access
Semantic Scholar
A necessary role for cell shrinkage in apoptosis.
C. Bortner, J. Cidlowski
1998Biochemical Pharmacology268 citations
Semantic Scholar
Cell shrinkage and monovalent cation fluxes: role in apoptosis.
C. Bortner, J. Cidlowski
2007Archives of Biochemistry and Biophysics261 citations Open access
Semantic Scholar
Apoptotic volume decrease and the incredible shrinking cell
C. Bortner, J. Cidlowski
2002Cell Death and Differentiation244 citations
Semantic Scholar
Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes.
C. Bortner, J. Cidlowski
1996American Journal of Physiology229 citations
Semantic Scholar
Cell Sorting Experiments Link Persistent Mitochondrial DNA Damage with Loss of Mitochondrial Membrane Potential and Apoptotic Cell Death*
J. Santos, Ľ. Hunáková, Yi-Ming Chen, C. Bortner +1 more
2003Journal of Biological Chemistry207 citations Open access
Semantic Scholar
Uncoupling Cell Shrinkage from Apoptosis Reveals That Na+ Influx Is Required for Volume Loss during Programmed Cell Death*
C. Bortner, J. Cidlowski
2003Journal of Biological Chemistry195 citations Open access
Semantic Scholar
Modification of Alternative Splicing of Bcl-x Pre-mRNA in Prostate and Breast Cancer Cells
D. Mercatante, C. Bortner, J. Cidlowski, R. Kole
2001Journal of Biological Chemistry176 citations Open access
Semantic Scholar
Plasma Membrane Depolarization without Repolarization Is an Early Molecular Event in Anti-Fas-induced Apoptosis*
C. Bortner, M. Gómez-Angelats, J. Cidlowski
2001Journal of Biological Chemistry168 citations Open access
Semantic Scholar
The role of apoptotic volume decrease and ionic homeostasis in the activation and repression of apoptosis
C. Bortner, J. Cidlowski
2004Pflügers Archiv164 citations
Semantic Scholar
CD34 expression by hair follicle stem cells is required for skin tumor development in mice.
C. Trempus, R. Morris, M. Ehinger, Amy R Elmore +13 more
2007Cancer Research148 citations Open access
Semantic Scholar
The biochemistry and molecular biology of glucocorticoid-induced apoptosis in the immune system.
J. Cidlowski, K. L. King, R. Evans-Storms, J. Montague +2 more
1996Recent Progress in Hormone Research135 citations
Semantic Scholar
Cellular mechanisms for the repression of apoptosis.
C. Bortner, J. Cidlowski
2002Annual Review of Pharmacology and Toxicology128 citations
Semantic Scholar
Protein Kinase C (PKC) Inhibits Fas Receptor-induced Apoptosis through Modulation of the Loss of K+ and Cell Shrinkage
M. Gómez-Angelats, C. Bortner, J. Cidlowski
2000Journal of Biological Chemistry125 citations Open access
Semantic Scholar
Ion channels and apoptosis in cancer
C. Bortner, J. Cidlowski
2014Philosophical Transactions of the Royal Society B: Biological Sciences117 citations Open access
Semantic Scholar
Potential Roles of Electrogenic Ion Transport and Plasma Membrane Depolarization in Apoptosis
R. Franco, C. Bortner, J. Cidlowski
2006Journal of Membrane Biology113 citations Open access
Semantic Scholar
Nuclear Orphan Receptor TAK1/TR4-Deficient Mice Are Protected Against Obesity-Linked Inflammation, Hepatic Steatosis, and Insulin Resistance
H. Kang, K. Okamoto, Yong-Sik Kim, Y. Takeda +7 more
2010Diabetes103 citations Open access
Semantic Scholar
Transcriptional profiling reveals a role for RORalpha in regulating gene expression in obesity-associated inflammation and hepatic steatosis.
H. Kang, K. Okamoto, Y. Takeda, J. Beak +6 more
2011Physiological Genomics90 citations Open access
Semantic Scholar
Stimulation of Kv1.3 Potassium Channels by Death Receptors during Apoptosis in Jurkat T Lymphocytes*
N. M. Storey, M. Gómez-Angelats, C. Bortner, D. Armstrong +1 more
2003Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Differential Involvement of Initiator Caspases in Apoptotic Volume Decrease and Potassium Efflux during Fas- and UV-induced Cell Death*
Collin C. Q. Vu, C. Bortner, J. Cidlowski
2001Journal of Biological Chemistry85 citations Open access
Semantic Scholar
Low level, long‐term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: Potential role in skin co‐carcinogenesis
J. Pi, Yu-Ying He, C. Bortner, Jian-Li Huang +8 more
2005International Journal of Cancer84 citations Open access
Semantic Scholar
CD44 Plays a Critical Role in Regulating Diet-Induced Adipose Inflammation, Hepatic Steatosis, and Insulin Resistance
H. Kang, Grace Liao, Laura M. DeGraff, K. Gerrish +3 more
2013PLoS ONE83 citations Open access
Semantic Scholar
On the mechanism of ionic regulation of apoptosis: would the Na+/K+‐ATPase please stand up?
M. Panayiotidis, C. Bortner, J. Cidlowski
2006Acta Physiologica79 citations
Semantic Scholar
A necessary role for reduced intracellular potassium during the DNA degradation phase of apoptosis.
J. Montague, C. Bortner, F. Hughes, J. Cidlowski
1999Steroids72 citations
Semantic Scholar
Glucocorticoid-Induced Plasma Membrane Depolarization during Thymocyte Apoptosis: Association with Cell Shrinkage and Degradation of the Na+/K+-Adenosine Triphosphatase.
C. L. Mann, C. Bortner, C. Jewell, J. Cidlowski
2001Endocrinology71 citations Open access
Semantic Scholar
Cationic Gradient Reversal and Cytoskeleton-independent Volume Regulatory Pathways Define an Early Stage of Apoptosis*
C. Bortner, Maria I. Sifre, J. Cidlowski
2008Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Arsenic-induced alterations in the contact hypersensitivity response in Balb/c mice.
R. Patterson, L. Vega, K. Trouba, C. Bortner +1 more
2004Toxicology and Applied Pharmacology69 citations
Semantic Scholar
Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells
J. Joo, E. Ueda, C. Bortner, Xiao-Ping Yang +2 more
2015Biochemical Pharmacology67 citations Open access
Semantic Scholar
Ions, the Movement of Water and the Apoptotic Volume Decrease
C. Bortner, J. Cidlowski
2020Frontiers in Cell and Developmental Biology66 citations Open access
Semantic Scholar
Cell volume regulation in immune cell apoptosis
M. Gómez-Angelats, C. Bortner, J. Cidlowski
2000Cell and Tissue Research66 citations
Semantic Scholar
Glutathione Depletion and Disruption of Intracellular Ionic Homeostasis Regulate Lymphoid Cell Apoptosis*
R. Franco, Wayne I. Dehaven, Maria I. Sifre, C. Bortner +1 more
2008Journal of Biological Chemistry63 citations Open access
Semantic Scholar
A Selective Requirement for Elevated Calcium in DNA Degradation, but Not Early Events in Anti-Fas-induced Apoptosis*
A. Scoltock, C. Bortner, G. St. J. Bird, J. Putney +1 more
2000Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway.
W. Qu, C. Bortner, T. Sakurai, M. Hobson +1 more
2002Carcinogenesis61 citations
Semantic Scholar
Complement receptor C5aR1/CD88 and dipeptidyl peptidase-4/CD26 define distinct hematopoietic lineages of dendritic cells
H. Nakano, T. Moran, Keiko Nakano, K. Gerrish +2 more
2015Journal of Immunology54 citations Open access
Semantic Scholar
Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways
Linda Yu, P. Das, Alejandra J. Vall, Yi-Tang Yan +7 more
2019Molecular and Cellular Endocrinology41 citations Open access
Semantic Scholar
Mitochondrial DNA-depleted A549 cells are resistant to bleomycin.
S. Brar, Joel N. Meyer, C. Bortner, B. Van Houten +1 more
2012American Journal of Physiology - Lung cellular and Molecular Physiology38 citations Open access
Semantic Scholar
Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis
H. Kang, Liang-Yu Chen, Kristin Lichti-Kaiser, Grace Liao +5 more
2016Stem Cells36 citations Open access
Semantic Scholar
NITRIC OXIDE REVERSES DRUG RESISTANCE BY INHIBITING ATPASE ACTIVITY OF P-GLYCOPROTEIN IN HUMAN MULTI-DRUG RESISTANT CANCER CELLS
B. K. Sinha, C. Bortner, R. Mason, R. E. Cannon
2018Biochimica et Biophysica Acta - General Subjects35 citations Open access
Semantic Scholar
An Endocrine-disrupting Chemical, Fenvalerate, Induces Cell Cycle Progression and Collagen Type I Expression in Human Uterine Leiomyoma and Myometrial Cells
Xiao-Hua Gao, Linda Yu, Lysandra Castro, A. B. Moore +4 more
2010Toxicology Letters35 citations Open access
Semantic Scholar
Identification of Dss1 as a 12-O-Tetradecanoylphorbol-13-acetate-responsive Gene Expressed in Keratinocyte Progenitor Cells, with Possible Involvement in Early Skin Tumorigenesis*
Sung-Jen Wei, C. Trempus, R. E. Cannon, C. Bortner +1 more
2003Journal of Biological Chemistry33 citations Open access
Semantic Scholar
The Nucleolus Exhibits an Osmotically Regulated Gatekeeping Activity That Controls the Spatial Dynamics and Functions of Nucleolin*
Ling Yang, J. Reece, Jaiesoon Cho, C. Bortner +1 more
2008Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Age-dependent skin tumorigenesis and transgene expression in the Tg.AC (v-Ha-ras) transgenic mouse.
Michael St. J. Battalora, J. Spalding, C. Szczesniak, James E. Cape +5 more
2001Carcinogenesis29 citations Open access
Semantic Scholar
Murine Glucocorticoid Receptors Orchestrate B-cell Migration Selectively between Bone Marrow and Blood
D. Cain, C. Bortner, David Díaz-Jiménez, M. Petrillo +2 more
2020Journal of Immunology27 citations Open access
Semantic Scholar
Osmotic Stress Resistance Imparts Acquired Anti-apoptotic Mechanisms in Lymphocytes*
C. Bortner, A. Scoltock, Maria I. Sifre, J. Cidlowski
2012Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Flow cytometric analysis of cell shrinkage and monovalent ions during apoptosis.
C. Bortner, J. Cidlowski
2001Methods in Cell Biology25 citations
Semantic Scholar

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