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D. Frenkel · SciRah

Researcher profile · Semantic Scholar

D. Frenkel

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D. Frenkel — researcher profile on SciRah

h-index: 39
Works: 109
Citations: 6,723

Most-cited papers

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway
J. Imitola, K. Raddassi, K. Park, Franz-Josef Mueller +8 more
2004Proceedings of the National Academy of Sciences of the United States of America1,133 citations Open access
Semantic Scholar
Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria.
L. Adler-Abramovich, Lilach Vaks, Ohad Carny, D. Trudler +4 more
2012Nature Chemical Biology414 citations Open access
Semantic Scholar
Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+CD25−LAP+ T cells
H. Ochi, Michal Abraham, H. Ishikawa, D. Frenkel +8 more
2006Nature Medicine247 citations
Semantic Scholar
Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease
D. Farfara, Veronica Lifshitz, D. Frenkel
2008Journal of Cellular and Molecular Medicine230 citations Open access
Semantic Scholar
Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis.
Alexandre S. Basso, D. Frenkel, F. Quintana, F. Costa-Pinto +7 more
2008Journal of Clinical Investigation217 citations Open access
Semantic Scholar
Scara1 deficiency impairs clearance of soluble Amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression
D. Frenkel, Kim Wilkinson, Lingzhi Zhao, S. Hickman +6 more
2013Nature Communications209 citations Open access
Semantic Scholar
Orally Administrated Cinnamon Extract Reduces β-Amyloid Oligomerization and Corrects Cognitive Impairment in Alzheimer's Disease Animal Models
Anat Frydman-Marom, A. Levin, D. Farfara, T. Benromano +7 more
2011PLoS ONE203 citations Open access
Semantic Scholar
Immunology and immunotherapy of Alzheimer's disease
H. Weiner, D. Frenkel
2006Nature reviews. Immunology196 citations Open access
Semantic Scholar
Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease.
D. Frenkel, R. Maron, D. Burt, H. Weiner
2005Journal of Clinical Investigation175 citations Open access
Semantic Scholar
Filamentous phage as vector-mediated antibody delivery to the brain
D. Frenkel, B. Solomon
2002Proceedings of the National Academy of Sciences of the United States of America173 citations Open access
Semantic Scholar
Immunology and immunotherapy of Alzheimer's disease
H. Weiner, D. Frenkel
2006Nature reviews. Immunology167 citations
Semantic Scholar
Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model
L. Avrahami, D. Farfara, Maya Shaham-Kol, R. Vassar +2 more
2012Journal of Biological Chemistry164 citations Open access
Semantic Scholar
Nasal Vaccination with Myelin Oligodendrocyte Glycoprotein Reduces Stroke Size by Inducing IL-10-Producing CD4+ T Cells1
D. Frenkel, Zhi-Hong Huang, R. Maron, Djordje N. Koldzic +3 more
2003Journal of Immunology162 citations Open access
Semantic Scholar
Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes
T. Iram, Z. Ramirez-Ortiz, M. Byrne, Uwanda Coleman +4 more
2016Journal of Neuroscience161 citations Open access
Semantic Scholar
Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke.
D. Frenkel, Zhi-Hong Huang, R. Maron, Djordje N. Koldzic +2 more
2005Journal of Neurological Sciences140 citations
Semantic Scholar
Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application
D. Trudler, D. Farfara, D. Frenkel
2010Mediators of Inflammation124 citations Open access
Semantic Scholar
Impaired Autophagy in APOE4 Astrocytes
S. Simonovitch, Eran Schmukler, Alina Bespalko, T. Iram +5 more
2016Journal of Alzheimer's Disease119 citations
Semantic Scholar
Inflammatory events at blood–brain barrier in neuroinflammatory and neurodegenerative disorders: Implications for clinical disease
H. D. de Vries, G. Kooij, D. Frenkel, S. Georgopoulos +2 more
2012Epilepsia114 citations Open access
Semantic Scholar
Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection.
T. Iram, D. Trudler, David Kain, S. Kanner +6 more
2016Neurobiology of Disease113 citations Open access
Semantic Scholar
Inhibition of Autoimmune Diabetes by Oral Administration of Anti-CD3 Monoclonal Antibody
H. Ishikawa, H. Ochi, Mei-Ling Chen, D. Frenkel +2 more
2007Diabetes111 citations Open access
Semantic Scholar
Low-Level Laser Therapy Ameliorates Disease Progression in a Mouse Model of Alzheimer’s Disease
D. Farfara, Hana Tuby, D. Trudler, Ella Doron-Mandel +4 more
2015Journal of Molecular Neuroscience105 citations
Semantic Scholar
DJ‐1 deficiency impairs autophagy and reduces alpha‐synuclein phagocytosis by microglia
Y. Nash, Eran Schmukler, D. Trudler, R. Pinkas-Kramarski +1 more
2017Journal of Neurochemistry100 citations
Semantic Scholar
DJ‐1 deficiency triggers microglia sensitivity to dopamine toward a pro‐inflammatory phenotype that is attenuated by rasagiline
D. Trudler, O. Weinreb, S. Mandel, M. B. H. Youdim +1 more
2014Journal of Neurochemistry96 citations
Semantic Scholar
Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells.
Xing-Min Zhang, J. Reddy, H. Ochi, D. Frenkel +2 more
2006International Immunology95 citations
Semantic Scholar
Behavioral and neural effects of intra-striatal infusion of anti-streptococcal antibodies in rats
Dafna Lotan, I. Benhar, K. Alvarez, Adita Mascaro-Blanco +4 more
2014Brain, behavior, and immunity94 citations Open access
Semantic Scholar
Reduction of beta-amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization.
D. Frenkel, I. Dewachter, F. Van Leuven, B. Solomon
2003Vaccine92 citations
Semantic Scholar
Autophagy in Parkinson’s Disease
Lior Nechushtai, D. Frenkel, R. Pinkas-Kramarski
2023Biomolecules84 citations Open access
Semantic Scholar
Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation.
Ronit Shapira, B. Solomon, S. Efrati, D. Frenkel +1 more
2018Neurobiology of Aging75 citations
Semantic Scholar
Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model
Wenqiang Chen, Qian Huang, Ekaterina Lazdon, A. Gomes +6 more
2023Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
Semantic Scholar
γ‐Secretase component presenilin is important for microglia β‐amyloid clearance
D. Farfara, D. Trudler, N. Segev-Amzaleg, R. Galron +2 more
2011Annals of Neurology56 citations
Semantic Scholar
A nasal proteosome adjuvant activates microglia and prevents amyloid deposition
D. Frenkel, L. Puckett, S. Petrović, W. Xia +7 more
2008Annals of Neurology55 citations Open access
Semantic Scholar
Microglia and Parkinson's disease: footprints to pathology
Ekaterina Lazdon, Nofar Stolero, D. Frenkel
2020Journal of neural transmission51 citations
Semantic Scholar
Generation of auto-antibodies towards Alzheimer's disease vaccination.
D. Frenkel, N. Kariv, B. Solomon
2001Vaccine50 citations
Semantic Scholar
Homocysteine fibrillar assemblies display cross-talk with Alzheimer’s disease β-amyloid polypeptide
Dorin Sade Yazdi, Dana Laor Bar-Yosef, Hanaa Adsi, Topaz Kreiser +10 more
2021Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Characterization of brain lesions in a mouse model of progressive multiple sclerosis.
H. Levy, Y. Assaf, D. Frenkel
2010Experimental Neurology47 citations
Semantic Scholar
Insulin-coated gold nanoparticles as a new concept for personalized and adjustable glucose regulation.
Malka Shilo, Peter Berenstein, Tamar Dreifuss, Y. Nash +6 more
2015Nanoscale41 citations
Semantic Scholar
New immunosuppressive approaches: Oral administration of CD3-specific antibody to treat autoimmunity
H. Ochi, Michal Abraham, H. Ishikawa, D. Frenkel +8 more
2008Journal of Neurological Sciences39 citations Open access
Semantic Scholar
Preconditioning to mild oxidative stress mediates astroglial neuroprotection in an IL-10-dependent manner.
N. Segev-Amzaleg, D. Trudler, D. Frenkel
2013Brain, behavior, and immunity38 citations
Semantic Scholar
Immunotherapy of cereberovascular amloidosis in a transgenic mouse model
Veronica Lifshitz, R. Weiss, T. Benromano, Einat Kfir +7 more
2011Neurobiology of Aging37 citations Open access
Semantic Scholar
Alginate‐coated magnetic nanoparticles for noninvasive MRI of extracellular calcium
A. Bar-Shir, L. Avram, Shani Yariv-Shoushan, D. Anaby +6 more
2014NMR in Biomedicine36 citations
Semantic Scholar
Effects of Immunomodulatory Substances on Phagocytosis of Aβ 1–42 by Human Microglia
E. Hjorth, D. Frenkel, H. Weiner, M. Schultzberg
2010International Journal of Alzheimer's Disease34 citations Open access
Semantic Scholar
Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.
D. Frenkel, A. Pachori, Lu-Nan Zhang, Adi Dembinsky-Vaknin +4 more
2009International Immunology34 citations Open access
Semantic Scholar
The dialog between neurons and microglia in Alzheimer's disease: The neurotransmitters view
Nofar Stolero, D. Frenkel
2020Journal of Neurochemistry30 citations
Semantic Scholar
Anti‐inflammatory and protective effects of MT‐031, a novel multitarget MAO‐A and AChE/BuChE inhibitor in scopolamine mouse model and inflammatory cells
Wei Liu, A. Rabinovich, Y. Nash, D. Frenkel +3 more
2017Neuropharmacology28 citations
Semantic Scholar
TGF-β1 affects endothelial cell interaction with macrophages and T cells leading to the development of cerebrovascular amyloidosis.
R. Weiss, Veronica Lifshitz, D. Frenkel
2011Brain, behavior, and immunity28 citations
Semantic Scholar
New insights on Parkinson’s disease genes: the link between mitochondria impairment and neuroinflammation
D. Trudler, Y. Nash, D. Frenkel
2015Journal of neural transmission25 citations
Semantic Scholar
Expression of Scavenger receptor A on antigen presenting cells is important for CD4+ T-cells proliferation in EAE mouse model
Hilit Levy-barazany, D. Frenkel
2012Journal of Neuroinflammation25 citations Open access
Semantic Scholar
A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia.
D. Raz-Prag, R. Galron, N. Segev-Amzaleg, A. Solomon +3 more
2011American Journal of Pathology25 citations Open access
Semantic Scholar
Brain MRI of nasal MOG therapeutic effect in relapsing-progressive EAE.
H. L. Barazany, D. Barazany, L. Puckett, S. Blanga-Kanfi +5 more
2014Experimental Neurology21 citations
Semantic Scholar
Insulin-degrading enzyme higher in subjects with metabolic syndrome
Y. Sofer, Y. Nash, E. Osher, O. Fursht +18 more
2021Endocrine18 citations
Semantic Scholar

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