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Natalia Gruba · SciRah

Researcher profile · Semantic Scholar

Natalia Gruba

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Natalia Gruba — researcher profile on SciRah

h-index: 12
Works: 44
Citations: 365

Most-cited papers

Substrate profiling of Zika virus NS2B‐NS3 protease
Natalia Gruba, Jose Ignacio Rodriguez Martinez, Renata Grzywa, M. Wysocka +6 more
2016FEBS Letters49 citations Open access
Semantic Scholar
Biochemical and Structural Characterization of SplD Protease from Staphylococcus aureus
Michal Zdzalik, M. Kalińska, M. Wysocka, J. Stec-Niemczyk +14 more
2013PLoS ONE31 citations Open access
Semantic Scholar
Three wavelength substrate system of neutrophil serine proteinases.
M. Wysocka, A. Lesner, Natalia Gruba, B. Korkmaz +4 more
2012Analytical Chemistry25 citations
Semantic Scholar
Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia.
Irena Audzeyenka, P. Rachubik, D. Rogacka, M. Typiak +8 more
2020Biochimica et biophysica acta. Molecular cell research23 citations Open access
Semantic Scholar
Substrate specificity of human matriptase-2.
M. Wysocka, Natalia Gruba, A. Miecznikowska, Jadwiga Popow-Stellmaszyk +6 more
2014Biochimie23 citations
Semantic Scholar
Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity
Natalia Gruba, Ewa Bielecka, M. Wysocka, Anna Wojtysiak +17 more
2019International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Structural Determinants of Substrate Specificity of SplF Protease from Staphylococcus aureus
N. Stach, A. Karim, P. Golik, Radosław Kitel +9 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Bladder cancer detection using a peptide substrate of the 20S proteasome
Natalia Gruba, M. Wysocka, Magdalena Brzezińska, D. Dębowski +6 more
2016The FEBS Journal17 citations
Semantic Scholar
SP-1, a Serine Protease from the Gut Microbiota, Influences Colitis and Drives Intestinal Dysbiosis in Mice
Aïcha Kriaa, Amin Jablaoui, Soufien Rhimi, Souha Soussou +7 more
2021Cells16 citations Open access
Semantic Scholar
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.
C. Guarino, Natalia Gruba, Renata Grzywa, Edyta Dyguda-Kazimierowicz +11 more
2018Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
One Step Beyond: Design of Substrates Spanning Primed Positions of Zika Virus NS2B-NS3 Protease.
Natalia Gruba, Jose Ignacio Rodriguez Martinez, Renata Grzywa, M. Wysocka +7 more
2018ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
PEGylated substrates of NSP4 protease: A tool to study protease specificity
M. Wysocka, Natalia Gruba, Renata Grzywa, A. Giełdoń +7 more
2016Scientific Reports14 citations Open access
Semantic Scholar
ADAM10 as a major activator of reactive oxygen species production and klotho shedding in podocytes under diabetic conditions.
A. Piwkowska, P. Rachubik, M. Typiak, Tomasz Kulesza +6 more
2024Biochemical Pharmacology12 citations
Semantic Scholar
Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)—A CleavEx Based Analysis
K. Falkowski, Ewa Bielecka, I. Thøgersen, O. Bocheńska +22 more
2020bioRxiv11 citations Open access
Semantic Scholar
A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome
M. Wysocka, A. Romanowska, Natalia Gruba, Michalina Michalska +2 more
2020International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Elastolytic activity is associated with inflammation in bladder cancer.
Natalia Gruba, L. Stachurski, A. Lesner
2021Journal of Biochemistry (Tokyo)8 citations
Semantic Scholar
Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome.
Natalia Gruba, M. Wysocka, Magdalena Brzezińska, D. Dębowski +3 more
2016Analytical Biochemistry8 citations Open access
Semantic Scholar
Involvement of ADAM17-Klotho Crosstalk in High Glucose-Induced Alterations of Podocyte Function
D. Rogacka, P. Rachubik, M. Typiak, Tomasz Kulesza +7 more
2025International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Initial study of the detection of ADAM 10 in the urine of type-2 diabetic patients.
Natalia Gruba, A. Piwkowska, A. Lesner
2023Bioorganic chemistry (Print)7 citations
Semantic Scholar
Detection of ADAM15 in urine from patients with bladder cancer.
Natalia Gruba, M. Musielak, Wiktoria Rejmak, A. Lesner
2022Analytical Biochemistry6 citations
Semantic Scholar
Non‐Proteasomal Urine Activity in Bladder Cancer
Natalia Gruba, L. Stachurski, A. Lesner
2021Chemistry and Biodiversity6 citations
Semantic Scholar
Design and synthesis of new substrates of HtrA2 protease.
M. Wysocka, Anna Wojtysiak, M. Okońska, Natalia Gruba +7 more
2015Analytical Biochemistry6 citations
Semantic Scholar
Optimization of fluorescent substrates for ADAM17 and their utility in the detection of diabetes.
Honorata Sikora, Natalia Gruba, M. Wysocka, A. Piwkowska +1 more
2023Analytical Biochemistry5 citations
Semantic Scholar
Simplified Theta-defensin [Ser3,7,12,16] RTD-2 Analog Is Involved in Proteasomal Degradation Pathway in Breast Cancer
Joanna Pianka, Natalia Gruba, K. Kitowska, Kamil Mieczkowski +3 more
2021Anticancer Research5 citations
Semantic Scholar
Utility of FRET substrates in bladder cancer diagnosis.
Natalia Gruba, L. Stachurski, A. Lesner
2026Bioorganic chemistry (Print)3 citations
Semantic Scholar
Caspase-like activity is associated with bacterial infection of the urine in urinary tract diseases.
Natalia Gruba, Honorata Sikora, Justyna Ciesielska, Wiktoria Rejmak +1 more
2024Analytical Biochemistry3 citations
Semantic Scholar
Novel tools to study West Nile virus NS3 protease activity.
Joanna Pianka, Natalia Gruba, A. Lesner
2023Bioorganic chemistry (Print)2 citations
Semantic Scholar
Selection of Effective HTRA3 Activators Using Combinatorial Chemistry.
M. Wysocka, Kamila Sychowska, Natalia Gruba, Lukasz Winiarski +11 more
2017ACS Combinatorial Science2 citations
Semantic Scholar
Proteasuria: extending an existing term into a framework for concentration-based and catalytic protease diagnostics in urine, with emphasis on activity-based methods.
Adam Lesner, Natalia Gruba, M. Wysocka
2026Critical reviews in clinical laboratory sciences0 citations
Semantic Scholar
Optimization of fluorogenic CatS substrates for monitoring cancer-associated proteolytic activity.
E. Nowakowska, Jakub Iwanicki, Adam Lesner, Natalia Gruba
2026Analytical Biochemistry0 citations
Semantic Scholar
BADANIA PRZESIEWOWE W RAKU JELITA GRUBEGO
Natalia Gruba
2026Wiadomości Chemiczne0 citations
Semantic Scholar
Chromogenic and FRET peptide substrates, quantum-dot peptide conjugates and electrochemical peptide interfaces: A 25-year journey from combinatorial chemistry to clinical readouts-A viewpoint.
Adam Lesner, Natalia Gruba, M. Wysocka
2026The FEBS Journal0 citations Open access
Semantic Scholar
“We are thrown a hint”: A. Adamov’s play “In Fiacre” and J. Lacan’s III Seminar
Natalia Gruba
2024The South Pole. Studies on the history of modern Western philosophy0 citations
Semantic Scholar
Nearness and remoteness in the philosophical language of W. Benjamin and M. Heidegger
Natalia Gruba
2024Journal of Integrative Cultural Studies0 citations Open access
Semantic Scholar
KROPKI KWANTOWE JAKO NARZĘDZIA DIAGNOSTYCZNE
Natalia Gruba, Wiktoria Rejmak, Anita Romanowska, Adam Lesner
2024Wiadomości Chemiczne0 citations
Semantic Scholar
PEPTYDY Z WĘZŁEM CYSTEINOWYM JAKO INHIBITORY KALLIKREINY 13
D. Jankowska, Wiktoria Rejmak, Adam Lesner, Natalia Gruba
2024Wiadomości Chemiczne0 citations
Semantic Scholar
WYKORZYSTANIE ENZYMÓW W DIAGNOSTYCE MEDYCZNEJ
Natalia Gruba
2023Wiadomości Chemiczne0 citations
Semantic Scholar
NIEINWAZYJNE BIOMARKERY DO WYKRYWANIA RAKA PĘCHERZA MOCZOWEGO
Natalia Gruba
2022Wiadomości Chemiczne0 citations
Semantic Scholar
MONITOROWANIE AKTYWNOŚCI PROTEOLITYCZNEJ JAKO ELEMENT DIAGNOSTYKI CHORÓB CYWILIZACYJNYCH
Natalia Gruba, Anita Romanowska, Wiktoria Rejmak, Honorata Sikora +2 more
2022Wiadomości Chemiczne0 citations
Semantic Scholar
Novel Class of KLK13 Inhibitors Cysteine Knot
Natalia Gruba, D. Jankowska, Wiktoria Rejmak, A. Lesner
2022Social Science Research Network0 citations Open access
Semantic Scholar
Chemical tools to monitor bladder cancer progression
Natalia Gruba, L. Stachurski, A. Lesner
2022Biomarkers0 citations
Semantic Scholar
Analysis of urinary kallikrein-related peptidase 13 for monitoring bladder cancer
Natalia Gruba, P. Rachubik, A. Piwkowska, A. Lesner
2021Biomarkers0 citations
Semantic Scholar
Session 11 : Synthetic and system biology Lectures L 11 . 1 Synonymous mutations in the light of translational regulation
Natalia Gruba, M. Wysocka, Anna Wojtysiak, Ewa Bielecka +10 more
20160 citations
Semantic Scholar
51074 1 supp 1856750 10htc5
M. Wysocka, Natalia Gruba, Renata Grzywa, A. Giełdoń +7 more
20160 citations
Semantic Scholar

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