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J. Humphrey · SciRah

Researcher profile · Semantic Scholar

J. Humphrey

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J. Humphrey — researcher profile on SciRah

h-index: 16
Works: 36
Citations: 2,174

Most-cited papers

Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial.
Youn H. Kim, M. Bagot, L. Pinter-Brown, A. Rook +81 more
2018The Lancet Oncology567 citations Open access
Semantic Scholar
Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia.
T. Carpenter, E. Imel, M. Ruppe, T. Weber +8 more
2014Journal of Clinical Investigation282 citations Open access
Semantic Scholar
Phase I clinical trial design in cancer drug development.
E. Eisenhauer, P. O'Dwyer, M. Christian, J. Humphrey
2000Journal of Clinical Oncology229 citations
Semantic Scholar
Randomized phase III study of matrix metalloproteinase inhibitor BMS-275291 in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18.
N. Leighl, L. Paz-Ares, J. Douillard, C. Peschel +15 more
2005Journal of Clinical Oncology175 citations
Semantic Scholar
The Design of Phase II Clinical Trials Testing Cancer Therapeutics: Consensus Recommendations from the Clinical Trial Design Task Force of the National Cancer Institute Investigational Drug Steering Committee
L. Seymour, S. P. Ivy, D. Sargent, D. Spriggs +10 more
2010Clinical Cancer Research156 citations Open access
Semantic Scholar
Prolonged Correction of Serum Phosphorus in Adults With X-Linked Hypophosphatemia Using Monthly Doses of KRN23.
E. Imel, Xiao-Ping Zhang, M. Ruppe, T. Weber +9 more
2015Journal of Clinical Endocrinology and Metabolism152 citations Open access
Semantic Scholar
Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor.
A. C. Lockhart, R. Braun, Dao-Hai Yu, Joel R. Ross +10 more
2003Clinical Cancer Research118 citations
Semantic Scholar
Cancer Drug Discovery and Development
J. Humphrey, K. Price, E. Gupta, A. Baxter +3 more
200298 citations Open access
Semantic Scholar
Mogamulizumab versus investigator’s choice of chemotherapy regimen in relapsed/refractory adult T-cell leukemia/lymphoma
A. Phillips, P. Fields, O. Hermine, J. Ramos +15 more
2018Haematologica71 citations Open access
Semantic Scholar
A Phase I Study of Oral BMS-275291, a Novel Nonhydroxamate Sheddase-Sparing Matrix Metalloproteinase Inhibitor, in Patients with Advanced or Metastatic Cancer
N. Rizvi, J. Humphrey, E. Ness, M. Johnson +7 more
2004Clinical Cancer Research59 citations Open access
Semantic Scholar
Effect of four monthly doses of a human monoclonal anti-FGF23 antibody (KRN23) on quality of life in X-linked hypophosphatemia
M. Ruppe, Xiao-Ping Zhang, E. Imel, T. Weber +9 more
2016Bone Reports58 citations Open access
Semantic Scholar
Pharmacokinetics and pharmacodynamics of a human monoclonal anti‐FGF23 antibody (KRN23) in the first multiple ascending‐dose trial treating adults with X‐linked hypophosphatemia
Xiao-Ping Zhang, E. Imel, M. Ruppe, T. Weber +9 more
2015Journal of clinical pharmacology49 citations Open access
Semantic Scholar
Acute renal toxicity associated with suramin in the treatment of prostate cancer
W. Figg, Michael R. Cooper, A. Thibault, D. Headlee +4 more
1994Cancer32 citations Open access
Semantic Scholar
Randomized phase II feasibility study of combining the matrix metalloproteinase inhibitor BMS-275291 with paclitaxel plus carboplatin in advanced non-small cell lung cancer.
J. Douillard, C. Peschel, F. Shepherd, L. Paz-Ares +11 more
2004Lung Cancer25 citations
Semantic Scholar
MANIFEST-2, a Global, Phase 3, Randomized, Double-Blind, Active-Control Study of CPI-0610 and Ruxolitinib Vs. Placebo and Ruxolitinib in JAK-Inhibitor-Naive Myelofibrosis Patients
J. Mascarenhas, C. Harrison, K. Luptakova, Jessica Christo +9 more
2020Blood22 citations Open access
Semantic Scholar
Anti-CCR4 Monoclonal Antibody, Mogamulizumab, Demonstrates Significant Improvement in PFS Compared to Vorinostat in Patients with Previously Treated Cutaneous T-Cell Lymphoma (CTCL): Results from the Phase III MAVORIC Study
Youn H. Kim, M. Bagot, L. Pinter-Brown, A. Rook +29 more
201717 citations
Semantic Scholar
The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial: Long-term outcomes in first-line patients (pts)
C. Ryan, R. Bukowski, R. Figlin, J. Knox +6 more
200712 citations
Semantic Scholar
Parasite antigen-induced IFN-gamma and IL-4 production by cells from pathopermissive and pathoresistant strains of mice infected with Trypanosoma cruzi.
J. Humphrey, Thomas S. McCormick, E. Rowland
1997Journal of Parasitology11 citations Open access
Semantic Scholar
Efficacy of a competitive enzyme-linked immunosorbent assay (cELISA) for estimating prevalence of immunity to rabbit haemorrhagic disease virus (RHDV) in populations of Australian wild rabbits (Oryctolagus cuniculus)
S. McPhee, D. Berman, A. Gonzales, K. Butler +6 more
200210 citations
Semantic Scholar
GCP Data Quality for Early Clinical Development
E. Rock, V. J. Molloy, J. Humphrey
2010Clinical Cancer Research9 citations Open access
Semantic Scholar
Mgta-117, an Anti-CD117 Antibody-Drug Conjugated with Amanitin, in Participants with Relapsed/Refractory Adult Acute Myeloid Leukemia (AML) and Myelodysplasia with Excess Blasts (MDS-EB): Safety, Pharmacokinetics and Pharmacodynamics Initial Findings from a Phase 1/2 Study
P. Westervelt, P. Kebriaei, M. Juckett, A. Artz +15 more
2022Blood6 citations Open access
Semantic Scholar
MPN-343: The BET Inhibitor Pelabresib Decreases Inflammatory Cytokines, Improves Bone Marrow Fibrosis and Function, and Demonstrates Clinical Response Irrespective of Mutation Status in Myelofibrosis Patients in the Phase 2 MANIFEST Trial
O. Zavidij, Patricia J. Keller, Ji-Ke Cui, J. Mertz +19 more
20215 citations
Semantic Scholar
Randomised phase II study of BMS-275291 versus placebo in patients (pts) with stage IIIb or IV non small cell lung cancer (NSCLC) receiving paclitaxel + carboplatin (PC): National Cancer Institute of Canada clinical trials group (NCIC CTG) br.18
J. Douillard, V. Petersen, F. Shepherd, L. Paz-Ares +7 more
20015 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) after ascending single-dose administration in patients with X-linked hypophosphatemia
Xiao-Ping Zhang, T. Carpenter, E. Imel, M. Ruppe +7 more
20144 citations
Semantic Scholar
The BET Inhibitor, CPI-0610, Promotes Myeloid Differentiation in Myelofibrosis Patient Bone Marrow and Peripheral CD34+ Hematopoietic Stem Cells
J. Mertz, Patricia J. Keller, Rosana Meyer, O. Zavidij +17 more
20202 citations Open access
Semantic Scholar
Assessment of Quality of Life Data After 4 Monthly S.C. Doses of a Human Monoclonal Anti-Fibroblast Growth Factor 23 Antibody (KRN23) in Adults with X-linked Hypophosphatemia
M. Ruppe, Xiao-Ping Zhang, E. Imel, T. Weber +9 more
20141 citations
Semantic Scholar
A Phase 2, Open-Label Study to Evaluate the Efficacy and Safety of Mgta-145 in Combination with Plerixafor for the Mobilization of Hematopoietic Stem Cells in Patients with Sickle Cell Anemia
Akshay Sharma, J. Manis, D. Justus, David A. Williams +13 more
2022Blood0 citations Open access
Semantic Scholar
Differences between Japan and rest of world (ROW) in disease presentation and outcome of previously treated adult t-cell leukemia-lymphoma (ATL) using therapy with a monoclonal antibody to CCR4, mogamulizumab (moga).
A. Phillips, S. Horwitz, G. Taylor, J. Humphrey +3 more
20160 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia: The Journal of Clinical Pharmacology
Xiao-Ping Zhang, E. Imel, M. Ruppe, T. Weber +9 more
20150 citations
Semantic Scholar
A randomized, double-blind, placebo-controlled, ascending, single-dose study of a human monoclonal anti-FGF23 antibody (KRN23) in X-linked hypophosphatemia
T. Carpenter, E. Imel, M. Ruppe, T. Weber +8 more
20140 citations
Semantic Scholar
Pharmacokinetics and Pharmacodynamics of a Human Monoclonal Anti-Fibroblast Growth Factor 23 Antibody (KRN23) Following 4 Month Intra-Dose Escalation in Adults with X-Linked Hypophosphatemia
Xiao-Ping Zhang, E. Imel, M. Ruppe, T. Weber +9 more
20140 citations
Semantic Scholar
Efficacy and Safety Following 4 Monthly s.c. Doses of a Human Anti-Fibroblast Growth Factor 23 Antibody (KRN23) in Adults with X-linked Hypophosphatemia
M. Peacock, E. Imel, Xiao-ping Zhang, M. Ruppe +9 more
20140 citations
Semantic Scholar
Measuring the cost-effectiveness (CE) of therapies treating metastatic colorectal cancer (mCRC).
D. Lakdawalla, J. Penrod, R. Maclean, J. Humphrey +1 more
2011Journal of Clinical Oncology0 citations
Semantic Scholar
Investigational Drug Steering Committee Trial Design Task Force of the National Cancer Institute Therapeutics : Consensus Recommendations from the Clinical The Design of Phase II Clinical Trials Testing Cancer
L. Seymour, S. P. Ivy, D. Sargent, D. Spriggs +10 more
20100 citations
Semantic Scholar
Value of Survival Gains In Chronic Myelogenous Leukemia
Wesley Yin, J. Penrod, R. Maclean, J. Humphrey +2 more
20100 citations
Semantic Scholar
Phase I Cl inica l Tria l Des ign in Cancer Drug Development
E. Eisenhauer, P. O'Dwyer, M. Christian, J. Humphrey
20000 citations
Semantic Scholar

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