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R. Screaton · SciRah

Researcher profile · Semantic Scholar

R. Screaton

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R. Screaton — researcher profile on SciRah

h-index: 35
Works: 71
Citations: 7,698

Most-cited papers

Anoikis mechanisms.
S. Frisch, R. Screaton
2001Current Opinion in Cell Biology1,047 citations
Semantic Scholar
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
Seung-Hoi Koo, Lawrence M. Flechner, Ling Qi, Xinmin Zhang +8 more
2005Nature1,041 citations
Semantic Scholar
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.
R. Screaton, M. Conkright, Y. Katoh, J. Best +8 more
2004Cell683 citations Open access
Semantic Scholar
TORCs: transducers of regulated CREB activity.
M. Conkright, G. Canettieri, R. Screaton, Ernesto Guzmán +3 more
2003Molecules and Cells632 citations Open access
Semantic Scholar
cAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2
U. Jhala, G. Canettieri, R. Screaton, R. Kulkarni +6 more
2003531 citations Open access
Semantic Scholar
TRB3 Links the E3 Ubiquitin Ligase COP1 to Lipid Metabolism
Ling Qi, J. Heredia, Judith Y. Altarejos, R. Screaton +11 more
2006Science332 citations
Semantic Scholar
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
U. Jhala, G. Canettieri, R. Screaton, R. Kulkarni +6 more
2003Genes & Development309 citations
Semantic Scholar
Human carcinoembryonic antigen functions as a general inhibitor of anoikis.
Cosme Ordonez, R. Screaton, C. Ilantzis, C. P. Stanners
2000Cancer Research237 citations
Semantic Scholar
Glucose Metabolism and Pancreatic Defects in Spinal Muscular Atrophy
M. Bowerman, K. Swoboda, John-Paul Michalski, Gen-Sheng Wang +7 more
2012Annals of Neurology189 citations Open access
Semantic Scholar
Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation.
C. Ilantzis, L. Demarte, R. Screaton, C. Stanners
2002Neoplasia183 citations Open access
Semantic Scholar
Mutant GNAS drives pancreatic tumorigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
K. Patra, Y. Kato, Yusuke Mizukami, Sebastian A. Widholz +14 more
2018Nature Cell Biology174 citations Open access
Semantic Scholar
Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: A potential link between genome surveillance and apoptosis
R. Screaton, S. Kiessling, O. Sansom, Catherine B. Millar +4 more
2003Proceedings of the National Academy of Sciences of the United States of America143 citations Open access
Semantic Scholar
The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.
U. Lemke, Anja Krones-Herzig, M. B. Diaz, Prachiti Narvekar +9 more
2008Cell Metabolism142 citations Open access
Semantic Scholar
Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2
D. Jansson, A. C. Ng, Accalia Fu, Chantal Depatie +2 more
2008Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
InsP3 Receptor Regulates Hepatic Gluconeogenesis in Fasting and Diabetes
Yiguo Wang, Gang Li, Jason Goode, J. C. Paz +6 more
2012Nature131 citations Open access
Semantic Scholar
Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice.
Accalia Fu, A. C. Ng, Chantal Depatie, N. Wijesekara +7 more
2009Cell Metabolism129 citations Open access
Semantic Scholar
The AMPK-related kinases SIK1 and SIK3 mediate key tumor suppressive effects of LKB1 in NSCLC.
Pablo E. Hollstein, L. Eichner, Sonja N. Brun, A. Kamireddy +11 more
2019Cancer Discovery128 citations Open access
Semantic Scholar
ROMO1 Is an Essential Redox-Dependent Regulator of Mitochondrial Dynamics
Matthew D. Norton, A. C. Ng, S. Baird, A. Dumoulin +5 more
2014Science Signaling121 citations
Semantic Scholar
The Keap1–Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1
R. Sabouny, Erik Fraunberger, M. Geoffrion, A. C. Ng +5 more
2017Antioxidants and Redox Signaling111 citations
Semantic Scholar
Role of AMPK in pancreatic beta cell function.
Accalia Fu, C. Eberhard, R. Screaton
2013Molecular and Cellular Endocrinology106 citations
Semantic Scholar
Carcinoembryonic Antigen, a Human Tumor Marker, Cooperates with Myc and Bcl-2 in Cellular Transformation
R. Screaton, L. Penn, C. Stanners
1997Journal of Cell Biology91 citations Open access
Semantic Scholar
Homozygous mutations in MFN2 cause multiple symmetric lipomatosis associated with neuropathy.
S. Sawyer, Andy Cheuk-Him Ng, A. Innes, J. Wagner +6 more
2015Human Molecular Genetics81 citations Open access
Semantic Scholar
Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone
D. Oropeza, N. Jouvet, L. Budry, J. Campbell +16 more
2015Diabetes77 citations Open access
Semantic Scholar
Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy
Valérie Lefebvre, Qiujiang Du, S. Baird, A. C. Ng +4 more
2013Autophagy74 citations Open access
Semantic Scholar
Role of the SIK2-p35-PJA2 complex in pancreatic beta cell functional compensation
Jun-ichi Sakamaki, Accalia Fu, Courtney Reeks, S. Baird +6 more
2014Nature Cell Biology70 citations Open access
Semantic Scholar
Axl Phosphorylates Elmo Scaffold Proteins To Promote Rac Activation and Cell Invasion
A. Abu-Thuraia, Rosemarie Gauthier, Rony Chidiac, Y. Fukui +3 more
2014Molecular and Cellular Biology68 citations Open access
Semantic Scholar
Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion*
R. Mailloux, Accalia Fu, Christine A. Robson-Doucette, E. Allister +3 more
2012Journal of Biological Chemistry65 citations Open access
Semantic Scholar
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1
G. Canettieri, S. Coni, Michele Della Guardia, V. Nocerino +6 more
2009Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
Semantic Scholar
The Specificity for the Differentiation Blocking Activity of Carcinoembryonic Antigen Resides in Its Glycophosphatidyl-Inositol Anchor
R. Screaton, L. Demarte, P. Dráber, C. Stanners
2000Journal of Cell Biology60 citations Open access
Semantic Scholar
AMPK and Friends: Central Regulators of β Cell Biology.
J. L. Rourke, Queenie Hu, R. Screaton
2018Trends in endocrinology and metabolism45 citations
Semantic Scholar
A role for the CREB co‐activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation
R. Lerner, Chantal Depatie, Guy A. Rutter, R. Screaton +1 more
2009EMBO Reports39 citations Open access
Semantic Scholar
High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation*
Karine Robitaille, J. L. Rourke, J. Mcbane, Accalia Fu +5 more
2016Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Essential Role of TID1 in Maintaining Mitochondrial Membrane Potential Homogeneity and Mitochondrial DNA Integrity
A. C. Ng, S. Baird, R. Screaton
2014Molecular and Cellular Biology37 citations Open access
Semantic Scholar
CRTC2 is required for β-cell function and proliferation.
C. Eberhard, Accalia Fu, Courtney Reeks, R. Screaton
2013Endocrinology36 citations
Semantic Scholar
SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds
Herman H. Cheung, M. St-Jean, S. T. Beug, R. Lejmi-Mrad +5 more
2011Cell Death and Disease35 citations Open access
Semantic Scholar
Beyond Genetics: The Role of Metabolism in Photoreceptor Survival, Development and Repair
Joseph Hanna, L. David, Yacine Touahri, Taylor Fleming +2 more
2022Frontiers in Cell and Developmental Biology32 citations Open access
Semantic Scholar
Radical differences in functions of closely related members of the human carcinoembryonic antigen gene family.
M. Rojas, Luisa DeMarte, R. Screaton, C. Stanners
1996Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research32 citations
Semantic Scholar
Role of the Sik2-p35-Pja2 Complex in Pancreatic Beta Cell Functional Compensation
Jun-ichi Sakamaki, Accalia Fu, Courtney Reeks, Chantal Depatie +5 more
201328 citations Open access
Semantic Scholar
LKB1 couples glucose metabolism to insulin secretion in mice
Accalia Fu, Karine Robitaille, B. Faubert, Courtney Reeks +10 more
2015Diabetologia27 citations Open access
Semantic Scholar
TRB 3 Links the E 3 Ubiquitin Ligase COP 1 to Lipid Metabolism
Ling Qi, J. Heredia, Judith Y. Altarejos, R. Screaton +11 more
200927 citations
Semantic Scholar
Using kinomics to delineate signaling pathways: Control of crtc2/torc2 by the ampk family
Accalia Fu, R. Screaton
2008Cell Cycle25 citations Open access
Semantic Scholar
LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction.
Marc Germain, Angela P. Nguyen, M. Khacho, D. Patten +3 more
2013Human Molecular Genetics24 citations
Semantic Scholar
Transcriptional Activation by MEIS1A in Response to Protein Kinase A Signaling Requires the Transducers of Regulated CREB Family of CREB Co-activators
Siew-Lee Goh, Y. Looi, Huiqing Shen, Jun Fang +5 more
2009Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Lactate Shuttling Drives the Browning of White Adipose Tissue after Burn Trauma.
Dalia Barayan, A. Abdullahi, Carly M. Knuth, Fadi Khalaf +3 more
2023American Journal of Physiology. Endocrinology and Metabolism16 citations
Semantic Scholar
Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels.
Do Thanh Phu, M. Wallbach, Chantal Depatie, Accalia Fu +2 more
2011Cellular Signalling14 citations
Semantic Scholar
Differentiation of Normal and Radioresistant Prostate Cancer Xenografts Using Magnetization Transfer-Prepared MRI
W. Lam, Wendy Oakden, Leedan Murray, J. Klein +6 more
2018Scientific Reports13 citations Open access
Semantic Scholar
Silencing the G-protein coupled receptor 3-salt inducible kinase 2 pathway promotes human β cell proliferation
Caterina Iorio, J. L. Rourke, L. Wells, Jun-ichi Sakamaki +4 more
2021Communications Biology9 citations Open access
Semantic Scholar
Of Mice and Men, Redux: Modern Challenges in β Cell Gene Targeting
J. Estall, R. Screaton
2020Endocrinology9 citations Open access
Semantic Scholar
SGK1: master and commander of the fate of helper T cells
Matthew D. Norton, R. Screaton
2014Nature Immunology9 citations
Semantic Scholar
Recent Developments in Islet Biology: A Review With Patient Perspectives
Lahari Basu, Vriti Bhagat, M. Ching, A. Di Giandomenico +21 more
2022Canadian Journal of Diabetes7 citations Open access
Semantic Scholar

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Accalia Fu×11
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Accalia Fu — researcher profile on SciRah
M. Montminy×8
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M. Montminy — researcher profile on SciRah
A. C. Ng×7
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A. C. Ng — researcher profile on SciRah
S. Baird×7
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S. Baird — researcher profile on SciRah

Chantal Depatie

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Chantal Depatie — researcher profile on SciRah

G. Canettieri×5

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G. Canettieri — researcher profile on SciRah

Courtney Reeks×5

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Courtney Reeks — researcher profile on SciRah

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R. Kulkarni — researcher profile on SciRah

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C. Stanners — researcher profile on SciRah

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N. Bardeesy — researcher profile on SciRah

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Ling Qi — researcher profile on SciRah

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